' 
SCIENTIFIC SCORE
Questionable
Based on 2 Researches
6
USERS' SCORE
Excellent
Based on 19 Reviews
9
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Vitamin B6 (as pyridoxine HCl)
25 mg
1,471%
Top Medical Research Studies
4
Vitamin B6 risks in pregnancy
The potential hazards of high doses of vitamin B6 in treating nausea and vomiting in pregnancy: A systematic review.
Focus on vitamin B6 effects
We investigated the use of vitamin B6 as a common treatment for nausea and vomiting during pregnancy. There has been an ongoing discussion about how effective high doses of this vitamin actually are, and we wanted to shed light on this issue.
Through a systematic review of literature, we examined various studies, focusing on reports that highlighted the effects of high doses of vitamin B6 on pregnant women experiencing nausea. While we found that many women do turn to vitamin B6 to alleviate their symptoms, particularly during the challenging first trimester, the data also raised serious concerns about potential side effects.
A significant portion of the studies reviewed documented adverse reactions in women taking excessive amounts of vitamin B6. These included neurological symptoms such as burning sensations, tingling, and coordination problems. Alarmingly, we also noted a few cases of miscarriage and intrauterine demise among those studied.
Overall, while vitamin B6 is a widely used treatment for nausea during pregnancy, we must exercise caution. The risks associated with high doses cannot be overlooked, particularly when it comes to the health of both the mother and the developing fetus.
Through a systematic review of literature, we examined various studies, focusing on reports that highlighted the effects of high doses of vitamin B6 on pregnant women experiencing nausea. While we found that many women do turn to vitamin B6 to alleviate their symptoms, particularly during the challenging first trimester, the data also raised serious concerns about potential side effects.
A significant portion of the studies reviewed documented adverse reactions in women taking excessive amounts of vitamin B6. These included neurological symptoms such as burning sensations, tingling, and coordination problems. Alarmingly, we also noted a few cases of miscarriage and intrauterine demise among those studied.
Overall, while vitamin B6 is a widely used treatment for nausea during pregnancy, we must exercise caution. The risks associated with high doses cannot be overlooked, particularly when it comes to the health of both the mother and the developing fetus.
Read More
8
Pyridoxine reduces postoperative nausea
Pyridoxine Prevents Postoperative Nausea and Vomiting in Gynecological Laparoscopic Surgery: A Double-blind Randomized Controlled Trial.
Combined medication limits assessment
We examined the effects of pyridoxine, or vitamin B6, in reducing postoperative nausea and vomiting (PONV) for patients undergoing elective gynecological laparoscopic surgery. In this study, patients aged 18 to 65 were randomly assigned to receive either pyridoxine or a placebo (normal saline) before anesthesia.
All patients also received a regimen that included dexamethasone and ondansetron, two well-known anti-nausea medications. Reports from the patients indicated that those who received pyridoxine experienced a reduced incidence of nausea and vomiting following their surgery compared to those who received the placebo.
While our findings are promising, it is important to note that pyridoxine was used in conjunction with other medications, making it difficult to ascertain its effect in isolation. Future multicenter studies will help us confirm the effectiveness of pyridoxine in more diverse settings and populations.
All patients also received a regimen that included dexamethasone and ondansetron, two well-known anti-nausea medications. Reports from the patients indicated that those who received pyridoxine experienced a reduced incidence of nausea and vomiting following their surgery compared to those who received the placebo.
While our findings are promising, it is important to note that pyridoxine was used in conjunction with other medications, making it difficult to ascertain its effect in isolation. Future multicenter studies will help us confirm the effectiveness of pyridoxine in more diverse settings and populations.
Read More
Most Useful Reviews
9.5
Significant improvement
Worked for me for morning sickness. I took one tablet three times a day through my first trimester with significant improvement in my nausea. I couldn’t take Diclegis due to the sedating effect of doxylamine and found this worked well for me. Definitely worth a try!
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8.8
Right dosage found
If you've experienced morning sickness, you'll likely know that 25 mg of B6 is a common recommendation. Finding lower doses is difficult, but this product delivers. It’s effective for managing nausea, unlike other options. I highly recommend trying B6 if you're suffering.
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9.5
No vomiting
Excellent for pregnancy nausea. I have been taking these 3-4 times a day since 5 weeks along, alongside half a Unisom tablet twice daily. This is my fifth pregnancy, and it’s the first time I have reached 12 weeks without any vomiting! I’ve experienced some waves of nausea but credit the B6/Unisom combination, suggested by my doctor, for keeping it minimal this time.
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Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 2 Researches
6
8
Pyridoxine reduces postoperative nausea
Pyridoxine Prevents Postoperative Nausea and Vomiting in Gynecological Laparoscopic Surgery: A Double-blind Randomized Controlled Trial.
