Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 13 Researches
7.3
USERS' SCORE
Moderately Good
Based on 8 Reviews
7.1
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
15
Total Fat
1.5 g
2%**
Wild Caught Fish Oil Concentrate
1250 mg
†
Total Omega-3 Fatty Acids as TG
1055 mg
†
EPA (Eicosapentaenoic Acid)
690 mg
†
DHA (Docosahexaenoic Acid)
310 mg
†
Other Omega-3 Fatty Acids
55 mg
†
Top Medical Research Studies
9.5
We conducted a 12-week study to explore how eicosapentaenoic acid (EPA) affects individuals suffering from episodic migraines. In our trial, 70 participants were randomly split into two groups—one received 2 grams of fish oil with 1.8 grams of pure EPA daily, while the other group got a placebo made of soybean oil.
The results were quite promising. Those taking EPA reported a significant reduction in the number of migraine days per month, averaging about 4.4 fewer days compared to just 0.6 fewer days in the placebo group. We also noticed a decline in the usage of medication to treat headache symptoms among those taking EPA.
Additionally, participants experienced less severe headaches and improved psychological wellbeing, as indicated by better scores in anxiety, depression, and overall quality of life measures. Notably, women seemed to benefit even more from EPA.
Overall, it appears that high-dose EPA can be an effective preventive treatment for episodic migraines, helping to ease frequency, severity, and even the emotional toll associated with chronic headaches. Importantly, the treatment was well tolerated, with no significant adverse effects reported.
The results were quite promising. Those taking EPA reported a significant reduction in the number of migraine days per month, averaging about 4.4 fewer days compared to just 0.6 fewer days in the placebo group. We also noticed a decline in the usage of medication to treat headache symptoms among those taking EPA.
Additionally, participants experienced less severe headaches and improved psychological wellbeing, as indicated by better scores in anxiety, depression, and overall quality of life measures. Notably, women seemed to benefit even more from EPA.
Overall, it appears that high-dose EPA can be an effective preventive treatment for episodic migraines, helping to ease frequency, severity, and even the emotional toll associated with chronic headaches. Importantly, the treatment was well tolerated, with no significant adverse effects reported.
Read More
8
A recent study examined the impact of eicosapentaenoic acid (EPA) on chronic migraine sufferers. We engaged a well-structured research approach through a randomized, blinded, placebo-controlled trial. This allowed us to compare a group receiving 2000 mg of EPA daily to a control group taking placebo softgels for eight weeks.
Our primary focus was on how EPA affects headache frequency and severity. We measured outcomes using a popular tool called the Headache Impact Test-6, along with tracking the number of headache days and the severity of headaches via a visual scale. The results indicated that supplementing with EPA could provide significant benefits in reducing migraine attacks and improving overall quality of life for those with chronic migraines.
This study showcases the potential of EPA as a valuable addition to chronic migraine management, presenting promising evidence for its anti-inflammatory effects. Patients and healthcare providers alike may find hope in the findings, as they suggest that EPA could be an effective prophylactic treatment for managing persistent migraine symptoms.
Our primary focus was on how EPA affects headache frequency and severity. We measured outcomes using a popular tool called the Headache Impact Test-6, along with tracking the number of headache days and the severity of headaches via a visual scale. The results indicated that supplementing with EPA could provide significant benefits in reducing migraine attacks and improving overall quality of life for those with chronic migraines.
This study showcases the potential of EPA as a valuable addition to chronic migraine management, presenting promising evidence for its anti-inflammatory effects. Patients and healthcare providers alike may find hope in the findings, as they suggest that EPA could be an effective prophylactic treatment for managing persistent migraine symptoms.
Read More
8
Eicosapentaenoic acid linked to headache relief
We set out to investigate whether dietary intake of eicosapentaenoic acid (EPA), a type of omega-3 polyunsaturated fatty acid, could influence headache prevalence among U.S. adults. Using data from the National Health and Nutrition Examination Surveys conducted between 1999 and 2004, we analyzed responses from over 12,000 individuals aged 20 and above regarding their experiences with severe headaches or migraines in the past three months.
Our findings showed that higher dietary intake of EPA is linked to a lower occurrence of severe headaches or migraines. Specifically, for every log unit increase in EPA, the odds of experiencing a severe headache decreased significantly. Likewise, a similar relationship was observed with docosahexaenoic acid (DHA), another omega-3 fatty acid, suggesting that both may have a protective effect against headaches.
