Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 22 Researches
7.7
USERS' SCORE
Good
Based on 297 Reviews
8.1
Supplement Facts
Serving Size:  1 Vegetable Capsule
Amount Per Serving
%DV
Biotin
5,000 mcg
16,667%
Calcium (as dicalcium phosphate)
148 mg
11%
Phosphorous (as dicalcium phosphate)
115 mg
9%

Top Medical Research Studies

9
Biotin restores hair growth post-deficiency
We encountered a case of a woman suffering from short bowel syndrome, who faced significant hair loss due to biotin deficiency while on home parenteral nutrition. After starting oral biotin supplementation of 10 mg/day for three weeks, we observed that her serum biotin levels increased, leading to noticeable new hair growth and resolution of other symptoms. Further intravenous biotin treatment maintained her on multivitamins that include biotin, preventing any future deficiency symptoms. This case highlights the importance of addressing biotin levels for hair health and overall well-being.
Read More
We explored the effects of biotin treatment on hair loss through a case study of a girl diagnosed with biotinidase deficiency. Despite having no notable family history of the condition, her symptoms included problematic dermatitis, yellow hair, and alopecia.

After identifying low levels of biotinase and significant metabolic increases, the girl was found to have two specific mutations in her BTD gene linked to this deficiency. Following the diagnosis, we observed a clear response to biotin supplementation, with an initial dosage of 20 mg per day.

Remarkably, her dermatitis improved within a month, and her hair color returned to normal after three months of treatment. These findings suggest that biotin replacement therapy can have significant positive outcomes in cases related to biotinidase deficiency, connecting biotin to effective hair restoration.
Read More
We investigated the effectiveness of biotin as a treatment for hair loss through a literature review focused on available studies. Our search led us to three specific studies that were relevant to the question of whether oral biotin truly supports hair growth or improves hair quality.

One of these studies stood out due to its rigorous design—a double-blind, placebo-controlled trial—but interestingly, it found no significant difference between participants taking biotin and those receiving a placebo when it came to hair growth. The other two studies we examined involved specific groups of patients, such as those on isotretinoin and women who had undergone sleeve gastrectomy. Despite their unique perspectives, these studies were also limited by potential biases and did not provide strong evidence in favor of biotin.

Overall, while biotin has gained immense popularity as a hair supplement among the public, it appears that if one hopes to find robust scientific support for its effectiveness, the evidence is lacking. High-quality research does not substantiate the common belief that biotin can significantly benefit hair health.
Read More

Most Useful Reviews

9
Effective against hair loss
39 people found this helpful
The best recommendation if you’re dealing with serious hair loss issues. The dosage beautifully supports nail health, while my skin feels silky and supple. I witnessed marked improvements by the second month, and I continued for the third to solidify these health benefits. These vitamins are considered the best globally, promising a 100% result. Investing in them is worthwhile, and I advise against experimenting with cheaper alternatives. Was it helpful? Definitely!
Read More
9
Reduced hair loss
14 people found this helpful
A vital vitamin for both beauty and health! Biotin is fantastic for hair and the nervous system. Hair loss and nerves are intertwined. Despite several dietary sources of biotin, I took 800 micrograms for effective results. After about a week, I noticed a threefold reduction in hair loss, and by three weeks, it halted completely. Importantly, I experienced no side effects, unlike with previous vitamin supplements that caused various issues.
Read More
9
Increased hair thickness
10 people found this helpful
It is working for me with no stomach upset. My hair is getting thicker, showing about 2.5 to 3 inches of regrowth. I've noticed considerable changes post-surgery; despite stress and antibiotics, my hair loss has ceased, and I can see regrowth. I'm thrilled with the results from Solgar's product!
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 22 Researches
7.7
  • All Researches
9.5
Biotin serum shows promising results
We investigated the effectiveness of the Dr. SKS Hair Booster Serum, which contains biotin and other micronutrients, for treating androgenetic alopecia in both men and women. This open-label study included 1,000 participants across multiple clinics in India who received the serum through mesotherapy or derma roller techniques for six months.

During the study, we closely monitored various indicators of hair health, including the amount of hair loss, hair growth rates, and overall hair density changes. Our findings revealed a significant reduction in hair fall and a notable improvement in hair density after treatment. Interestingly, 95% of participants reported satisfaction with the results after six months.

It’s important to note that while biotin is a key ingredient in the serum, the study did not isolate its effects from the other micronutrients, making it challenging to definitively attribute the positive outcomes solely to biotin. No major adverse effects were reported, suggesting a safe treatment profile.

