Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.4
USERS' SCORE
Moderately Good
Based on 9 Reviews
7.1
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
15
Total Fat
1.5 g
2%**
Wild Caught Fish Oil Concentrate
1250 mg
†
Total Omega-3 Fatty Acids as TG
1055 mg
†
EPA (Eicosapentaenoic Acid)
690 mg
†
DHA (Docosahexaenoic Acid)
310 mg
†
Other Omega-3 Fatty Acids
55 mg
†
Top Medical Research Studies
9
We embarked on a study to find out how dietary eicosapentaenoic acid (EPA) could help children suffering from atopic dermatitis, a common form of eczema. In a randomized triple-blind clinical trial, 48 children with this condition were divided into two groups—one received 250 mg of EPA twice daily, while the other received a placebo for four weeks.
Our observations showed noticeable improvements in those who took EPA. After just two weeks, participants in the EPA group reported a reduction in their SCORAD scores, which are used to measure the severity of atopic dermatitis. The scores went down significantly compared to the placebo group. After four weeks, the number of children needing corticosteroids to manage their symptoms was also lower in the EPA group.
Despite these positive results, both groups reported few adverse effects, indicating that EPA supplementation is generally well-received. Overall, we conclude that adding EPA to the diet may be an effective and safe strategy for reducing eczema severity in children.
Our observations showed noticeable improvements in those who took EPA. After just two weeks, participants in the EPA group reported a reduction in their SCORAD scores, which are used to measure the severity of atopic dermatitis. The scores went down significantly compared to the placebo group. After four weeks, the number of children needing corticosteroids to manage their symptoms was also lower in the EPA group.
Despite these positive results, both groups reported few adverse effects, indicating that EPA supplementation is generally well-received. Overall, we conclude that adding EPA to the diet may be an effective and safe strategy for reducing eczema severity in children.
Read More
8
In a controlled trial, we assessed how docosahexaenoic acid (DHA)—an omega-3 fatty acid—affects atopic eczema. Fifty-three patients, aged 18 to 40, were randomly assigned to receive either 5.4 grams of DHA daily or an isoenergetic control comprising saturated fatty acids for eight weeks. This double-blind setup helped ensure that neither the participants nor the researchers knew who received which treatment, thereby reducing bias in the results.
Throughout the study, we measured the severity of eczema using the SCORAD index at multiple intervals. Our findings showed that DHA supplementation led to a notable improvement in eczema symptoms, with patients experiencing a significant decrease in their SCORAD scores. This contrasted with the control group, which did not show similar improvements. Notably, we also found that DHA reduced certain immune responses linked to eczema, indicating its potential role in managing this condition.
Given these encouraging results, it appears that DHA could be an effective dietary addition for people suffering from atopic eczema. However, further research with a larger participant pool is necessary to confirm these findings and fully understand the benefits of DHA on this skin condition.
Throughout the study, we measured the severity of eczema using the SCORAD index at multiple intervals. Our findings showed that DHA supplementation led to a notable improvement in eczema symptoms, with patients experiencing a significant decrease in their SCORAD scores. This contrasted with the control group, which did not show similar improvements. Notably, we also found that DHA reduced certain immune responses linked to eczema, indicating its potential role in managing this condition.
Given these encouraging results, it appears that DHA could be an effective dietary addition for people suffering from atopic eczema. However, further research with a larger participant pool is necessary to confirm these findings and fully understand the benefits of DHA on this skin condition.
Read More
9
Eicosapentaenoic acid improves eczema
We explored the effects of eicosapentaenoic acid (EPA) ethyl ester on symptoms of atopic dermatitis (AD), a common skin condition characterized by persistent itching and skin barrier dysfunction. In a carefully designed study using hairless mice on a special diet, we observed significant improvements in skin condition after administering EPA.
This study builds on previous findings that showed an increase in serum EPA levels from another omega-3 fatty acid, α-linolenic acid, which similarly helped restore skin health in mice with AD. When we administered EPA to the affected mice, we saw a marked alleviation in both itchy skin and barrier impairment.
