Dietary zinc status is associated with ZnT3 (SLC30A3), IL-6 gene expressions and spinal cord tissue damage in spinal cord tissue in a cuprizone-induced rat Multiple Sclerosis model.
We explored how dietary zinc levels influence spinal cord damage and gene expressions associated with Multiple Sclerosis (MS) using a cuprizone-induced rat model. The study included 46 adult male Wistar rats divided into five groups, with some receiving zinc supplementation while others followed a zinc-deficient diet.
After eight weeks of treatment, we found that the rats with MS symptoms showed elevated markers of tissue damage and inflammation, particularly in the groups that lacked zinc. Notably, those receiving zinc supplementation exhibited significantly reduced levels of harmful substances, bringing them back closer to control levels.
Our findings highlight zinc's protective effects in a model of MS, suggesting that incorporating zinc into treatment plans could help alleviate some symptoms associated with this autoimmune disorder. This is promising for future treatment strategies for those affected by MS.
Read More
9
Zinc intake benefits RA bone health
The association between dietary zinc intake and osteopenia, osteoporosis in patients with rheumatoid arthritis.
We aimed to understand how dietary zinc intake influences the risk of developing osteopenia and osteoporosis in patients with rheumatoid arthritis (RA). Our study relied on data collected from the National Health and Nutrition Examination Survey, spanning several years. Through careful analysis using univariate and multivariate logistic regression models, we were able to uncover significant associations between dietary zinc levels and bone health in this population.
What we found was encouraging: higher zinc intake appeared to lower the chances of these serious bone conditions among RA patients. Our research also went further by examining various factors such as age, body mass index (BMI), and pre-existing health issues like diabetes and hypertension. This comprehensive approach led us to conclude that adequate dietary zinc is crucial for maintaining bone health in individuals with RA, though we noted the need for more extensive long-term studies to corroborate these findings and delve deeper into the underlying mechanisms at play.
Read More
8
Zinc transport's role in T cells
SLC39A10 is a key zinc transporter in T cells and its loss mitigates autoimmune disease.
We identified an important link between zinc transport and autoimmune disorders, specifically focusing on the protein SLC39A10 and its role in T cells. Through our study, we discovered that two specific genetic variations in the SLC39A10 gene are associated with inflammatory bowel disease (IBD). To further explore this connection, we created genetically modified mice with a targeted deletion of the Slc39a10 gene in T cells.
Our findings revealed that the loss of SLC39A10 significantly protects against the progression of both IBD and experimental autoimmune encephalomyelitis (EAE). Notably, we also observed that the absence of this transporter led to increased cell death, independent of common pathways usually associated with apoptosis. This indicates that SLC39A10 plays a crucial role in maintaining the health of T cells by facilitating zinc import, which is essential for DNA replication when T cells are activated.
Our research contributes to a deeper understanding of how zinc homeostasis impacts immune function. The insights gained from this study suggest that targeting zinc transport could present new therapeutic options for managing T cell-related autoimmune diseases.
Read More
Most Useful Reviews
9
Significant energy boost
256 people found this helpful
Many thanks to iHerb for the swift delivery and dependable packaging. Solgar's vitamins have truly transformed my health. I used to suffer from frequent colds and felt constantly fatigued, but after taking these vitamins, my energy levels soared, my complexion improved, and I’ve found it easier to manage my autoimmune disorder. My routine includes potassium, magnesium, a B-complex, and zinc in the evening.
Read More
9
Reduced skin rashes
80 people found this helpful
I purchased zinc to combat skin rashes as advised by my doctor since it helps with acne and other skin concerns. After two months of consistent use, I've seen fewer rashes and improved skin elasticity. There were no gastrointestinal issues or allergies, and my hair and nails also appeared healthier. I will continue to buy Solgar zinc.
Read More
9
Family health booster
16 people found this helpful
I consistently order for my family. We appreciate the vitamin's form, size, and effects: clearer skin, improved hair, and better immunity. In spring and autumn, we take one daily. I shared it with a neighbour, and he quickly recovered from a cold. An excellent addition to our health!