Interestingly, we noted that this association was particularly strong among non-Mexican Hispanic participants. Even after considering inflammation markers like C-reactive protein, the connection between omega-3 intake and headache prevalence remained robust. Overall, our results support the idea that incorporating more EPA and DHA into our diets could potentially help in reducing headache frequency.
Our findings showed that higher dietary intake of EPA is linked to a lower occurrence of severe headaches or migraines. Specifically, for every log unit increase in EPA, the odds of experiencing a severe headache decreased significantly. Likewise, a similar relationship was observed with docosahexaenoic acid (DHA), another omega-3 fatty acid, suggesting that both may have a protective effect against headaches.
Interestingly, we noted that this association was particularly strong among non-Mexican Hispanic participants. Even after considering inflammation markers like C-reactive protein, the connection between omega-3 intake and headache prevalence remained robust. Overall, our results support the idea that incorporating more EPA and DHA into our diets could potentially help in reducing headache frequency.
Read More
Most Useful Reviews
10
Energy boost
1 people found this helpful
The best omega I've tried. Each capsule has a high concentration and is small, making it easy to swallow without any unpleasant taste. It's great for fitness enthusiasts, as it naturally boosts energy levels. Additionally, it has significantly helped with my headaches.
Read More
9
Headaches eliminated
This is my favourite product on iHerb; it has eliminated my headaches and encourages eyelash growth.
Read More
7.5
Powerful relief
I'm repurchasing this product to relieve headaches. I am hopeful for a strong effect given the high content of intense ingredients and quality. I am satisfied with the size, taste, and packaging.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 13 Researches
7.3
- All Researches
9.5
We conducted a 12-week study to explore how eicosapentaenoic acid (EPA) affects individuals suffering from episodic migraines. In our trial, 70 participants were randomly split into two groups—one received 2 grams of fish oil with 1.8 grams of pure EPA daily, while the other group got a placebo made of soybean oil.
The results were quite promising. Those taking EPA reported a significant reduction in the number of migraine days per month, averaging about 4.4 fewer days compared to just 0.6 fewer days in the placebo group. We also noticed a decline in the usage of medication to treat headache symptoms among those taking EPA.
Additionally, participants experienced less severe headaches and improved psychological wellbeing, as indicated by better scores in anxiety, depression, and overall quality of life measures. Notably, women seemed to benefit even more from EPA.
Overall, it appears that high-dose EPA can be an effective preventive treatment for episodic migraines, helping to ease frequency, severity, and even the emotional toll associated with chronic headaches. Importantly, the treatment was well tolerated, with no significant adverse effects reported.
The results were quite promising. Those taking EPA reported a significant reduction in the number of migraine days per month, averaging about 4.4 fewer days compared to just 0.6 fewer days in the placebo group. We also noticed a decline in the usage of medication to treat headache symptoms among those taking EPA.
Additionally, participants experienced less severe headaches and improved psychological wellbeing, as indicated by better scores in anxiety, depression, and overall quality of life measures. Notably, women seemed to benefit even more from EPA.
Overall, it appears that high-dose EPA can be an effective preventive treatment for episodic migraines, helping to ease frequency, severity, and even the emotional toll associated with chronic headaches. Importantly, the treatment was well tolerated, with no significant adverse effects reported.
Read More
9
We conducted a study to understand how changes in the intake of omega-3 and omega-6 fatty acids, particularly eicosapentaenoic acid (EPA), can influence chronic headaches. By focusing on one group consuming a high level of omega-3 and low omega-6, while another group maintained a low omega-6 diet, we aimed to identify any significant improvements in headache symptoms over a 12-week period.
Our findings revealed notable advantages in the group that increased their omega-3 intake. This group reported greater reductions in headache days and hours, alongside improved overall quality of life. Specifically, the high omega-3 group showed a remarkable drop in their headache impact scores, suggesting that eicosapentaenoic acid may play a beneficial role in managing headache pain.
These results shed light on the potential of dietary adjustments in fatty acid intake as a proactive approach to treating chronic headaches. Eicosapentaenoic acid, thanks to its effects on pain relief pathways, seems to contribute positively to this outcome, affording patients a new avenue to explore in their headache management strategies.
