Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.3
USERS' SCORE
Moderately Good
Based on 69 Reviews
7.8
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
15
Total Fat
1.5 g
2%**
Cholesterol
5 mg
2%
Total Omega 3 Polyunsaturates† providing: EPA (eicosapentaenoic acid) DHA (docosahexaenoic acid)
950 mg 504 mg378 mg
*** *** ***
Top Medical Research Studies
8
We focused on how Resolvin D1 (RvD1), a pro-resolving lipid, impacts systemic lupus erythematosus (SLE). Our study measured RvD1 levels and T follicular helper (Tfh) cell counts in SLE patients versus healthy individuals.
We found that higher RvD1 levels correlated with lower disease activity and fewer Tfh cells. RvD1 was effective in reducing Tfh cell activity in a mouse model and inhibited Tfh differentiation in lab tests.
Overall, RvD1 appears to play a significant role in managing SLE by suppressing Tfh cells and influencing immune responses.
We found that higher RvD1 levels correlated with lower disease activity and fewer Tfh cells. RvD1 was effective in reducing Tfh cell activity in a mouse model and inhibited Tfh differentiation in lab tests.
Overall, RvD1 appears to play a significant role in managing SLE by suppressing Tfh cells and influencing immune responses.
Read More
7
We analyzed data from 18 randomized controlled trials involving 1018 rheumatoid arthritis (RA) patients to understand the effects of omega-3 supplementation. Our findings revealed that omega-3 significantly increased beneficial fatty acids, EPA, and DHA, while also decreasing harmful triglycerides and tender joint counts.
However, while some inflammation markers showed slight improvements, these changes were not statistically significant. Overall, omega-3 may help manage certain symptoms of RA, but the evidence remains mixed regarding its broader impact on inflammation.
However, while some inflammation markers showed slight improvements, these changes were not statistically significant. Overall, omega-3 may help manage certain symptoms of RA, but the evidence remains mixed regarding its broader impact on inflammation.
Read More
9
We explored the effects of a new, stable form of resolvin D1, called p-MPPF, on autoimmune encephalomyelitis, a condition affecting the nervous system. In our research, both p-MPPF and its unstable counterpart, RvD1, showed significant promise in reducing inflammation and improving symptoms.
This was evidenced by less severe disease progression, better spinal cord health, and changes in immune cell activity. Importantly, we discovered that both substances influenced immune cells in a way that avoids inflammation. Our findings suggest that these types of compounds could lead to improved treatments for autoimmune disorders.
This was evidenced by less severe disease progression, better spinal cord health, and changes in immune cell activity. Importantly, we discovered that both substances influenced immune cells in a way that avoids inflammation. Our findings suggest that these types of compounds could lead to improved treatments for autoimmune disorders.
Read More
Most Useful Reviews
7.5
Improved skin health
284 people found this helpful
After ordering this product post-childbirth, I aimed to help my depleted body. My doctor recommended this omega, and it's been beneficial. After a month of gradual vitamin intake, I feel much better. My skin and hair have improved, even if the course is somewhat pricey, the visible results are worth it. Best wishes to everyone reading!
Read More
9
Strengthened immune system
266 people found this helpful
This omega has proven excellent; I noticed results in just two weeks. My skin and hair improved significantly. While I initially took omega from another brand, I'm glad I switched to this one. It's effective and my daughter's health has benefited too at eight years old. I recommend it for the whole family!
Read More
9
Highly effective product
31 people found this helpful
One of the best omega-3 products. Very pure of mercury. It contains a high percentage of EPA and DHA, almost 1000 combined. You can meet your daily needs with just one pill, unlike other products that require two. The capsule is neither too big nor too small, making it easy to swallow without the taste of fish during burping. I recommend it, and this is my second order. If my comment helped you, please give it a positive like; I don't rush to write positive feedback unless I have thoroughly tried the product.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.3
- All Researches
9
We explored the effects of a new, stable form of resolvin D1, called p-MPPF, on autoimmune encephalomyelitis, a condition affecting the nervous system. In our research, both p-MPPF and its unstable counterpart, RvD1, showed significant promise in reducing inflammation and improving symptoms.
This was evidenced by less severe disease progression, better spinal cord health, and changes in immune cell activity. Importantly, we discovered that both substances influenced immune cells in a way that avoids inflammation. Our findings suggest that these types of compounds could lead to improved treatments for autoimmune disorders.
This was evidenced by less severe disease progression, better spinal cord health, and changes in immune cell activity. Importantly, we discovered that both substances influenced immune cells in a way that avoids inflammation. Our findings suggest that these types of compounds could lead to improved treatments for autoimmune disorders.