Dietary zinc status is associated with ZnT3 (SLC30A3), IL-6 gene expressions and spinal cord tissue damage in spinal cord tissue in a cuprizone-induced rat Multiple Sclerosis model.
We explored how dietary zinc levels influence spinal cord damage and gene expressions associated with Multiple Sclerosis (MS) using a cuprizone-induced rat model. The study included 46 adult male Wistar rats divided into five groups, with some receiving zinc supplementation while others followed a zinc-deficient diet.
After eight weeks of treatment, we found that the rats with MS symptoms showed elevated markers of tissue damage and inflammation, particularly in the groups that lacked zinc. Notably, those receiving zinc supplementation exhibited significantly reduced levels of harmful substances, bringing them back closer to control levels.
Our findings highlight zinc's protective effects in a model of MS, suggesting that incorporating zinc into treatment plans could help alleviate some symptoms associated with this autoimmune disorder. This is promising for future treatment strategies for those affected by MS.
Read More
9
Zinc intake benefits RA bone health
The association between dietary zinc intake and osteopenia, osteoporosis in patients with rheumatoid arthritis.
We aimed to understand how dietary zinc intake influences the risk of developing osteopenia and osteoporosis in patients with rheumatoid arthritis (RA). Our study relied on data collected from the National Health and Nutrition Examination Survey, spanning several years. Through careful analysis using univariate and multivariate logistic regression models, we were able to uncover significant associations between dietary zinc levels and bone health in this population.
What we found was encouraging: higher zinc intake appeared to lower the chances of these serious bone conditions among RA patients. Our research also went further by examining various factors such as age, body mass index (BMI), and pre-existing health issues like diabetes and hypertension. This comprehensive approach led us to conclude that adequate dietary zinc is crucial for maintaining bone health in individuals with RA, though we noted the need for more extensive long-term studies to corroborate these findings and delve deeper into the underlying mechanisms at play.
Read More
8
Zinc transport's role in T cells
SLC39A10 is a key zinc transporter in T cells and its loss mitigates autoimmune disease.
We identified an important link between zinc transport and autoimmune disorders, specifically focusing on the protein SLC39A10 and its role in T cells. Through our study, we discovered that two specific genetic variations in the SLC39A10 gene are associated with inflammatory bowel disease (IBD). To further explore this connection, we created genetically modified mice with a targeted deletion of the Slc39a10 gene in T cells.
Our findings revealed that the loss of SLC39A10 significantly protects against the progression of both IBD and experimental autoimmune encephalomyelitis (EAE). Notably, we also observed that the absence of this transporter led to increased cell death, independent of common pathways usually associated with apoptosis. This indicates that SLC39A10 plays a crucial role in maintaining the health of T cells by facilitating zinc import, which is essential for DNA replication when T cells are activated.
Our research contributes to a deeper understanding of how zinc homeostasis impacts immune function. The insights gained from this study suggest that targeting zinc transport could present new therapeutic options for managing T cell-related autoimmune diseases.
Read More
8
Zinc's role in alopecia areata
Association Between Serum Trace Elements Level and Alopecia Areata: A Systematic Review and Meta-Analysis.
We analyzed how zinc levels in the body relate to alopecia areata (AA), an autoimmune disorder that affects hair loss. Our research involved a systematic review of 34 studies, gathering data from nearly 5,000 participants across 16 countries. By examining various studies, we sought to understand if zinc supplementation could be beneficial for those suffering from AA.
The results were striking. We found that individuals with alopecia areata had significantly lower levels of zinc and vitamin D compared to healthy individuals. Specifically, the data indicated that those with vitamin D deficiency faced a heightened risk of developing AA. This suggests that replenishing these nutrients might help manage the disease.