Overall, the study demonstrated that the Dr. SKS Hair Booster Serum could be a viable option for those struggling with hair loss, providing promising results in the context of androgenetic alopecia.
Read More
9.5
Alopecia areata improvement with tofacitinib
We explored the effectiveness of tofacitinib, a treatment showing promise for alopecia areata (AA), particularly in cases that have proven resistant to other therapies. In one instance, a young adult male with resistant AA had not responded to treatments like oral and topical steroids, minoxidil, and oral troxasalen.

In this study, he received tofacitinib at a dose of 5 mg twice a day along with a biotin supplement. Remarkably, hair regrowth was noted just one month into the treatment, and by the three-month mark, over 90% of his hair had regrown. It’s worth mentioning that no side effects were recorded during the treatment period.

Our findings suggest that while biotin was administered alongside tofacitinib, its specific contributions to hair regrowth outcomes cannot be distinctly isolated. Thus, further research would be necessary to clarify the role of biotin in hair loss treatments.
Read More
We explored the effects of biotin treatment on hair loss through a case study of a girl diagnosed with biotinidase deficiency. Despite having no notable family history of the condition, her symptoms included problematic dermatitis, yellow hair, and alopecia.

After identifying low levels of biotinase and significant metabolic increases, the girl was found to have two specific mutations in her BTD gene linked to this deficiency. Following the diagnosis, we observed a clear response to biotin supplementation, with an initial dosage of 20 mg per day.

Remarkably, her dermatitis improved within a month, and her hair color returned to normal after three months of treatment. These findings suggest that biotin replacement therapy can have significant positive outcomes in cases related to biotinidase deficiency, connecting biotin to effective hair restoration.
Read More
9
Dr. SKS Hair Booster efficacy
We explored the effectiveness of Dr. SKS Hair Booster Serum, which contains biotin among other ingredients, in treating female pattern hair loss (FPHL) in women diagnosed with polycystic ovary syndrome (PCOS). Our study included 1,000 females aged 25-50 who experienced hair loss classified as Ludwig grades I and II.

Over six months, participants received the serum through injections in the scalp. We employed various assessment techniques, such as photography and microscopic evaluations, to measure changes in hair growth, thickness, and overall health before and after treatment.

After the treatment period, we observed significant improvements in several key hair parameters, including hair shaft diameter and terminal hair counts, as well as a decrease in unwanted hair. Notably, while biotin is a component of the formula, the study could not isolate its specific effects on hair loss due to the combination of multiple active ingredients.

Importantly, no adverse events were reported during the study, suggesting that Dr. SKS Hair Booster Serum is a safe option for those seeking to manage FPHL associated with PCOS. Overall, this study highlights a promising approach to treating hair loss in this specific patient population.
Read More
9
Biotin improves diffuse hair loss
We conducted a study to evaluate how effective biotin, when combined with dexpanthenol injections, is at treating diffuse hair loss. In our research, fifty participants suffering from this condition were divided into two groups to receive six weekly injections of different brands of the treatment—one from Pars Behvarzan and the other from Bayer.

After completing the treatment, we assessed the results through various methods like hair fall counts and hair density tests at one and eight weeks post-treatment. We were pleased to find that both treatments significantly helped in reducing hair loss and improving hair density. Specifically, the hair fall count showed remarkable improvement in both groups, while hair density also saw beneficial changes.

Interestingly, while both treatments were effective, we did notice that the Bayer group had a better improvement in the terminal-to-vellus hair ratio when compared to the Pars group at both follow-ups. Overall, our findings suggest that these injections of biotin and dexpanthenol are effective and safe for individuals experiencing diffuse hair loss, offering a reliable option for those looking to enhance their hair health.
Read More

User Reviews

USERS' SCORE
Good
Based on 297 Reviews
8.1
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Effective against hair loss
39 people found this helpful
The best recommendation if you’re dealing with serious hair loss issues. The dosage beautifully supports nail health, while my skin feels silky and supple. I witnessed marked improvements by the second month, and I continued for the third to solidify these health benefits. These vitamins are considered the best globally, promising a 100% result. Investing in them is worthwhile, and I advise against experimenting with cheaper alternatives. Was it helpful? Definitely!
Read More
9
Reduced hair loss
14 people found this helpful
A vital vitamin for both beauty and health! Biotin is fantastic for hair and the nervous system. Hair loss and nerves are intertwined. Despite several dietary sources of biotin, I took 800 micrograms for effective results. After about a week, I noticed a threefold reduction in hair loss, and by three weeks, it halted completely. Importantly, I experienced no side effects, unlike with previous vitamin supplements that caused various issues.
Read More
9
Increased hair thickness
10 people found this helpful
It is working for me with no stomach upset. My hair is getting thicker, showing about 2.5 to 3 inches of regrowth. I've noticed considerable changes post-surgery; despite stress and antibiotics, my hair loss has ceased, and I can see regrowth. I'm thrilled with the results from Solgar's product!
Read More
9
Best solution tried
8 people found this helpful
This is the best solution for hair loss I've tried! I take it for a month, then take a break, and repeat the course. The price-quality ratio is excellent. After two weeks of use, results come quickly, and I've also seen improvements in my skin and nails. It's a fantastic product; I recommend buying it!
Read More
9
Effective for hair
8 people found this helpful
Hello from Ukraine! I ordered this Biotin after hearing numerous positive reviews about it, which convinced me to get it for my sister, who suffers from seasonal hair loss and brittle nails. My sister takes one capsule—two during her menstrual cycle—and has noticed results after two weeks. She appreciates its efficacy, and we'll continue to order it. Highly recommend!
Read More