Read More
8
Omega-3s may improve SLE outcomes
We explored the effects of omega-3 fatty acids on systemic lupus erythematosus (SLE) using data from 418 participants. Our analysis focused on how different fatty acids relate to disease activity, pain, and sleep quality.
The results highlight that higher levels of long-chain omega-3 fatty acids, particularly DHA, are linked to better outcomes in SLE patients. Although our findings support the idea that omega-3s can be beneficial, more research is needed to confirm these benefits and their long-term effects.
This suggests that improving omega-3 intake through diet could be an effective strategy for managing SLE.
The results highlight that higher levels of long-chain omega-3 fatty acids, particularly DHA, are linked to better outcomes in SLE patients. Although our findings support the idea that omega-3s can be beneficial, more research is needed to confirm these benefits and their long-term effects.
This suggests that improving omega-3 intake through diet could be an effective strategy for managing SLE.
Read More
8
We explored the protective effects of omega-3 fatty acids on insulin-producing cells, particularly focusing on their role in reducing inflammation related to type 1 diabetes. Our findings suggest that omega-3s boost a protein called ARH3, which helps lower the expression of a harmful chemokine, CXCL9.
This mechanism seems to shield β cells from autoimmune attacks, potentially decreasing the risk of developing type 1 diabetes. Overall, while omega-3s show promise as an anti-inflammatory agent, the full impact on autoimmune disorders necessitates further investigation.
This mechanism seems to shield β cells from autoimmune attacks, potentially decreasing the risk of developing type 1 diabetes. Overall, while omega-3s show promise as an anti-inflammatory agent, the full impact on autoimmune disorders necessitates further investigation.
Read More
8
We explored the relationship between omega-3 fatty acids and autoimmune disorders, conducting a comprehensive review and Mendelian randomization analysis.
Our findings indicate that omega-3s provide benefits primarily for rheumatoid arthritis and systemic lupus erythematosus, improving disease activity and reducing inflammation.
However, there was no strong evidence supporting their effectiveness against other autoimmune conditions like psoriasis and multiple sclerosis. This suggests that while omega-3s may benefit certain illnesses, more research is needed for others.
Our findings indicate that omega-3s provide benefits primarily for rheumatoid arthritis and systemic lupus erythematosus, improving disease activity and reducing inflammation.
However, there was no strong evidence supporting their effectiveness against other autoimmune conditions like psoriasis and multiple sclerosis. This suggests that while omega-3s may benefit certain illnesses, more research is needed for others.
Read More
8
We conducted a multicentre, randomised, double-blind, placebo-controlled trial to examine how omega-3 fish oil, specifically from krill oil concentrate (KOC), affects patients with systemic lupus erythematosus (SLE).
Our research showed that KOC effectively corrected omega-3 deficiency and led to a decrease in disease activity for patients with more severe symptoms.
While outcomes were promising, we believe that further studies are necessary to confirm the long-term benefits of omega-3 supplementation for managing lupus.
Our research showed that KOC effectively corrected omega-3 deficiency and led to a decrease in disease activity for patients with more severe symptoms.
While outcomes were promising, we believe that further studies are necessary to confirm the long-term benefits of omega-3 supplementation for managing lupus.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 69 Reviews
7.8
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Improved skin health
284 people found this helpful
After ordering this product post-childbirth, I aimed to help my depleted body. My doctor recommended this omega, and it's been beneficial. After a month of gradual vitamin intake, I feel much better. My skin and hair have improved, even if the course is somewhat pricey, the visible results are worth it. Best wishes to everyone reading!
Read More
9
Strengthened immune system
266 people found this helpful
This omega has proven excellent; I noticed results in just two weeks. My skin and hair improved significantly. While I initially took omega from another brand, I'm glad I switched to this one. It's effective and my daughter's health has benefited too at eight years old. I recommend it for the whole family!
Read More
9
Highly effective product
31 people found this helpful
One of the best omega-3 products. Very pure of mercury. It contains a high percentage of EPA and DHA, almost 1000 combined. You can meet your daily needs with just one pill, unlike other products that require two. The capsule is neither too big nor too small, making it easy to swallow without the taste of fish during burping. I recommend it, and this is my second order. If my comment helped you, please give it a positive like; I don't rush to write positive feedback unless I have thoroughly tried the product.
