Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.1
USERS' SCORE
Good
Based on 13 Reviews
8.6
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
15
 
Total Fat
1.5 g
2%**
Cholesterol
5 mg
2%
Total Omega 3 Polyunsaturates† providing: EPA (eicosapentaenoic acid) DHA (docosahexaenoic acid)
950 mg 504 mg378 mg
*** *** ***

Top Medical Research Studies

9.5
We examined the effects of eicosapentaenoic acid (EPA) on episodic migraine patients through a 12-week randomized double-blind trial. Seventy participants were divided into two groups, one receiving EPA and the other a placebo.

Those taking the EPA experienced significant decreases in migraine frequency, medication use, headache severity, and improvements in overall quality of life.

Notably, women benefitted particularly from this treatment. Overall, high-dose EPA showed promise as an effective preventive option for episodic migraines, with no major side effects observed.
Read More
8
Omega-3s reduce headache frequency
We conducted a randomized controlled trial to explore whether increasing omega-3 fatty acids would help reduce headaches in adults suffering from migraines.

Over 16 weeks, 182 participants followed three different dietary plans focusing on varying levels of omega-3s while monitoring headache impact.

Though the diets with higher omega-3 levels did show a reduction in headache frequency and severity, they didn't significantly improve overall quality of life. This suggests that omega-3s may help with headaches but not enhance daily functioning.
Read More
8
Omega-3 fish oil reduces headaches
We explored the effects of a 12-week omega-3 fish oil supplement, Omega3Q10, among older adults dealing with high blood pressure and cholesterol. The study included 97 participants, who were split between the omega-3 group and a control group receiving soybean oil.

While both groups saw improvements in cholesterol levels, those taking Omega3Q10 experienced greater benefits in managing blood pressure and reported fewer headaches. An impressive 95.5% of omega-3 participants were headache-free after the trial, compared to just 71.4% in the soybean oil group.

This suggests that omega-3 fish oil may be a valuable addition for older adults looking to improve both heart health and reduce headache symptoms.
Read More

Most Useful Reviews

9
Magic remedy
3 people found this helpful
Recommended by my doctor while planning a pregnancy, this omega-3 has been a game changer for me. Within a week, I realised my headaches had disappeared, which seemed to stem from various stresses and pressure drops. Now, after six months of use, I've found that headache relief is consistent, and I no longer require painkillers. Truly a magical remedy.
Read More
9
Headache vanished
1 people found this helpful
Although this omega isn't rich in DHA, it effectively banished my headaches completely. The taste is fine, and for the price, it proves to be a working solution, making it one of the best options I've come across.
Read More
10
Improved memory
After completing a course of omega-3, my memory significantly improved. My colleagues have noticed this change in my information retention, and importantly, my headaches have vanished altogether.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.1
  • All Researches
9.5
We examined the effects of eicosapentaenoic acid (EPA) on episodic migraine patients through a 12-week randomized double-blind trial. Seventy participants were divided into two groups, one receiving EPA and the other a placebo.

Those taking the EPA experienced significant decreases in migraine frequency, medication use, headache severity, and improvements in overall quality of life.

Notably, women benefitted particularly from this treatment. Overall, high-dose EPA showed promise as an effective preventive option for episodic migraines, with no major side effects observed.
Read More
9
Omega-3 diet improves headaches
We examined how adjusting omega-3 and omega-6 fatty acids influences chronic headaches and overall well-being. In a randomized trial with 67 participants suffering from severe headaches, those who increased omega-3 intake while decreasing omega-6 saw significant improvements in their headaches and reductions in psychological distress.

Over 12 weeks, participants in this dietary intervention reported better mental and physical health, which also helped decrease the number of headache days. Overall, this approach not only targets headache relief but also enhances quality of life.
Read More
8
Omega-3s reduce headache frequency
We conducted a randomized controlled trial to explore whether increasing omega-3 fatty acids would help reduce headaches in adults suffering from migraines.

Over 16 weeks, 182 participants followed three different dietary plans focusing on varying levels of omega-3s while monitoring headache impact.

