Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
7.4
USERS' SCORE
Good
Based on 11 Reviews
8.9
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
15
 
Total Fat
1.5 g
2%**
Cholesterol
5 mg
2%
Total Omega 3 Polyunsaturates† providing: EPA (eicosapentaenoic acid) DHA (docosahexaenoic acid)
950 mg 504 mg378 mg
*** *** ***

Top Medical Research Studies

9
DHA reduces knee pain and swelling
We explored whether purified docosahexaenoic acid (DHA), an omega-3 fatty acid, can ease knee pain and swelling in a mouse model of arthritis. Mice with arthritis were treated with either oral or injected DHA, and we observed notable improvements in pain behavior and knee swelling.

This study highlights that DHA may reduce pain and inflammation in knee arthritis, suggesting it could be a helpful option for those suffering from rheumatoid arthritis. However, it’s essential to keep in mind that these results come from an animal model, and human studies are necessary.
Read More
8
Omega-3 reduces knee pain effectively
We conducted a rigorous clinical trial to investigate how omega-3 fish oil affects knee pain in people aged 40 and older. In this double-blind study with four groups, we found that those taking an omega-3-based product, AvailOm, experienced a notable reduction in pain intensity compared to a placebo.

By week eight, participants reported less discomfort and improved quality of life. Additionally, the intake of AvailOm led to better muscle strength and sleep quality, making it a promising option for alleviating persistent knee pain. Overall, omega-3 fish oil shows effective benefits for older adults struggling with knee pain.
Read More
8
Fish oil improves knee function
We explored the effects of omega-3 fish oil on knee osteoarthritis by evaluating 75 participants over 8 weeks. Divided into three groups, they took either 1,000 mg or 2,000 mg of fish oil each day.

Our findings showed that both dosages improved knee function and pain relief compared to a control group. However, the higher dose of 2,000 mg did not provide additional benefits over the 1,000 mg dose. Overall, participants reported high satisfaction with their results, and the treatment was deemed safe with minimal side effects.
Read More

Most Useful Reviews

10
Knee pain reduction
137 people found this helpful
I ordered this for my parents, and now their knees have stopped hurting. This omega-3 is excellent; I highly recommend it to everyone.
Read More
10
Joint pain relief
8 people found this helpful
Fantastic! I recommend it! This omega-3 is top-notch. After two months of taking 3 capsules daily, my mum's knee and shoulder joints no longer hurt.
Read More
9
Joint pain reduction
I order this for my mother regularly. The dosage is very good. Previously, she tried a smaller dosage from another brand but had nausea. This omega is different; after finishing a jar, the visual thickening in her finger joints decreased significantly, and new nails have grown straighter with nearly all pain gone.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
7.4
  • All Researches
9.5
Phytalgic promotes knee pain relief
We evaluated the effectiveness of Phytalgic, a supplement containing fish oil, on reducing knee pain in patients with osteoarthritis. In a randomized double-blind study of 81 participants, those taking Phytalgic reported lower usage of analgesics and NSAIDs compared to the placebo group.

Our findings showed significant reductions in pain, stiffness, and overall knee function, highlighting the potential benefit of Phytalgic in managing osteoarthritis symptoms. Overall, it seems that Phytalgic may offer an alternative relief option for those suffering from knee pain.
Read More
9
DHA reduces knee pain and swelling
We explored whether purified docosahexaenoic acid (DHA), an omega-3 fatty acid, can ease knee pain and swelling in a mouse model of arthritis. Mice with arthritis were treated with either oral or injected DHA, and we observed notable improvements in pain behavior and knee swelling.

This study highlights that DHA may reduce pain and inflammation in knee arthritis, suggesting it could be a helpful option for those suffering from rheumatoid arthritis. However, it’s essential to keep in mind that these results come from an animal model, and human studies are necessary.
Read More
8
Omega-3 reduces knee pain effectively
We conducted a rigorous clinical trial to investigate how omega-3 fish oil affects knee pain in people aged 40 and older. In this double-blind study with four groups, we found that those taking an omega-3-based product, AvailOm, experienced a notable reduction in pain intensity compared to a placebo.

By week eight, participants reported less discomfort and improved quality of life. Additionally, the intake of AvailOm led to better muscle strength and sleep quality, making it a promising option for alleviating persistent knee pain. Overall, omega-3 fish oil shows effective benefits for older adults struggling with knee pain.
Read More
8
GLM protects against OA pain
We investigated how the green-lipped mussel (GLM) can help in managing knee pain caused by osteoarthritis (OA). In our study using a rat model, we induced OA and then administered GLM to see its effects on pain and cartilage health.

Results showed that GLM significantly improved pain levels while protecting against cartilage damage and inflammation. It also reduced markers associated with destructive processes in the joints.

This suggests that GLM could be a beneficial treatment option for those suffering from OA and associated knee pain.
Read More
This study focused on whether l-serine and EPA could help relieve chronic knee and low-back pain. We learned that 120 adults participated in a randomized, double-blind, placebo-controlled trial. They received either the active treatment or a placebo over an 8-week period.