Our findings revealed notable advantages in the group that increased their omega-3 intake. This group reported greater reductions in headache days and hours, alongside improved overall quality of life. Specifically, the high omega-3 group showed a remarkable drop in their headache impact scores, suggesting that eicosapentaenoic acid may play a beneficial role in managing headache pain.
These results shed light on the potential of dietary adjustments in fatty acid intake as a proactive approach to treating chronic headaches. Eicosapentaenoic acid, thanks to its effects on pain relief pathways, seems to contribute positively to this outcome, affording patients a new avenue to explore in their headache management strategies.
Read More
9
We explored how dietary changes, specifically increasing omega-3 fatty acids like docosahexaenoic acid (DHA) while lowering omega-6 fatty acids, can influence headache pain. In a trial involving 55 chronic headache patients, we observed significant benefits from this targeted dietary intervention.
Participants in the study experienced notable increases in beneficial compounds derived from DHA, including 2-docosahexaenoylglycerol and docosahexaenoylethanolamine, alongside a decrease in a compound derived from omega-6 fatty acids. Our findings indicate that these changes in endocannabinoids are linked to reductions in both physical pain and psychological distress related to headaches.
The results suggest that adopting a diet rich in omega-3 fatty acids could be a promising way to manage headaches and related psychological issues effectively. This highlights the potential relevance of diet in addressing chronic pain, opening the door for further exploration into personalized nutrition as a valuable strategy for headache relief.
Participants in the study experienced notable increases in beneficial compounds derived from DHA, including 2-docosahexaenoylglycerol and docosahexaenoylethanolamine, alongside a decrease in a compound derived from omega-6 fatty acids. Our findings indicate that these changes in endocannabinoids are linked to reductions in both physical pain and psychological distress related to headaches.
The results suggest that adopting a diet rich in omega-3 fatty acids could be a promising way to manage headaches and related psychological issues effectively. This highlights the potential relevance of diet in addressing chronic pain, opening the door for further exploration into personalized nutrition as a valuable strategy for headache relief.
Read More
8
A recent study examined the impact of eicosapentaenoic acid (EPA) on chronic migraine sufferers. We engaged a well-structured research approach through a randomized, blinded, placebo-controlled trial. This allowed us to compare a group receiving 2000 mg of EPA daily to a control group taking placebo softgels for eight weeks.
Our primary focus was on how EPA affects headache frequency and severity. We measured outcomes using a popular tool called the Headache Impact Test-6, along with tracking the number of headache days and the severity of headaches via a visual scale. The results indicated that supplementing with EPA could provide significant benefits in reducing migraine attacks and improving overall quality of life for those with chronic migraines.
This study showcases the potential of EPA as a valuable addition to chronic migraine management, presenting promising evidence for its anti-inflammatory effects. Patients and healthcare providers alike may find hope in the findings, as they suggest that EPA could be an effective prophylactic treatment for managing persistent migraine symptoms.
Our primary focus was on how EPA affects headache frequency and severity. We measured outcomes using a popular tool called the Headache Impact Test-6, along with tracking the number of headache days and the severity of headaches via a visual scale. The results indicated that supplementing with EPA could provide significant benefits in reducing migraine attacks and improving overall quality of life for those with chronic migraines.
This study showcases the potential of EPA as a valuable addition to chronic migraine management, presenting promising evidence for its anti-inflammatory effects. Patients and healthcare providers alike may find hope in the findings, as they suggest that EPA could be an effective prophylactic treatment for managing persistent migraine symptoms.
Read More
8
Eicosapentaenoic acid linked to headache relief
We set out to investigate whether dietary intake of eicosapentaenoic acid (EPA), a type of omega-3 polyunsaturated fatty acid, could influence headache prevalence among U.S. adults. Using data from the National Health and Nutrition Examination Surveys conducted between 1999 and 2004, we analyzed responses from over 12,000 individuals aged 20 and above regarding their experiences with severe headaches or migraines in the past three months.
Our findings showed that higher dietary intake of EPA is linked to a lower occurrence of severe headaches or migraines. Specifically, for every log unit increase in EPA, the odds of experiencing a severe headache decreased significantly. Likewise, a similar relationship was observed with docosahexaenoic acid (DHA), another omega-3 fatty acid, suggesting that both may have a protective effect against headaches.
Interestingly, we noted that this association was particularly strong among non-Mexican Hispanic participants. Even after considering inflammation markers like C-reactive protein, the connection between omega-3 intake and headache prevalence remained robust. Overall, our results support the idea that incorporating more EPA and DHA into our diets could potentially help in reducing headache frequency.
