We explored the effects of vitamin E supplementation on patients with Smith-Lemli-Opitz Syndrome (SLOS), particularly focusing on symptoms like eczema. In a three-year study, six patients who were already on dietary cholesterol treatment received vitamin E. Their vitamin E levels were initially low, but following supplementation, all patients showed a significant increase in plasma vitamin E concentrations.
Among the various symptoms assessed, including aggression, irritability, and skin issues like eczema, some patients reported improvements. Our findings indicated that three out of the six patients experienced a reduction in symptoms, including skin photosensitivity and eczema. Notably, those who responded best to therapy had lower baseline ratios of certain cholesterol-related compounds.
While the study suggests that vitamin E could provide benefits to SLOS patients—possibly contributing to improvements in skin conditions like eczema—individual responses varied. Thus, vitamin E supplementation may be worth considering in the management of SLOS, especially for those with low initial vitamin E levels and certain biochemical markers.
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Most Useful Reviews
9
Eczema healed
My eczema has completely disappeared, and my skin has improved significantly.
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7.5
Eczema improvement
I began taking Fujikawa Theory supplements to enhance my health and chose this Vitamin E after learning that mixed ingredient E is beneficial. Alongside Vitamin C, iron, Vitamin B, and protein, I had been plagued by eczema on my hands for years. Remarkably, after a month, my eczema has noticeably lessened, and my motivation to continue using the product has grown. Although the capsules are large, I found them easy to swallow.
We explored the effects of vitamin E supplementation on patients with Smith-Lemli-Opitz Syndrome (SLOS), particularly focusing on symptoms like eczema. In a three-year study, six patients who were already on dietary cholesterol treatment received vitamin E. Their vitamin E levels were initially low, but following supplementation, all patients showed a significant increase in plasma vitamin E concentrations.
Among the various symptoms assessed, including aggression, irritability, and skin issues like eczema, some patients reported improvements. Our findings indicated that three out of the six patients experienced a reduction in symptoms, including skin photosensitivity and eczema. Notably, those who responded best to therapy had lower baseline ratios of certain cholesterol-related compounds.
While the study suggests that vitamin E could provide benefits to SLOS patients—possibly contributing to improvements in skin conditions like eczema—individual responses varied. Thus, vitamin E supplementation may be worth considering in the management of SLOS, especially for those with low initial vitamin E levels and certain biochemical markers.
Read More
User Reviews
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Based on 2 Reviews
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Negative Reviews
9
Eczema healed
My eczema has completely disappeared, and my skin has improved significantly.
Read More
7.5
Eczema improvement
I began taking Fujikawa Theory supplements to enhance my health and chose this Vitamin E after learning that mixed ingredient E is beneficial. Alongside Vitamin C, iron, Vitamin B, and protein, I had been plagued by eczema on my hands for years. Remarkably, after a month, my eczema has noticeably lessened, and my motivation to continue using the product has grown. Although the capsules are large, I found them easy to swallow.
Read More
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References
Koczok K, Horváth L, Korade Z, Mezei ZA, Szabó GP, et al. Biochemical and Clinical Effects of Vitamin E Supplementation in Hungarian Smith-Lemli-Opitz Syndrome Patients. Biomolecules. 2021;11. 10.3390/biom11081228