Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.6
USERS' SCORE
Moderately Good
Based on 1 Review
7.7
Supplement Facts
Serving Size:  1 Softgel
Amount Per Serving
%DV
Vitamin D3
25 mcg (1,000 IU)
125%

Top Medical Research Studies

8
Vitamin D deficiency affects symptoms
We aimed to understand how vitamin D deficiency (VDD) might influence symptoms like chest pain, anxiety, and fatigue in people living with coronary artery disease (CAD). In our investigation, we collected data from 90 CAD patients, focusing on their vitamin D levels and experiences with these symptoms.

The findings were quite revealing. A significant 80% of the participants were found to have low vitamin D levels. Interestingly, we discovered that lower vitamin D levels were linked to increased chest pain and heightened anxiety and fatigue. Specifically, there were strong negative relationships noted: as vitamin D levels dropped, chest pain, anxiety, and fatigue scores rose.

This suggests that addressing vitamin D deficiency might be an important step for managing cardiac-related symptoms in patients with CAD. As this connection unfolds, it seems valuable for healthcare providers to monitor vitamin D levels in CAD patients and consider interventions to correct deficiencies.
We investigated how vitamin D influences chest pain in individuals experiencing vaccine-related myocarditis after receiving the BNT162b2 COVID-19 vaccine. Our study involved analyzing vitamin D levels, immune profiles, and genetic factors in 60 patients who suffered from this condition.

A significant finding was that a high percentage of these patients, about 73.3%, were found to have low vitamin D levels. Particularly concerning was the observation that those patients who presented with chest pain were more likely to be vitamin D deficient. We also found that lower vitamin D levels were linked to higher peak levels of cardiac troponin T, a marker indicating heart stress.

Additionally, we explored genetic factors and found that certain genetic variations could either increase or increase the potential risk related to vitamin D status. These findings suggest that hypovitaminosis D may exacerbate inflammation and activate specific immune cells, leading to symptoms like chest pain.

Overall, our research supports the idea that improving vitamin D status could be crucial in reducing vaccine-related myocarditis and associated chest pain, revealing a path for potential preventive measures and treatment strategies.
9
Impact of Vitamin D on Chest Pain
We observed a case involving a middle-aged woman who reported persistent chest pain after starting a new weight training routine. Initially, her pain was localized around the right chest area, making it hard to pinpoint the exact cause. Standard examinations, including ultrasound and X-rays, didn’t uncover any issues, leading to further investigation with an MRI.

The MRI revealed swelling in the sternum, indicating a sternal stress fracture. In response to this finding, the patient was prescribed calcium and vitamin D supplements and advised to rest for six weeks. Following her recovery period, she gradually resumed her activities and was pleased to find herself pain-free after four months.

While it’s clear that vitamin D was part of her treatment regimen, we can only speculate on its specific role in alleviating her chest pain because it was combined with calcium. This means we can't definitively state that vitamin D alone was effective in this case.

Overall, this case serves as an interesting insight into the management of stress fractures in the chest area, showing the importance of proper supplementation and rest in recovery.

Most Useful Reviews

0
Severe side effects
I purchased this to aid a fracture, but it caused my heart to race, worsened nocturia, and induced sudden chest pain in the fractured area along with pain throughout my body and joint noises. Initially unsure of the cause, I identified this supplement as the culprit. I question the inclusion of deep sea fish and whether it underwent radiation testing, as the quality seems poor. I’ve taken D3 from other brands without such symptoms, despite this low dosage leading to ridiculous side effects.

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.6
  • All Researches
We investigated the effectiveness of vitamin D in relieving chest pain associated with a complex case of adult-onset hypophosphatemic osteomalacia (HO) in a 47-year-old woman suffering from Sjogren’s syndrome. In this case, the patient experienced progressively worsening pain in the chest, back, and legs, along with muscle weakness, raising questions about the underlying causes and appropriate treatment options.

After examining lab results, radiographic findings, and pathology, the diagnosis of adult-onset HO was confirmed. The treatment regimen included not only vitamin D but also alkalinization, steroids, neutral phosphate, and calcium supplements. Although the combination of treatments resulted in improved outcomes—such as pain relief and increased serum phosphorus levels—it’s difficult to isolate the effect of vitamin D specifically on chest pain, as it was one part of a broader therapeutic approach.

This case highlights the challenges of diagnosing and treating complex conditions like hypophosphatemic osteomalacia, particularly when associated with autoimmune disorders like Sjogren's syndrome. It underscores the importance of considering various factors and the potential interplay of treatments in managing such cases.
9
Impact of Vitamin D on Chest Pain
We observed a case involving a middle-aged woman who reported persistent chest pain after starting a new weight training routine. Initially, her pain was localized around the right chest area, making it hard to pinpoint the exact cause. Standard examinations, including ultrasound and X-rays, didn’t uncover any issues, leading to further investigation with an MRI.

The MRI revealed swelling in the sternum, indicating a sternal stress fracture. In response to this finding, the patient was prescribed calcium and vitamin D supplements and advised to rest for six weeks. Following her recovery period, she gradually resumed her activities and was pleased to find herself pain-free after four months.

While it’s clear that vitamin D was part of her treatment regimen, we can only speculate on its specific role in alleviating her chest pain because it was combined with calcium. This means we can't definitively state that vitamin D alone was effective in this case.

Overall, this case serves as an interesting insight into the management of stress fractures in the chest area, showing the importance of proper supplementation and rest in recovery.
We investigated how vitamin D influences chest pain in individuals experiencing vaccine-related myocarditis after receiving the BNT162b2 COVID-19 vaccine. Our study involved analyzing vitamin D levels, immune profiles, and genetic factors in 60 patients who suffered from this condition.