Though the diets with higher omega-3 levels did show a reduction in headache frequency and severity, they didn't significantly improve overall quality of life. This suggests that omega-3s may help with headaches but not enhance daily functioning.
Read More
8
Omega-3 fish oil reduces headaches
We explored the effects of a 12-week omega-3 fish oil supplement, Omega3Q10, among older adults dealing with high blood pressure and cholesterol. The study included 97 participants, who were split between the omega-3 group and a control group receiving soybean oil.

While both groups saw improvements in cholesterol levels, those taking Omega3Q10 experienced greater benefits in managing blood pressure and reported fewer headaches. An impressive 95.5% of omega-3 participants were headache-free after the trial, compared to just 71.4% in the soybean oil group.

This suggests that omega-3 fish oil may be a valuable addition for older adults looking to improve both heart health and reduce headache symptoms.
Read More
8
Omega-3 reduces migraine frequency
We explored the effectiveness of omega-3 fatty acids in preventing chronic migraine attacks through a well-structured double-blind study. Sixty patients diagnosed with chronic migraines were split into two groups: one received omega-3 alongside amitriptyline, while the other got a placebo.

After 60 days, we observed that 66.7% of the omega-3 group reported more than an 80% reduction in headache days, compared to only 33.3% in the control group. This shows promise for omega-3 as a migraine preventive, though further study is needed to solidify these findings.
Read More

User Reviews

USERS' SCORE
Good
Based on 13 Reviews
8.6
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Magic remedy
3 people found this helpful
Recommended by my doctor while planning a pregnancy, this omega-3 has been a game changer for me. Within a week, I realised my headaches had disappeared, which seemed to stem from various stresses and pressure drops. Now, after six months of use, I've found that headache relief is consistent, and I no longer require painkillers. Truly a magical remedy.
Read More
9
Headache vanished
1 people found this helpful
Although this omega isn't rich in DHA, it effectively banished my headaches completely. The taste is fine, and for the price, it proves to be a working solution, making it one of the best options I've come across.
Read More
10
Improved memory
After completing a course of omega-3, my memory significantly improved. My colleagues have noticed this change in my information retention, and importantly, my headaches have vanished altogether.
Read More
10
Surge of cheerfulness
My experience with omega-3 has been greatly positive. We noticed increased cheerfulness and energy almost immediately. By the second week, my headaches were gone, reinforcing our decision to continue this supplement regularly.
Read More
10
Headaches disappeared
I stopped at this omega-3, as the brand is trustworthy and my health has improved; headaches have disappeared. They have no smell or taste, but initially, they are a bit hard to swallow and require plenty of water. However, after a while, I managed to adapt.
Read More

Frequently Asked Questions

9
Magic remedy
3 people found this helpful
Recommended by my doctor while planning a pregnancy, this omega-3 has been a game changer for me. Within a week, I realised my headaches had disappeared, which seemed to stem from various stresses and pressure drops. Now, after six months of use, I've found that headache relief is consistent, and I no longer require painkillers. Truly a magical remedy.
10
Surge of cheerfulness
My experience with omega-3 has been greatly positive. We noticed increased cheerfulness and energy almost immediately. By the second week, my headaches were gone, reinforcing our decision to continue this supplement regularly.
10
Headaches ceased
I recommend buying it! I've nearly finished the course of 100 tablets and will take a month’s break. During use, I noticed that my headaches ceased, and my hair stopped falling out rapidly. My nails became stronger as well, and I feel much better!
10
Improved memory
After completing a course of omega-3, my memory significantly improved. My colleagues have noticed this change in my information retention, and importantly, my headaches have vanished altogether.
0
Headaches unbearable
I find this product excellent for my family, but personally, it gives me headaches that I simply cannot bear.
7.5
Less frequent headaches
Good quality. While taking the drug, my headaches became much less frequent, and my skin's condition improved. I didn't experience any side effects.
7
EPA supplementation may reduce migraines
We conducted a randomized, placebo-controlled trial to explore the effects of daily 2000 mg of eicosapentaenoic acid (EPA) on chronic migraines. Over 8 weeks, participants recorded their headache symptoms, with some taking EPA and others receiving a placebo.