Importantly, we didn't find a significant difference in copper levels between AA patients and healthy controls, indicating that not all trace elements play the same role in this condition. Overall, our findings highlight the potential of zinc and vitamin D as targeted treatments for alopecia areata, offering new hope for those affected by this condition.
Read More
7
Zinc supplementation eases neutrophil activity
Zinc Supplementation Reduces the Formation of Neutrophil Extracellular Traps by Decreasing the Expression of Peptidyl Arginine Deiminase 4.
We aimed to explore how zinc supplementation might influence immune responses, particularly focusing on neutrophil activity in the context of autoimmune diseases. To do this, we simulated inflammatory conditions typically seen in such disorders using specific cytokines, interleukin-17 (IL-17) and tumor necrosis factor (TNF)-α.
Our findings indicated that elevating zinc levels significantly reduced the formation of neutrophil extracellular traps (NETs), which are often implicated in tissue damage during autoimmune flare-ups. We also discovered that zinc supplementation lowered the expression of a protein called peptidyl arginine deiminase 4 (PAD4), which is associated with NET formation.
Interestingly, zinc not only decreased harmful neutrophil activity but also boosted the production of beneficial proteins like interleukin-1 receptor antagonist (IL-1RA) and IL-8 in the activated cells. Overall, maintaining adequate zinc levels seems crucial for preserving healthy immune function and preventing the harmful overactivity of neutrophils, suggesting its potential as an adjunct treatment in managing autoimmune conditions.
Many thanks to iHerb for the swift delivery and dependable packaging. Solgar's vitamins have truly transformed my health. I used to suffer from frequent colds and felt constantly fatigued, but after taking these vitamins, my energy levels soared, my complexion improved, and I’ve found it easier to manage my autoimmune disorder. My routine includes potassium, magnesium, a B-complex, and zinc in the evening.
Read More
9
Reduced skin rashes
80 people found this helpful
I purchased zinc to combat skin rashes as advised by my doctor since it helps with acne and other skin concerns. After two months of consistent use, I've seen fewer rashes and improved skin elasticity. There were no gastrointestinal issues or allergies, and my hair and nails also appeared healthier. I will continue to buy Solgar zinc.
Read More
9
Family health booster
16 people found this helpful
I consistently order for my family. We appreciate the vitamin's form, size, and effects: clearer skin, improved hair, and better immunity. In spring and autumn, we take one daily. I shared it with a neighbour, and he quickly recovered from a cold. An excellent addition to our health!
Read More
9
Acne reduction success
16 people found this helpful
My daughter used to suffer from facial breakouts, but ever since she started taking zinc, her acne has cleared up. Now, she insists I reorder as soon as possible whenever the symptoms return.
Read More
2
Pancreas reaction
10 people found this helpful
Zinc picolinate helped reduce my skin oiliness. However, it caused significant pancreatic reactions, leading to digestive issues despite its benefits for my autoimmune disorder. I had to stop taking it after trying a lower dosage.
An autoimmune disorder occurs when the body's immune system mistakenly attacks its own healthy cells and tissues, believing them to be foreign invaders, such as bacteria or viruses. This reaction can lead to inflammation, tissue damage, and impaired function of the affected organs. There are over 80 known autoimmune diseases, including rheumatoid arthritis, lupus, multiple sclerosis, and type 1 diabetes, each with its own specific symptoms and treatment options. The exact cause of these disorders is still unclear, but a combination of genetic, environmental, and hormonal factors is believed to play a role in their development.
Diagnosis of autoimmune disorders often involves a combination of physical examinations, assessment of symptoms, blood tests, and imaging studies to evaluate organ involvement. Treatment typically focuses on managing symptoms and controlling the immune response using medications such as corticosteroids, immunosuppressants, and biologics. In addition to medication, lifestyle modifications, such as stress management and a balanced diet, can be beneficial in managing symptoms. If you suspect you have an autoimmune condition, it's important to consult a healthcare professional for proper evaluation and tailored treatment options.
