Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7
USERS' SCORE
Good
Based on 8 Reviews
8.1
Supplement Facts
Serving Size: 3 Tablets
Amount Per Serving
%DV
Calories
10
Total Carbohydrate
3 g
1%*
Magnesium (as magnesium malate trihydrate)
425 mg
101%
Sodium
10 mg
<1%
Magnesium Malate Trihydrate
3.75 g
†
Malic Acid (as magnesium malate trihydrate and malic acid)
2.5 g
†
Top Medical Research Studies
7
We investigated how choline magnesium trisalicylate (CMT) helps alleviate bone pain in patients with metastatic cancer. In a carefully designed study involving 26 participants, we compared CMT against a placebo in a crossover format, measuring pain relief at multiple intervals after dosing.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
Read More
7
We evaluated the effects of pamidronate therapy on children with osteogenesis imperfecta type III. Over the course of treatment, we saw reductions in bone pain, alongside a significant decrease in fracture incidence.
The therapy positively impacted children's daily activities and their overall mobility. Importantly, the treatment was found to be safe, although some patients experienced mild side effects like low calcium levels and a fever. Overall, our findings suggest that bisphosphonate therapy is beneficial for management in these young patients.
The therapy positively impacted children's daily activities and their overall mobility. Importantly, the treatment was found to be safe, although some patients experienced mild side effects like low calcium levels and a fever. Overall, our findings suggest that bisphosphonate therapy is beneficial for management in these young patients.
Read More
7
Promising drug delivery for osteoporosis
We developed a novel drug delivery system combining denosumab and magnesium within metal-organic frameworks to target osteoarthritis. The framework showed good potential for loaded drug release, delivering about 72% of denosumab in just 8 hours.
Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
Read More
Most Useful Reviews
7.5
Reduced muscle pain
7 people found this helpful
1250mg of magnesium malate has made a noticeable difference for me. While it may take weeks or months to fully evaluate its effectiveness, I can confirm that my numerous muscle pains have become bearable. Despite relying on over a dozen prescription medications daily, nothing has alleviated my pain as much as magnesium. Even my arthritis in the knees has improved significantly. I have spent over $2,000 on ineffective injections, yet this supplement has no side effects or adverse symptoms, only positive feelings. For now, it deserves a score of 4, possibly rising to 5.
Read More
9
Bone health assurance
3 people found this helpful
I have been using magnesium for years to maintain my bone strength. After twisting my leg last year, the doctor confirmed my bones are robust for my age of 82. So, I assume it works well. A simple exercise helped my leg recover.
Read More
9
Improved well-being
1 people found this helpful
Magnesium is essential for maintaining bone and dental health; it aids in nerve signal transmission and energy production; enhances vitamin absorption; accelerates tissue repair; and positively influences the nervous system. After starting Magnesium, my headaches diminished, symptoms of restless legs syndrome disappeared, and I began to sleep better. I can confidently say that magnesium is beneficial for everyone.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7
- All Researches
7
Promising drug delivery for osteoporosis
We developed a novel drug delivery system combining denosumab and magnesium within metal-organic frameworks to target osteoarthritis. The framework showed good potential for loaded drug release, delivering about 72% of denosumab in just 8 hours.
Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
Read More
7
We evaluated the effects of pamidronate therapy on children with osteogenesis imperfecta type III. Over the course of treatment, we saw reductions in bone pain, alongside a significant decrease in fracture incidence.
The therapy positively impacted children's daily activities and their overall mobility. Importantly, the treatment was found to be safe, although some patients experienced mild side effects like low calcium levels and a fever. Overall, our findings suggest that bisphosphonate therapy is beneficial for management in these young patients.
The therapy positively impacted children's daily activities and their overall mobility. Importantly, the treatment was found to be safe, although some patients experienced mild side effects like low calcium levels and a fever. Overall, our findings suggest that bisphosphonate therapy is beneficial for management in these young patients.
Read More
7
We investigated how choline magnesium trisalicylate (CMT) helps alleviate bone pain in patients with metastatic cancer. In a carefully designed study involving 26 participants, we compared CMT against a placebo in a crossover format, measuring pain relief at multiple intervals after dosing.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
Read More
User Reviews
USERS' SCORE
Good
Based on 8 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Reduced muscle pain
7 people found this helpful
1250mg of magnesium malate has made a noticeable difference for me. While it may take weeks or months to fully evaluate its effectiveness, I can confirm that my numerous muscle pains have become bearable. Despite relying on over a dozen prescription medications daily, nothing has alleviated my pain as much as magnesium. Even my arthritis in the knees has improved significantly. I have spent over $2,000 on ineffective injections, yet this supplement has no side effects or adverse symptoms, only positive feelings. For now, it deserves a score of 4, possibly rising to 5.
