Selenium Supplementation and the Effects on Reproductive Outcomes, Biomarkers of Inflammation, and Oxidative Stress in Women with Polycystic Ovary Syndrome.
We conducted a randomized double-blind, placebo-controlled trial to explore how selenium supplementation may influence hair loss among women with polycystic ovary syndrome (PCOS). In the study, 64 women aged 18-40 received either 200 μg of selenium daily or a placebo for eight weeks.
After the treatment period, we noticed a significant improvement in hair-related issues for those taking selenium. Specifically, alopecia rates dropped from 40.6% in the selenium group to just 9.4% in the placebo group, showing a strong positive effect of the supplement on hair loss. Acne also improved, with a reduction from 46.9% to 12.5%.
Furthermore, women who took selenium supplements exhibited decreased levels of dehydroepiandrosterone (DHEA), hirsutism, and markers of inflammation and oxidative stress. However, it’s important to note that selenium did not show significant effects on some hormonal profiles and other biomarkers. Overall, our findings suggest that selenium can be beneficial for women with PCOS, particularly regarding hair loss and related symptoms.
We explored a novel approach to treat androgenetic alopecia (AGA) using microneedles that deliver selenium nanoparticles. The study designed a biocomposite patch to improve the environment around hair follicles by enhancing blood flow and reducing inflammation.
When tested on mice, this microneedle system showed promise in boosting hair density and enlarging hair follicles. However, while the results are encouraging, further research is needed to confirm its effectiveness in humans.
Read More
8
Selenium supplementation may help hair loss
Selenium as an element in the treatment of ovarian cancer in women receiving chemotherapy.
We examined how selenium supplementation influences hair loss in women undergoing chemotherapy for ovarian cancer. This study involved 31 patients who received 200 micrograms of selenium daily.
Over three months, we noticed significant improvements: hair loss decreased, alongside reductions in discomfort and fatigue. While selenium levels in patients' hair didn't increase markedly after the first month, serum levels rose significantly.
Ultimately, selenium appears beneficial as a supportive treatment in managing hair loss during chemotherapy.
Read More
Most Useful Reviews
9
Reduced hair loss
2 people found this helpful
Excellent product. Very high quality. It has made a significant difference in reducing hair loss and normalising thyroid hormones. Definitely recommend!
Read More
7.5
Reduced hair loss
1 people found this helpful
Since starting selenium, my health has improved significantly. My sleep returned to normal, I wake up on time, and my thinking has become clearer, with fewer headaches. The condition of my facial skin has also improved, with small pimples disappearing. I noticed the positive effects almost immediately, including much less hair loss in the shower. For anyone facing this issue, I recommend trying it, as I experienced no side effects.
Read More
9
Hair restoration success
Selenium has become an essential part of my daily routine. Two years ago, I struggled with severe hair loss due to Hashimoto's thyroid condition. After researching, I decided to incorporate certain nutrients, including selenium. Over these two years, my hair loss condition has significantly improved, and I am thrilled to say that I have got my hair back!
We explored a novel approach to treat androgenetic alopecia (AGA) using microneedles that deliver selenium nanoparticles. The study designed a biocomposite patch to improve the environment around hair follicles by enhancing blood flow and reducing inflammation.
When tested on mice, this microneedle system showed promise in boosting hair density and enlarging hair follicles. However, while the results are encouraging, further research is needed to confirm its effectiveness in humans.
Read More
8
Selenium may aid hair loss treatments
Efficacy and tolerability of an oral supplement containing amino acids, iron, selenium, and marine hydrolyzed collagen in subjects with hair loss (androgenetic alopecia, AGA or FAGA or telogen effluvium). A prospective, randomized, 3-month, controlled, assessor-blinded study.
We conducted a thorough investigation into the effectiveness of a novel oral supplement containing selenium, among other ingredients, in addressing hair loss conditions like androgenetic alopecia (AGA) and telogen effluvium (TE). Our study involved 83 participants who were divided into two groups: one received the supplement alongside their prescribed treatments, while the other received only the treatments.