A significant finding was that a high percentage of these patients, about 73.3%, were found to have low vitamin D levels. Particularly concerning was the observation that those patients who presented with chest pain were more likely to be vitamin D deficient. We also found that lower vitamin D levels were linked to higher peak levels of cardiac troponin T, a marker indicating heart stress.

Additionally, we explored genetic factors and found that certain genetic variations could either increase or increase the potential risk related to vitamin D status. These findings suggest that hypovitaminosis D may exacerbate inflammation and activate specific immune cells, leading to symptoms like chest pain.

Overall, our research supports the idea that improving vitamin D status could be crucial in reducing vaccine-related myocarditis and associated chest pain, revealing a path for potential preventive measures and treatment strategies.
8
Vitamin D deficiency affects symptoms
We aimed to understand how vitamin D deficiency (VDD) might influence symptoms like chest pain, anxiety, and fatigue in people living with coronary artery disease (CAD). In our investigation, we collected data from 90 CAD patients, focusing on their vitamin D levels and experiences with these symptoms.

The findings were quite revealing. A significant 80% of the participants were found to have low vitamin D levels. Interestingly, we discovered that lower vitamin D levels were linked to increased chest pain and heightened anxiety and fatigue. Specifically, there were strong negative relationships noted: as vitamin D levels dropped, chest pain, anxiety, and fatigue scores rose.

This suggests that addressing vitamin D deficiency might be an important step for managing cardiac-related symptoms in patients with CAD. As this connection unfolds, it seems valuable for healthcare providers to monitor vitamin D levels in CAD patients and consider interventions to correct deficiencies.
8
Vitamin D3's Heart Impact
We explored how vitamin D3 plays a role in managing chest pain, particularly in relation to various cardiovascular health indicators. Our investigation emphasizes the significance of optimal vitamin D3 dosage; notably, 400 IU proves beneficial for heart health. However, we also highlighted the potential risks associated with higher doses, such as the commonly used 2000 IU, which can be detrimental.

While vitamin D3 shows promise for overall wellness, its direct impact on alleviating chest pain remains less clear. The study examines visible and invisible changes on the face that suggest cardiovascular issues, with a focus on areas like the eyebrows and left upper lip. However, there’s no conclusive evidence to suggest a marked improvement in chest pain solely from vitamin D3 treatment.

Overall, while maintaining adequate vitamin D3 levels is crucial for heart health, relying on it exclusively to relieve chest pain doesn't seem fully supported by our findings. The emphasis is on a comprehensive approach, combining dietary supplements with other medical interventions for heart conditions.

User Reviews

USERS' SCORE
Moderately Good
Based on 1 Review
7.7
  • All Reviews
  • Positive Reviews
  • Negative Reviews
0
Severe side effects
I purchased this to aid a fracture, but it caused my heart to race, worsened nocturia, and induced sudden chest pain in the fractured area along with pain throughout my body and joint noises. Initially unsure of the cause, I identified this supplement as the culprit. I question the inclusion of deep sea fish and whether it underwent radiation testing, as the quality seems poor. I’ve taken D3 from other brands without such symptoms, despite this low dosage leading to ridiculous side effects.

Frequently Asked Questions

No FAQs are available for this product and symptom.

References

  1. Tsang HW, Chua GT, Tung KTS, Wong RSM, Tsao SSL, et al. The protective role of vitamin D in BNT162b2 vaccine-related acute myocarditis. Front Immunol. 2025;16:1501609. doi:10.3389/fimmu.2025.1501609
  2. Khater WA, Alfarkh MA, Allnoubani A. The Association Between Vitamin D Level and Chest Pain, Anxiety, and Fatigue in Patients With Coronary Artery Disease. Clin Nurs Res. 2023;32:639. doi:10.1177/10547738221126325
  3. Alkhatatbeh MJ, Abdul-Razzak KK, Amara NA, Al-Jarrah M. Non-cardiac Chest Pain and Anxiety: A Possible Link to Vitamin D and Calcium. J Clin Psychol Med Settings. 2019;26:194. doi:10.1007/s10880-018-9579-2
  4. Tsuchiya M, Takaki R, Kobayashi F, Nagasaka T, Shindo K, et al. [Multiple pseudofractures due to Fanconi's syndrome associated with Wilson's disease]. Rinsho Shinkeigaku. 2017;57:527. doi:10.5692/clinicalneurol.cn-000953
  5. Shen G, Zhang Y, Hu S, Liu B, Kuang A. Adult-onset hypophosphatemic osteomalacia associated with Sjogren syndrome: Clinical case report. Medicine (Baltimore). 2017;96:e6493. doi:10.1097/MD.0000000000006493
  6. Lee J, Fields KB. Sternal stress fracture in a middle-aged woman. BMJ Case Rep. 2017;2017. doi:10.1136/bcr-2016-218203
  7. Omura Y, Jones MK, Duvvi H, Shimotsuura Y, Ohki M, et al. Non-invasive quick diagnosis of cardiovascular problems from visible and invisible abnormal changes with increased cardiac troponin I appearing on cardiovascular representation areas of the eyebrows, left upper lip, etc. of the face & hands: beneficial manual stimulation of hands for acute anginal chest pain, and important factors in safe, effective treatment. Acupunct Electrother Res. 2014;39:135.
  8. Lehmann G, Deisenhofer I, Ndrepepa G, Schmitt C. ECG changes in a 25-year-old woman with hypocalcemia due to hypoparathyroidism. Hypocalcemia mimicking acute myocardial infarction. Chest. 2000;118:260.
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