Solgar Vitamin B12
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Supplement Facts
Serving Size:   1 Vegetable Capsule
Amount Per Serving
%DV
Vitamin B12 (as cyanocobalamin)
500 mcg
20,833%

The product is found useful for the following medical conditions

Back Pain details

SCIENTIFIC SCORE
Moderately Effective
Based on 22 Researches
8.3
USERS' SCORE
Good
Based on 3 Reviews
8.7
9
B12 alleviates low back pain
Vitamin B12 in low back pain: a randomised, double-blind, placebo-controlled study.
Most Relevant Research
We evaluated the effectiveness of intramuscular vitamin B12 in treating low back pain among 60 patients aged 18 to 65 with mechanical pain lasting at least six months.

In this double-blind, placebo-controlled study, both groups showed improvement in pain levels. However, those receiving B12 had a more significant reduction in pain and dependence on pain medication compared to the placebo group.

Overall, B12 appears to be a safe option for alleviating low back pain, helping to reduce discomfort and medication use for those without nutritional deficiencies.
9.5
Helps back pain
Most Useful Review
I use this product for back pain caused by my job. It is extremely useful.

Leg Cramps details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.7
10
Cramps resolved
Most Useful Review
I ordered this for my daughter, who suffered from vitamin B12 deficiency, leading to issues with movement and leg cramps that could last for about an hour. After a full course of B12 injections with little success, she started using Solgar's vitamin B12. Happily, she is now free from leg cramps and has overcome her deficiency. Thank you, Solgar!

Anemia details

SCIENTIFIC SCORE
Moderately Effective
Based on 23 Researches
8.3
USERS' SCORE
Good
Based on 5 Reviews
8.6
9.5
Effectiveness of B12 in IGS
Severe pancytopenia at the presentation of Imerslund-Gräsbeck syndrome in a 23-month-old Italian boy.
Most Relevant Research
We explored the case of a 23-month-old boy suffering from severe pancytopenia linked to Imerslund-Gräsbeck syndrome, a rare condition caused by an inability to absorb vitamin B12. Upon diagnosis, the boy received vitamin B12 replacement therapy, which effectively addressed his symptoms and improved his health.

This case highlights the significance of early detection and treatment of IGS to avoid potential neurological damage. It's crucial to recognize this condition, even when neurological symptoms are absent, to provide timely care.
9.5
Anemia symptoms relieved
Most Useful Review
I didn’t consume much meat or fish, which led to some symptoms of anaemia. Since taking this vitamin B12 supplement, my symptoms have vanished. I believe this one is of high quality, as other brands didn’t have the same effect.

Bone Pain details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.6
9.5
Relief from pain
Most Useful Review
I use this product due to back pain caused by my job. It is very effective.

Chronic Fatigue Syndrome details

SCIENTIFIC SCORE
Questionable
Based on 9 Researches
6.8
USERS' SCORE
Good
Based on 2 Reviews
8.6
0
Vitamin B12 ineffective for CFS
N of 1 trials. Managing patients with chronic fatigue syndrome: two case reports.
Most Relevant Research
We explored the effectiveness of high-dose vitamin B12 injections on chronic fatigue syndrome (CFS) through two case reports that utilized N of 1 trials. This approach allowed us to make tailored treatment decisions based on individual responses to the therapy.

In one case, we found that high-dose vitamin B12 injections did not yield positive results, leaving the patient without significant relief from their symptoms. Conversely, in another case, we observed that nimodipine proved to be a very effective treatment for that patient’s chronic fatigue.

These findings suggest that while vitamin B12 may not be helpful for everyone suffering from CFS, other treatments like nimodipine can be beneficial. Thus, personalized treatment strategies are key in managing this complex and varied condition.
9.5
Increased energy levels
Most Useful Review
I began taking vitamin B12 and quickly noticed a positive effect. This vitamin is crucial for maintaining normal energy levels and a healthy nervous system. Almost immediately, I felt less fatigued and my mental clarity improved. B12 is vital for those with chronic fatigue syndrome, particularly as it aids in appetite regulation when deficiency is an issue. The capsules are easy to swallow and I’ve experienced no side effects. If you're suffering from fatigue or concentration issues, I highly recommend this supplement!

Heart Disease details

SCIENTIFIC SCORE
Questionable
Based on 12 Researches
6.5
USERS' SCORE
Good
Based on 2 Reviews
8.6
8
B12 may help heart damage
Vitamin B12 alleviates myocardial ischemia/reperfusion injury via the SIRT3/AMPK signaling pathway.
Most Relevant Research
We explored the potential of high doses of vitamin B12 to protect against heart damage caused by ischemia/reperfusion injury. By researching mice subjected to heart injury, we found that vitamin B12 showed promising effects in reducing oxidative stress and improving heart function.

Our findings suggest that this vitamin works through specific pathways that lessen inflammation and cell death in heart tissue. However, more studies are needed to fully understand its therapeutic value in treating heart disease.
8.8
Vitamin B12 benefits
Most Useful Review
Vitamin B12, a vital B-complex nutrient, aids energy metabolism and promotes a healthy nervous system. It, along with folic acid and vitamin B6, supports heart health by maintaining normal homocysteine levels. B12 is essential for the development and regeneration of red blood cells, which deliver oxygen throughout the body, particularly relevant for treating heart disease.
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