We examined the potential of a multimodal therapy approach for treating chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) using the UPOINTS phenotyping system. Involving 914 patients, the study combined α-blockers, supplements like selenium, and antibacterial agents among others.
After a six-month course, we noted significant improvements in symptoms, with 77.5% of patients achieving a meaningful reduction in their pain scores. Notably, patients with the inflammatory subtype showed marked symptom relief compared to the non-inflammatory group. This suggests a tailored approach could effectively address the complexities of CP/CPPS.
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Selenium enhances pelvic pain treatmentTreatment of chronic prostatitis/chronic pelvic pain syndrome category IIIA with Serenoa repens plus selenium and lycopene (Profluss) versus S. repens alone: an Italian randomized multicenter-controlled study.
High relevance for treatment modalities
We evaluated the effects of a treatment combining Serenoa repens with selenium and lycopene, known as Profluss, against Serenoa repens alone for chronic pelvic pain in 102 men. After an 8-week period, both groups experienced symptom improvements. However, the Profluss group showed a significantly greater reduction in pelvic pain scores and additional benefits in other measures, suggesting that selenium can enhance treatment effectiveness for this condition.
While both treatments offered relief, Profluss was particularly beneficial. This finding indicates that adding selenium to standard therapy might be advantageous in managing pelvic pain.
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Selenium boosts antioxidant status[The possibility of correcting oxidative stress in patients with inflammatory type of chronic abacterial prostatitis (chronic pelvic pain syndrome category IIIa)].
Moderate relevance to chronic pain
We sought to understand how a mineral-vitamin complex, specifically Selzinc-plus, may help treat chronic abacterial prostatitis, a condition often linked with pelvic pain. In a study involving 47 men, we divided them into two groups: one received standard therapy, and the other received additional Selzinc-plus for two months.
While standard therapy showed effects, the antioxidant treatment significantly enhanced these benefits on symptoms. Notably, though the overall antioxidant system improved, no significant changes were observed in leukocyte counts. Our findings suggest that this antioxidant approach may offer added relief for those suffering from pelvic pain.
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We focused on the effects of a dietary supplement combining several natural ingredients, including selenium, on chronic pelvic pain in men with Category IIIA prostatitis.
Patients taking this supplement showed significant reductions in inflammation and pain, as evidenced by lower white blood cell counts in seminal fluid and improved pain scores.
These findings suggest that selenium, along with other nutrients, may play a beneficial role in alleviating pelvic pain associated with chronic prostatitis.
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