Over 12 weeks, we assessed the outcomes primarily through a global assessment score to see how much improvement, if any, participants experienced. Interestingly, we found that the supplement—rich in selenium, amino acids, and hydrolyzed collagen—enhanced the results for those undergoing anti-hair loss therapies.
In essence, the inclusion of selenium in this combination supplement appears to positively influence the effectiveness of standard treatments for hair loss. While our study was promising, it’s worth noting that deriving individual results for selenium alone is complicated since it was combined with other beneficial components.
Read More
8
Selenium aids hair loss in PCOS
Selenium Supplementation and the Effects on Reproductive Outcomes, Biomarkers of Inflammation, and Oxidative Stress in Women with Polycystic Ovary Syndrome.
We conducted a randomized double-blind, placebo-controlled trial to explore how selenium supplementation may influence hair loss among women with polycystic ovary syndrome (PCOS). In the study, 64 women aged 18-40 received either 200 μg of selenium daily or a placebo for eight weeks.
After the treatment period, we noticed a significant improvement in hair-related issues for those taking selenium. Specifically, alopecia rates dropped from 40.6% in the selenium group to just 9.4% in the placebo group, showing a strong positive effect of the supplement on hair loss. Acne also improved, with a reduction from 46.9% to 12.5%.
Furthermore, women who took selenium supplements exhibited decreased levels of dehydroepiandrosterone (DHEA), hirsutism, and markers of inflammation and oxidative stress. However, it’s important to note that selenium did not show significant effects on some hormonal profiles and other biomarkers. Overall, our findings suggest that selenium can be beneficial for women with PCOS, particularly regarding hair loss and related symptoms.
Read More
8
Selenium supplementation may help hair loss
Selenium as an element in the treatment of ovarian cancer in women receiving chemotherapy.
We examined how selenium supplementation influences hair loss in women undergoing chemotherapy for ovarian cancer. This study involved 31 patients who received 200 micrograms of selenium daily.
Over three months, we noticed significant improvements: hair loss decreased, alongside reductions in discomfort and fatigue. While selenium levels in patients' hair didn't increase markedly after the first month, serum levels rose significantly.
Ultimately, selenium appears beneficial as a supportive treatment in managing hair loss during chemotherapy.
Read More
User Reviews
USERS' SCORE
Medium or Average
Based on 6 Reviews
6.1
All Reviews
Positive Reviews
Negative Reviews
9
Reduced hair loss
2 people found this helpful
Excellent product. Very high quality. It has made a significant difference in reducing hair loss and normalising thyroid hormones. Definitely recommend!
Read More
7.5
Reduced hair loss
1 people found this helpful
Since starting selenium, my health has improved significantly. My sleep returned to normal, I wake up on time, and my thinking has become clearer, with fewer headaches. The condition of my facial skin has also improved, with small pimples disappearing. I noticed the positive effects almost immediately, including much less hair loss in the shower. For anyone facing this issue, I recommend trying it, as I experienced no side effects.
Read More
9
Hair restoration success
Selenium has become an essential part of my daily routine. Two years ago, I struggled with severe hair loss due to Hashimoto's thyroid condition. After researching, I decided to incorporate certain nutrients, including selenium. Over these two years, my hair loss condition has significantly improved, and I am thrilled to say that I have got my hair back!
Read More
0
Hair loss experienced
62 people found this helpful
I wanted to improve my hair, after reading positive comments about its effects. However, I fell ill beneath my left rib after starting selenium. Although I took only one supplement daily for a couple of weeks, I observed that my hair began to fall out. A laboratory analysis confirmed an overdose of selenium in my body. After stopping the supplement, the pain subsided. So, it's crucial to take tests before starting any supplements. Instead of achieving hair growth, I ended up with hair loss.
Read More
7.5
Long-term aid for hair loss
If you have hypothyroidism, selenium is essential for lifelong daily use, around 200 days. I find it economical and effective. I usually source it from the pharmacy, and this option is less expensive. It has a significant effect on hair loss, especially when combined with zinc.
