'
SCIENTIFIC SCORE
Questionable
Based on 4 Researches
5.5
USERS' SCORE
Good
Based on 72 Reviews
8.8
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Zinc (as zinc picolinate)
22 mg
200%

Top Medical Research Studies

7
Zinc treatment reduces nausea risk
Randomized, multicenter, active-controlled open-label study of NPC-25, zinc histidine hydrate, (non-inferiority to NOBELZIN™, zinc acetate dihydrate) for patients with hypozincemia.
Moderate relevance to nausea aspect
We conducted a study to evaluate how effective NPC-25, a new form of zinc, is compared to a well-known treatment, NOBELZIN™, for patients with low zinc levels. Participants in this trial had their zinc levels checked and were grouped to receive either NPC-25 or NOBELZIN™.

For a period of up to 24 weeks, we aimed to maintain their zinc levels within a specific target range while closely monitoring for side effects. One of our main goals was to see if NPC-25 could maintain these target zinc levels similarly to NOBELZIN™.

Our findings revealed that NPC-25 was indeed non-inferior to NOBELZIN™, meaning it worked just as well. Importantly, we also observed that those taking NPC-25 reported fewer digestive issues, like nausea and vomiting. This suggests that while both treatments were effective, NPC-25 might be the gentler option.
Read More
7
Zinc treatment in hypozincemia study
Post-marketing surveillance of zinc acetate dihydrate for hypozincemia in Japan.
Limited insight on nausea specifically
We explored the impact of zinc acetate dihydrate on several symptoms, including nausea, through a comprehensive study that assessed its safety and effectiveness for treating hypozincemia over a 52-week period. From the data collected, we observed an overall adverse reaction rate of 9.4%, with nausea reported in 1.4% of patients.

Despite nausea being a concern, the benefit of zinc acetate dihydrate for other indications was notable, with an efficacy rate of 83%. For patients experiencing symptoms such as pressure ulcers or stomatitis, the effectiveness was strikingly high. However, the specific effect of zinc on nausea is not definitively isolated within the study results, making it hard to gauge its direct and unique benefits.

In essence, while zinc acetate dihydrate shows promise for a variety of symptoms, including nausea, the evidence does not conclusively highlight its effectiveness for this particular issue on its own. Overall, it appears that zinc treatment can contribute positively to addressing several related health problems.
Read More
4
Zinc affects post-op nausea minimally
Comparing the Effect of Zinc-impregnated Pharyngeal Packs with Conventional Methods on the Level of Sore Throat Among Patients Undergoing Septorhinoplasty.
Relevant but limited impact
We explored the effectiveness of zinc-impregnated pharyngeal packs in reducing post-operative nausea and sore throat among patients undergoing septorhinoplasty. In this study, we divided 220 patients into four groups, each receiving different types of pharyngeal packs: normal saline-impregnated vibril, normal saline-impregnated gauze, zinc solution-impregnated vibril, and zinc solution-impregnated gauze.

Our findings revealed that there was no significant difference between the groups regarding the occurrence of sore throat shortly after surgery and at various intervals thereafter. However, we did observe that those using zinc solution-impregnated gauze experienced significantly less severity of nausea two hours post-surgery compared to those using normal saline-impregnated gauze. Ultimately, while zinc did not help with sore throat, it showed promise in alleviating nausea.
Read More

Most Useful Reviews

9.5
Nausea relief
Zinc from Solgar is excellent for my needs. I no longer experience nausea or swelling when taking it. I find it beneficial for healing mucous membranes and improving my skin, reducing acne and oily shine. This zinc has aided in my overall health, especially regarding recurrent issues like rhinitis and tonsillitis. It's easy to take, tiny tablets that dissolve quickly. I highly recommend it for anyone struggling with skin issues or related health problems.
Read More
9.5
No nausea experienced
The mood is positive, my hair is shiny, and my skin looks perfect thanks to this zinc from Solgar. I take one tablet daily and have not experienced any nausea or dizziness. I’m pleased with my decision to incorporate this into my routine for three months, followed by a break, as suggested.
Read More
9.5
Nausea-free experience
I've been taking zinc for years, but the Solgar picolinate suits me best. It's vital for immunity, easily digestible, and I haven't experienced any nausea like with other forms. I take it daily, and during illness, I increase the dosage. When I had COVID, I felt it helped me recover with milder symptoms. Highly recommend this form.
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 4 Researches
5.5
7
Zinc treatment reduces nausea risk
Randomized, multicenter, active-controlled open-label study of NPC-25, zinc histidine hydrate, (non-inferiority to NOBELZIN™, zinc acetate dihydrate) for patients with hypozincemia.
Moderate relevance to nausea aspect
We conducted a study to evaluate how effective NPC-25, a new form of zinc, is compared to a well-known treatment, NOBELZIN™, for patients with low zinc levels. Participants in this trial had their zinc levels checked and were grouped to receive either NPC-25 or NOBELZIN™.

For a period of up to 24 weeks, we aimed to maintain their zinc levels within a specific target range while closely monitoring for side effects. One of our main goals was to see if NPC-25 could maintain these target zinc levels similarly to NOBELZIN™.