Zinc is a versatile metal known for its various applications in industry and health. It is a bluish-white metallic element represented by the symbol Zn and atomic number 30 on the periodic table. Zinc is primarily used for galvanizing steel to prevent rusting, in the manufacturing of alloys, and as a component in batteries. Additionally, zinc plays a crucial role in biological processes, making it an essential trace element in the human diet. It is involved in immune function, protein synthesis, wound healing, and DNA synthesis, highlighting its importance in maintaining overall health and well-being.
Zinc plays a crucial role in immune function and has been studied for its potential benefits in managing autoimmune disorders. This mineral is essential for the development and function of immune cells, and adequate levels may help modulate inflammatory responses. Some studies suggest that zinc supplementation may help reduce the severity of symptoms in certain autoimmune conditions, like rheumatoid arthritis and lupus, by influencing immune responses and reducing oxidative stress.
However, it's important to note that while zinc may offer supportive benefits, it should not be regarded as a standalone treatment for autoimmune disorders. The relationship between zinc and autoimmune diseases is complex; excessive zinc intake can also lead to adverse effects, including interference with other essential minerals. Therefore, anyone considering zinc supplementation, especially those with autoimmune disorders, should consult a healthcare provider for personalized advice and to determine the appropriate dosage. Keeping a balanced diet rich in nutrients, including zinc, can contribute to overall immune health.
Based on user reviews, the time it takes to notice results from taking zinc supplements for autoimmune disorders varies among individuals. Many users report experiencing benefits within one to six weeks of consistent use. For instance, one user noted a significant improvement in their rosacea severity after just six weeks of taking zinc picolinate daily Read Review. Another individual reported feeling a marked improvement in fatigue and low energy just one week into their regimen Read Review.
Some users emphasized that longer-term benefits emerged with continued use, highlighting improvements in skin health and immunity after a couple of months Read Review. However, there are instances where users experienced adverse effects or varying degrees of effectiveness, emphasizing that results can differ widely. In summary, while many individuals have reported positive results within a few weeks, consistent use over a longer period may be required to achieve the best outcomes in managing autoimmune disorders.
The research surrounding the efficacy of zinc supplementation in managing autoimmune disorders is increasingly compelling. For instance, a study demonstrated that zinc plays a vital role in T cell function, particularly through the SLC39A10 zinc transporter, which is critical for maintaining T cell health. Disruptions in this process can lead to conditions like inflammatory bowel disease and multiple sclerosis, suggesting that targeting zinc transport may offer new therapeutic routes for such autoimmune diseases [1]. Furthermore, other investigations have found that maintaining adequate zinc levels could alleviate symptoms in models of multiple sclerosis by reducing inflammation and tissue damage [4].
However, it’s essential to approach zinc supplementation with caution. Research indicates that excessive dietary zinc might adversely affect immune balance, increasing the risk of conditions like autoimmune thyroiditis. Thus, while supporting immune function through sufficient zinc intake may offer benefits, individuals should monitor their consumption to avoid potential complications [2]. Overall, zinc supplementation holds promise for managing various autoimmune disorders, with emerging studies advocating for its role in immune regulation and protection against autoimmune flare-ups [6].
Many users have reported notable improvements in various symptoms after incorporating zinc supplements into their routines. For those dealing with skin issues, such as acne and rashes, several users have mentioned significant enhancements in their conditions. One user observed a dramatic reduction in rosacea severity, stating their condition improved from a 10/10 to about 1.5/10 within six weeks of consistent zinc picolinate use Read Review. Another user reflected on their experience with facial breakouts, noting their daughter's acne largely cleared up after starting zinc supplementation Read Review. Additionally, a user highlighted improvements in skin elasticity and reduced oiliness after two months of use Read Review.