After analyzing results, we found that l-serine and EPA significantly reduced pain scores. This suggests that these two substances may effectively alleviate discomfort for those suffering from persistent knee pain.
Read More

User Reviews

USERS' SCORE
Good
Based on 11 Reviews
8.9
  • All Reviews
  • Positive Reviews
  • Negative Reviews
10
Knee pain reduction
137 people found this helpful
I ordered this for my parents, and now their knees have stopped hurting. This omega-3 is excellent; I highly recommend it to everyone.
Read More
10
Joint pain relief
8 people found this helpful
Fantastic! I recommend it! This omega-3 is top-notch. After two months of taking 3 capsules daily, my mum's knee and shoulder joints no longer hurt.
Read More
9
Joint pain reduction
I order this for my mother regularly. The dosage is very good. Previously, she tried a smaller dosage from another brand but had nausea. This omega is different; after finishing a jar, the visual thickening in her finger joints decreased significantly, and new nails have grown straighter with nearly all pain gone.
Read More
9
Significant improvement
I took Omega with vitamin D3 as advised by my doctor. I felt noticeable improvement after 2 weeks—my knee pain has reduced significantly, and I've also started to lose weight pleasantly.
Read More
7.5
Improved knee health
29 people found this helpful
I confirm my review with honesty. The large box contains 100 capsules, enough for 50 days. I've had a knock in my knees, but this has disappeared, and I've noticed better mood along with improvements to my skin, hair, and nails. The capsule smell is strong initially but fades after drinking water.
Read More

Frequently Asked Questions

9
Significant improvement
I took Omega with vitamin D3 as advised by my doctor. I felt noticeable improvement after 2 weeks—my knee pain has reduced significantly, and I've also started to lose weight pleasantly.
10
Joint pain relief
8 people found this helpful
Fantastic! I recommend it! This omega-3 is top-notch. After two months of taking 3 capsules daily, my mum's knee and shoulder joints no longer hurt.
7.5
Improved knee health
29 people found this helpful
I confirm my review with honesty. The large box contains 100 capsules, enough for 50 days. I've had a knock in my knees, but this has disappeared, and I've noticed better mood along with improvements to my skin, hair, and nails. The capsule smell is strong initially but fades after drinking water.
10
Knee pain reduction
137 people found this helpful
I ordered this for my parents, and now their knees have stopped hurting. This omega-3 is excellent; I highly recommend it to everyone.
9
Joint pain reduction
I order this for my mother regularly. The dosage is very good. Previously, she tried a smaller dosage from another brand but had nausea. This omega is different; after finishing a jar, the visual thickening in her finger joints decreased significantly, and new nails have grown straighter with nearly all pain gone.
8
Omega-3 reduces knee pain effectively
We conducted a rigorous clinical trial to investigate how omega-3 fish oil affects knee pain in people aged 40 and older. In this double-blind study with four groups, we found that those taking an omega-3-based product, AvailOm, experienced a notable reduction in pain intensity compared to a placebo.

By week eight, participants reported less discomfort and improved quality of life. Additionally, the intake of AvailOm led to better muscle strength and sleep quality, making it a promising option for alleviating persistent knee pain. Overall, omega-3 fish oil shows effective benefits for older adults struggling with knee pain.
8
Fish oil improves knee function
We explored the effects of omega-3 fish oil on knee osteoarthritis by evaluating 75 participants over 8 weeks. Divided into three groups, they took either 1,000 mg or 2,000 mg of fish oil each day.

Our findings showed that both dosages improved knee function and pain relief compared to a control group. However, the higher dose of 2,000 mg did not provide additional benefits over the 1,000 mg dose. Overall, participants reported high satisfaction with their results, and the treatment was deemed safe with minimal side effects.
This study focused on whether l-serine and EPA could help relieve chronic knee and low-back pain. We learned that 120 adults participated in a randomized, double-blind, placebo-controlled trial. They received either the active treatment or a placebo over an 8-week period.

After analyzing results, we found that l-serine and EPA significantly reduced pain scores. This suggests that these two substances may effectively alleviate discomfort for those suffering from persistent knee pain.
7
Omega-3 alleviates muscle soreness
We investigated how omega-3 fatty acids could affect knee pain related to delayed onset muscle soreness after eccentric exercises. Using a randomized and double-blinded study design, we observed 27 untrained men before and after they engaged in specific exercises.

Although participants reported their pain levels alongside measurements of knee range of motion and thigh circumference, we found that omega-3 supplementation showed promise in alleviating muscle soreness. Overall, the findings suggest that omega-3 may be helpful for enhancing recovery after such exercise.
7
Modest benefits of krill oil
We investigated whether krill oil could help reduce knee pain in adults experiencing mild to moderate osteoarthritis. Over six months, participants took either krill oil or a placebo in a well-structured double-blind trial.

