Last update
5/22/2025

Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
USERS' SCORE
Good
Based on 837 Reviews
8
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Zinc (as zinc picolinate)
22 mg
200%

Top Medical Research Studies

8
Zinc’s effects on colds
We explored how zinc might help in treating and preventing the common cold. The study focused on zinc's effects, isolating it from other treatments to understand its true impact on cold symptoms. By doing this, the researchers aimed to clarify whether zinc could genuinely shorten the duration of a cold or alleviate its symptoms.

The findings were intriguing but showed that zinc might not yield significant benefits for everyone. While some individuals reported a slight reduction in cold symptoms, the evidence did not strongly support zinc as an effective treatment overall.

This means that, for those seeking relief from a nasty cold, zinc alone might not be the go-to solution we hoped it would be. It’s essential to consider this information when deciding on a cold treatment plan and to approach zinc with realistic expectations.
Read More
9
Zinc enhances rice cold resistance
We explored the impact of zinc-amino acids chelate on cold stress resistance in machine-transplanted early rice. Our investigation included other cold-resistant agents like uniconazole and abscisic acid, but we found zinc to be particularly effective. When applied during the regreening stage, zinc notably enhanced rice growth by promoting tillering and increasing the leaf area, which led to better yields.

We noted that zinc-amino acids chelate improved antioxidant enzyme activities, which are crucial for helping rice withstand cold temperatures. The yield of rice treated with zinc was approximately 9.22% higher than with uniconazole and 7.14% higher than with abscisic acid.

Additionally, we observed that using 750 g/ha of zinc-amino acids chelate during the transplanting and regreening stages yielded the best results. The timing of the application played a critical role, as spraying during these specific phases maximized both yield and cold resistance.

Overall, zinc treatments stand out as a promising option for improving cold stress resilience in early rice, making it a key consideration for farmers dealing with cold climate conditions.
Read More
We explored the impact of regular gargling with an antimicrobial mouthwash that contains both cetylpyridinium chloride and zinc on upper respiratory symptoms. A total of 150 participants were split into two groups; one group just brushed their teeth, while the other group brushed and gargled with the mouthwash twice a day over three months.

Our findings revealed that those using the mouthwash experienced a 21.5% reduction in the frequency and an 11% decrease in the severity of respiratory symptoms. This strongly suggests that incorporating zinc, alongside cetylpyridinium chloride, can provide benefits for those suffering from cold-related symptoms.

However, it’s important to note that this study’s design involved multiple components, and we can’t isolate zinc’s effectiveness from the impact of the other ingredients. Still, the results encourage us to view mouthwash with these ingredients as a helpful addition to our daily hygiene routines, especially during cold and flu season.

Ultimately, this research indicates that gargling with a mouthwash containing zinc and cetylpyridinium chloride can indeed help alleviate some unpleasant cold symptoms, but we should be mindful of the combination's effects when interpreting these outcomes.
Read More

Most Useful Reviews

10
Quickly combats cold
214 people found this helpful
Helps the immune system and quickly defeats the common cold. The results are excellent, with no side effects.
Read More
9
Reliable cold prevention
186 people found this helpful
After years of taking this product daily, I can confidently recommend it as a dependable immune booster. At 81 years old, I haven’t caught a cold or flu in many years, despite not receiving a flu shot!
Read More
9
Indispensable in winter
93 people found this helpful
The nutritionist recommended one capsule of zinc picolinate for my child as part of therapy. The child tolerates it well; we increase the dose during any hint of a cold. It's essential and effective.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
  • All Researches
9
Zinc enhances rice cold resistance
We explored the impact of zinc-amino acids chelate on cold stress resistance in machine-transplanted early rice. Our investigation included other cold-resistant agents like uniconazole and abscisic acid, but we found zinc to be particularly effective. When applied during the regreening stage, zinc notably enhanced rice growth by promoting tillering and increasing the leaf area, which led to better yields.

We noted that zinc-amino acids chelate improved antioxidant enzyme activities, which are crucial for helping rice withstand cold temperatures. The yield of rice treated with zinc was approximately 9.22% higher than with uniconazole and 7.14% higher than with abscisic acid.