Our findings suggest that EPA may significantly reduce the frequency of migraine attacks and improve overall quality of life for chronic migraine sufferers. However, we believe that more research is needed for a clearer understanding of its benefits and dosage.
9.5
We examined the effects of eicosapentaenoic acid (EPA) on episodic migraine patients through a 12-week randomized double-blind trial. Seventy participants were divided into two groups, one receiving EPA and the other a placebo.

Those taking the EPA experienced significant decreases in migraine frequency, medication use, headache severity, and improvements in overall quality of life.

Notably, women benefitted particularly from this treatment. Overall, high-dose EPA showed promise as an effective preventive option for episodic migraines, with no major side effects observed.
This cross-sectional study explored whether eating more long-chain omega-3 fatty acids could help reduce headaches in the U.S. population.

We analyzed data from over 12,000 adults, looking at their reported headaches and dietary intake of omega-3s like EPA and DHA.

Our findings showed that higher intake of these omega-3 fats was linked to a lower chance of experiencing severe headaches or migraines, especially among non-Mexican Hispanics. This suggests that omega-3 fatty acids could play a role in headache prevention.
5
Omega-3 and curcumin reduce migraines
We examined the impact of omega-3 fatty acids and nano-curcumin on migraine patients, particularly focusing on a substance called TNF-α linked to neuroinflammation. Over two months, 74 episodic migraine sufferers were divided into four groups, receiving either omega-3, curcumin, their combination, or a placebo.

Notably, the combined treatment significantly reduced TNF-α levels and migraine attack frequency. However, neither omega-3 nor curcumin alone showed significant results. This suggests that combining these supplements could be a promising approach in managing migraines.
7
Fish oil shows promise for migraines
We investigated the effectiveness of fish oil supplementation for managing headache symptoms and improving blood lipid levels in migraine patients.

Participants were given either 1g of fish oil or a soybean oil placebo for 12 weeks.

At the end of the study, those taking fish oil reported notable improvements in the frequency, duration, and intensity of their migraine attacks, along with healthier blood lipid profiles.

This suggests fish oil could be a helpful addition to traditional migraine treatments.
8
Omega-3 reduces migraine frequency
We explored the effectiveness of omega-3 fatty acids in preventing chronic migraine attacks through a well-structured double-blind study. Sixty patients diagnosed with chronic migraines were split into two groups: one received omega-3 alongside amitriptyline, while the other got a placebo.

After 60 days, we observed that 66.7% of the omega-3 group reported more than an 80% reduction in headache days, compared to only 33.3% in the control group. This shows promise for omega-3 as a migraine preventive, though further study is needed to solidify these findings.