Hair loss, also known as alopecia, is a common condition that affects both men and women, characterized by the thinning or complete loss of hair from the scalp or other areas of the body. It can occur due to various factors, including genetics, hormonal changes, medical conditions, and environmental factors. The most prevalent type of hair loss is androgenetic alopecia, often referred to as male or female pattern baldness, which typically results in a receding hairline or thinning crown in men and overall thinning in women.
In addition to genetic predisposition, hair loss can be triggered by stress, poor diet, certain medications, and underlying health issues such as thyroid disorders or autoimmune diseases. There are various treatment options available, ranging from over-the-counter products like minoxidil to prescription medications and hair restoration procedures, depending on the severity and cause of hair loss. It's crucial to consult with a healthcare professional to determine the most appropriate treatment plan tailored to individual needs and conditions.
Selenium is a powerful and widely used open-source tool designed for automating web applications for testing purposes. It enables developers and testers to write code in various programming languages such as Java, Python, C#, and Ruby to simulate user interactions with a web browser. Selenium's flexibility allows users to create complex test scenarios that mimic real-world user behaviors, making it an essential tool for ensuring web application functionality and performance.
In addition to its core functionalities, Selenium consists of several components, including Selenium WebDriver for automating browsers, Selenium Grid for running tests across multiple machines and environments in parallel, and Selenium IDE for record-and-playback test creation. Its compatibility with multiple browser types—such as Chrome, Firefox, Safari, and Edge—makes it a versatile choice for automated testing, catering to a wide range of projects and team needs. For anyone involved in web development or quality assurance, understanding and utilizing Selenium can significantly improve testing efficiency and reliability.
Based on user reviews, the timeline for seeing results from taking selenium supplements for hair loss can vary significantly. Some users report noticing improvements almost immediately, with one individual stating they experienced much less hair loss in the shower shortly after starting the supplement Read Review. Meanwhile, others, particularly those with specific health conditions like Hashimoto's thyroid disease, suggest a longer commitment may be necessary, with one user noting significant improvements occurring over a span of two years Read Review.
However, it's important to note that some users cautioned against potential negative side effects such as a selenium overdose and associated hair loss when not monitored correctly Read Review. While some may see changes within weeks, others advocate for a sustained regimen of several months to a year, especially when combined with other supplements like zinc for the best results Read Review. Overall, the consensus seems to indicate that results can take time, but individual experiences may vary widely.
Numerous studies have investigated the potential of selenium as a supplement for treating hair loss, yielding promising results. One notable research project involved 64 women with polycystic ovary syndrome (PCOS) who demonstrated significant improvement in hair-related issues with selenium supplementation. The participants saw alopecia rates drop dramatically from 40.6% in the selenium group to just 9.4% in the placebo group, indicating a strong positive effect of selenium on hair loss specifically related to this condition [2]. Additionally, selenium has been shown to enhance the outcomes of standard hair loss treatments when included in a combination supplement along with other beneficial ingredients, thereby indicating its potential efficacy in broader applications [1].
Further research also highlights selenium's benefits in unique contexts, such as during chemotherapy for ovarian cancer, where supplementation demonstrated reductions in hair loss and associated discomfort [4]. However, while results from studies utilizing selenium nanoparticles in microneedles show promise, further research is essential to determine their effectiveness in human subjects [3]. Overall, these findings suggest that selenium may be a worthwhile consideration for those experiencing hair loss, particularly in specific conditions like PCOS and during chemotherapy.
Users have reported a range of improvements after incorporating selenium into their routines, with many noting significant enhancements in both cognitive function and skin condition, along with reductions in hair loss. One user highlighted immediate benefits, mentioning clearer thinking, improved sleep patterns, and a noticeable decrease in hair loss while showering shortly after starting the supplement Read Review. Another user with Hashimoto's thyroid condition shared that after two years of daily selenium use, their severe hair loss had drastically improved, and they regained their hair, showcasing how long-term use can yield substantial positive results Read Review.
