' 
SCIENTIFIC SCORE
Possibly Effective
Based on 25 Researches
7.6
USERS' SCORE
Good
Based on 47 Reviews
8.7
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
15
Total Fat
1.5 g
2%**
Wild Caught Fish Oil Concentrate
1250 mg
†
Total Omega-3 Fatty Acids as TG
1055 mg
†
EPA (Eicosapentaenoic Acid)
690 mg
†
DHA (Docosahexaenoic Acid)
310 mg
†
Other Omega-3 Fatty Acids
55 mg
†
Top Medical Research Studies
9
Eicosapentaenoic acid influences clotting
Emergence of omega-3 fatty acids in biomedical research.
Moderate interest from study findings
We explored how eicosapentaenoic acid (EPA), a type of omega-3 fatty acid, influences blood clotting processes. The interest in EPA grew substantially after the 1970s when researchers Dyerberg and Bang noted that Greenland Eskimos had lower rates of coronary disease linked to their diet rich in marine lipids.
Their findings suggested that the higher levels of EPA led to reduced platelet aggregation, which essentially means that the blood clots less easily. This anti-clotting effect is significant since blood clots can lead to serious health issues like heart attacks and strokes.
Although studies have shown these promising effects, it’s crucial to note that much of the initial acclaim came from dietary observations rather than controlled clinical trials. This means that while we can relate high EPA intake to lower health risks in specific populations, we still need more rigorous studies to fully understand the impact of EPA on blood clotting across diverse groups.
Their findings suggested that the higher levels of EPA led to reduced platelet aggregation, which essentially means that the blood clots less easily. This anti-clotting effect is significant since blood clots can lead to serious health issues like heart attacks and strokes.
Although studies have shown these promising effects, it’s crucial to note that much of the initial acclaim came from dietary observations rather than controlled clinical trials. This means that while we can relate high EPA intake to lower health risks in specific populations, we still need more rigorous studies to fully understand the impact of EPA on blood clotting across diverse groups.
Read More
9
EPA's impact on blood clotting
Acute coronary syndrome remodels the antiplatelet aggregation properties of HDL particle subclasses.
Significant blood clot treatment insights
We explored the effects of eicosapentaenoic acid (EPA), particularly in the context of acute coronary syndrome (ACS), on blood clotting. The study highlighted how different subclasses of high-density lipoprotein (HDL), particularly HDL2 from ACS patients, interact with platelets during clot formation.
It became clear that HDL2 from ACS patients exhibited a stronger ability to inhibit platelet aggregation compared to HDL from healthy individuals. This ability to reduce clot formation is linked to the presence of specific oxidized polyunsaturated fatty acids in the HDL2 particles.
We observed an inverse relationship between several oxidized fatty acids, such as 18-hydroxyeicosapentaenoic acid (18-HEPE) and others, and platelet aggregation. This means that higher levels of these oxidized fats were associated with less platelet activation and clotting, pointing to their potential role in enhancing the antithrombotic properties of HDL2 in ACS patients.
Overall, the findings suggest that EPA and its oxidized metabolites could play a key role in modifying HDL properties, thereby offering some protection against blood clots in individuals with ACS.
It became clear that HDL2 from ACS patients exhibited a stronger ability to inhibit platelet aggregation compared to HDL from healthy individuals. This ability to reduce clot formation is linked to the presence of specific oxidized polyunsaturated fatty acids in the HDL2 particles.
We observed an inverse relationship between several oxidized fatty acids, such as 18-hydroxyeicosapentaenoic acid (18-HEPE) and others, and platelet aggregation. This means that higher levels of these oxidized fats were associated with less platelet activation and clotting, pointing to their potential role in enhancing the antithrombotic properties of HDL2 in ACS patients.
Overall, the findings suggest that EPA and its oxidized metabolites could play a key role in modifying HDL properties, thereby offering some protection against blood clots in individuals with ACS.
Read More
8
Omega-3s reduce blood clotting
Omega-3 Fatty Acids and Markers of Thrombosis in Patients with Atrial Fibrillation.
Significant findings on thrombotic markers
We explored how omega-3 fatty acids, particularly eicosapentaenoic acid (EPA), influence blood clot markers in patients with atrial fibrillation (AF). Our research involved a large group of 2,373 patients, assessing the levels of D-dimer and beta-thromboglobulin (BTG), which are indicators of blood clotting activity and platelet activation.
The results showed that higher total omega-3 fatty acid levels were linked to lower D-dimer and BTG levels, which suggests a potential antithrombotic effect. Notably, the individual omega-3s, including EPA, docosahexaenoic acid (DHA), and others, generally displayed similar associations.