References

  1. Yeh EL, Yang CP, Lin SW, Wang HF. Feasibility of Fish Oil Supplementation on Headache Symptoms and Blood Lipids in Migraine Patients. Brain Behav. 2024;14:e70149. 10.1002/brb3.70149
  2. Mohammadnezhad G, Assarzadegan F, Koosha M, Esmaily H. Eicosapentaenoic acid versus placebo as adjunctive therapy in chronic migraine: A randomized controlled trial. Headache. 2025;65:153. 10.1111/head.14808
  3. Wang HF, Liu WC, Zailani H, Yang CC, Chen TB, et al. A 12-week randomized double-blind clinical trial of eicosapentaenoic acid intervention in episodic migraine. Brain Behav Immun. 2024;118:459. 10.1016/j.bbi.2024.03.019
  4. Sanders AE, Weatherspoon ED, Ehrmann BM, Soma PS, Shaikh SR, et al. Circulating Polyunsaturated Fatty Acids and Pain Intensity in Five Chronic Pain Conditions. J Pain. 2023;24:478. 10.1016/j.jpain.2022.10.008
  5. Faurot KR, Cole WR, MacIntosh BA, Dunlap M, Moore CB, et al. Targeted dietary interventions to reduce pain in persistent post-traumatic headache among service members: Protocol for a randomized, controlled parallel-group trial. Contemp Clin Trials. 2022;119:106851. 10.1016/j.cct.2022.106851
  6. Ramsden CE, Zamora D, Faurot KR, MacIntosh B, Horowitz M, et al. Dietary alteration of n-3 and n-6 fatty acids for headache reduction in adults with migraine: randomized controlled trial. BMJ. 2021;374:n1448. 10.1136/bmj.n1448
  7. Honarvar NM, Soveid N, Abdolahi M, Djalali M, Hatami M, et al. Anti-Neuroinflammatory Properties of n-3 Fatty Acids and Nano- Curcumin on Migraine Patients from Cellular to Clinical Insight: A Randomized, Double-Blind and Placebo-Controlled Trial. Endocr Metab Immune Disord Drug Targets. 2021;21:365. 10.2174/1871530320666200729144430
  8. Abdolahi M, Jafarieh A, Sarraf P, Sedighiyan M, Yousefi A, et al. The Neuromodulatory Effects of ω-3 Fatty Acids and Nano-Curcumin on the COX-2/ iNOS Network in Migraines: A Clinical Trial Study from Gene Expression to Clinical Symptoms. Endocr Metab Immune Disord Drug Targets. 2019;19:874. 10.2174/1871530319666190212170140
  9. Sanders AE, Shaikh SR, Slade GD. Long-chain omega-3 fatty acids and headache in the U.S. population. Prostaglandins Leukot Essent Fatty Acids. 2018;135:47. 10.1016/j.plefa.2018.06.008
  10. Mann JD, Faurot KR, MacIntosh B, Palsson OS, Suchindran CM, et al. A sixteen-week three-armed, randomized, controlled trial investigating clinical and biochemical effects of targeted alterations in dietary linoleic acid and n-3 EPA+DHA in adults with episodic migraine: Study protocol. Prostaglandins Leukot Essent Fatty Acids. 2018;128:41. 10.1016/j.plefa.2017.11.002
  11. Shen T, Xing G, Zhu J, Zhang S, Cai Y, et al. Effects of 12-week supplementation of marine Omega-3 PUFA-based formulation Omega3Q10 in older adults with prehypertension and/or elevated blood cholesterol. Lipids Health Dis. 2017;16:253. 10.1186/s12944-017-0617-0
  12. Soveyd N, Abdolahi M, Djalali M, Hatami M, Tafakhori A, et al. The Combined Effects of ω -3 Fatty Acids and Nano-Curcumin Supplementation on Intercellular Adhesion Molecule-1 (ICAM-1) Gene Expression and Serum Levels in Migraine Patients. CNS Neurol Disord Drug Targets. 2018;16:1120. 10.2174/1871527317666171213154749
  13. Abdolahi M, Tafakhori A, Togha M, Okhovat AA, Siassi F, et al. The synergistic effects of ω-3 fatty acids and nano-curcumin supplementation on tumor necrosis factor (TNF)-α gene expression and serum level in migraine patients. Immunogenetics. 2017;69:371. 10.1007/s00251-017-0992-8
  14. Soares AA, Louçana PMC, Nasi EP, Sousa KMH, Sá OMS, et al. A double- blind, randomized, and placebo-controlled clinical trial with omega-3 polyunsaturated fatty acids (OPFA ɷ-3) for the prevention of migraine in chronic migraine patients using amitriptyline. Nutr Neurosci. 2018;21:219. 10.1080/1028415X.2016.1266133
  15. Ramsden CE, Zamora D, Makriyannis A, Wood JT, Mann JD, et al. Diet-induced changes in n-3- and n-6-derived endocannabinoids and reductions in headache pain and psychological distress. J Pain. 2015;16:707. 10.1016/j.jpain.2015.04.007
  16. Ramsden CE, Faurot KR, Zamora D, Palsson OS, MacIntosh BA, et al. Targeted alterations in dietary n-3 and n-6 fatty acids improve life functioning and reduce psychological distress among patients with chronic headache: a secondary analysis of a randomized trial. Pain. 2015;156:587. 10.1097/01.j.pain.0000460348.84965.47
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