Read More
9
Bone health assurance
3 people found this helpful
I have been using magnesium for years to maintain my bone strength. After twisting my leg last year, the doctor confirmed my bones are robust for my age of 82. So, I assume it works well. A simple exercise helped my leg recover.
Read More
9
Improved well-being
1 people found this helpful
Magnesium is essential for maintaining bone and dental health; it aids in nerve signal transmission and energy production; enhances vitamin absorption; accelerates tissue repair; and positively influences the nervous system. After starting Magnesium, my headaches diminished, symptoms of restless legs syndrome disappeared, and I began to sleep better. I can confidently say that magnesium is beneficial for everyone.
Read More
7.5
Overall improvements
1 people found this helpful
Magnesium enhances energy and supports healthy bones and cardiovascular systems. I repeatedly order it due to its ideal absorption qualities. It's a superb supplement that aids in sleep and muscle cramps, particularly reducing joint pain. The price, quality, and natural ingredients make this a very beneficial mineral.
Read More
7.5
Enhanced body functions
93 people found this helpful
I previously neglected magnesium but realised it’s vital for preparing my body for a "cleaning" process. The malate form is highly recommended as it’s well absorbed. Magnesium is crucial for many body processes, including digestion and energy production. I take one tablet of magnesium with calcium in the evening and find that it enhances my sleep quality and makes mornings easier.
Read More
Frequently Asked Questions
7.5
Fibromyalgia symptoms
I’ve found this magnesium form significantly helps manage my Fibromyalgia symptoms. I can navigate my day with greater energy and reduced pain.
7.5
Positive impact
Magnesium is an excellent, carefree form, vital for ongoing use. It positively affects sleep, relieves muscle tension, and is beneficial for joint pain.
9
Bone health assurance
3 people found this helpful
I have been using magnesium for years to maintain my bone strength. After twisting my leg last year, the doctor confirmed my bones are robust for my age of 82. So, I assume it works well. A simple exercise helped my leg recover.
9
Improved well-being
1 people found this helpful
Magnesium is essential for maintaining bone and dental health; it aids in nerve signal transmission and energy production; enhances vitamin absorption; accelerates tissue repair; and positively influences the nervous system. After starting Magnesium, my headaches diminished, symptoms of restless legs syndrome disappeared, and I began to sleep better. I can confidently say that magnesium is beneficial for everyone.
7.5
Enhanced body functions
93 people found this helpful
I previously neglected magnesium but realised it’s vital for preparing my body for a "cleaning" process. The malate form is highly recommended as it’s well absorbed. Magnesium is crucial for many body processes, including digestion and energy production. I take one tablet of magnesium with calcium in the evening and find that it enhances my sleep quality and makes mornings easier.
7
We investigated how choline magnesium trisalicylate (CMT) helps alleviate bone pain in patients with metastatic cancer. In a carefully designed study involving 26 participants, we compared CMT against a placebo in a crossover format, measuring pain relief at multiple intervals after dosing.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
7
Promising drug delivery for osteoporosis
We developed a novel drug delivery system combining denosumab and magnesium within metal-organic frameworks to target osteoarthritis. The framework showed good potential for loaded drug release, delivering about 72% of denosumab in just 8 hours.
Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
References
- Alsaikhan F, Mahmoud MZ, Suliman M. Synthesis and characterization of novel denosumab/magnesium-based metal organic frameworks nanocomposite prepared by ultrasonic route as drug delivery system for the treatment of osteoporosis. Front Bioeng Biotechnol. 2023;11:1153969. doi:10.3389/fbioe.2023.1153969
- Jakubowska-Pietkiewicz E, Chlebna-Sokół D. New trends in the treatment of osteogenesis imperfecta type III - own experience. Ortop Traumatol Rehabil. 2008;10:593.
- Johnson JR, Miller AJ. The efficacy of choline magnesium trisalicylate (CMT) in the management of metastatic bone pain: a pilot study. Palliat Med. 1994;8:129.
