Overview
SCIENTIFIC SCORE
Likely Ineffective
Based on 17 Researches
4.8
USERS' SCORE
Good
Based on 115 Reviews
8.6
Supplement Facts
Serving Size: 3 Tablets
Amount Per Serving
%DV
Calories
10
Total Carbohydrate
3 g
1%*
Magnesium (as magnesium malate trihydrate)
425 mg
101%
Sodium
10 mg
<1%
Magnesium Malate Trihydrate
3.75 g
†
Malic Acid (as magnesium malate trihydrate and malic acid)
2.5 g
†
Top Medical Research Studies
9
Magnesium oxide treats leg cramps
We conducted a study to evaluate how effective magnesium oxide monohydrate (MOMH) is in treating nocturnal leg cramps (NLC). This was a randomized, double-blind, placebo-controlled trial involving multiple centers in Ukraine, where participants took either MOMH or a placebo nightly for 60 days.
Our focus was on measuring the frequency and duration of cramps, the pain they caused, and how they affected sleep quality and overall life satisfaction. We used thorough statistical methods to compare the results between the two groups.
The findings indicated that MOMH is both effective and safe for individuals dealing with NLC. Participants reported improvements in their symptoms, demonstrating that this magnesium supplement can play a helpful role in managing nocturnal leg cramps.
Our focus was on measuring the frequency and duration of cramps, the pain they caused, and how they affected sleep quality and overall life satisfaction. We used thorough statistical methods to compare the results between the two groups.
The findings indicated that MOMH is both effective and safe for individuals dealing with NLC. Participants reported improvements in their symptoms, demonstrating that this magnesium supplement can play a helpful role in managing nocturnal leg cramps.
Read More
9
We sought to understand the effectiveness of oral magnesium in treating leg cramps experienced by pregnant women. Our study was well-structured, involving a double-blind, randomized, placebo-controlled design. It included 86 healthy pregnant women between 14 to 34 weeks of gestation who encountered leg cramps at least twice a week, and we followed them over a four-week period.
At the end of the study, we discovered that the women taking magnesium bisglycinate chelate (300 mg per day) reported a significant reduction in cramp frequency—86% experienced at least a 50% drop compared to only 60.5% of those taking the placebo. Additionally, those on magnesium also noted a notable decrease in cramp intensity, with 69.8% achieving a similar improvement versus just 48.8% in the placebo group.
Encouragingly, we found no major side effects reported in either group, such as nausea or diarrhea. Our findings suggest that magnesium supplements can effectively reduce both the frequency and severity of leg cramps during pregnancy, offering a potential treatment option for women dealing with this common issue.
At the end of the study, we discovered that the women taking magnesium bisglycinate chelate (300 mg per day) reported a significant reduction in cramp frequency—86% experienced at least a 50% drop compared to only 60.5% of those taking the placebo. Additionally, those on magnesium also noted a notable decrease in cramp intensity, with 69.8% achieving a similar improvement versus just 48.8% in the placebo group.
Encouragingly, we found no major side effects reported in either group, such as nausea or diarrhea. Our findings suggest that magnesium supplements can effectively reduce both the frequency and severity of leg cramps during pregnancy, offering a potential treatment option for women dealing with this common issue.
Read More
7
We set out to investigate whether magnesium citrate could be an effective remedy for those who experience bothersome leg cramps, particularly at night. In our study, we used a randomised, double-blind, cross-over, placebo-controlled design to ensure reliable results. Participants suffering from regular leg cramps were recruited and given either magnesium citrate or a matching placebo over six weeks.
Our findings revealed that those who began the trial with the placebo experienced an average reduction in cramps when taking magnesium, with a median of 5 cramps compared to 9 on the placebo. Moreover, a notable percentage of participants felt that the magnesium treatment had indeed helped them, with 78% reporting benefits, as opposed to 54% who felt the placebo was effective.
While these results suggest that magnesium may have a positive impact, it’s essential to mention that the impact on cramp severity and duration wasn’t significantly different between the two groups. Additionally, some participants did report experiencing diarrhoea as a side effect of magnesium. Overall, we believe magnesium shows promise in alleviating nocturnal leg cramps and recommend further research to fully evaluate its effectiveness.