Apart from skin benefits, users frequently reported an increase in energy levels and overall vitality. One reviewer stated their chronic fatigue improved significantly after just two weeks of taking zinc Read Review. Another user, who had been struggling with low energy and was also managing an autoimmune disorder, expressed satisfaction with how the supplement boosted their well-being Read Review. Users also noted enhanced immunity, with many feeling less susceptible to colds and other illnesses during flu seasons Read Review, indicating zinc’s potential role in supporting immune health. While individual experiences can differ, the overall consensus points to zinc as a beneficial supplement for various health improvements.
Based on user reviews, many individuals with autoimmune disorders have reported positive experiences when combining zinc supplements with other vitamins. Users commonly mentioned taking zinc alongside potassium, magnesium, and B-complex vitamins, which contributed to improved energy levels and better management of their autoimmune conditions Read Review. A notable consensus emphasizes the effectiveness of combining zinc with vitamin D and C during cold seasons to bolster immunity and support overall health, particularly for those susceptible to illness Read Review.
However, experiences varied among users, with some reporting adverse effects when zinc was combined with other treatments Read Review. Several users highlighted that zinc picolinate was well-tolerated and showed significant improvements in skin health, energy, and immune function, making it a valuable addition to their supplement regimen Read Review. Overall, while many found success in using zinc as part of a broader health strategy, it's essential for individuals to monitor their responses and consult healthcare professionals when integrating supplements into their routines.
Based on user reviews, the appropriate dosing of zinc for treating autoimmune disorders appears to vary, with many users finding success with a daily intake of one tablet. For example, one reviewer reported significant improvement in their autoimmune symptoms after taking one zinc tablet daily, noting that it helped bolster their immune system during colder months Read Review. Similarly, another reviewer highlighted that one tablet daily was effective in managing inflammation and overall wellbeing related to their autoimmune condition Read Review.
However, some users have reported challenges with dosages, such as one individual experiencing digestive problems despite its benefits Read Review. This suggests that while many have found relief with standard dosing, sensitivity can vary widely. Users generally recommend starting with lower doses and adjusting based on personal tolerance, emphasizing the importance of consulting healthcare professionals before beginning supplementation, especially for specific health conditions like autoimmune disorders.
9
Cleared rosacea
6 people found this helpful
I researched the link between rosacea and zinc deficiency, which led me to order Solgar's zinc picolinate tablets. After taking one tablet daily, I noticed a significant improvement in my rosacea within six weeks, going from a 10/10 on the severity scale to about 1.5/10 now. These tablets are well absorbed and have worked wonderfully for me.
7.5
Enhanced well-being
8 people found this helpful
Taking zinc picolinate as prescribed transformed my overall wellbeing. Initially sceptical, I felt a marked improvement in fatigue and low energy after a week. I began with three tablets daily during illness, and my symptoms eased noticeably. I’ll continue taking it to bolster my immune system before winter arrives.
9
Reduced skin rashes
80 people found this helpful
I purchased zinc to combat skin rashes as advised by my doctor since it helps with acne and other skin concerns. After two months of consistent use, I've seen fewer rashes and improved skin elasticity. There were no gastrointestinal issues or allergies, and my hair and nails also appeared healthier. I will continue to buy Solgar zinc.
9
Acne reduction success
16 people found this helpful
My daughter used to suffer from facial breakouts, but ever since she started taking zinc, her acne has cleared up. Now, she insists I reorder as soon as possible whenever the symptoms return.
9
Reduced fatigue impact
6 people found this helpful
I ordered this product for my husband, who suffers from chronic fatigue and drowsiness due to his busy schedule. After two weeks of taking the zinc tablets, he has become much more energised and cheerful, which I attribute to the supplement's effectiveness. It also supports thyroid function and improves skin and nail health, reducing hair loss. Highly recommended!
8
Winter resilience
1 people found this helpful
I ordered zinc to help boost my immune system during the cold and flu season, especially given how rampant illness was in my city. It has certainly strengthened my immunity; I highly recommend it to anyone responsive to colds, particularly through the autumn and spring seasons!