While EPA had a small positive relationship with BTG, DHA, DPA, and ALA were associated with lower BTG levels, indicating varied effects among these fatty acids. Overall, we found that increased omega-3 fatty acid levels could contribute to reduced activation of blood clotting mechanisms in patients with AF, highlighting the potential benefits of omega-3 intake for cardiovascular health.
The results showed that higher total omega-3 fatty acid levels were linked to lower D-dimer and BTG levels, which suggests a potential antithrombotic effect. Notably, the individual omega-3s, including EPA, docosahexaenoic acid (DHA), and others, generally displayed similar associations.
While EPA had a small positive relationship with BTG, DHA, DPA, and ALA were associated with lower BTG levels, indicating varied effects among these fatty acids. Overall, we found that increased omega-3 fatty acid levels could contribute to reduced activation of blood clotting mechanisms in patients with AF, highlighting the potential benefits of omega-3 intake for cardiovascular health.
Read More
Most Useful Reviews
9.5
Skin condition improved
The ideal dosage for everyday vitamins comes in a plastic jar with protective mica on the lid. The sleek black design conveys quality. The capsules are large, dense, and rich golden colour, with no smell, which delighted me! They swallow easily with a glass of water, and I don’t feel them in my throat. No fishy burps or unpleasant aftertastes! I track my skin condition, especially dryness on my elbows and legs. Without omega, my skin stays dry, needing constant moisturising. With omega, my skin feels normal, soft, and delicate. I can't identify its effects on heart health or blood vessels, but I do maintain good blood pressure for my age.
Read More
9.5
Less eye fatigue
These vitamins in a plastic jar with a mica lid caught my attention. I was struck by the sleek design, giving it a quality appearance. The large golden capsules are easy to swallow with water, and I've not experienced any unpleasant aftertaste or fishy burps after taking them. Since starting omega, the dry skin on my elbows and legs is no longer an issue; my skin feels soft and smooth. While I can't specifically judge its impact on my heart or joints, my blood pressure remains stable, which is normal for me. Additionally, I've noticed my eyes feel less tired during the day.
Read More
9.5
Improved skin quality
The ideal dosage for daily vitamins comes in a plastic jar with protective mica on the lid, which I removed initially. The strict black design makes the dietary supplement look presentable and gives an impression of quality. The capsules are large, dense, and a rich golden colour, with no smell, which made me very happy! It swallows well with a glass of water without feeling stuck in my throat, and there's no fishy burp or aftertaste. My skin, which was dry and required moisturising creams without omega, has become soft and delicate with its reception. I haven’t noted its effect on the heart, blood vessels, or joints, except for maintaining good blood pressure appropriate for my age. My vision has improved, as my eyes feel less tired.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 25 Researches
7.6
- All Researches
9
Eicosapentaenoic acid influences clotting
Emergence of omega-3 fatty acids in biomedical research.
Moderate interest from study findings
We explored how eicosapentaenoic acid (EPA), a type of omega-3 fatty acid, influences blood clotting processes. The interest in EPA grew substantially after the 1970s when researchers Dyerberg and Bang noted that Greenland Eskimos had lower rates of coronary disease linked to their diet rich in marine lipids.
Their findings suggested that the higher levels of EPA led to reduced platelet aggregation, which essentially means that the blood clots less easily. This anti-clotting effect is significant since blood clots can lead to serious health issues like heart attacks and strokes.
Although studies have shown these promising effects, it’s crucial to note that much of the initial acclaim came from dietary observations rather than controlled clinical trials. This means that while we can relate high EPA intake to lower health risks in specific populations, we still need more rigorous studies to fully understand the impact of EPA on blood clotting across diverse groups.
Their findings suggested that the higher levels of EPA led to reduced platelet aggregation, which essentially means that the blood clots less easily. This anti-clotting effect is significant since blood clots can lead to serious health issues like heart attacks and strokes.
Although studies have shown these promising effects, it’s crucial to note that much of the initial acclaim came from dietary observations rather than controlled clinical trials. This means that while we can relate high EPA intake to lower health risks in specific populations, we still need more rigorous studies to fully understand the impact of EPA on blood clotting across diverse groups.
Read More
9
EPA's impact on blood clotting
Acute coronary syndrome remodels the antiplatelet aggregation properties of HDL particle subclasses.
Significant blood clot treatment insights
We explored the effects of eicosapentaenoic acid (EPA), particularly in the context of acute coronary syndrome (ACS), on blood clotting. The study highlighted how different subclasses of high-density lipoprotein (HDL), particularly HDL2 from ACS patients, interact with platelets during clot formation.
It became clear that HDL2 from ACS patients exhibited a stronger ability to inhibit platelet aggregation compared to HDL from healthy individuals. This ability to reduce clot formation is linked to the presence of specific oxidized polyunsaturated fatty acids in the HDL2 particles.