Our findings revealed that those who began the trial with the placebo experienced an average reduction in cramps when taking magnesium, with a median of 5 cramps compared to 9 on the placebo. Moreover, a notable percentage of participants felt that the magnesium treatment had indeed helped them, with 78% reporting benefits, as opposed to 54% who felt the placebo was effective.
While these results suggest that magnesium may have a positive impact, it’s essential to mention that the impact on cramp severity and duration wasn’t significantly different between the two groups. Additionally, some participants did report experiencing diarrhoea as a side effect of magnesium. Overall, we believe magnesium shows promise in alleviating nocturnal leg cramps and recommend further research to fully evaluate its effectiveness.
Read More
Most Useful Reviews
9
Supports muscular system
143 people found this helpful
Very good quality magnesium. My husband takes it as recommended by his doctor. He takes three tablets daily, and it supports his muscle system effectively. His nocturnal leg cramps and twitching have disappeared while benefiting his heart.
Read More
7.5
Overall wellbeing improved
122 people found this helpful
One of the best magnesium supplements! It works splendidly, particularly when paired with vitamin B6. It effectively tackled my night cramps linked to magnesium deficiency. I've noticed an improvement in my overall emotional state as well.
Read More
9
Increased morning energy
105 people found this helpful
Great magnesium! I take two capsules daily after breakfast. It has eradicated my leg cramps, boosted my energy, and made waking up in the morning much easier. My nerves feel less strained too.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Ineffective
Based on 17 Researches
4.8
- All Researches
9.5
We explored the effects of magnesium treatment in a unique case involving a 62-year-old woman with stage IV colon cancer undergoing oxaliplatin therapy. Shortly after her first infusion, we observed that she experienced significant neurological symptoms, including right hemibody paresthesia, muscle cramping in her right calf, and dysphonia.
To address these symptoms, she was administered intravenous magnesium sulfate along with calcium gluconate. Remarkably, within three hours, all her symptoms resolved. While this case suggests that magnesium can provide relief from cramps and other neurological side effects, it is important to note that magnesium was used in conjunction with other medications, making it challenging to assess its isolated effectiveness.
For future doses, the oxaliplatin was adjusted by reducing the dose and extending the infusion duration, which minimized her symptoms to occasional mild paresthesia. In summary, while magnesium showed promise in this case, further research is needed to determine its specific impact on leg cramps in a clearer, more controlled manner.
To address these symptoms, she was administered intravenous magnesium sulfate along with calcium gluconate. Remarkably, within three hours, all her symptoms resolved. While this case suggests that magnesium can provide relief from cramps and other neurological side effects, it is important to note that magnesium was used in conjunction with other medications, making it challenging to assess its isolated effectiveness.
For future doses, the oxaliplatin was adjusted by reducing the dose and extending the infusion duration, which minimized her symptoms to occasional mild paresthesia. In summary, while magnesium showed promise in this case, further research is needed to determine its specific impact on leg cramps in a clearer, more controlled manner.
Read More
9
Magnesium oxide treats leg cramps
We conducted a study to evaluate how effective magnesium oxide monohydrate (MOMH) is in treating nocturnal leg cramps (NLC). This was a randomized, double-blind, placebo-controlled trial involving multiple centers in Ukraine, where participants took either MOMH or a placebo nightly for 60 days.
Our focus was on measuring the frequency and duration of cramps, the pain they caused, and how they affected sleep quality and overall life satisfaction. We used thorough statistical methods to compare the results between the two groups.
The findings indicated that MOMH is both effective and safe for individuals dealing with NLC. Participants reported improvements in their symptoms, demonstrating that this magnesium supplement can play a helpful role in managing nocturnal leg cramps.
Our focus was on measuring the frequency and duration of cramps, the pain they caused, and how they affected sleep quality and overall life satisfaction. We used thorough statistical methods to compare the results between the two groups.
The findings indicated that MOMH is both effective and safe for individuals dealing with NLC. Participants reported improvements in their symptoms, demonstrating that this magnesium supplement can play a helpful role in managing nocturnal leg cramps.