9
Significant energy boost
256 people found this helpful
Many thanks to iHerb for the swift delivery and dependable packaging. Solgar's vitamins have truly transformed my health. I used to suffer from frequent colds and felt constantly fatigued, but after taking these vitamins, my energy levels soared, my complexion improved, and I’ve found it easier to manage my autoimmune disorder. My routine includes potassium, magnesium, a B-complex, and zinc in the evening.
7.5
Supports immunity
1 people found this helpful
Zinc positively affects my hair, nails, skin, and overall immunity while aiding enzyme production. Doctors recommend zinc, vitamin D, and vitamin C during cold seasons to support immunity and fight off illnesses, including issues related to autoimmune disorders. This zinc picolinate is effective and easily absorbed.
2
Panic attacks
1 people found this helpful
I have an autoimmune disorder, and after taking this supplement, I experienced a panic attack and a sensation of warmth in my throat. While it worked, it clearly does not suit everyone.
9
Positive skin effects
1 people found this helpful
I've ordered my second jar of zinc, which has positively impacted my skin, hair, and nails. By taking it regularly, my acne and skin irritations have diminished, and it increases scalp health. I prefer zinc picolinate for its absorption, which is essential for managing my autoimmune disorder effectively.
7.5
Support immune system
6 people found this helpful
The quality and ingredients are excellent, particularly the zinc in picolinate form, which supports the immune system. After experiencing a cold and hair loss during the summer, my doctor prescribed this zinc alongside other treatments. I took one tablet daily, and the improvement in my health has been remarkable. The tablets are small and easy to swallow. I frequently reorder this zinc for overall body health.
7.5
Skin and immunity improvement
31 people found this helpful
For me, this is the best zinc available. It has the right dosage and is well-absorbed with no side effects. I use it to support my immune system during ARVI, enhance my skin, and manage my autoimmune disorder's inflammatory responses. This zinc picolinate delivers excellent results. Five stars!
2
Pancreas reaction
10 people found this helpful
Zinc picolinate helped reduce my skin oiliness. However, it caused significant pancreatic reactions, leading to digestive issues despite its benefits for my autoimmune disorder. I had to stop taking it after trying a lower dosage.
8
Zinc transport's role in T cells
SLC39A10 is a key zinc transporter in T cells and its loss mitigates autoimmune disease.
We identified an important link between zinc transport and autoimmune disorders, specifically focusing on the protein SLC39A10 and its role in T cells. Through our study, we discovered that two specific genetic variations in the SLC39A10 gene are associated with inflammatory bowel disease (IBD). To further explore this connection, we created genetically modified mice with a targeted deletion of the Slc39a10 gene in T cells.
Our findings revealed that the loss of SLC39A10 significantly protects against the progression of both IBD and experimental autoimmune encephalomyelitis (EAE). Notably, we also observed that the absence of this transporter led to increased cell death, independent of common pathways usually associated with apoptosis. This indicates that SLC39A10 plays a crucial role in maintaining the health of T cells by facilitating zinc import, which is essential for DNA replication when T cells are activated.
Our research contributes to a deeper understanding of how zinc homeostasis impacts immune function. The insights gained from this study suggest that targeting zinc transport could present new therapeutic options for managing T cell-related autoimmune diseases.
9
Zinc supplementation benefits MS models
Dietary zinc status is associated with ZnT3 (SLC30A3), IL-6 gene expressions and spinal cord tissue damage in spinal cord tissue in a cuprizone-induced rat Multiple Sclerosis model.
We explored how dietary zinc levels influence spinal cord damage and gene expressions associated with Multiple Sclerosis (MS) using a cuprizone-induced rat model. The study included 46 adult male Wistar rats divided into five groups, with some receiving zinc supplementation while others followed a zinc-deficient diet.
After eight weeks of treatment, we found that the rats with MS symptoms showed elevated markers of tissue damage and inflammation, particularly in the groups that lacked zinc. Notably, those receiving zinc supplementation exhibited significantly reduced levels of harmful substances, bringing them back closer to control levels.