A key finding was that the levels of covalently bound ceramides, essential lipids for maintaining our skin's barrier, were greatly reduced in the skin of the AD mice. With EPA treatment, these ceramides were restored, suggesting that EPA may play a crucial role in supporting skin health by improving these lipid levels.
Our findings point to the possible therapeutic application of EPA ethyl ester in treating human eczema, which could lead to effective new options for managing this often-challenging condition.
This study builds on previous findings that showed an increase in serum EPA levels from another omega-3 fatty acid, α-linolenic acid, which similarly helped restore skin health in mice with AD. When we administered EPA to the affected mice, we saw a marked alleviation in both itchy skin and barrier impairment.
A key finding was that the levels of covalently bound ceramides, essential lipids for maintaining our skin's barrier, were greatly reduced in the skin of the AD mice. With EPA treatment, these ceramides were restored, suggesting that EPA may play a crucial role in supporting skin health by improving these lipid levels.
Our findings point to the possible therapeutic application of EPA ethyl ester in treating human eczema, which could lead to effective new options for managing this often-challenging condition.
Read More
Most Useful Reviews
2
No relief noted
6 people found this helpful
Did not meet my expectations. I purchased this for its anti-inflammatory properties due to my eczema and allergies. Previously, other fish oils relieved my symptoms effectively, even at lower doses of omega-3. However, this product did nothing, despite its higher omega-3 content.
Read More
9
Eczema relief experienced
1 people found this helpful
This product helps with eczema.
Read More
9
Skin condition improved
After taking it for a month, I've seen significant effects. My eczema has improved, my skin feels more moisturised, and it exhibits anti-inflammatory properties.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.4
- All Researches
9
We embarked on a study to find out how dietary eicosapentaenoic acid (EPA) could help children suffering from atopic dermatitis, a common form of eczema. In a randomized triple-blind clinical trial, 48 children with this condition were divided into two groups—one received 250 mg of EPA twice daily, while the other received a placebo for four weeks.
Our observations showed noticeable improvements in those who took EPA. After just two weeks, participants in the EPA group reported a reduction in their SCORAD scores, which are used to measure the severity of atopic dermatitis. The scores went down significantly compared to the placebo group. After four weeks, the number of children needing corticosteroids to manage their symptoms was also lower in the EPA group.
Despite these positive results, both groups reported few adverse effects, indicating that EPA supplementation is generally well-received. Overall, we conclude that adding EPA to the diet may be an effective and safe strategy for reducing eczema severity in children.
Our observations showed noticeable improvements in those who took EPA. After just two weeks, participants in the EPA group reported a reduction in their SCORAD scores, which are used to measure the severity of atopic dermatitis. The scores went down significantly compared to the placebo group. After four weeks, the number of children needing corticosteroids to manage their symptoms was also lower in the EPA group.
Despite these positive results, both groups reported few adverse effects, indicating that EPA supplementation is generally well-received. Overall, we conclude that adding EPA to the diet may be an effective and safe strategy for reducing eczema severity in children.
Read More
9
Eicosapentaenoic acid improves eczema
We explored the effects of eicosapentaenoic acid (EPA) ethyl ester on symptoms of atopic dermatitis (AD), a common skin condition characterized by persistent itching and skin barrier dysfunction. In a carefully designed study using hairless mice on a special diet, we observed significant improvements in skin condition after administering EPA.
This study builds on previous findings that showed an increase in serum EPA levels from another omega-3 fatty acid, α-linolenic acid, which similarly helped restore skin health in mice with AD. When we administered EPA to the affected mice, we saw a marked alleviation in both itchy skin and barrier impairment.
A key finding was that the levels of covalently bound ceramides, essential lipids for maintaining our skin's barrier, were greatly reduced in the skin of the AD mice. With EPA treatment, these ceramides were restored, suggesting that EPA may play a crucial role in supporting skin health by improving these lipid levels.
Our findings point to the possible therapeutic application of EPA ethyl ester in treating human eczema, which could lead to effective new options for managing this often-challenging condition.
This study builds on previous findings that showed an increase in serum EPA levels from another omega-3 fatty acid, α-linolenic acid, which similarly helped restore skin health in mice with AD. When we administered EPA to the affected mice, we saw a marked alleviation in both itchy skin and barrier impairment.