Read More
9
We sought to understand the effectiveness of oral magnesium in treating leg cramps experienced by pregnant women. Our study was well-structured, involving a double-blind, randomized, placebo-controlled design. It included 86 healthy pregnant women between 14 to 34 weeks of gestation who encountered leg cramps at least twice a week, and we followed them over a four-week period.
At the end of the study, we discovered that the women taking magnesium bisglycinate chelate (300 mg per day) reported a significant reduction in cramp frequency—86% experienced at least a 50% drop compared to only 60.5% of those taking the placebo. Additionally, those on magnesium also noted a notable decrease in cramp intensity, with 69.8% achieving a similar improvement versus just 48.8% in the placebo group.
Encouragingly, we found no major side effects reported in either group, such as nausea or diarrhea. Our findings suggest that magnesium supplements can effectively reduce both the frequency and severity of leg cramps during pregnancy, offering a potential treatment option for women dealing with this common issue.
At the end of the study, we discovered that the women taking magnesium bisglycinate chelate (300 mg per day) reported a significant reduction in cramp frequency—86% experienced at least a 50% drop compared to only 60.5% of those taking the placebo. Additionally, those on magnesium also noted a notable decrease in cramp intensity, with 69.8% achieving a similar improvement versus just 48.8% in the placebo group.
Encouragingly, we found no major side effects reported in either group, such as nausea or diarrhea. Our findings suggest that magnesium supplements can effectively reduce both the frequency and severity of leg cramps during pregnancy, offering a potential treatment option for women dealing with this common issue.
Read More
7
We set out to investigate whether magnesium citrate could be an effective remedy for those who experience bothersome leg cramps, particularly at night. In our study, we used a randomised, double-blind, cross-over, placebo-controlled design to ensure reliable results. Participants suffering from regular leg cramps were recruited and given either magnesium citrate or a matching placebo over six weeks.
Our findings revealed that those who began the trial with the placebo experienced an average reduction in cramps when taking magnesium, with a median of 5 cramps compared to 9 on the placebo. Moreover, a notable percentage of participants felt that the magnesium treatment had indeed helped them, with 78% reporting benefits, as opposed to 54% who felt the placebo was effective.
While these results suggest that magnesium may have a positive impact, it’s essential to mention that the impact on cramp severity and duration wasn’t significantly different between the two groups. Additionally, some participants did report experiencing diarrhoea as a side effect of magnesium. Overall, we believe magnesium shows promise in alleviating nocturnal leg cramps and recommend further research to fully evaluate its effectiveness.
Our findings revealed that those who began the trial with the placebo experienced an average reduction in cramps when taking magnesium, with a median of 5 cramps compared to 9 on the placebo. Moreover, a notable percentage of participants felt that the magnesium treatment had indeed helped them, with 78% reporting benefits, as opposed to 54% who felt the placebo was effective.
While these results suggest that magnesium may have a positive impact, it’s essential to mention that the impact on cramp severity and duration wasn’t significantly different between the two groups. Additionally, some participants did report experiencing diarrhoea as a side effect of magnesium. Overall, we believe magnesium shows promise in alleviating nocturnal leg cramps and recommend further research to fully evaluate its effectiveness.
Read More
7
Magnesium shows potential benefits
We explored the effectiveness of magnesium treatment for leg cramps during pregnancy through a review of five randomized trials involving 352 women.
The trials varied in quality, but interestingly, they included comparisons of different treatments such as calcium and sodium chloride against placebos. While the placebo-controlled trial that investigated calcium did not show any significant benefits, there were hints of promise for magnesium.
For those looking for relief from troublesome leg cramps, our analysis indicated that magnesium—specifically in the forms of magnesium lactate or citrate—might help. Taking 5mmol in the morning and 10mmol in the evening seemed to provide the best results.
However, the evidence remains mixed, and we couldn't pinpoint any strong benefits from other combinations or supplements tested. So, while magnesium might be beneficial, it’s essential to approach it as one option among many.