Combined medication limits assessment
We examined the effects of pyridoxine, or vitamin B6, in reducing postoperative nausea and vomiting (PONV) for patients undergoing elective gynecological laparoscopic surgery. In this study, patients aged 18 to 65 were randomly assigned to receive either pyridoxine or a placebo (normal saline) before anesthesia.
All patients also received a regimen that included dexamethasone and ondansetron, two well-known anti-nausea medications. Reports from the patients indicated that those who received pyridoxine experienced a reduced incidence of nausea and vomiting following their surgery compared to those who received the placebo.
While our findings are promising, it is important to note that pyridoxine was used in conjunction with other medications, making it difficult to ascertain its effect in isolation. Future multicenter studies will help us confirm the effectiveness of pyridoxine in more diverse settings and populations.
All patients also received a regimen that included dexamethasone and ondansetron, two well-known anti-nausea medications. Reports from the patients indicated that those who received pyridoxine experienced a reduced incidence of nausea and vomiting following their surgery compared to those who received the placebo.
While our findings are promising, it is important to note that pyridoxine was used in conjunction with other medications, making it difficult to ascertain its effect in isolation. Future multicenter studies will help us confirm the effectiveness of pyridoxine in more diverse settings and populations.
Read More
4
Vitamin B6 risks in pregnancy
The potential hazards of high doses of vitamin B6 in treating nausea and vomiting in pregnancy: A systematic review.
Focus on vitamin B6 effects
We investigated the use of vitamin B6 as a common treatment for nausea and vomiting during pregnancy. There has been an ongoing discussion about how effective high doses of this vitamin actually are, and we wanted to shed light on this issue.
Through a systematic review of literature, we examined various studies, focusing on reports that highlighted the effects of high doses of vitamin B6 on pregnant women experiencing nausea. While we found that many women do turn to vitamin B6 to alleviate their symptoms, particularly during the challenging first trimester, the data also raised serious concerns about potential side effects.
A significant portion of the studies reviewed documented adverse reactions in women taking excessive amounts of vitamin B6. These included neurological symptoms such as burning sensations, tingling, and coordination problems. Alarmingly, we also noted a few cases of miscarriage and intrauterine demise among those studied.
Overall, while vitamin B6 is a widely used treatment for nausea during pregnancy, we must exercise caution. The risks associated with high doses cannot be overlooked, particularly when it comes to the health of both the mother and the developing fetus.
Through a systematic review of literature, we examined various studies, focusing on reports that highlighted the effects of high doses of vitamin B6 on pregnant women experiencing nausea. While we found that many women do turn to vitamin B6 to alleviate their symptoms, particularly during the challenging first trimester, the data also raised serious concerns about potential side effects.
A significant portion of the studies reviewed documented adverse reactions in women taking excessive amounts of vitamin B6. These included neurological symptoms such as burning sensations, tingling, and coordination problems. Alarmingly, we also noted a few cases of miscarriage and intrauterine demise among those studied.
Overall, while vitamin B6 is a widely used treatment for nausea during pregnancy, we must exercise caution. The risks associated with high doses cannot be overlooked, particularly when it comes to the health of both the mother and the developing fetus.
Read More
User Reviews
USERS' SCORE
Excellent
Based on 19 Reviews
9
10
Effective for pregnancy
These were purchased to alleviate my wife's pregnancy nausea. Instead of overpriced store prescriptions, we opted for meclizine and this supplement. After trying many recommendations with no success, this approach has worked wonders for her severe dry heaving.
9.5
Cost-effective support
This was the most reasonably priced standalone B6 supplement and truly a lifesaver during my first trimester. It significantly reduced my nausea and stabilised my blood sugar fluctuations. I recommend consulting your doctor first before use.
9.5
Significant improvement
At eight weeks pregnant, I was continuously nauseous. After starting these pills on a Thursday, by Friday I had stopped throwing up. While I still experience mild nausea at times, the change has been remarkable. I can now manage activities with my children, which was unimaginable before.
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9.5
Miracle tablets
Pregnancy essential. These tablets were a miracle during the first trimester of my pregnancy. My doctor recommended 25mg of B6 and ginger twice daily to manage my morning sickness. I took both supplements in the morning and late afternoon and hardly felt nauseous. Co-workers and friends had terrible morning sickness, but I believe the B6 and ginger kept mine at bay. One morning, I tried omitting them and my nausea returned. Within half an hour of taking the missed doses, I felt fine again. I consider B6 a pregnancy essential and highly recommend this brand!
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9.5
Significant improvement
Great for morning sickness. These have significantly improved my nausea from morning sickness. I take 2-3 of these daily with a meal, and it’s been a night and day difference for me. Definitely worth the money!