Our findings showed that higher dietary intake of EPA is linked to a lower occurrence of severe headaches or migraines. Specifically, for every log unit increase in EPA, the odds of experiencing a severe headache decreased significantly. Likewise, a similar relationship was observed with docosahexaenoic acid (DHA), another omega-3 fatty acid, suggesting that both may have a protective effect against headaches.
Interestingly, we noted that this association was particularly strong among non-Mexican Hispanic participants. Even after considering inflammation markers like C-reactive protein, the connection between omega-3 intake and headache prevalence remained robust. Overall, our results support the idea that incorporating more EPA and DHA into our diets could potentially help in reducing headache frequency.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 8 Reviews
7.1
- All Reviews
- Positive Reviews
- Negative Reviews
10
Energy boost
1 people found this helpful
The best omega I've tried. Each capsule has a high concentration and is small, making it easy to swallow without any unpleasant taste. It's great for fitness enthusiasts, as it naturally boosts energy levels. Additionally, it has significantly helped with my headaches.
Read More
9
Headaches eliminated
This is my favourite product on iHerb; it has eliminated my headaches and encourages eyelash growth.
Read More
7.5
Powerful relief
I'm repurchasing this product to relieve headaches. I am hopeful for a strong effect given the high content of intense ingredients and quality. I am satisfied with the size, taste, and packaging.
Read More
7.5
Fewer headaches
Following a recommendation from a YouTuber, I continue to buy this product. Taking omega 3 has resulted in fewer headaches for me. It lacks a fishy scent and boasts a high content.
Read More
7.5
Good support
I believe it helps with headaches. I find it beneficial as it blocks a lot of light.
Read More
Frequently Asked Questions
7.5
Fewer headaches
Following a recommendation from a YouTuber, I continue to buy this product. Taking omega 3 has resulted in fewer headaches for me. It lacks a fishy scent and boasts a high content.
7.5
Powerful relief
I'm repurchasing this product to relieve headaches. I am hopeful for a strong effect given the high content of intense ingredients and quality. I am satisfied with the size, taste, and packaging.
0
Constant headaches
1 people found this helpful
Since I started this product about five days ago, I've experienced constant headaches. I'm unsure if this is a side effect or if others have experienced the same issue.
2
Daily intake headache
I experience a headache if I take 2 or 3 tablets a day.
9
Headaches eliminated
This is my favourite product on iHerb; it has eliminated my headaches and encourages eyelash growth.
10
Energy boost
1 people found this helpful
The best omega I've tried. Each capsule has a high concentration and is small, making it easy to swallow without any unpleasant taste. It's great for fitness enthusiasts, as it naturally boosts energy levels. Additionally, it has significantly helped with my headaches.
8
A recent study examined the impact of eicosapentaenoic acid (EPA) on chronic migraine sufferers. We engaged a well-structured research approach through a randomized, blinded, placebo-controlled trial. This allowed us to compare a group receiving 2000 mg of EPA daily to a control group taking placebo softgels for eight weeks.
Our primary focus was on how EPA affects headache frequency and severity. We measured outcomes using a popular tool called the Headache Impact Test-6, along with tracking the number of headache days and the severity of headaches via a visual scale. The results indicated that supplementing with EPA could provide significant benefits in reducing migraine attacks and improving overall quality of life for those with chronic migraines.
This study showcases the potential of EPA as a valuable addition to chronic migraine management, presenting promising evidence for its anti-inflammatory effects. Patients and healthcare providers alike may find hope in the findings, as they suggest that EPA could be an effective prophylactic treatment for managing persistent migraine symptoms.
Our primary focus was on how EPA affects headache frequency and severity. We measured outcomes using a popular tool called the Headache Impact Test-6, along with tracking the number of headache days and the severity of headaches via a visual scale. The results indicated that supplementing with EPA could provide significant benefits in reducing migraine attacks and improving overall quality of life for those with chronic migraines.
This study showcases the potential of EPA as a valuable addition to chronic migraine management, presenting promising evidence for its anti-inflammatory effects. Patients and healthcare providers alike may find hope in the findings, as they suggest that EPA could be an effective prophylactic treatment for managing persistent migraine symptoms.
