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SCIENTIFIC SCORE
Moderately Effective
Based on 10 Researches
8.3
USERS' SCORE
Moderately Good
Based on 7 Reviews
7.8
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Zinc (as zinc picolinate)
22 mg
200%
Top Medical Research Studies
9
New treatment reduces digital dermatitis
Investigation on the effectiveness of a new hoof care product to sustainably reduce and prevent digital dermatitis in dairy cow herds.
Mix limits zinc's isolated impact
We embarked on an investigation to understand whether a new hoof care product featuring iron, zinc, and aluminum can effectively reduce and prevent digital dermatitis (DD) in dairy cows. In a controlled trial involving over 130 dairy cows, we treated one hind foot of each cow twice a week with this product while leaving the other foot untreated for comparison.
The results were revealing! Our analysis indicated that the use of the hoof care product significantly reduced the severity of DD compared to the untreated group. In fact, cows treated with the product had a much lower chance of developing lesions. The outcome showed that in the control group, the odds of having a lesion were four times higher than in the treated group, and the likelihood of experiencing an active lesion versus an inactive one was even more pronounced.
Interestingly, we also observed positive outcomes in heifers, with only one developing an active lesion in the treated group, showcasing the potential for this product to help manage and prevent DD even before these young cows enter the herd. The study indicates that the combination of ingredients in this hoof care product could be a promising alternative to traditional, harsher treatments.
While zinc is included as one of the components in the product, it's essential to note that we can't isolate its effect on ulcers from the other ingredients. Therefore, we can't definitively conclude zinc's sole effectiveness when it comes to DD treatment, but the overall findings are encouraging for improving hoof health in dairy cows.
The results were revealing! Our analysis indicated that the use of the hoof care product significantly reduced the severity of DD compared to the untreated group. In fact, cows treated with the product had a much lower chance of developing lesions. The outcome showed that in the control group, the odds of having a lesion were four times higher than in the treated group, and the likelihood of experiencing an active lesion versus an inactive one was even more pronounced.
Interestingly, we also observed positive outcomes in heifers, with only one developing an active lesion in the treated group, showcasing the potential for this product to help manage and prevent DD even before these young cows enter the herd. The study indicates that the combination of ingredients in this hoof care product could be a promising alternative to traditional, harsher treatments.
While zinc is included as one of the components in the product, it's essential to note that we can't isolate its effect on ulcers from the other ingredients. Therefore, we can't definitively conclude zinc's sole effectiveness when it comes to DD treatment, but the overall findings are encouraging for improving hoof health in dairy cows.
Read More
9
Zinc-complex impacts ulcerative colitis
Qingzhuan dark tea polysaccharides-zinc alleviates dextran sodium sulfate-induced ulcerative colitis.
Indicates potential effectiveness
We delved into how a complex made from Qingzhuan dark tea polysaccharides and zinc, known as QDTP-Zn, can help with ulcerative colitis (UC) in mice. By inducing UC through a substance called dextran sodium sulfate, we were able to assess the protective effects of QDTP-Zn when administered orally at different doses.
Our findings revealed that QDTP-Zn significantly improved the symptoms of UC. We observed a reduction in disease activity, which indicates that the treatment was effective. Furthermore, QDTP-Zn seemed to enhance the health of colon tissues by increasing levels of important proteins while simultaneously reducing inflammatory markers.
Interestingly, the treatment influenced the makeup of gut microbiota and boosted levels of short-chain fatty acids, which are essential for gut health. This suggests that zinc, when combined with QDTP, plays a role in strengthening gut barriers, reducing inflammation, and promoting beneficial microbial populations.
In conclusion, our research highlights the promise of QDTP-Zn as a potential food supplement that could be used for both the prevention and management of ulcerative colitis, showcasing the therapeutic power of combining zinc with natural polysaccharides.
Our findings revealed that QDTP-Zn significantly improved the symptoms of UC. We observed a reduction in disease activity, which indicates that the treatment was effective. Furthermore, QDTP-Zn seemed to enhance the health of colon tissues by increasing levels of important proteins while simultaneously reducing inflammatory markers.
Interestingly, the treatment influenced the makeup of gut microbiota and boosted levels of short-chain fatty acids, which are essential for gut health. This suggests that zinc, when combined with QDTP, plays a role in strengthening gut barriers, reducing inflammation, and promoting beneficial microbial populations.
In conclusion, our research highlights the promise of QDTP-Zn as a potential food supplement that could be used for both the prevention and management of ulcerative colitis, showcasing the therapeutic power of combining zinc with natural polysaccharides.