Conversely, it’s important to approach selenium supplementation with caution, as some users experienced adverse effects, including hair loss, likely related to an overdose. One individual reported developing pain and hair loss shortly after beginning supplementation, only to discover through lab testing that their selenium levels were too high Read Review. This emphasizes the necessity of monitoring selenium intake and considering health conditions before beginning supplementation. Overall, anecdotal experiences suggest the potential for beneficial outcomes, though results can vary significantly between individuals.
Users report a mixed bag of experiences when combining selenium with other supplements for handling hair loss. One user found significant improvements in their hair loss condition, specifically noting that pairing selenium with zinc proved impactful Read Review. This indicates that a combination of these supplements may enhance their effectiveness, particularly for individuals facing conditions like hypothyroidism. Others echoed similar sentiments, suggesting that incorporating selenium alongside other nutrients can optimize results in combating hair loss.
However, caution is also a recurring theme in the reviews, as some individuals experienced negative side effects, such as pain and actual hair loss attributed to selenium overdose Read Review. Users stressed the importance of monitoring intake and encouraging laboratory tests before beginning supplementation to prevent adverse effects. This highlights the need for personalized approaches when considering selenium, particularly in tandem with other supplements, as experiences can greatly vary among users.
The optimal dosage of selenium for treating hair loss, particularly in certain populations, seems to be around 200 micrograms (μg) per day. This was demonstrated in a randomized double-blind, placebo-controlled trial involving women aged 18-40 with polycystic ovary syndrome (PCOS), where participants taking 200 μg of selenium daily experienced a significant reduction in alopecia rates from 40.6% to just 9.4% when compared to the placebo group [2]. Additionally, another study focusing on women undergoing chemotherapy for ovarian cancer utilized the same dosage of 200 μg of selenium daily and reported significant improvements in hair loss and related discomfort [4].
While these findings highlight the potential benefits of selenium supplementation at this dosage, it's crucial to note that results may vary based on individual circumstances and the specific type of hair loss being treated. Therefore, consulting with a healthcare professional before starting any supplement regimen is always advisable to ensure safety and efficacy.
7.5
Reduced hair loss
1 people found this helpful
Since starting selenium, my health has improved significantly. My sleep returned to normal, I wake up on time, and my thinking has become clearer, with fewer headaches. The condition of my facial skin has also improved, with small pimples disappearing. I noticed the positive effects almost immediately, including much less hair loss in the shower. For anyone facing this issue, I recommend trying it, as I experienced no side effects.
9
Hair restoration success
Selenium has become an essential part of my daily routine. Two years ago, I struggled with severe hair loss due to Hashimoto's thyroid condition. After researching, I decided to incorporate certain nutrients, including selenium. Over these two years, my hair loss condition has significantly improved, and I am thrilled to say that I have got my hair back!
0
Hair loss experienced
62 people found this helpful
I wanted to improve my hair, after reading positive comments about its effects. However, I fell ill beneath my left rib after starting selenium. Although I took only one supplement daily for a couple of weeks, I observed that my hair began to fall out. A laboratory analysis confirmed an overdose of selenium in my body. After stopping the supplement, the pain subsided. So, it's crucial to take tests before starting any supplements. Instead of achieving hair growth, I ended up with hair loss.
7.5
Long-term aid for hair loss
If you have hypothyroidism, selenium is essential for lifelong daily use, around 200 days. I find it economical and effective. I usually source it from the pharmacy, and this option is less expensive. It has a significant effect on hair loss, especially when combined with zinc.
8
Selenium aids hair loss in PCOS
Selenium Supplementation and the Effects on Reproductive Outcomes, Biomarkers of Inflammation, and Oxidative Stress in Women with Polycystic Ovary Syndrome.
We conducted a randomized double-blind, placebo-controlled trial to explore how selenium supplementation may influence hair loss among women with polycystic ovary syndrome (PCOS). In the study, 64 women aged 18-40 received either 200 μg of selenium daily or a placebo for eight weeks.