A key finding was that the levels of covalently bound ceramides, essential lipids for maintaining our skin's barrier, were greatly reduced in the skin of the AD mice. With EPA treatment, these ceramides were restored, suggesting that EPA may play a crucial role in supporting skin health by improving these lipid levels.
Our findings point to the possible therapeutic application of EPA ethyl ester in treating human eczema, which could lead to effective new options for managing this often-challenging condition.
Read More
8
We aimed to explore the impact of dietary components on eczema, particularly focusing on docosahexaenoic acid (DHA). In our study, we induced skin inflammation in mice that were previously sensitized to allergens. While these mice were treated with food enriched with DHA and other ingredients, we closely observed any changes in their skin condition.
What we found was encouraging. The combination of DHA with arachidonic acid and non-digestible oligosaccharides significantly reduced the severity of dermatitis in the mice. This improvement was evident based on clinical assessments of skin condition and was linked to better skin barrier function.
Specifically, those receiving DHA showed reduced water loss from their skin and lessening of certain immune cell responses associated with inflammation. Our results suggest that not only does DHA contribute positively, but combining it with other nutrients amplifies its benefits, potentially offering new dietary management strategies for human eczema.
This study opens up exciting avenues for exploring how certain dietary fats could be used to manage conditions like atopic eczema better. We believe these findings reinforce the importance of nutrition in skin health and inflammation management.
What we found was encouraging. The combination of DHA with arachidonic acid and non-digestible oligosaccharides significantly reduced the severity of dermatitis in the mice. This improvement was evident based on clinical assessments of skin condition and was linked to better skin barrier function.
Specifically, those receiving DHA showed reduced water loss from their skin and lessening of certain immune cell responses associated with inflammation. Our results suggest that not only does DHA contribute positively, but combining it with other nutrients amplifies its benefits, potentially offering new dietary management strategies for human eczema.
This study opens up exciting avenues for exploring how certain dietary fats could be used to manage conditions like atopic eczema better. We believe these findings reinforce the importance of nutrition in skin health and inflammation management.
Read More
We examined how dietary factors, particularly docosahexaenoic acid (DHA), influence the prevalence of atopic eczema among pregnant Japanese females. In a study involving 1,002 participants, we gathered data through a detailed diet history questionnaire, focusing on their intake of various fatty acids and the occurrence of atopic eczema.
Our findings revealed that DHA intake was significantly linked to a reduced rate of atopic eczema both currently and after the age of 18. However, we did not find consistent evidence supporting the idea that n-3 and n-6 polyunsaturated fatty acids, as well as total fat and other types of dietary fat, had a meaningful effect on eczema.
While the study encourages the inclusion of DHA in the diet during pregnancy, it also highlights the complexity of dietary impacts on allergic conditions like eczema. Overall, we observed a noteworthy association between higher DHA intake and lower prevalence rates of eczema in this group, suggesting that it could be a beneficial addition to the diets of pregnant women.
Our findings revealed that DHA intake was significantly linked to a reduced rate of atopic eczema both currently and after the age of 18. However, we did not find consistent evidence supporting the idea that n-3 and n-6 polyunsaturated fatty acids, as well as total fat and other types of dietary fat, had a meaningful effect on eczema.
While the study encourages the inclusion of DHA in the diet during pregnancy, it also highlights the complexity of dietary impacts on allergic conditions like eczema. Overall, we observed a noteworthy association between higher DHA intake and lower prevalence rates of eczema in this group, suggesting that it could be a beneficial addition to the diets of pregnant women.
Read More
8
In a controlled trial, we assessed how docosahexaenoic acid (DHA)—an omega-3 fatty acid—affects atopic eczema. Fifty-three patients, aged 18 to 40, were randomly assigned to receive either 5.4 grams of DHA daily or an isoenergetic control comprising saturated fatty acids for eight weeks. This double-blind setup helped ensure that neither the participants nor the researchers knew who received which treatment, thereby reducing bias in the results.
Throughout the study, we measured the severity of eczema using the SCORAD index at multiple intervals. Our findings showed that DHA supplementation led to a notable improvement in eczema symptoms, with patients experiencing a significant decrease in their SCORAD scores. This contrasted with the control group, which did not show similar improvements. Notably, we also found that DHA reduced certain immune responses linked to eczema, indicating its potential role in managing this condition.