We observed an inverse relationship between several oxidized fatty acids, such as 18-hydroxyeicosapentaenoic acid (18-HEPE) and others, and platelet aggregation. This means that higher levels of these oxidized fats were associated with less platelet activation and clotting, pointing to their potential role in enhancing the antithrombotic properties of HDL2 in ACS patients.
Overall, the findings suggest that EPA and its oxidized metabolites could play a key role in modifying HDL properties, thereby offering some protection against blood clots in individuals with ACS.
It became clear that HDL2 from ACS patients exhibited a stronger ability to inhibit platelet aggregation compared to HDL from healthy individuals. This ability to reduce clot formation is linked to the presence of specific oxidized polyunsaturated fatty acids in the HDL2 particles.
We observed an inverse relationship between several oxidized fatty acids, such as 18-hydroxyeicosapentaenoic acid (18-HEPE) and others, and platelet aggregation. This means that higher levels of these oxidized fats were associated with less platelet activation and clotting, pointing to their potential role in enhancing the antithrombotic properties of HDL2 in ACS patients.
Overall, the findings suggest that EPA and its oxidized metabolites could play a key role in modifying HDL properties, thereby offering some protection against blood clots in individuals with ACS.
Read More
9
Fish oil may reduce clotting risk
Relation of fish oil supplementation to markers of atherothrombotic risk in patients with cardiovascular disease not receiving lipid-lowering therapy.
Study shows potential benefits
We explored the effects of eicosapentaenoic acid (EPA) found in fish oil supplements on the risk of blood clotting in patients with suspected coronary artery disease who weren’t taking lipid-lowering medications. The study included 600 consecutive patients, and we compared those taking fish oil to those who weren’t.
Our findings showed that fish oil supplementation was associated with beneficial changes in several cholesterol levels, particularly lower levels of very low-density lipoprotein (VLDL) and intermediate-density lipoprotein (IDL) cholesterol. This aligns with evidence that EPA could play a role in heart health.
Notably, patients who took fish oil demonstrated reduced platelet aggregation and lower levels of urinary thromboxane B2, a marker associated with blood clot formation. This suggests that fish oil could potentially help in lowering atherothrombotic risk, especially for those not on other cholesterol-lowering treatments.
While the results are promising, further studies are warranted to confirm these findings and better understand the independent effects of EPA on blood clotting.
Our findings showed that fish oil supplementation was associated with beneficial changes in several cholesterol levels, particularly lower levels of very low-density lipoprotein (VLDL) and intermediate-density lipoprotein (IDL) cholesterol. This aligns with evidence that EPA could play a role in heart health.
Notably, patients who took fish oil demonstrated reduced platelet aggregation and lower levels of urinary thromboxane B2, a marker associated with blood clot formation. This suggests that fish oil could potentially help in lowering atherothrombotic risk, especially for those not on other cholesterol-lowering treatments.
While the results are promising, further studies are warranted to confirm these findings and better understand the independent effects of EPA on blood clotting.
Read More
8
Omega-3s reduce blood clotting
Omega-3 Fatty Acids and Markers of Thrombosis in Patients with Atrial Fibrillation.
Significant findings on thrombotic markers
We explored how omega-3 fatty acids, particularly eicosapentaenoic acid (EPA), influence blood clot markers in patients with atrial fibrillation (AF). Our research involved a large group of 2,373 patients, assessing the levels of D-dimer and beta-thromboglobulin (BTG), which are indicators of blood clotting activity and platelet activation.
The results showed that higher total omega-3 fatty acid levels were linked to lower D-dimer and BTG levels, which suggests a potential antithrombotic effect. Notably, the individual omega-3s, including EPA, docosahexaenoic acid (DHA), and others, generally displayed similar associations.
While EPA had a small positive relationship with BTG, DHA, DPA, and ALA were associated with lower BTG levels, indicating varied effects among these fatty acids. Overall, we found that increased omega-3 fatty acid levels could contribute to reduced activation of blood clotting mechanisms in patients with AF, highlighting the potential benefits of omega-3 intake for cardiovascular health.
The results showed that higher total omega-3 fatty acid levels were linked to lower D-dimer and BTG levels, which suggests a potential antithrombotic effect. Notably, the individual omega-3s, including EPA, docosahexaenoic acid (DHA), and others, generally displayed similar associations.
While EPA had a small positive relationship with BTG, DHA, DPA, and ALA were associated with lower BTG levels, indicating varied effects among these fatty acids. Overall, we found that increased omega-3 fatty acid levels could contribute to reduced activation of blood clotting mechanisms in patients with AF, highlighting the potential benefits of omega-3 intake for cardiovascular health.