Read More
9
Improved skin health
17 people found this helpful
GREAT OMEGA-3! ABSOLUTELY WORKING! I began taking Omega-3 on the advice of my dermatologist and gynecologist. I was shocked to find that the proper dosage is at least 3000 mg of EPA + DHA per day, which is significantly more than I previously took. Solgar's Omega-3 is recommended for its good reputation, and I take three capsules daily alongside other supplements. My skin has improved immensely and shows no problems even in winter. Although my diet isn’t ideal, my cholesterol levels were fine due to this supplement.
Read More
9
Improved sperm quality
7 people found this helpful
After a month of use, I achieved remarkable results! While planning for pregnancy, my husband had a poor spermogram with noticeable issues. He tried various supplements but saw no improvement. After we incorporated Omega-3 and vitamin C-ester into his regimen, the agglutination problem disappeared upon retesting. It was a huge win for us! Efficient and easy to swallow, with no unpleasant side effects reported.
Read More
Frequently Asked Questions
7.5
Improved skin health
284 people found this helpful
After ordering this product post-childbirth, I aimed to help my depleted body. My doctor recommended this omega, and it's been beneficial. After a month of gradual vitamin intake, I feel much better. My skin and hair have improved, even if the course is somewhat pricey, the visible results are worth it. Best wishes to everyone reading!
9
Strengthened immune system
266 people found this helpful
This omega has proven excellent; I noticed results in just two weeks. My skin and hair improved significantly. While I initially took omega from another brand, I'm glad I switched to this one. It's effective and my daughter's health has benefited too at eight years old. I recommend it for the whole family!
9
Enhanced mood
6 people found this helpful
Great Omega from a reliable brand! It’s expensive but lasts for 1.5 months when I take two capsules daily. Within a week, I felt a positive effect: my mood improved and I felt energised throughout the day, even with late nights, and my cravings for sweets vanished. I've also started taking vitamin D simultaneously. I'd recommend Omega to everyone!
9
Improved hair health
1 people found this helpful
Excellent Solgar Omega-3 EPA and DHA, Triple Strength, 950 mg, 100 capsules is the best product based on price and quality! I've been taking it for two months, and the results are remarkable! My hair has returned to normal, dandruff has disappeared, and I feel less fatigued. I wake up feeling rejuvenated. I will definitely order more!
9
Significant health improvement
5 people found this helpful
Best Omega by EPA and DHA, although not cheap. I've taken it for years alongside vitamin D. My allergies have disappeared, and my TSH levels have improved, allowing me to discontinue hormone replacement therapy for autoimmune thyroiditis.
9
Improved health
1 people found this helpful
Super! I take omega during my pregnancies and the effects are fantastic! My skin feels hydrated without any dryness, and my overall health is good with a stable mood. It's convenient that I need only one tablet, unlike the omega from Russian drugstores which contain far less. I've decided to use this every autumn.
9
Increased energy
3 people found this helpful
An excellent product! I’ve been taking it with my husband for about three weeks now, alongside vitamin D3 and multivitamins. My energy and efficiency have significantly increased, and my mood has improved! I feel cheerful in the mornings and full of strength throughout the day! I’ll definitely be ordering more! Thank you!
9
Improved sperm quality
7 people found this helpful
After a month of use, I achieved remarkable results! While planning for pregnancy, my husband had a poor spermogram with noticeable issues. He tried various supplements but saw no improvement. After we incorporated Omega-3 and vitamin C-ester into his regimen, the agglutination problem disappeared upon retesting. It was a huge win for us! Efficient and easy to swallow, with no unpleasant side effects reported.
8
Omega-3s may improve SLE outcomes
We explored the effects of omega-3 fatty acids on systemic lupus erythematosus (SLE) using data from 418 participants. Our analysis focused on how different fatty acids relate to disease activity, pain, and sleep quality.
The results highlight that higher levels of long-chain omega-3 fatty acids, particularly DHA, are linked to better outcomes in SLE patients. Although our findings support the idea that omega-3s can be beneficial, more research is needed to confirm these benefits and their long-term effects.
This suggests that improving omega-3 intake through diet could be an effective strategy for managing SLE.
The results highlight that higher levels of long-chain omega-3 fatty acids, particularly DHA, are linked to better outcomes in SLE patients. Although our findings support the idea that omega-3s can be beneficial, more research is needed to confirm these benefits and their long-term effects.
This suggests that improving omega-3 intake through diet could be an effective strategy for managing SLE.
8
We explored the protective effects of omega-3 fatty acids on insulin-producing cells, particularly focusing on their role in reducing inflammation related to type 1 diabetes. Our findings suggest that omega-3s boost a protein called ARH3, which helps lower the expression of a harmful chemokine, CXCL9.