9.5
We conducted a 12-week study to explore how eicosapentaenoic acid (EPA) affects individuals suffering from episodic migraines. In our trial, 70 participants were randomly split into two groups—one received 2 grams of fish oil with 1.8 grams of pure EPA daily, while the other group got a placebo made of soybean oil.
The results were quite promising. Those taking EPA reported a significant reduction in the number of migraine days per month, averaging about 4.4 fewer days compared to just 0.6 fewer days in the placebo group. We also noticed a decline in the usage of medication to treat headache symptoms among those taking EPA.
Additionally, participants experienced less severe headaches and improved psychological wellbeing, as indicated by better scores in anxiety, depression, and overall quality of life measures. Notably, women seemed to benefit even more from EPA.
Overall, it appears that high-dose EPA can be an effective preventive treatment for episodic migraines, helping to ease frequency, severity, and even the emotional toll associated with chronic headaches. Importantly, the treatment was well tolerated, with no significant adverse effects reported.
The results were quite promising. Those taking EPA reported a significant reduction in the number of migraine days per month, averaging about 4.4 fewer days compared to just 0.6 fewer days in the placebo group. We also noticed a decline in the usage of medication to treat headache symptoms among those taking EPA.
Additionally, participants experienced less severe headaches and improved psychological wellbeing, as indicated by better scores in anxiety, depression, and overall quality of life measures. Notably, women seemed to benefit even more from EPA.
Overall, it appears that high-dose EPA can be an effective preventive treatment for episodic migraines, helping to ease frequency, severity, and even the emotional toll associated with chronic headaches. Importantly, the treatment was well tolerated, with no significant adverse effects reported.
8
Eicosapentaenoic acid linked to headache relief
We set out to investigate whether dietary intake of eicosapentaenoic acid (EPA), a type of omega-3 polyunsaturated fatty acid, could influence headache prevalence among U.S. adults. Using data from the National Health and Nutrition Examination Surveys conducted between 1999 and 2004, we analyzed responses from over 12,000 individuals aged 20 and above regarding their experiences with severe headaches or migraines in the past three months.
Our findings showed that higher dietary intake of EPA is linked to a lower occurrence of severe headaches or migraines. Specifically, for every log unit increase in EPA, the odds of experiencing a severe headache decreased significantly. Likewise, a similar relationship was observed with docosahexaenoic acid (DHA), another omega-3 fatty acid, suggesting that both may have a protective effect against headaches.
Interestingly, we noted that this association was particularly strong among non-Mexican Hispanic participants. Even after considering inflammation markers like C-reactive protein, the connection between omega-3 intake and headache prevalence remained robust. Overall, our results support the idea that incorporating more EPA and DHA into our diets could potentially help in reducing headache frequency.
Our findings showed that higher dietary intake of EPA is linked to a lower occurrence of severe headaches or migraines. Specifically, for every log unit increase in EPA, the odds of experiencing a severe headache decreased significantly. Likewise, a similar relationship was observed with docosahexaenoic acid (DHA), another omega-3 fatty acid, suggesting that both may have a protective effect against headaches.
Interestingly, we noted that this association was particularly strong among non-Mexican Hispanic participants. Even after considering inflammation markers like C-reactive protein, the connection between omega-3 intake and headache prevalence remained robust. Overall, our results support the idea that incorporating more EPA and DHA into our diets could potentially help in reducing headache frequency.
9
We conducted a study to understand how changes in the intake of omega-3 and omega-6 fatty acids, particularly eicosapentaenoic acid (EPA), can influence chronic headaches. By focusing on one group consuming a high level of omega-3 and low omega-6, while another group maintained a low omega-6 diet, we aimed to identify any significant improvements in headache symptoms over a 12-week period.
Our findings revealed notable advantages in the group that increased their omega-3 intake. This group reported greater reductions in headache days and hours, alongside improved overall quality of life. Specifically, the high omega-3 group showed a remarkable drop in their headache impact scores, suggesting that eicosapentaenoic acid may play a beneficial role in managing headache pain.
These results shed light on the potential of dietary adjustments in fatty acid intake as a proactive approach to treating chronic headaches. Eicosapentaenoic acid, thanks to its effects on pain relief pathways, seems to contribute positively to this outcome, affording patients a new avenue to explore in their headache management strategies.
Our findings revealed notable advantages in the group that increased their omega-3 intake. This group reported greater reductions in headache days and hours, alongside improved overall quality of life. Specifically, the high omega-3 group showed a remarkable drop in their headache impact scores, suggesting that eicosapentaenoic acid may play a beneficial role in managing headache pain.