Read More
8
Fatty acids' mixed effects on VTE
Plasma Phospholipid Fatty Acids and Risk of Venous Thromboembolism: Mendelian Randomization Investigation.
Mixed relevance; not primarily focused
We explored how fatty acids, specifically eicosapentaenoic acid (EPA), relate to the risk of blood clots known as venous thromboembolism (VTE). Through a Mendelian randomization study, we examined genetic variants linked to ten fatty acids sourced from large participant groups, including over 30,000 VTE cases.
Our findings revealed that for every standard deviation increase in genetically predicted levels of eicosapentaenoic acid, the odds of developing VTE increased by 16%. This indicates a potential risk factor associated with EPA rather than a beneficial effect.
Interestingly, while other fatty acids, like oleic and linoleic acids, were linked to a decrease in VTE risk, EPA did not show a protective benefit. It's essential to consider these varying effects when thinking about dietary modifications for blood clot prevention. In summary, while some fatty acids may help reduce the risk of blood clots, eicosapentaenoic acid appears to be associated with an increased risk instead.
Our findings revealed that for every standard deviation increase in genetically predicted levels of eicosapentaenoic acid, the odds of developing VTE increased by 16%. This indicates a potential risk factor associated with EPA rather than a beneficial effect.
Interestingly, while other fatty acids, like oleic and linoleic acids, were linked to a decrease in VTE risk, EPA did not show a protective benefit. It's essential to consider these varying effects when thinking about dietary modifications for blood clot prevention. In summary, while some fatty acids may help reduce the risk of blood clots, eicosapentaenoic acid appears to be associated with an increased risk instead.
Read More
User Reviews
USERS' SCORE
Good
Based on 47 Reviews
8.7
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Skin condition improved
The ideal dosage for everyday vitamins comes in a plastic jar with protective mica on the lid. The sleek black design conveys quality. The capsules are large, dense, and rich golden colour, with no smell, which delighted me! They swallow easily with a glass of water, and I don’t feel them in my throat. No fishy burps or unpleasant aftertastes! I track my skin condition, especially dryness on my elbows and legs. Without omega, my skin stays dry, needing constant moisturising. With omega, my skin feels normal, soft, and delicate. I can't identify its effects on heart health or blood vessels, but I do maintain good blood pressure for my age.
Read More
9.5
Less eye fatigue
These vitamins in a plastic jar with a mica lid caught my attention. I was struck by the sleek design, giving it a quality appearance. The large golden capsules are easy to swallow with water, and I've not experienced any unpleasant aftertaste or fishy burps after taking them. Since starting omega, the dry skin on my elbows and legs is no longer an issue; my skin feels soft and smooth. While I can't specifically judge its impact on my heart or joints, my blood pressure remains stable, which is normal for me. Additionally, I've noticed my eyes feel less tired during the day.
Read More
9.5
Improved skin quality
The ideal dosage for daily vitamins comes in a plastic jar with protective mica on the lid, which I removed initially. The strict black design makes the dietary supplement look presentable and gives an impression of quality. The capsules are large, dense, and a rich golden colour, with no smell, which made me very happy! It swallows well with a glass of water without feeling stuck in my throat, and there's no fishy burp or aftertaste. My skin, which was dry and required moisturising creams without omega, has become soft and delicate with its reception. I haven’t noted its effect on the heart, blood vessels, or joints, except for maintaining good blood pressure appropriate for my age. My vision has improved, as my eyes feel less tired.
Read More
9.5
Vision fatigue reduced
The ideal daily vitamin dosage is packaged in a plastic jar with protective mica on the lid, which I removed at the first inspection. The black design gives it a quality appearance. The large, dense capsules are rich golden colour and odourless, which pleased me! They swallow easily with water, and even though they're large, there's no feeling of obstruction in my throat. I haven’t experienced any fishy burps or unpleasant tastes! I monitor the results of taking it, particularly with my dry skin on the elbows and legs. Without omega, my skin is uncomfortably dry, but with omega, it’s soft and manageable. While I cannot comment on the impacts on my heart or blood vessels, I experience good, consistent blood pressure for my age, and I've noticed my eyesight feels less strained.
Read More
8.5
Stable blood pressure
I appreciate the vitamins I found in a smart black jar with a mica lid. The capsules have a rich golden colour and are easy to swallow comfortably without objectionable flavours or aftertastes. The impact on my dry skin has been noteworthy, with omega making it smooth and soft instead of needing constant hydration. While I can't comment on the positives for my heart, blood vessels, and joints, aside from my reliably good blood pressure—normal for my age—I have certainly been delighted with a reduction in eye fatigue.
Read More