Our findings revealed that NPC-25 was indeed non-inferior to NOBELZIN™, meaning it worked just as well. Importantly, we also observed that those taking NPC-25 reported fewer digestive issues, like nausea and vomiting. This suggests that while both treatments were effective, NPC-25 might be the gentler option.
Read More
7
Zinc treatment in hypozincemia study
Post-marketing surveillance of zinc acetate dihydrate for hypozincemia in Japan.
Limited insight on nausea specifically
We explored the impact of zinc acetate dihydrate on several symptoms, including nausea, through a comprehensive study that assessed its safety and effectiveness for treating hypozincemia over a 52-week period. From the data collected, we observed an overall adverse reaction rate of 9.4%, with nausea reported in 1.4% of patients.

Despite nausea being a concern, the benefit of zinc acetate dihydrate for other indications was notable, with an efficacy rate of 83%. For patients experiencing symptoms such as pressure ulcers or stomatitis, the effectiveness was strikingly high. However, the specific effect of zinc on nausea is not definitively isolated within the study results, making it hard to gauge its direct and unique benefits.

In essence, while zinc acetate dihydrate shows promise for a variety of symptoms, including nausea, the evidence does not conclusively highlight its effectiveness for this particular issue on its own. Overall, it appears that zinc treatment can contribute positively to addressing several related health problems.
Read More
4
Zinc affects post-op nausea minimally
Comparing the Effect of Zinc-impregnated Pharyngeal Packs with Conventional Methods on the Level of Sore Throat Among Patients Undergoing Septorhinoplasty.
Relevant but limited impact
We explored the effectiveness of zinc-impregnated pharyngeal packs in reducing post-operative nausea and sore throat among patients undergoing septorhinoplasty. In this study, we divided 220 patients into four groups, each receiving different types of pharyngeal packs: normal saline-impregnated vibril, normal saline-impregnated gauze, zinc solution-impregnated vibril, and zinc solution-impregnated gauze.

Our findings revealed that there was no significant difference between the groups regarding the occurrence of sore throat shortly after surgery and at various intervals thereafter. However, we did observe that those using zinc solution-impregnated gauze experienced significantly less severity of nausea two hours post-surgery compared to those using normal saline-impregnated gauze. Ultimately, while zinc did not help with sore throat, it showed promise in alleviating nausea.
Read More
4
Zinc's tolerability in diarrhoea treatment
New formulation zinc sulphate acceptability and adherence in children with acute diarrhoea: A prospective, open-label, interventional study in Bangladesh.
Explores nausea related to zinc
We aimed to understand how zinc tablets, often recommended for treating diarrhoea in young children, affect nausea and overall treatment adherence. In this open-label study, we involved children aged 3 to 59 months who visited the outpatient department at Dhaka Hospital.

Our findings revealed that a significant number of children, about 92.7%, tolerated the modified zinc tablets well. However, we also noted that 32.8% of the children experienced vomiting, and 19.5% had regurgitation, while a smaller number, 7.4%, reported nausea. Interestingly, despite these side effects, a remarkable 99.3% of caregivers expressed their willingness to continue using this zinc formulation in the future.

Overall, while our study demonstrated that the modified zinc formulation was generally well-tolerated, we cannot overlook the considerable instances of nausea and vomiting experienced by the children. Balancing these side effects with the willingness of caregivers offers a complex view of zinc's role in diarrhoea management.
Read More

User Reviews

USERS' SCORE
Good
Based on 72 Reviews
8.8
9.5
Nausea relief
Zinc from Solgar is excellent for my needs. I no longer experience nausea or swelling when taking it. I find it beneficial for healing mucous membranes and improving my skin, reducing acne and oily shine. This zinc has aided in my overall health, especially regarding recurrent issues like rhinitis and tonsillitis. It's easy to take, tiny tablets that dissolve quickly. I highly recommend it for anyone struggling with skin issues or related health problems.
Read More
9.5
No nausea experienced
The mood is positive, my hair is shiny, and my skin looks perfect thanks to this zinc from Solgar. I take one tablet daily and have not experienced any nausea or dizziness. I’m pleased with my decision to incorporate this into my routine for three months, followed by a break, as suggested.
Read More
9.5
Nausea-free experience
I've been taking zinc for years, but the Solgar picolinate suits me best. It's vital for immunity, easily digestible, and I haven't experienced any nausea like with other forms. I take it daily, and during illness, I increase the dosage. When I had COVID, I felt it helped me recover with milder symptoms. Highly recommend this form.
Read More
9.5
No nausea issues
I've been using zinc supplements, specifically this brand, and have had no nausea. It's crucial to take them post-hearty breakfast. Good dosage for colds too; I take two capsules for a few days then return to one. This zinc works well for me.
9.5
No adverse reactions
I use zinc for both skin treatment and my husband's testosterone levels. Many don't realise that topical zinc is ineffective; it needs to be taken internally. Unlike other brands that caused nausea, this zinc is well-tolerated and effective. I trust this brand and recommend it highly.
Read More
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