The trials varied in quality, but interestingly, they included comparisons of different treatments such as calcium and sodium chloride against placebos. While the placebo-controlled trial that investigated calcium did not show any significant benefits, there were hints of promise for magnesium.
For those looking for relief from troublesome leg cramps, our analysis indicated that magnesium—specifically in the forms of magnesium lactate or citrate—might help. Taking 5mmol in the morning and 10mmol in the evening seemed to provide the best results.
However, the evidence remains mixed, and we couldn't pinpoint any strong benefits from other combinations or supplements tested. So, while magnesium might be beneficial, it’s essential to approach it as one option among many.
Read More
User Reviews
USERS' SCORE
Good
Based on 115 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9
Supports muscular system
143 people found this helpful
Very good quality magnesium. My husband takes it as recommended by his doctor. He takes three tablets daily, and it supports his muscle system effectively. His nocturnal leg cramps and twitching have disappeared while benefiting his heart.
Read More
7.5
Overall wellbeing improved
122 people found this helpful
One of the best magnesium supplements! It works splendidly, particularly when paired with vitamin B6. It effectively tackled my night cramps linked to magnesium deficiency. I've noticed an improvement in my overall emotional state as well.
Read More
9
Increased morning energy
105 people found this helpful
Great magnesium! I take two capsules daily after breakfast. It has eradicated my leg cramps, boosted my energy, and made waking up in the morning much easier. My nerves feel less strained too.
Read More
9
Calms leg cramps
42 people found this helpful
I tried different versions of magnesium, and this one is perfect for a sensitive stomach. It has no laxative effect and helps with nocturnal cramps in my legs. The pills are medium-sized, easy to swallow, and have a slight sweetness. They effectively fulfil their purpose. While on the KETO diet, I take three daily and find I wake up more refreshed. After a month, my blood tests showed excellent absorption levels. I plan to buy this again!
Read More
10
Cramps lessened
29 people found this helpful
After a week of taking these for my fibromyalgia and restless leg syndrome, I've noticed a huge difference. I've reduced my cramps significantly and am grateful for the larger bottle. Continual use has shown positive results, keeping cramps at bay.
Read More
Frequently Asked Questions
9
Leg cramps relief
8 people found this helpful
I like this. An excellent medication, after a week of taking it, I slept soundly and my legs did not cramp. I recommend it.
9
Obvious effect
6 people found this helpful
Typically, the effects of dietary supplements are subtle, but after a week of magnesium use, my sleep improved significantly, leg cramps ceased, and twitching eyes were no longer an issue. I will keep it in my first-aid kit due to its clear benefits.
10
Eliminated leg pain
10 people found this helpful
After three months of taking Sourse Naturals Magnesium Malate, my anxiety has greatly decreased, and I now sleep soundly without muscle spasms or leg pain. I also experience fewer headaches, which has been a substantial benefit of magnesium.
10
No more cramps
2 people found this helpful
The best! I discovered this product 9 years ago when I started keto; magnesium is vital for any diet. I work out and need it for muscle recovery. My husband, who gets terrible leg cramps and restless legs, took it on his doctor’s advice. Within 2 days, his leg cramps disappeared. If he misses a dose, they'll return in 24-48 hours. Best product and quality, although the pills are quite large.
9
Cramps nearly gone
5 people found this helpful
I’ve been using this product for leg cramps, having suffered severe cramps nightly for five years post-injury. A coach suggested Magnesium Malate, and now with foam rolling, my cramps have nearly vanished. Previously, I had multiple cramps nightly; now I experience maybe one or two very short ones monthly. My family members have also noticed significant improvements in their leg cramps with this product.
9
Cramps stopped
22 people found this helpful
Everyone should take magnesium regularly, especially parents and those under stress. I’ve found that it improves my sleep significantly, reduces leg cramps, and alleviates my eye twitching.
7.5
Overall wellbeing improved
122 people found this helpful
One of the best magnesium supplements! It works splendidly, particularly when paired with vitamin B6. It effectively tackled my night cramps linked to magnesium deficiency. I've noticed an improvement in my overall emotional state as well.