After the treatment period, we noticed a significant improvement in hair-related issues for those taking selenium. Specifically, alopecia rates dropped from 40.6% in the selenium group to just 9.4% in the placebo group, showing a strong positive effect of the supplement on hair loss. Acne also improved, with a reduction from 46.9% to 12.5%.
Furthermore, women who took selenium supplements exhibited decreased levels of dehydroepiandrosterone (DHEA), hirsutism, and markers of inflammation and oxidative stress. However, it’s important to note that selenium did not show significant effects on some hormonal profiles and other biomarkers. Overall, our findings suggest that selenium can be beneficial for women with PCOS, particularly regarding hair loss and related symptoms.
8
Selenium may aid hair loss treatments
Efficacy and tolerability of an oral supplement containing amino acids, iron, selenium, and marine hydrolyzed collagen in subjects with hair loss (androgenetic alopecia, AGA or FAGA or telogen effluvium). A prospective, randomized, 3-month, controlled, assessor-blinded study.
We conducted a thorough investigation into the effectiveness of a novel oral supplement containing selenium, among other ingredients, in addressing hair loss conditions like androgenetic alopecia (AGA) and telogen effluvium (TE). Our study involved 83 participants who were divided into two groups: one received the supplement alongside their prescribed treatments, while the other received only the treatments.
Over 12 weeks, we assessed the outcomes primarily through a global assessment score to see how much improvement, if any, participants experienced. Interestingly, we found that the supplement—rich in selenium, amino acids, and hydrolyzed collagen—enhanced the results for those undergoing anti-hair loss therapies.
In essence, the inclusion of selenium in this combination supplement appears to positively influence the effectiveness of standard treatments for hair loss. While our study was promising, it’s worth noting that deriving individual results for selenium alone is complicated since it was combined with other beneficial components.
8
Selenium supplementation may help hair loss
Selenium as an element in the treatment of ovarian cancer in women receiving chemotherapy.
We examined how selenium supplementation influences hair loss in women undergoing chemotherapy for ovarian cancer. This study involved 31 patients who received 200 micrograms of selenium daily.
Over three months, we noticed significant improvements: hair loss decreased, alongside reductions in discomfort and fatigue. While selenium levels in patients' hair didn't increase markedly after the first month, serum levels rose significantly.
Ultimately, selenium appears beneficial as a supportive treatment in managing hair loss during chemotherapy.
We explored a novel approach to treat androgenetic alopecia (AGA) using microneedles that deliver selenium nanoparticles. The study designed a biocomposite patch to improve the environment around hair follicles by enhancing blood flow and reducing inflammation.
When tested on mice, this microneedle system showed promise in boosting hair density and enlarging hair follicles. However, while the results are encouraging, further research is needed to confirm its effectiveness in humans.
References
Milani M, Colombo F. Efficacy and tolerability of an oral supplement containing amino acids, iron, selenium, and marine hydrolyzed collagen in subjects with hair loss (androgenetic alopecia, AGA or FAGA or telogen effluvium). A prospective, randomized, 3-month, controlled, assessor-blinded study. Skin Res Technol. 2023;29:e13381. 10.1111/srt.13381
Razavi M, Jamilian M, Kashan ZF, Heidar Z, Mohseni M, et al. Selenium Supplementation and the Effects on Reproductive Outcomes, Biomarkers of Inflammation, and Oxidative Stress in Women with Polycystic Ovary Syndrome. Horm Metab Res. 2016;48:185. 10.1055/s-0035-1559604
Jing S, Liu Y, Wang B, Zhou H, Zhang H, et al. Microneedle-mediated hypoxic extracellular vesicle-encapsulated selenium nanoparticles delivery to treat androgenetic alopecia. J Control Release. 2025;381:113597. 10.1016/j.jconrel.2025.113597
Sieja K, Talerczyk M. Selenium as an element in the treatment of ovarian cancer in women receiving chemotherapy. Gynecol Oncol. 2004;93:320.