Additionally, we observed that using 750 g/ha of zinc-amino acids chelate during the transplanting and regreening stages yielded the best results. The timing of the application played a critical role, as spraying during these specific phases maximized both yield and cold resistance.

Overall, zinc treatments stand out as a promising option for improving cold stress resilience in early rice, making it a key consideration for farmers dealing with cold climate conditions.
Read More
We explored the impact of regular gargling with an antimicrobial mouthwash that contains both cetylpyridinium chloride and zinc on upper respiratory symptoms. A total of 150 participants were split into two groups; one group just brushed their teeth, while the other group brushed and gargled with the mouthwash twice a day over three months.

Our findings revealed that those using the mouthwash experienced a 21.5% reduction in the frequency and an 11% decrease in the severity of respiratory symptoms. This strongly suggests that incorporating zinc, alongside cetylpyridinium chloride, can provide benefits for those suffering from cold-related symptoms.

However, it’s important to note that this study’s design involved multiple components, and we can’t isolate zinc’s effectiveness from the impact of the other ingredients. Still, the results encourage us to view mouthwash with these ingredients as a helpful addition to our daily hygiene routines, especially during cold and flu season.

Ultimately, this research indicates that gargling with a mouthwash containing zinc and cetylpyridinium chloride can indeed help alleviate some unpleasant cold symptoms, but we should be mindful of the combination's effects when interpreting these outcomes.
Read More
8
Zinc’s effects on colds
We explored how zinc might help in treating and preventing the common cold. The study focused on zinc's effects, isolating it from other treatments to understand its true impact on cold symptoms. By doing this, the researchers aimed to clarify whether zinc could genuinely shorten the duration of a cold or alleviate its symptoms.

The findings were intriguing but showed that zinc might not yield significant benefits for everyone. While some individuals reported a slight reduction in cold symptoms, the evidence did not strongly support zinc as an effective treatment overall.

This means that, for those seeking relief from a nasty cold, zinc alone might not be the go-to solution we hoped it would be. It’s essential to consider this information when deciding on a cold treatment plan and to approach zinc with realistic expectations.
Read More

User Reviews

USERS' SCORE
Good
Based on 837 Reviews
8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
10
Quickly combats cold
214 people found this helpful
Helps the immune system and quickly defeats the common cold. The results are excellent, with no side effects.
Read More
9
Reliable cold prevention
186 people found this helpful
After years of taking this product daily, I can confidently recommend it as a dependable immune booster. At 81 years old, I haven’t caught a cold or flu in many years, despite not receiving a flu shot!
Read More
9
Indispensable in winter
93 people found this helpful
The nutritionist recommended one capsule of zinc picolinate for my child as part of therapy. The child tolerates it well; we increase the dose during any hint of a cold. It's essential and effective.
Read More
9
Disappears cold symptoms
5 people found this helpful
I take 3 tablets at bedtime and 3 in the morning whenever I sense a cold or flu, and the symptoms vanish!
Read More
7.5
Immune system benefits
5 people found this helpful
Zinc Picolinate is the optimal formula for our bodies. It significantly strengthens the immune system and shields against infections. I take one tablet every evening for a month. At the first sign of a cold, I take three pills, and the illness soon recedes. Additionally, zinc is vital for maintaining hormonal balance in both men and women.
Read More