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8
Zinc's Impact on Chronic Ulcers
Impact of oral nutritional supplement composition on healing of different chronic wounds: A systematic review.
Limited isolated effect observed
We set out to explore how zinc, when included in oral nutritional formulas, impacts the healing of chronic ulcers. Our investigation looked at various research involving a total of 741 patients with different types of wounds, which primarily included pressure injuries and diabetic foot ulcers.
Among the studies we examined, some suggested that a hypercaloric and hyperproteic formula enriched with zinc, along with important vitamins A, C, and E, could promote wound healing effectively. Specifically, four studies indicated that these enriched formulas led to a noticeable reduction in wound area, showcasing an increase in healing rates.
However, it's worth noting that two studies reported no significant differences in healing rates when zinc was incorporated into the treatment. Additionally, other approaches featuring combinations like arginine and glutamine did not show significant improvements over the control groups, further complicating the picture.
This indicates that while zinc might play a beneficial role, the evidence isn't uniformly strong regarding its isolated effect on ulcer healing. Overall, we found that a desirable formula for promoting healing seems to focus on high calories, protein content, and antioxidants, which may include zinc as part of a larger cocktail of nutrients.
Among the studies we examined, some suggested that a hypercaloric and hyperproteic formula enriched with zinc, along with important vitamins A, C, and E, could promote wound healing effectively. Specifically, four studies indicated that these enriched formulas led to a noticeable reduction in wound area, showcasing an increase in healing rates.
However, it's worth noting that two studies reported no significant differences in healing rates when zinc was incorporated into the treatment. Additionally, other approaches featuring combinations like arginine and glutamine did not show significant improvements over the control groups, further complicating the picture.
This indicates that while zinc might play a beneficial role, the evidence isn't uniformly strong regarding its isolated effect on ulcer healing. Overall, we found that a desirable formula for promoting healing seems to focus on high calories, protein content, and antioxidants, which may include zinc as part of a larger cocktail of nutrients.
Read More
Most Useful Reviews
6.8
Gastritis and ulcers
This zinc is bioavailable and was prescribed for acne, though I didn't see improvements there. However, it works well for respiratory issues and heals gastritis and ulceration of the intestinal mucosa. I advise caution with long-term high doses.
Read More
9.5
Faster healing
I love this! I started taking it for mouth ulcers; it seems to help them heal quicker. I now take it daily for my immunity and have noticed smoother skin since. I experienced no adverse effects like nausea.
Read More
9.5
Ulcer healing benefits
I began taking zinc due to loss of smell and learned it heals ulcers and relieves inflammation. After 5 months, it suited my ulcer condition and colitis, showing great benefits confirmed by my colonoscopy. I wholeheartedly recommend this zinc.
Read More
Most Recommended Products for Ulcer
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 10 Researches
8.3
9.5
Zinc's role in ulcer treatment
[Argentinean registry on the management of Helicobacter pylori infection: effectiveness and safety of first line treatment].
Effectiveness of combined therapies
We explored the impact of zinc when incorporated into first-line treatments for Helicobacter pylori infections, particularly in patients suffering from ulcers. In a multicenter registry study involving 800 patients, we noted that the most common factors leading to treatment were dyspepsia and gastroduodenal ulcers.
The findings indicated that quadruple therapy—both with and without bismuth—improved eradication rates significantly, achieving about 94.9%. Meanwhile, zinc as a part of a sequential therapy showed an impressive effectiveness of 95.6%. However, since zinc was combined with other treatments, it’s challenging to pinpoint its isolated effects on ulcer healing or eradication efficacy.
We also observed that adverse events, though reported in nearly 29% of cases, were generally mild, suggesting that the treatments were well-tolerated. Overall, the report highlighted that while zinc may enhance treatment effectiveness when combined, its individual contribution remains undetermined.
The findings indicated that quadruple therapy—both with and without bismuth—improved eradication rates significantly, achieving about 94.9%. Meanwhile, zinc as a part of a sequential therapy showed an impressive effectiveness of 95.6%. However, since zinc was combined with other treatments, it’s challenging to pinpoint its isolated effects on ulcer healing or eradication efficacy.
We also observed that adverse events, though reported in nearly 29% of cases, were generally mild, suggesting that the treatments were well-tolerated. Overall, the report highlighted that while zinc may enhance treatment effectiveness when combined, its individual contribution remains undetermined.
Read More
9
Zinc treatment has therapeutic potential
Treatment of Acute Ulcerative Colitis with Zinc Hyaluronate in Mice.
Part of combination treatment insights.