Our findings highlight zinc's protective effects in a model of MS, suggesting that incorporating zinc into treatment plans could help alleviate some symptoms associated with this autoimmune disorder. This is promising for future treatment strategies for those affected by MS.
4
Zinc intake influences autoimmune risk
Higher dietary zinc intake increases the risk of autoimmune thyroiditis.
We examined the connection between dietary zinc intake and the risk of autoimmune thyroiditis (AIT), particularly focusing on Hashimoto's thyroiditis. The study analyzed data from the 2007-2008 National Health and Nutrition Examination Survey, including nearly 5,500 participants—273 with AIT and 5,194 without it.
Our findings revealed that higher dietary zinc intake is associated with an increased risk of AIT, acting as an independent risk factor. This is concerning, as excessive zinc could disrupt our immune balance, potentially leading to other autoimmune disorders.
While it’s clear that zinc plays a role in thyroid health, we must be cautious about how much we consume. The study suggests that dietary zinc should be carefully monitored in those at risk for AIT, and it highlights the need for further research to establish safe consumption levels.
7
Zinc supplementation eases neutrophil activity
Zinc Supplementation Reduces the Formation of Neutrophil Extracellular Traps by Decreasing the Expression of Peptidyl Arginine Deiminase 4.
We aimed to explore how zinc supplementation might influence immune responses, particularly focusing on neutrophil activity in the context of autoimmune diseases. To do this, we simulated inflammatory conditions typically seen in such disorders using specific cytokines, interleukin-17 (IL-17) and tumor necrosis factor (TNF)-α.
Our findings indicated that elevating zinc levels significantly reduced the formation of neutrophil extracellular traps (NETs), which are often implicated in tissue damage during autoimmune flare-ups. We also discovered that zinc supplementation lowered the expression of a protein called peptidyl arginine deiminase 4 (PAD4), which is associated with NET formation.
Interestingly, zinc not only decreased harmful neutrophil activity but also boosted the production of beneficial proteins like interleukin-1 receptor antagonist (IL-1RA) and IL-8 in the activated cells. Overall, maintaining adequate zinc levels seems crucial for preserving healthy immune function and preventing the harmful overactivity of neutrophils, suggesting its potential as an adjunct treatment in managing autoimmune conditions.
References
Shao Y, Mu Q, Wang R, Luo H, Song Z, et al. SLC39A10 is a key zinc transporter in T cells and its loss mitigates autoimmune disease. Sci China Life Sci. 2025. 10.1007/s11427-024-2817-y
Chen L, Yan C, Huang C, Jiang Z, Lin R, et al. Higher dietary zinc intake increases the risk of autoimmune thyroiditis. Postgrad Med J. 2025. 10.1093/postmj/qgae202
Wu R, Li Y, Peng H, Yang Z, Wang Y, et al. Association Between Serum Trace Elements Level and Alopecia Areata: A Systematic Review and Meta-Analysis. J Cosmet Dermatol. 2025;24:e16740. 10.1111/jocd.16740
Bayiroglu AF, Acar G, Gulbahce-Mutlu E, Baltaci SB, Mogulkoc R, et al. Dietary zinc status is associated with ZnT3 (SLC30A3), IL-6 gene expressions and spinal cord tissue damage in spinal cord tissue in a cuprizone-induced rat Multiple Sclerosis model. J Trace Elem Med Biol. 2024;86:127540. 10.1016/j.jtemb.2024.127540
Fang D, Jiang D, Shi G, Song Y. The association between dietary zinc intake and osteopenia, osteoporosis in patients with rheumatoid arthritis. BMC Musculoskelet Disord. 2024;25:710. 10.1186/s12891-024-07768-5
Cheng J, Rink L, Wessels I. Zinc Supplementation Reduces the Formation of Neutrophil Extracellular Traps by Decreasing the Expression of Peptidyl Arginine Deiminase 4. Mol Nutr Food Res. 2024;68:e2400013. 10.1002/mnfr.202400013