Frequently Asked Questions

9
Rapid cold relief
3 people found this helpful
It aids with colds! As soon as I feel unwell, my husband and I take 2 zinc tablets twice a day, and after 1-2 days, everything is fine. 👍🏻 The cold goes away; the key is not to delay treatment!
9
Quick recovery
2 people found this helpful
It works! Colds and malaise disappear within a couple of days.
10
Cold prevention
2 people found this helpful
Good cold remedy. I take one every day from October until February. During this time, I've had no colds, and if I feel even a hint of illness, it passes the next day. I believe zinc deserves the credit.
10
Excellent effect
At the first signs of a cold, I take this myself and give it to my daughter (15 years old). The effect is excellent; the cold recedes. We usually take it for 4-5 days. This coming cold season, I intend to use it for a month to prevent getting ill.
7.5
Immune system benefits
5 people found this helpful
Zinc Picolinate is the optimal formula for our bodies. It significantly strengthens the immune system and shields against infections. I take one tablet every evening for a month. At the first sign of a cold, I take three pills, and the illness soon recedes. Additionally, zinc is vital for maintaining hormonal balance in both men and women.
9
Easier colds
2 people found this helpful
For colds, it has a super effect! I give my children a tablet at the first signs of a cold for three days; they’ve been noticeably less ill and finally experienced autumn-winter without temperatures! I also took it myself for a week to treat my condition, and the white stripes on my nails disappeared.
9
Effective natural remedy
1 people found this helpful
In SARS, I take it with ARVI alongside Omega-3, vitamin D3, vitamin C, probiotics, and NAC (ACC). These remedies got me back on my feet in two days! I avoid useless pharmacy drugs, preferring natural treatments in substantial doses for colds. Recovery is swift and effortless. I highly recommend my first aid kit for both adults and children. Stay healthy! Thank you for your endorsement.
10
Recommended zinc supplement
Excellent zinc! I haven't had a single cold at all. I recommend it, but it's advisable to take it with copper as zinc can wash away copper, and deficiency leads to early greying of hair.
9
Boosts energy
1 people found this helpful
I love this zinc picolinate supplement. It's the best bioavailable zinc, helping me boost my immunity and combat colds. In winter, I take one capsule daily and feel more energetic and healthy. When I feel I'm about to get sick, I take 75 mg for a day or two, which helps me fight off a cold before it begins. Be mindful of dosage; listening to your body is crucial.
We explored the impact of regular gargling with an antimicrobial mouthwash that contains both cetylpyridinium chloride and zinc on upper respiratory symptoms. A total of 150 participants were split into two groups; one group just brushed their teeth, while the other group brushed and gargled with the mouthwash twice a day over three months.

Our findings revealed that those using the mouthwash experienced a 21.5% reduction in the frequency and an 11% decrease in the severity of respiratory symptoms. This strongly suggests that incorporating zinc, alongside cetylpyridinium chloride, can provide benefits for those suffering from cold-related symptoms.

However, it’s important to note that this study’s design involved multiple components, and we can’t isolate zinc’s effectiveness from the impact of the other ingredients. Still, the results encourage us to view mouthwash with these ingredients as a helpful addition to our daily hygiene routines, especially during cold and flu season.

Ultimately, this research indicates that gargling with a mouthwash containing zinc and cetylpyridinium chloride can indeed help alleviate some unpleasant cold symptoms, but we should be mindful of the combination's effects when interpreting these outcomes.
8
Zinc’s effects on colds
We explored how zinc might help in treating and preventing the common cold. The study focused on zinc's effects, isolating it from other treatments to understand its true impact on cold symptoms. By doing this, the researchers aimed to clarify whether zinc could genuinely shorten the duration of a cold or alleviate its symptoms.

The findings were intriguing but showed that zinc might not yield significant benefits for everyone. While some individuals reported a slight reduction in cold symptoms, the evidence did not strongly support zinc as an effective treatment overall.

This means that, for those seeking relief from a nasty cold, zinc alone might not be the go-to solution we hoped it would be. It’s essential to consider this information when deciding on a cold treatment plan and to approach zinc with realistic expectations.

References

  1. Muniz FWMG, Casarin M, Pola NM, Rösing CK, Silveira TMD, et al. Efficacy of regular gargling with a cetylpyridinium chloride plus zinc containing mouthwash can reduce upper respiratory symptoms. PLoS One. 2025;20:e0316807. 10.1371/journal.pone.0316807
  2. Wieland LS. Zinc for prevention and treatment of the common cold: Summary of a Cochrane review. Explore (NY). 2025;21:103111. 10.1016/j.explore.2025.103111
  3. Yuan S, Qin S, Shi Q, Chen P, Tu N, et al. Effects of different cold-resistant agents and application methods on yield and cold-resistance of machine-transplanted early rice. Front Plant Sci. 2024;15:1422374. 10.3389/fpls.2024.1422374
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