We investigated the effects of zinc hyaluronate (ZnHA) on ulcerative colitis (UC) using a mouse model that simulates the condition. This study aimed to explore how ZnHA could potentially alleviate the symptoms of UC, focusing on factors like inflammation and gut health.
Our experiments showed that ZnHA significantly reduced key symptoms associated with UC, such as weight loss, loose stools, and the presence of blood in stools. We also noticed notable changes at a cellular level; ZnHA helped decrease levels of inflammatory markers like tumor necrosis factor-α and interleukin-6 while boosting interleukin-10, a factor known for anti-inflammatory effects.
Additionally, our findings revealed that ZnHA positively impacted gut bacteria. It fostered the growth of beneficial bacteria that produce propionic acid, which is crucial for gut health. We also observed that ZnHA enhanced the function of proteins that maintain the intestinal barrier, such as ZO-1 and occludin.
Overall, our exploration highlights the potential of ZnHA as a supportive treatment for UC by targeting inflammation and promoting a healthy gut environment. This study provides new insights that could encourage further development of hyaluronic acid-based treatments for UC and similar conditions.
Our experiments showed that ZnHA significantly reduced key symptoms associated with UC, such as weight loss, loose stools, and the presence of blood in stools. We also noticed notable changes at a cellular level; ZnHA helped decrease levels of inflammatory markers like tumor necrosis factor-α and interleukin-6 while boosting interleukin-10, a factor known for anti-inflammatory effects.
Additionally, our findings revealed that ZnHA positively impacted gut bacteria. It fostered the growth of beneficial bacteria that produce propionic acid, which is crucial for gut health. We also observed that ZnHA enhanced the function of proteins that maintain the intestinal barrier, such as ZO-1 and occludin.
Overall, our exploration highlights the potential of ZnHA as a supportive treatment for UC by targeting inflammation and promoting a healthy gut environment. This study provides new insights that could encourage further development of hyaluronic acid-based treatments for UC and similar conditions.
Read More
9
Zinc enhances diabetic ulcer healing
Enhanced diabetic foot ulcer treatment with a chitosan-based thermosensitive hydrogel loaded self-assembled multi-functional nanoparticles for antibacterial and angiogenic effects.
Significant contribution of zinc noted
We explored how a new treatment for diabetic foot ulcers (DFUs) works, focusing on the role of zinc. This innovative formulation combines zinc with other therapeutic agents in a chitosan-based hydrogel that responds to heat. Our aim was to see if this treatment could not only fight bacteria but also help the body heal more effectively.
The combination of zinc with chlorogenic acid and indocyanine green promotes a healing environment by reducing inflammation and oxidative stress at the ulcer site. This hydrogel is designed to release its active ingredients right where they’re needed, and we found that it significantly enhances the expression of proteins important for blood vessel formation, including VEGF and CD31.
In our experiments, both in the lab and in real-life conditions, this zinc-enriched hydrogel showed promising results. It effectively inhibited the growth of the common bacteria Staphylococcus aureus after applying laser treatment and helped wounds remodel within 14 days.
This study suggests that incorporating zinc into wound care strategies could significantly improve treatment outcomes for patients suffering from DFUs. Overall, our findings open up new avenues for managing this challenging health issue.
The combination of zinc with chlorogenic acid and indocyanine green promotes a healing environment by reducing inflammation and oxidative stress at the ulcer site. This hydrogel is designed to release its active ingredients right where they’re needed, and we found that it significantly enhances the expression of proteins important for blood vessel formation, including VEGF and CD31.
In our experiments, both in the lab and in real-life conditions, this zinc-enriched hydrogel showed promising results. It effectively inhibited the growth of the common bacteria Staphylococcus aureus after applying laser treatment and helped wounds remodel within 14 days.
This study suggests that incorporating zinc into wound care strategies could significantly improve treatment outcomes for patients suffering from DFUs. Overall, our findings open up new avenues for managing this challenging health issue.
Read More
9
New treatment reduces digital dermatitis
Investigation on the effectiveness of a new hoof care product to sustainably reduce and prevent digital dermatitis in dairy cow herds.
Mix limits zinc's isolated impact
We embarked on an investigation to understand whether a new hoof care product featuring iron, zinc, and aluminum can effectively reduce and prevent digital dermatitis (DD) in dairy cows. In a controlled trial involving over 130 dairy cows, we treated one hind foot of each cow twice a week with this product while leaving the other foot untreated for comparison.
