We investigated the impact of a treatment combining mannitol and vitamin B on piriformis syndrome (PS), which is characterized by sciatic nerve entrapment. In a study involving 22 patients, participants received a five-day intravenous infusion of mannitol alongside a six-week regimen of vitamin B, including B1, B2, and B12.
Our observations highlighted significant improvements in clinical assessments, particularly in tenderness and pain levels assessed by various tests and scales. Notably, the Numeric Rating Scale demonstrated a marked reduction in pain at rest, at night, and during activities, which were all statistically significant. Additionally, the swelling around the sciatic nerve also showed a noteworthy decrease.
While vitamin B12 was part of this combination treatment, we must acknowledge that the study's focus on mannitol alongside the vitamins makes it challenging to isolate vitamin B12's specific effects on back pain alone.
Nevertheless, the results suggest that the combined approach might be a promising alternative for managing PS effectively.
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B12 alleviates low back painVitamin B12 in low back pain: a randomised, double-blind, placebo-controlled study.
Significant positive treatment effects
We evaluated the effectiveness of intramuscular vitamin B12 in treating low back pain among 60 patients aged 18 to 65 with mechanical pain lasting at least six months.
In this double-blind, placebo-controlled study, both groups showed improvement in pain levels. However, those receiving B12 had a more significant reduction in pain and dependence on pain medication compared to the placebo group.
Overall, B12 appears to be a safe option for alleviating low back pain, helping to reduce discomfort and medication use for those without nutritional deficiencies.
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We investigated the effectiveness of Dolo-Neurobion, a combination of vitamins B1, B6, and B12 along with an analgesic, for patients with acute lumbosacral pain. The treatment began with a parenteral application followed by oral dosing.
Out of 53 patients, we observed that 77.4% experienced good to excellent relief from their pain, while 15.1% noted moderate effects. There were no notable side effects, which makes this treatment a viable option for managing pain associated with intrapelvic organ issues.
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Dexamethasone and B12 improve recoveryEffects of dexamethasone combined with vitamin B12 on percutaneous endoscopic interlaminar discectomy early outcomes: a randomized controlled trial.
Vitamin B12 effects are combined
We explored the effects of combining dexamethasone with vitamin B12 during epidural injections in patients undergoing a specific type of spinal surgery, known as percutaneous endoscopic interlaminar discectomy (PEID). This study aimed to determine whether this combination could alleviate low back and leg pain that often lingers after the surgery. Patients were randomly assigned to two groups: one received only the surgery (the single surgery group), while the other received the surgery along with the combined treatment of medication.
We found that patients who received the combination of dexamethasone and vitamin B12 experienced a notable reduction in early postoperative pain, which we measured using various scoring systems. Additionally, the injections appeared to decrease the levels of certain inflammatory factors in the body, suggesting a potential biological mechanism behind the relief they experienced. Early recovery metrics, like hospital stay duration and overall satisfaction, were also improved in those receiving the combined treatment.
Therefore, the results encourage considering the use of vitamin B12 along with dexamethasone for patients recovering from disc surgery, as it seems to enhance their recovery experience effectively.
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Vitamin B12 reverses back painProgressive Decrease in Function and Ambulation Potential: A Case of Subacute Combined Degeneration.
Moderate relevance to back pain
We explored the effects of vitamin B12 treatment on a patient experiencing severe back pain, along with other symptoms associated with subacute combined degeneration (SCD) from prolonged vitamin B12 deficiency. This case involved a 49-year-old man who faced a year of worsening weakness, pain, and gait abnormalities.
Upon diagnosis, he began receiving intramuscular vitamin B12 injections. Remarkably, within weeks, we observed significant improvements in his pain levels and mobility. This underscores the importance of recognizing vitamin B12 deficiency early since it can lead to debilitating conditions but is often reversible through timely treatment.
Our findings highlight how addressing nutrient deficiencies can enhance overall health and well-being. In this specific case, vitamin B12 not only alleviated back pain but also restored functioning, improving quality of life for the patient.
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