9
Effective for cramps
5 people found this helpful
Magnesium Malate is the only supplement I’ve found that effectively addresses cramps and supports heart health. A researcher noted that, regarding magnesium products available over the counter, "one would be better off eating a handful of dirt." The Malic Acid in this product aids absorption significantly within the small intestine. The potency of these tablets ensures that even older individuals with absorption issues like myself find relief. Magnesium is key to balancing electrolytes that, when unbalanced, cause painful leg cramps. This supplement has also helped with my Paroxysmal Atrial Fibrillation. I previously endured months of crippling cramps, but now, thanks to my research and determination, I’ve found lasting relief by taking 6 tablets daily.
9
Soothes cramps
8 people found this helpful
I initially ordered a taurine supplement but switched to magnesium malate when unavailable. After closely examining the ingredients, I tried this and felt a significant soothing effect. It effectively addresses leg muscle cramps and supports joint health. I wholeheartedly recommend this product, which has a neutral taste and comes in a large package.
9
Supports muscular system
143 people found this helpful
Very good quality magnesium. My husband takes it as recommended by his doctor. He takes three tablets daily, and it supports his muscle system effectively. His nocturnal leg cramps and twitching have disappeared while benefiting his heart.
9
Increased morning energy
105 people found this helpful
Great magnesium! I take two capsules daily after breakfast. It has eradicated my leg cramps, boosted my energy, and made waking up in the morning much easier. My nerves feel less strained too.
10
Cramp relief
3 people found this helpful
I regularly consume this excellent magnesium. I used to suffer from many night cramps in my calf muscles, but since taking magnesium, they've disappeared, and I’ve been sleeping better. I recommend about 400 mg daily.
9
Magnesium oxide treats leg cramps
We conducted a study to evaluate how effective magnesium oxide monohydrate (MOMH) is in treating nocturnal leg cramps (NLC). This was a randomized, double-blind, placebo-controlled trial involving multiple centers in Ukraine, where participants took either MOMH or a placebo nightly for 60 days.
Our focus was on measuring the frequency and duration of cramps, the pain they caused, and how they affected sleep quality and overall life satisfaction. We used thorough statistical methods to compare the results between the two groups.
The findings indicated that MOMH is both effective and safe for individuals dealing with NLC. Participants reported improvements in their symptoms, demonstrating that this magnesium supplement can play a helpful role in managing nocturnal leg cramps.
Our focus was on measuring the frequency and duration of cramps, the pain they caused, and how they affected sleep quality and overall life satisfaction. We used thorough statistical methods to compare the results between the two groups.
The findings indicated that MOMH is both effective and safe for individuals dealing with NLC. Participants reported improvements in their symptoms, demonstrating that this magnesium supplement can play a helpful role in managing nocturnal leg cramps.
2
We examined the effectiveness of magnesium supplements in reducing leg cramps during pregnancy, a common issue that affects up to half of pregnant women. Four randomized controlled trials were included in our analysis, with a total of 332 participants, which compared magnesium treatment to a placebo.
Our findings showed that magnesium supplementation did not significantly decrease the frequency of leg cramps compared to the control group. The weighted mean difference was -0.47, which indicates that while there may be a slight improvement, it was not considered statistically meaningful.
Moreover, magnesium did not help women recover from leg cramps more effectively than the placebo, and there were no significant side effects reported. Overall, we found that oral magnesium supplementation is not effective in treating leg cramps during pregnancy.
Our findings showed that magnesium supplementation did not significantly decrease the frequency of leg cramps compared to the control group. The weighted mean difference was -0.47, which indicates that while there may be a slight improvement, it was not considered statistically meaningful.
Moreover, magnesium did not help women recover from leg cramps more effectively than the placebo, and there were no significant side effects reported. Overall, we found that oral magnesium supplementation is not effective in treating leg cramps during pregnancy.
2
We investigated the effectiveness of oral magnesium supplementation in reducing leg cramps among pregnant women. In a controlled clinical trial with 132 participants, we compared the impact of 300 mg/day of magnesium citrate against a placebo.