Frequently Asked Questions

9
Reduced hair loss
14 people found this helpful
A vital vitamin for both beauty and health! Biotin is fantastic for hair and the nervous system. Hair loss and nerves are intertwined. Despite several dietary sources of biotin, I took 800 micrograms for effective results. After about a week, I noticed a threefold reduction in hair loss, and by three weeks, it halted completely. Importantly, I experienced no side effects, unlike with previous vitamin supplements that caused various issues.
9
Best solution tried
8 people found this helpful
This is the best solution for hair loss I've tried! I take it for a month, then take a break, and repeat the course. The price-quality ratio is excellent. After two weeks of use, results come quickly, and I've also seen improvements in my skin and nails. It's a fantastic product; I recommend buying it!
9
Notable improvement
6 people found this helpful
This biotin is of high quality. Solgar is an excellent brand. This super biotin is the best I’ve used for hair loss. After taking one capsule daily for three weeks, the results are remarkable. I've noticed a significant improvement in my hair and skin, and my nails have stopped peeling and are growing faster. My hair loss has ceased, and new hair is emerging. I take it twice yearly, in spring and autumn.
9
Effective for hair regeneration
2 people found this helpful
These vitamins do an excellent job! I took them during the winter when I experienced significant hair loss and weak nails, plus I had acne. After a month, I noticed new hair growth, and my nails became stronger. I regret not continuing the supplements to further enhance the effects. However, they did not help with acne.
9
Recommended improvement
1 people found this helpful
I decided to take this for severe hair loss. After a month, my hair loss almost completely stopped. I recommend it! Those who upvote this will have a successful day. Don’t believe it? Try it for yourself!
9
Highly recommended
4 people found this helpful
I give it a perfect score! Biotin is incredible—it’s the best supplement I’ve ever taken. After three weeks of use, I've observed noticeable results—my nails no longer split and grow more quickly. Most importantly, my hair loss has stopped, and I've seen the growth of many new strands! I take it biannually: in spring and autumn.
9
Good results
6 people found this helpful
Amazing! These are the only pills that’ve effectively addressed my hair loss problem. After trying countless remedies, the key is to start with a strength of 10,000, follow up with 5000, and then transition to 3000. Gradually reduce if it’s working, and give a like.
9
Effective hair treatment
1 people found this helpful
As a measure against hair loss, I purchase this product with proline and take it. It was surprisingly effective, and I was amazed at the small amount of hair that fell out after shampooing. My hair has become stronger, and I recognise it as an effective solution.
9
Noticeable improvement
1 people found this helpful
I ordered this product on my trichologist's advice due to severe hair loss. The preparation contains biotin in a daily dosage of 5000 mg. The quality is excellent; after a month, I noticed improvement. My hair became stronger and stopped falling out rapidly, with new hair beginning to grow. Additionally, my nails strengthened and my facial skin cleared up.
We investigated the effectiveness of biotin as a treatment for hair loss through a literature review focused on available studies. Our search led us to three specific studies that were relevant to the question of whether oral biotin truly supports hair growth or improves hair quality.

One of these studies stood out due to its rigorous design—a double-blind, placebo-controlled trial—but interestingly, it found no significant difference between participants taking biotin and those receiving a placebo when it came to hair growth. The other two studies we examined involved specific groups of patients, such as those on isotretinoin and women who had undergone sleeve gastrectomy. Despite their unique perspectives, these studies were also limited by potential biases and did not provide strong evidence in favor of biotin.