This mechanism seems to shield β cells from autoimmune attacks, potentially decreasing the risk of developing type 1 diabetes. Overall, while omega-3s show promise as an anti-inflammatory agent, the full impact on autoimmune disorders necessitates further investigation.
This mechanism seems to shield β cells from autoimmune attacks, potentially decreasing the risk of developing type 1 diabetes. Overall, while omega-3s show promise as an anti-inflammatory agent, the full impact on autoimmune disorders necessitates further investigation.
7
We explored how diet might influence the risk of developing rheumatoid arthritis (RA) using a detailed Mendelian randomisation analysis. By examining data from extensive genome-wide association studies, we focused on twenty-two dietary factors. Our findings highlighted a notable genetic connection: higher intake of oily fish was linked to a lower risk of RA. Specifically, those who consumed oily fish showed a protective effect. Other dietary factors didn’t show significant relationships. This study emphasizes the potential benefits of adjusting one’s diet, particularly incorporating more oily fish for those at risk of RA.
7
Omega fatty acids show promise, need more research
We explored the potential benefits of omega-3 and omega-6 fatty acids on individuals suffering from Sjögren's syndrome, an autoimmune disorder affecting moisture production. After reviewing several clinical trials, we found that these fatty acids might help alleviate symptoms and inflammation.
However, results are mixed due to variations in study designs and a limited number of trials. Therefore, while promising, we still need further research to fully understand how omega-3 and omega-6 fatty acids can be effectively used in treating this condition.
However, results are mixed due to variations in study designs and a limited number of trials. Therefore, while promising, we still need further research to fully understand how omega-3 and omega-6 fatty acids can be effectively used in treating this condition.
8
We explored the relationship between omega-3 fatty acids and autoimmune disorders, conducting a comprehensive review and Mendelian randomization analysis.
Our findings indicate that omega-3s provide benefits primarily for rheumatoid arthritis and systemic lupus erythematosus, improving disease activity and reducing inflammation.
However, there was no strong evidence supporting their effectiveness against other autoimmune conditions like psoriasis and multiple sclerosis. This suggests that while omega-3s may benefit certain illnesses, more research is needed for others.
Our findings indicate that omega-3s provide benefits primarily for rheumatoid arthritis and systemic lupus erythematosus, improving disease activity and reducing inflammation.
However, there was no strong evidence supporting their effectiveness against other autoimmune conditions like psoriasis and multiple sclerosis. This suggests that while omega-3s may benefit certain illnesses, more research is needed for others.
7
Omega-3 shows limited effectiveness
We examined the effectiveness of omega-3 fatty acids in reducing autoimmune disease (AD) cases within a lengthy randomized trial. While vitamin D showed a notable reduction in AD incidence, omega-3 fatty acids did not demonstrate a statistically significant benefit during the initial phase.
However, after two additional years of monitoring, we found that those taking 1,000 mg/day of omega-3 saw a sustained reduction in AD instances, unlike the diminishing effects of vitamin D.
This suggests omega-3 fatty acids may provide some lasting advantages for AD prevention.
However, after two additional years of monitoring, we found that those taking 1,000 mg/day of omega-3 saw a sustained reduction in AD instances, unlike the diminishing effects of vitamin D.
This suggests omega-3 fatty acids may provide some lasting advantages for AD prevention.
8
We conducted a multicentre, randomised, double-blind, placebo-controlled trial to examine how omega-3 fish oil, specifically from krill oil concentrate (KOC), affects patients with systemic lupus erythematosus (SLE).
Our research showed that KOC effectively corrected omega-3 deficiency and led to a decrease in disease activity for patients with more severe symptoms.
While outcomes were promising, we believe that further studies are necessary to confirm the long-term benefits of omega-3 supplementation for managing lupus.
Our research showed that KOC effectively corrected omega-3 deficiency and led to a decrease in disease activity for patients with more severe symptoms.
While outcomes were promising, we believe that further studies are necessary to confirm the long-term benefits of omega-3 supplementation for managing lupus.