Most participants experienced multiple leg cramps each week, and after four weeks, we recorded a notable reduction in leg cramps overall—28.4% across all women. However, when looking closely, we found no significant difference between the magnesium group and the placebo group. The placebo group even reported a slightly higher percentage of reduction in cramps (32.8% versus 27.2% for magnesium).
We also looked at the side effects and found that four women reported mild gastrointestinal issues, but these were not serious. Overall, the results suggest that oral magnesium supplementation does not significantly improve leg cramps during pregnancy, raising questions about its effectiveness for this purpose.
Most participants experienced multiple leg cramps each week, and after four weeks, we recorded a notable reduction in leg cramps overall—28.4% across all women. However, when looking closely, we found no significant difference between the magnesium group and the placebo group. The placebo group even reported a slightly higher percentage of reduction in cramps (32.8% versus 27.2% for magnesium).
We also looked at the side effects and found that four women reported mild gastrointestinal issues, but these were not serious. Overall, the results suggest that oral magnesium supplementation does not significantly improve leg cramps during pregnancy, raising questions about its effectiveness for this purpose.
4
We explored how magnesium might help alleviate leg cramps during pregnancy through a systematic review of six randomized controlled trials, involving 390 women in total. These studies compared magnesium with placebo or no treatment to see if it could reduce the frequency and intensity of these cramps.
Interestingly, the results showed mixed outcomes. While some trials indicated a slight reduction in the number of leg cramps after magnesium treatment, it wasn't consistent across the board. For example, one trial noted that magnesium could lead to a 50% reduction in cramps, while others found no significant difference compared to placebo.
We also observed that the overall quality of the evidence was low, mainly due to small sample sizes and design limitations. The studies did not comprehensively assess the safety of magnesium either, as side effects were only reported for magnesium versus placebo. Additionally, it was worth noting that other interventions like calcium and vitamin B were also tested but did not show a clear advantage over magnesium.
In conclusion, our findings leave us with an unclear picture of magnesium's effectiveness against leg cramps in pregnant women. For a more definitive answer, more rigorous studies are warranted, especially those exploring different methodologies, including non-drug therapies.
Interestingly, the results showed mixed outcomes. While some trials indicated a slight reduction in the number of leg cramps after magnesium treatment, it wasn't consistent across the board. For example, one trial noted that magnesium could lead to a 50% reduction in cramps, while others found no significant difference compared to placebo.
We also observed that the overall quality of the evidence was low, mainly due to small sample sizes and design limitations. The studies did not comprehensively assess the safety of magnesium either, as side effects were only reported for magnesium versus placebo. Additionally, it was worth noting that other interventions like calcium and vitamin B were also tested but did not show a clear advantage over magnesium.
In conclusion, our findings leave us with an unclear picture of magnesium's effectiveness against leg cramps in pregnant women. For a more definitive answer, more rigorous studies are warranted, especially those exploring different methodologies, including non-drug therapies.
7
Magnesium shows potential benefits
We explored the effectiveness of magnesium treatment for leg cramps during pregnancy through a review of five randomized trials involving 352 women.
The trials varied in quality, but interestingly, they included comparisons of different treatments such as calcium and sodium chloride against placebos. While the placebo-controlled trial that investigated calcium did not show any significant benefits, there were hints of promise for magnesium.
For those looking for relief from troublesome leg cramps, our analysis indicated that magnesium—specifically in the forms of magnesium lactate or citrate—might help. Taking 5mmol in the morning and 10mmol in the evening seemed to provide the best results.
However, the evidence remains mixed, and we couldn't pinpoint any strong benefits from other combinations or supplements tested. So, while magnesium might be beneficial, it’s essential to approach it as one option among many.
The trials varied in quality, but interestingly, they included comparisons of different treatments such as calcium and sodium chloride against placebos. While the placebo-controlled trial that investigated calcium did not show any significant benefits, there were hints of promise for magnesium.
For those looking for relief from troublesome leg cramps, our analysis indicated that magnesium—specifically in the forms of magnesium lactate or citrate—might help. Taking 5mmol in the morning and 10mmol in the evening seemed to provide the best results.
However, the evidence remains mixed, and we couldn't pinpoint any strong benefits from other combinations or supplements tested. So, while magnesium might be beneficial, it’s essential to approach it as one option among many.