Overall, while biotin has gained immense popularity as a hair supplement among the public, it appears that if one hopes to find robust scientific support for its effectiveness, the evidence is lacking. High-quality research does not substantiate the common belief that biotin can significantly benefit hair health.
We investigated the effects of biotin as part of a combination therapy aimed at tackling hair loss, particularly in those suffering from androgenic alopecia (AGA). This condition often leads to thinning hair and changes in the hair growth cycle, a problem linked to the hormone dihydrotestosterone (DHT), especially in men.

Each of the key components studied—arginine, arterial extract, and biotin tripeptide-1—was combined with low-level light therapy (LLLT) and was successful in enhancing essential cellular functions like mitochondrial performance, cell growth, and collagen production in skin cells.

Importantly, we noted that biotin worked alongside other substances, and we could see significant improvements in hair follicles. We observed reductions in inflammatory markers and increases in products that promote hair growth. This combined approach holds promise as a comprehensive solution to AGA, effectively addressing both hormonal and cell-based factors contributing to hair loss.
7
Biotin showed no significant benefits
We explored the effects of biotin on hair growth through a randomized, crossover clinical trial that involved different treatment groups. The trial compared 5% topical minoxidil alone, 5 mg oral biotin alone, and a combination of both treatments to see how they impacted hair growth in men.

Despite the inclusion of biotin in the study, the outcomes did not show a significant benefit for hair growth when biotin was used alone. The results suggest that while topical minoxidil may exhibit effective hair growth stimulation, the isolated effects of oral biotin in conjunction with or without minoxidil warrant further study to clarify its actual role.

Consequently, we can conclude that although biotin is often promoted as a hair growth aid, this particular research did not find strong evidence to support its effectiveness on its own, particularly when compared to the known benefits of topical minoxidil.
We observed that biotin, a crucial B vitamin, could play an important role in addressing hair loss, especially when linked to deficiencies. The study indicates that hair loss treatments may benefit significantly from biotin supplementation if a deficiency is present. This means that identifying low levels of biotin through patient history and blood tests is essential before starting treatment.

When addressing skin conditions like seborrheic dermatitis and comedonal acne, biotin appears to affect the underlying metabolic processes, potentially offering relief. Its good tolerability and lack of risk for overdose make biotin an appealing option for treatment, but it’s important that any supplementation is guided by healthcare professionals to ensure safety and effectiveness.

We need to take a cautious approach, focusing on diagnosing and confirming any deficiencies rather than assuming that biotin will be beneficial in all hair loss cases. Although many anecdotal reports exist about biotin's effectiveness, without clear evidence for all individuals, a tailored approach ensures the best outcomes.
We observed the occurrence of hair loss in 156 women following laparoscopic sleeve gastrectomy (LSG), a popular procedure for weight loss. Our goal was to determine how common hair loss is after this surgery and whether supplementing with biotin could help.

After undergoing LSG, a significant 72% of the patients reported experiencing hair loss, with most noticing it between three and four months post-surgery. Fortunately, none of the women developed permanent hair loss, but on average, they experienced this condition for about 5.5 months.

To explore biotin's effectiveness, we prescribed 1000 mcg/day of biotin to 22 women who had hair loss linked to biotin deficiency. Only 5 of these women, which is 23%, noticed a significant improvement. Interestingly, there were also 29 women who started taking biotin on their own, even when their blood levels were normal, and 11 of them (38%) reported a meaningful reduction in hair loss.

When we compared the results of biotin use in women with and without deficiency, there was no significant difference in outcomes. Overall, while temporary hair loss after LSG is common, our findings suggest that biotin supplementation does not have a strong effect in reducing this issue.