Given these encouraging results, it appears that DHA could be an effective dietary addition for people suffering from atopic eczema. However, further research with a larger participant pool is necessary to confirm these findings and fully understand the benefits of DHA on this skin condition.
Throughout the study, we measured the severity of eczema using the SCORAD index at multiple intervals. Our findings showed that DHA supplementation led to a notable improvement in eczema symptoms, with patients experiencing a significant decrease in their SCORAD scores. This contrasted with the control group, which did not show similar improvements. Notably, we also found that DHA reduced certain immune responses linked to eczema, indicating its potential role in managing this condition.
Given these encouraging results, it appears that DHA could be an effective dietary addition for people suffering from atopic eczema. However, further research with a larger participant pool is necessary to confirm these findings and fully understand the benefits of DHA on this skin condition.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 9 Reviews
7.1
- All Reviews
- Positive Reviews
- Negative Reviews
2
No relief noted
6 people found this helpful
Did not meet my expectations. I purchased this for its anti-inflammatory properties due to my eczema and allergies. Previously, other fish oils relieved my symptoms effectively, even at lower doses of omega-3. However, this product did nothing, despite its higher omega-3 content.
Read More
9
Eczema relief experienced
1 people found this helpful
This product helps with eczema.
Read More
9
Skin condition improved
After taking it for a month, I've seen significant effects. My eczema has improved, my skin feels more moisturised, and it exhibits anti-inflammatory properties.
Read More
9
A must-buy for eczema
The ingredients are of high quality, and each capsule is sizeable without any fishy smell. Given my eczema issues, I take it daily. Its benefits reduce the recurrence of my eczema, making it a product I continually repurchase whenever there’s a sale.
Read More
9
Improves eczema condition
A rich serving of omega-3 significantly improves eczema and alleviates dry skin.
Read More
Frequently Asked Questions
9
Skin condition improved
After taking it for a month, I've seen significant effects. My eczema has improved, my skin feels more moisturised, and it exhibits anti-inflammatory properties.
9
Improves eczema condition
A rich serving of omega-3 significantly improves eczema and alleviates dry skin.
0
No benefit observed
7 people found this helpful
I bought this hoping it would help with my eczema, but I didn’t benefit at all. Even with my deficiencies, it had no impact. I used nearly the whole box and saw no results, potentially because I’m not an athlete. I ended up giving the rest to my brother, who may benefit more.
7.5
Eczema improved significantly
Initially, I tried other fish oils for my eczema, but this one piqued my interest due to its high rating and source from wild Alaskan pollock. Upon taking it, my eczema has improved dramatically. However, I understand that relying solely on this isn’t enough; combining it with hypoallergenic ointments and better habits is essential.
9
A must-buy for eczema
The ingredients are of high quality, and each capsule is sizeable without any fishy smell. Given my eczema issues, I take it daily. Its benefits reduce the recurrence of my eczema, making it a product I continually repurchase whenever there’s a sale.
9
We embarked on a study to find out how dietary eicosapentaenoic acid (EPA) could help children suffering from atopic dermatitis, a common form of eczema. In a randomized triple-blind clinical trial, 48 children with this condition were divided into two groups—one received 250 mg of EPA twice daily, while the other received a placebo for four weeks.
Our observations showed noticeable improvements in those who took EPA. After just two weeks, participants in the EPA group reported a reduction in their SCORAD scores, which are used to measure the severity of atopic dermatitis. The scores went down significantly compared to the placebo group. After four weeks, the number of children needing corticosteroids to manage their symptoms was also lower in the EPA group.
Despite these positive results, both groups reported few adverse effects, indicating that EPA supplementation is generally well-received. Overall, we conclude that adding EPA to the diet may be an effective and safe strategy for reducing eczema severity in children.
Our observations showed noticeable improvements in those who took EPA. After just two weeks, participants in the EPA group reported a reduction in their SCORAD scores, which are used to measure the severity of atopic dermatitis. The scores went down significantly compared to the placebo group. After four weeks, the number of children needing corticosteroids to manage their symptoms was also lower in the EPA group.