References
- Barna O, Lohoida P, Holovchenko Y, Bazylevych A, Velychko V, et al. A randomized, double-blind, placebo-controlled, multicenter study assessing the efficacy of magnesium oxide monohydrate in the treatment of nocturnal leg cramps. Nutr J. 2021;20:90. doi:10.1186/s12937-021-00747-9
- Liu J, Song G, Zhao G, Meng T. Effect of oral magnesium supplementation for relieving leg cramps during pregnancy: A meta-analysis of randomized controlled trials. Taiwan J Obstet Gynecol. 2021;60:609. doi:10.1016/j.tjog.2021.05.006
- Luo L, Zhou K, Zhang J, Xu L, Yin W. Interventions for leg cramps in pregnancy. Cochrane Database Syst Rev. 2020;12:CD010655. doi:10.1002/14651858.CD010655.pub3
- Garrison SR, Korownyk CS, Kolber MR, Allan GM, Musini VM, et al. Magnesium for skeletal muscle cramps. Cochrane Database Syst Rev. 2020;9:CD009402. doi:10.1002/14651858.CD009402.pub3
- Araújo CAL, Lorena SB, Cavalcanti GCS, Leão GLS, Tenório GP, et al. Oral magnesium supplementation for leg cramps in pregnancy-An observational controlled trial. PLoS One. 2020;15:e0227497. doi:10.1371/journal.pone.0227497
- Sebo P, Haller D, Cerutti B, Maisonneuve H. A prospective observational study of the main features of nocturnal leg cramps in primary care. Swiss Med Wkly. 2019;149:w20048. doi:10.4414/smw.2019.20048
- Roguin Maor N, Alperin M, Shturman E, Khairaldeen H, Friedman M, et al. Effect of Magnesium Oxide Supplementation on Nocturnal Leg Cramps: A Randomized Clinical Trial. JAMA Intern Med. 2017;177:617. doi:10.1001/jamainternmed.2016.9261
- Zhou K, West HM, Zhang J, Xu L, Li W. Interventions for leg cramps in pregnancy. Cochrane Database Syst Rev. 2015. doi:10.1002/14651858.CD010655.pub2
- Sebo P, Cerutti B, Haller DM. Effect of magnesium therapy on nocturnal leg cramps: a systematic review of randomized controlled trials with meta-analysis using simulations. Fam Pract. 2014;31:7. doi:10.1093/fampra/cmt065
- Garrison SR, Allan GM, Sekhon RK, Musini VM, Khan KM. Magnesium for skeletal muscle cramps. Cochrane Database Syst Rev. 2012;2012:CD009402. doi:10.1002/14651858.CD009402.pub2
- Supakatisant C, Phupong V. Oral magnesium for relief in pregnancy-induced leg cramps: a randomised controlled trial. Matern Child Nutr. 2015;11:139. doi:10.1111/j.1740-8709.2012.00440.x
- Garrison SR, Birmingham CL, Koehler BE, McCollom RA, Khan KM. The effect of magnesium infusion on rest cramps: randomized controlled trial. J Gerontol A Biol Sci Med Sci. 2011;66:661. doi:10.1093/gerona/glq232
- Uña E. Atypical presentation of acute neurotoxicity secondary to oxaliplatin. J Oncol Pharm Pract. 2010;16:280. doi:10.1177/1078155209355849
- Roffe C, Sills S, Crome P, Jones P. Randomised, cross-over, placebo controlled trial of magnesium citrate in the treatment of chronic persistent leg cramps. Med Sci Monit. 2002;8:CR326.
- Young GL, Jewell D. Interventions for leg cramps in pregnancy. Cochrane Database Syst Rev. 2002.
- Frusso R, Zárate M, Augustovski F, Rubinstein A. Magnesium for the treatment of nocturnal leg cramps: a crossover randomized trial. J Fam Pract. 1999;48:868.
- Dahle LO, Berg G, Hammar M, Hurtig M, Larsson L. The effect of oral magnesium substitution on pregnancy-induced leg cramps. Am J Obstet Gynecol. 1995;173:175.