While the results showed that krill oil was safe and led to some modest improvements in knee pain, stiffness, and physical function, the overall benefits were limited.

Thus, while krill oil may serve as a mild alternative for osteoarthritis pain relief, it’s essential to manage expectations regarding its effectiveness.
8
GLM protects against OA pain
We investigated how the green-lipped mussel (GLM) can help in managing knee pain caused by osteoarthritis (OA). In our study using a rat model, we induced OA and then administered GLM to see its effects on pain and cartilage health.

Results showed that GLM significantly improved pain levels while protecting against cartilage damage and inflammation. It also reduced markers associated with destructive processes in the joints.

This suggests that GLM could be a beneficial treatment option for those suffering from OA and associated knee pain.
We examined whether high-dose fish oil could better relieve knee osteoarthritis symptoms than a low dose. In a thorough trial involving 202 participants, they were divided into groups receiving either high-dose (4.5 g omega-3) or low-dose fish oil (0.45 g omega-3) for up to two years.

While both groups experienced some improvement in knee pain and function, the low-dose group responded better overall. There was no significant difference in cartilage loss or other health outcomes, leading us to conclude that higher doses may not be more effective and warrant further research into alternative oil blends.

References

  1. Pérez-Piñero S, Muñoz-Carrillo JC, Victoria-Montesinos D, García-Muñoz AM, Andreu-Caravaca L, et al. Efficacy of Extract and/or an Omega-3-Based Product for Improving Pain and Function in People Older Than 40 Years with Persistent Knee Pain: A Randomized Double-Blind Controlled Clinical Trial. Nutrients. 2023;15. 10.3390/nu15173848
  2. Stonehouse W, Benassi-Evans B, Bednarz J, Vincent AD, Hall S, et al. Krill oil improved osteoarthritic knee pain in adults with mild to moderate knee osteoarthritis: a 6-month multicenter, randomized, double-blind, placebo-controlled trial. Am J Clin Nutr. 2022;116:672. 10.1093/ajcn/nqac125
  3. Jhun J, Na HS, Cho KH, Kim J, Moon YM, et al. A green-lipped mussel reduces pain behavior and chondrocyte inflammation and attenuated experimental osteoarthritis progression. PLoS One. 2021;16:e0259130. 10.1371/journal.pone.0259130
  4. VanDusseldorp TA, Escobar KA, Johnson KE, Stratton MT, Moriarty T, et al. Impact of Varying Dosages of Fish Oil on Recovery and Soreness Following Eccentric Exercise. Nutrients. 2020;12. 10.3390/nu12082246
  5. Sasahara I, Yamamoto A, Takeshita M, Suga Y, Suzuki K, et al. l-Serine and EPA Relieve Chronic Low-Back and Knee Pain in Adults: A Randomized, Double-Blind, Placebo-Controlled Trial. J Nutr. 2020;150:2278. 10.1093/jn/nxaa156
  6. Valdes AM, Ravipati S, Menni C, Abhishek A, Metrustry S, et al. Association of the resolvin precursor 17-HDHA, but not D- or E- series resolvins, with heat pain sensitivity and osteoarthritis pain in humans. Sci Rep. 2017;7:10748. 10.1038/s41598-017-09516-3
  7. Sibille KT, King C, Garrett TJ, Glover TL, Zhang H, et al. Omega-6: Omega-3 PUFA Ratio, Pain, Functioning, and Distress in Adults With Knee Pain. Clin J Pain. 2018;34:182. 10.1097/AJP.0000000000000517
  8. Peanpadungrat P. Efficacy and Safety of Fish Oil in Treatment of Knee Osteoarthritis. J Med Assoc Thai. 2015;98 Suppl 3:S110.
  9. Hill CL, March LM, Aitken D, Lester SE, Battersby R, et al. Fish oil in knee osteoarthritis: a randomised clinical trial of low dose versus high dose. Ann Rheum Dis. 2016;75:23. 10.1136/annrheumdis-2014-207169
  10. Torres-Guzman AM, Morado-Urbina CE, Alvarado-Vazquez PA, Acosta-Gonzalez RI, Chávez-Piña AE, et al. Chronic oral or intraarticular administration of docosahexaenoic acid reduces nociception and knee edema and improves functional outcomes in a mouse model of Complete Freund's Adjuvant-induced knee arthritis. Arthritis Res Ther. 2014;16:R64. 10.1186/ar4502
  11. Jacquet A, Girodet PO, Pariente A, Forest K, Mallet L, et al. Phytalgic, a food supplement, vs placebo in patients with osteoarthritis of the knee or hip: a randomised double-blind placebo-controlled clinical trial. Arthritis Res Ther. 2009;11:R192. 10.1186/ar2891
  12. Tartibian B, Maleki BH, Abbasi A. The effects of ingestion of omega-3 fatty acids on perceived pain and external symptoms of delayed onset muscle soreness in untrained men. Clin J Sport Med. 2009;19:115. 10.1097/JSM.0b013e31819b51b3
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