The results were revealing! Our analysis indicated that the use of the hoof care product significantly reduced the severity of DD compared to the untreated group. In fact, cows treated with the product had a much lower chance of developing lesions. The outcome showed that in the control group, the odds of having a lesion were four times higher than in the treated group, and the likelihood of experiencing an active lesion versus an inactive one was even more pronounced.
Interestingly, we also observed positive outcomes in heifers, with only one developing an active lesion in the treated group, showcasing the potential for this product to help manage and prevent DD even before these young cows enter the herd. The study indicates that the combination of ingredients in this hoof care product could be a promising alternative to traditional, harsher treatments.
While zinc is included as one of the components in the product, it's essential to note that we can't isolate its effect on ulcers from the other ingredients. Therefore, we can't definitively conclude zinc's sole effectiveness when it comes to DD treatment, but the overall findings are encouraging for improving hoof health in dairy cows.
The results were revealing! Our analysis indicated that the use of the hoof care product significantly reduced the severity of DD compared to the untreated group. In fact, cows treated with the product had a much lower chance of developing lesions. The outcome showed that in the control group, the odds of having a lesion were four times higher than in the treated group, and the likelihood of experiencing an active lesion versus an inactive one was even more pronounced.
Interestingly, we also observed positive outcomes in heifers, with only one developing an active lesion in the treated group, showcasing the potential for this product to help manage and prevent DD even before these young cows enter the herd. The study indicates that the combination of ingredients in this hoof care product could be a promising alternative to traditional, harsher treatments.
While zinc is included as one of the components in the product, it's essential to note that we can't isolate its effect on ulcers from the other ingredients. Therefore, we can't definitively conclude zinc's sole effectiveness when it comes to DD treatment, but the overall findings are encouraging for improving hoof health in dairy cows.
Read More
9
Zinc and Polaprezinc's synergistic effects
Aspergillusidone G Potentiates the Anti-Inflammatory Effects of Polaprezinc in LPS-Induced BV2 Microglia: A Bioinformatics and Experimental Study.
Explored zinc’s ulcer connection
We explored the potential impact of Polaprezinc, a drug commonly used for gastric ulcers, on neuroinflammation, a key factor in neurodegenerative diseases. By using LPS-induced BV-2 microglia, we observed that Polaprezinc significantly reduced the production of harmful compounds like nitric oxide and reactive oxygen species. Additionally, it inhibited the expression of inflammatory markers, suggesting its anti-inflammatory properties may extend beyond ulcer treatment.
Interestingly, we also examined how the combination of Polaprezinc with Aspergillusidone G could enhance these effects. When we treated the microglia with both substances, the results were promising. The duo improved the inhibition of nitric oxide generation from about 30% to an impressive 80%. This indicates a possible synergistic anti-inflammatory effect that could offer new approaches in managing neuroinflammatory conditions.
Overall, our findings shed light on the importance of zinc's role in the therapeutic effects of Polaprezinc, especially when paired with other compounds like Aspergillusidone G. This combination opens up exciting avenues for research into treatments for neurodegenerative diseases, highlighting the crucial connection between inflammation and zinc in the context of ulcer management.
Interestingly, we also examined how the combination of Polaprezinc with Aspergillusidone G could enhance these effects. When we treated the microglia with both substances, the results were promising. The duo improved the inhibition of nitric oxide generation from about 30% to an impressive 80%. This indicates a possible synergistic anti-inflammatory effect that could offer new approaches in managing neuroinflammatory conditions.
Overall, our findings shed light on the importance of zinc's role in the therapeutic effects of Polaprezinc, especially when paired with other compounds like Aspergillusidone G. This combination opens up exciting avenues for research into treatments for neurodegenerative diseases, highlighting the crucial connection between inflammation and zinc in the context of ulcer management.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 7 Reviews
7.8
9.5
Faster healing
I love this! I started taking it for mouth ulcers; it seems to help them heal quicker. I now take it daily for my immunity and have noticed smoother skin since. I experienced no adverse effects like nausea.
9.5
Ulcer healing benefits
I began taking zinc due to loss of smell and learned it heals ulcers and relieves inflammation. After 5 months, it suited my ulcer condition and colitis, showing great benefits confirmed by my colonoscopy. I wholeheartedly recommend this zinc.
8.8
Healing leg ulcer
This was recommended to aid in healing a leg ulcer and was good value for money in terms of size and price.
8.8
Ulcer treatment
A highly absorbable zinc is vital for the immune system and effective in wound healing. It's often used in hospitals for burns and ulcers and possesses antioxidant properties in preventing chronic diseases.
8
Mouth ulcer relief
This is one of the better forms of zinc that is absorbed well. It helps me with mouth ulcers and I take this supplement year-round.