References
- Gilley KN, Fenton JI, Zick SM, Li K, Wang L, et al. Serum fatty acid profiles in systemic lupus erythematosus and patient reported outcomes: The Michigan Lupus Epidemiology & Surveillance (MILES) Program. Front Immunol. 2024;15:1459297. 10.3389/fimmu.2024.1459297
- You Y, Sarkar S, Deiter C, Elliott EC, Nicora CD, et al. Reduction of Chemokine CXCL9 Expression by Omega-3 Fatty Acids via ADP-Ribosylhydrolase ARH3 in MIN6 Insulin-Producing Cells. Proteomics. 2025;25:e202400053. 10.1002/pmic.202400053
- Wang Y, Hu S, Zhang W, Zhang B, Yang Z. Dietary factors and rheumatoid arthritis: new perspectives from a Mendelian randomisation analysis. Br J Nutr. 2025;133:107. 10.1017/S0007114524002721
- Nave CBD, Pereira P, Silva ML. The Effect of Polyunsaturated Fatty Acid (PUFA) Supplementation on Clinical Manifestations and Inflammatory Parameters in Individuals with Sjögren's Syndrome: A Literature Review of Randomized Controlled Clinical Trials. Nutrients. 2024;16. 10.3390/nu16213786
- Szczuko M, Kacprzak J, Przybylska A, Szczuko U, Pobłocki J, et al. The Influence of an Anti-Inflammatory Gluten-Free Diet with EPA and DHA on the Involvement of Maresin and Resolvins in Hashimoto's Disease. Int J Mol Sci. 2024;25. 10.3390/ijms252111692
- Hong K, Hun M, Wu F, Mao J, Wang Y, et al. Association between Omega-3 fatty acids and autoimmune disease: Evidence from the umbrella review and Mendelian randomization analysis. Autoimmun Rev. 2024;23:103651. 10.1016/j.autrev.2024.103651
- Zhang Q, Zhang Y, Zou M, Wu H, Liu C, et al. The chemically stable analogue of resolvin D1 ameliorates experimental autoimmune encephalomyelitis by mediating the resolution of inflammation. Int Immunopharmacol. 2024;140:112740. 10.1016/j.intimp.2024.112740
- Salmon J, Wallace DJ, Rus V, Cox A, Dykas C, et al. Correction of omega-3 fatty acid deficiency and improvement in disease activity in patients with systemic lupus erythematosus treated with krill oil concentrate: a multicentre, randomised, double-blind, placebo-controlled trial. Lupus Sci Med. 2024;11. 10.1136/lupus-2024-001201
- Wang W, Xu Y, Zhou J, Zang Y. Effects of omega-3 supplementation on lipid metabolism, inflammation, and disease activity in rheumatoid arthritis: a meta-analysis of randomized controlled trials. Clin Rheumatol. 2024;43:2479. 10.1007/s10067-024-07040-0
- Cervantes A, Hughes FM, Jin H, Purves JT. Specialized pro-resolution mediators in the bladder: effects of resolvin E1 on diabetic bladder dysfunction in the type 1 diabetic male Akita mouse model. BMC Urol. 2024;24:130. 10.1186/s12894-024-01519-3
- Chen Y, Li Z, Gao Y, Xu B, Zhang W, et al. Fish oil supplementation and risk of incident systemic lupus erythematosus: a large population-based prospective study. Nutr J. 2024;23:63. 10.1186/s12937-024-00965-x
- Kang T, Xi Y, Qian T, Lu S, Du M, et al. Exploring the link between dietary omega-3 and omega-6 fatty acid intake and rheumatoid arthritis risk: NHANES 1999-2020 study. Clin Exp Rheumatol. 2024;42:1720. 10.55563/clinexprheumatol/91tmfb
- Laevski AM, Doucet MR, Doucet MS, LeBlanc AA, Pineau PE, et al. Dietary omega-3 fatty acids modulate the production of platelet-derived microvesicles in an in vivo inflammatory arthritis model. Eur J Nutr. 2024;63:2221. 10.1007/s00394-024-03397-9
- Huang L, Wu J, Cao J, Sheng X, Wang M, et al. Resolvin D1 inhibits T follicular helper cell expansion in systemic lupus erythematosus. Scand J Rheumatol. 2024;53:276. 10.1080/03009742.2024.2344906
- Lin X, Zarghami A, Jelinek GA, Simpson-Yap S, Neate S, et al. Diet and omega-3 and vitamin D supplement use predict five-year fatigue and disability trajectories in people with multiple sclerosis. Mult Scler Relat Disord. 2024;86:105615. 10.1016/j.msard.2024.105615
- Costenbader KH, Cook NR, Lee IM, Hahn J, Walter J, et al. Vitamin D and Marine n-3 Fatty Acids for Autoimmune Disease Prevention: Outcomes Two Years After Completion of a Double-Blind, Placebo-Controlled Trial. Arthritis Rheumatol. 2024;76:973. 10.1002/art.42811