Despite these positive results, both groups reported few adverse effects, indicating that EPA supplementation is generally well-received. Overall, we conclude that adding EPA to the diet may be an effective and safe strategy for reducing eczema severity in children.
7
We focused on understanding how eicosapentaenoic acid (EPA), a type of omega-3 fatty acid found in fish, influences the prevalence of eczema among Japanese school-aged children. The study included 135 students with eczema, 136 with asthma, and 137 healthy controls, all from the fifth and eighth grades in Shunan, Japan.
Through questionnaires, we assessed the participants' dietary intake, specifically their fish consumption, and measured total serum IgE levels, a marker linked to allergic responses. The results indicated that those who consumed fatty or dried fish had a lower prevalence of eczema compared to others, highlighting the potential protective effect of fish in our diet.
Interestingly, we saw that only the levels of EPA in the blood had a negative association with eczema, meaning higher EPA levels may reduce the incidence of this condition. Despite these encouraging findings regarding EPA and eczema, we found that fish consumption did not have a significant effect on asthma.
Overall, our findings suggest that including more fish in the diet could be beneficial for reducing eczema in children, with EPA playing a key role in this protective effect.
Through questionnaires, we assessed the participants' dietary intake, specifically their fish consumption, and measured total serum IgE levels, a marker linked to allergic responses. The results indicated that those who consumed fatty or dried fish had a lower prevalence of eczema compared to others, highlighting the potential protective effect of fish in our diet.
Interestingly, we saw that only the levels of EPA in the blood had a negative association with eczema, meaning higher EPA levels may reduce the incidence of this condition. Despite these encouraging findings regarding EPA and eczema, we found that fish consumption did not have a significant effect on asthma.
Overall, our findings suggest that including more fish in the diet could be beneficial for reducing eczema in children, with EPA playing a key role in this protective effect.
7
We examined the potential benefits of eicosapentaenoic acid (EPA) in treating eczema by analyzing squid phospholipids derived from Todarodes pacificus. The research utilized established models, including the rat paw edema model and an atopic dermatitis-like mouse model (NC/Nga mice), allowing us to assess the effectiveness of this treatment.
The squid phospholipids primarily contained essential fatty acids like docosahexaenoic acid (DHA), EPA, and arachidonic acid, which are believed to contribute to their anti-inflammatory properties. In our testing, squid phospholipids notably reduced skin inflammation in the mouse model, leading to improvements in dermatitis symptoms. However, we observed that while these phospholipids showed promising results, the isolated impact of EPA alone could not be definitively established due to the complexities of the treatment's composition.
Our findings indicate that while squid phospholipids, which include EPA, may help in the management of eczema, other components within them also play significant roles in their overall effectiveness. Therefore, further research will be necessary to isolate and clarify how eicosapentaenoic acid specifically influences eczema outcomes.
The squid phospholipids primarily contained essential fatty acids like docosahexaenoic acid (DHA), EPA, and arachidonic acid, which are believed to contribute to their anti-inflammatory properties. In our testing, squid phospholipids notably reduced skin inflammation in the mouse model, leading to improvements in dermatitis symptoms. However, we observed that while these phospholipids showed promising results, the isolated impact of EPA alone could not be definitively established due to the complexities of the treatment's composition.
Our findings indicate that while squid phospholipids, which include EPA, may help in the management of eczema, other components within them also play significant roles in their overall effectiveness. Therefore, further research will be necessary to isolate and clarify how eicosapentaenoic acid specifically influences eczema outcomes.
9
Eicosapentaenoic acid improves eczema
We explored the effects of eicosapentaenoic acid (EPA) ethyl ester on symptoms of atopic dermatitis (AD), a common skin condition characterized by persistent itching and skin barrier dysfunction. In a carefully designed study using hairless mice on a special diet, we observed significant improvements in skin condition after administering EPA.
This study builds on previous findings that showed an increase in serum EPA levels from another omega-3 fatty acid, α-linolenic acid, which similarly helped restore skin health in mice with AD. When we administered EPA to the affected mice, we saw a marked alleviation in both itchy skin and barrier impairment.