References

  1. Yelich A, Jenkins H, Holt S, Miller R. Biotin for Hair Loss: Teasing Out the Evidence. J Clin Aesthet Dermatol. 2024;17:56.
  2. Qiu S, Pan Z, Jiang X, Lv G, Feng A, et al. The synergistic effect of phototherapy and active substances on hair growth. J Photochem Photobiol B. 2024;259:113008. doi:10.1016/j.jphotobiol.2024.113008
  3. Valentim FO, Miola AC, Miot HA, Schmitt JV. Efficacy of 5% topical minoxidil versus 5 mg oral biotin versus topical minoxidil and oral biotin on hair growth in men: randomized, crossover, clinical trial. An Bras Dermatol. 2024;99:581. doi:10.1016/j.abd.2023.07.008
  4. Khare S. Efficacy of Dr. SKS Hair Booster Serum in the Treatment of Female Pattern Alopecia in Patients With PCOS: An Open-Label, Non-randomized, Prospective Study. Cureus. 2023;15:e44941. doi:10.7759/cureus.44941
  5. Tr P, Ts R, K SK, Prasanna H. A Comparative Study of Topical Procapil With Platelet-Rich Plasma Therapy Versus Topical Redensyl, Saw Palmetto, and Biotin With Platelet-Rich Plasma Therapy in the Treatment of Androgenetic Alopecia. Cureus. 2023;15:e38696. doi:10.7759/cureus.38696
  6. Khare S. The Efficacy and Safety of Dr. SKS Hair Booster Serum (a Cocktail of Micronutrients and Multivitamins) in Adult Males and Females With Androgenetic Alopecia: An Open-Label, Non-randomized, Prospective Study. Cureus. 2023;15:e37424. doi:10.7759/cureus.37424
  7. Sahay G. Resistant Alopecia Areata Treated with Tofacitinib. Int J Trichology. 2022;14:181. doi:10.4103/ijt.ijt_63_22
  8. Jo H, Kim SY, Kang BH, Baek C, Kwon JE, et al. Cicaria, a Novel Strain Derived from the Human Microbiome, and Its Efficacy as a Treatment for Hair Loss. Molecules. 2022;27. doi:10.3390/molecules27165136
  9. Samadi A, Ketabi Y, Firooz R, Firooz A. Efficacy of intramuscular injections of biotin and dexpanthenol in the treatment of diffuse hair loss: A randomized, double-blind controlled study comparing two brands. Dermatol Ther. 2022;35:e15695. doi:10.1111/dth.15695
  10. Starace M, Gurioli C, Carpanese MA, Bruni F, Piraccini BM, et al. Short anagen syndrome: A case series and algorithm for diagnosis. Pediatr Dermatol. 2021;38:1157. doi:10.1111/pde.14750
  11. Aksac SE, Bilgili SG, Yavuz GO, Yavuz IH, Aksac M, et al. Evaluation of biophysical skin parameters and hair changes in patients with acne vulgaris treated with isotretinoin, and the effect of biotin use on these parameters. Int J Dermatol. 2021;60:980. doi:10.1111/ijd.15485
  12. Yang Y, Yang JY, Chen XJ. Biotinidase deficiency characterized by skin and hair findings. Clin Dermatol. 2020;38:477. doi:10.1016/j.clindermatol.2020.03.004
  13. Şen O, Türkçapar AG. Hair Loss After Sleeve Gastrectomy and Effect of Biotin Supplements. J Laparoendosc Adv Surg Tech A. 2021;31:296. doi:10.1089/lap.2020.0468
  14. Marotta JC, Patel G, Carvalho M, Blakeney S. Clinical Efficacy of a Topical Compounded Formulation in Male Androgenetic Alopecia: Minoxidil 10%, Finasteride 0.1%, Biotin 0.2%, and Caffeine Citrate 0.05% Hydroalcoholic Solution. Int J Pharm Compd. 2020;24:69.
  15. Piraccini BM, Berardesca E, Fabbrocini G, Micali G, Tosti A. Biotin: overview of the treatment of diseases of cutaneous appendages and of hyperseborrhea. G Ital Dermatol Venereol. 2019;154:557. doi:10.23736/S0392-0488.19.06434-4
  16. Sant'Anna Addor FA, Donato LC, Melo CSA. Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium. Clin Cosmet Investig Dermatol. 2018;11:431. doi:10.2147/CCID.S173082
  17. Hayashi A, Mikami Y, Miyamoto K, Kamada N, Sato T, et al. Intestinal Dysbiosis and Biotin Deprivation Induce Alopecia through Overgrowth of Lactobacillus murinus in Mice. Cell Rep. 2017;20:1513. doi:10.1016/j.celrep.2017.07.057
  18. Castro-Gago M, Pérez-Gay L, Gómez-Lado C, Castiñeiras-Ramos DE, Otero-Martínez S, et al. The influence of valproic acid and carbamazepine treatment on serum biotin and zinc levels and on biotinidase activity. J Child Neurol. 2011;26:1522. doi:10.1177/0883073811409227
  19. Castro-Gago M, Gómez-Lado C, Eirís-Puñal J, Díaz-Mayo I, Castiñeiras-Ramos DE. Serum biotinidase activity in children treated with valproic acid and carbamazepine. J Child Neurol. 2010;25:32. doi:10.1177/0883073809336118
  20. Schulpis KH, Karikas GA, Tjamouranis J, Regoutas S, Tsakiris S. Low serum biotinidase activity in children with valproic acid monotherapy. Epilepsia. 2001;42:1359.
  21. Khalidi N, Wesley JR, Thoene JG, Whitehouse WM, Baker WL. Biotin deficiency in a patient with short bowel syndrome during home parenteral nutrition. JPEN J Parenter Enteral Nutr. 1984;8:311.
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