These results shed light on the potential of dietary adjustments in fatty acid intake as a proactive approach to treating chronic headaches. Eicosapentaenoic acid, thanks to its effects on pain relief pathways, seems to contribute positively to this outcome, affording patients a new avenue to explore in their headache management strategies.
References
- Mohammadnezhad G, Assarzadegan F, Koosha M, Esmaily H. Eicosapentaenoic acid versus placebo as adjunctive therapy in chronic migraine: A randomized controlled trial. Headache. 2025;65:153. doi:10.1111/head.14808
- Wang HF, Liu WC, Zailani H, Yang CC, Chen TB, et al. A 12-week randomized double-blind clinical trial of eicosapentaenoic acid intervention in episodic migraine. Brain Behav Immun. 2024;118:459. doi:10.1016/j.bbi.2024.03.019
- Sanders AE, Weatherspoon ED, Ehrmann BM, Soma PS, Shaikh SR, et al. Circulating Polyunsaturated Fatty Acids and Pain Intensity in Five Chronic Pain Conditions. J Pain. 2023;24:478. doi:10.1016/j.jpain.2022.10.008
- Faurot KR, Cole WR, MacIntosh BA, Dunlap M, Moore CB, et al. Targeted dietary interventions to reduce pain in persistent post-traumatic headache among service members: Protocol for a randomized, controlled parallel-group trial. Contemp Clin Trials. 2022;119:106851. doi:10.1016/j.cct.2022.106851
- Ramsden CE, Zamora D, Faurot KR, MacIntosh B, Horowitz M, et al. Dietary alteration of n-3 and n-6 fatty acids for headache reduction in adults with migraine: randomized controlled trial. BMJ. 2021;374:n1448. doi:10.1136/bmj.n1448
- Sanders AE, Shaikh SR, Slade GD. Long-chain omega-3 fatty acids and headache in the U.S. population. Prostaglandins Leukot Essent Fatty Acids. 2018;135:47. doi:10.1016/j.plefa.2018.06.008
- Mann JD, Faurot KR, MacIntosh B, Palsson OS, Suchindran CM, et al. A sixteen-week three-armed, randomized, controlled trial investigating clinical and biochemical effects of targeted alterations in dietary linoleic acid and n-3 EPA+DHA in adults with episodic migraine: Study protocol. Prostaglandins Leukot Essent Fatty Acids. 2018;128:41. doi:10.1016/j.plefa.2017.11.002
- Soares AA, Louçana PMC, Nasi EP, Sousa KMH, Sá OMS, et al. A double- blind, randomized, and placebo-controlled clinical trial with omega-3 polyunsaturated fatty acids (OPFA ɷ-3) for the prevention of migraine in chronic migraine patients using amitriptyline. Nutr Neurosci. 2018;21:219. doi:10.1080/1028415X.2016.1266133
- Sadeghi O, Maghsoudi Z, Khorvash F, Ghiasvand R, Askari G. The relationship between different fatty acids intake and frequency of migraine attacks. Iran J Nurs Midwifery Res. 2015;20:334.
- Taha AY, Cheon Y, Faurot KF, Macintosh B, Majchrzak-Hong SF, et al. Dietary omega-6 fatty acid lowering increases bioavailability of omega-3 polyunsaturated fatty acids in human plasma lipid pools. Prostaglandins Leukot Essent Fatty Acids. 2014;90:151. doi:10.1016/j.plefa.2014.02.003
- Ramsden CE, Faurot KR, Zamora D, Suchindran CM, MacIntosh BA, et al. Targeted alteration of dietary n-3 and n-6 fatty acids for the treatment of chronic headaches: a randomized trial. Pain. 2013;154:2441. doi:10.1016/j.pain.2013.07.028
- Domenichiello AF, Jensen JR, Zamora D, Horowitz M, Yuan ZX, et al. Identifying oxidized lipid mediators as prognostic biomarkers of chronic posttraumatic headache. Pain. 2020;161:2775. doi:10.1097/j.pain.0000000000001983
- Ramsden CE, Zamora D, Makriyannis A, Wood JT, Mann JD, et al. Diet-induced changes in n-3- and n-6-derived endocannabinoids and reductions in headache pain and psychological distress. J Pain. 2015;16:707. doi:10.1016/j.jpain.2015.04.007