A key finding was that the levels of covalently bound ceramides, essential lipids for maintaining our skin's barrier, were greatly reduced in the skin of the AD mice. With EPA treatment, these ceramides were restored, suggesting that EPA may play a crucial role in supporting skin health by improving these lipid levels.
Our findings point to the possible therapeutic application of EPA ethyl ester in treating human eczema, which could lead to effective new options for managing this often-challenging condition.
This study builds on previous findings that showed an increase in serum EPA levels from another omega-3 fatty acid, α-linolenic acid, which similarly helped restore skin health in mice with AD. When we administered EPA to the affected mice, we saw a marked alleviation in both itchy skin and barrier impairment.
A key finding was that the levels of covalently bound ceramides, essential lipids for maintaining our skin's barrier, were greatly reduced in the skin of the AD mice. With EPA treatment, these ceramides were restored, suggesting that EPA may play a crucial role in supporting skin health by improving these lipid levels.
Our findings point to the possible therapeutic application of EPA ethyl ester in treating human eczema, which could lead to effective new options for managing this often-challenging condition.
References
- Sato A, Sato G, Yabuki A, Ogawa Y, Nemoto H, et al. Ameliorative effects of squid phospholipids from Todarodes pacificus on atopic dermatitis-like lesions in NC/Nga mice. Arch Dermatol Res. 2025;317:239. doi:10.1007/s00403-024-03773-9
- Mirrahimi B, Moazemi M, Eslami N, Jamshidi E, Mir M, et al. Evaluating the Effect of Eicosapentaenoic Acid in Children With Atopic Dermatitis: A Randomized Triple-Blind Clinical Trial. J Pediatr Pharmacol Ther. 2023;28:29. doi:10.5863/1551-6776-28.1.29
- Fujii M, Ohyanagi C, Kawaguchi N, Matsuda H, Miyamoto Y, et al. Eicosapentaenoic acid ethyl ester ameliorates atopic dermatitis-like symptoms in special diet-fed hairless mice, partly by restoring covalently bound ceramides in the stratum corneum. Exp Dermatol. 2018;27:837. doi:10.1111/exd.13507
- Kunitsugu I, Okuda M, Murakami N, Hashimoto M, Yamanishi R, et al. Self-reported seafood intake and atopy in Japanese school-aged children. Pediatr Int. 2012;54:233. doi:10.1111/j.1442-200X.2011.03542.x
- Weise C, Ernst D, van Tol EA, Worm M. Dietary polyunsaturated fatty acids and non-digestible oligosaccharides reduce dermatitis in mice. Pediatr Allergy Immunol. 2013;24:361. doi:10.1111/pai.12073
- Montes R, Chisaguano AM, Castellote AI, Morales E, Sunyer J, et al. Fatty-acid composition of maternal and umbilical cord plasma and early childhood atopic eczema in a Spanish cohort. Eur J Clin Nutr. 2013;67:658. doi:10.1038/ejcn.2013.68
- Palmer DJ, Sullivan T, Gold MS, Prescott SL, Heddle R, et al. Effect of n-3 long chain polyunsaturated fatty acid supplementation in pregnancy on infants' allergies in first year of life: randomised controlled trial. BMJ. 2012;344:e184. doi:10.1136/bmj.e184
- Furuhjelm C, Warstedt K, Larsson J, Fredriksson M, Böttcher MF, et al. Fish oil supplementation in pregnancy and lactation may decrease the risk of infant allergy. Acta Paediatr. 2009;98:1461. doi:10.1111/j.1651-2227.2009.01355.x
- Miyake Y, Sasaki S, Tanaka K, Ohya Y, Matsunaga I, et al. Relationship between dietary fat and fish intake and the prevalence of atopic eczema in pregnant Japanese females: baseline data from the Osaka Maternal and Child Health Study. Asia Pac J Clin Nutr. 2008;17:612.
- Koch C, Dölle S, Metzger M, Rasche C, Jungclas H, et al. Docosahexaenoic acid (DHA) supplementation in atopic eczema: a randomized, double-blind, controlled trial. Br J Dermatol. 2008;158:786. doi:10.1111/j.1365-2133.2007.08430.x
