Overview

SCIENTIFIC SCORE
Questionable
Based on 12 Researches
6.8
USERS' SCORE
Good
Based on 1 Review
8.5

Top Medical Research Studies

9.5
Family education improves anemia treatment
We investigated how family-centered health education influences adherence to iron-folic acid supplements and improves anemia among pregnant women. Through a quasi-experimental trial, we compared results from intervention and control groups, focusing on women aged 14-16 weeks with anemia.

Our findings showed that this educational approach led to notable increases in participants' knowledge and practices regarding anemia management. Significant drops in moderate and mild anemia rates were observed, along with improvements in hemoglobin and ferritin levels. This suggests that better education can effectively enhance anemia status in expectant mothers.
Read More
8
Preconception nutrition helps reduce anemia
We examined various trials that focused on how preconception nutrition supplements affect maternal anemia, using hemoglobin levels as a key indicator. Our review suggests these supplements can significantly lower anemia rates among expectant mothers.

However, the benefits regarding fetal growth remain unclear. While data shows promise, the overall quality of evidence is low, signaling a need for more robust studies in this area. Future research should aim to evaluate comprehensive nutrition packages containing essential nutrients.
Read More
We synthesized specialized iron oxide nanoparticles enhanced with folic acid to tackle cancer-related anemia and improve tumor imaging. Through innovative strategies, these nanoparticles not only showed superior imaging capabilities but also significantly increased red blood cell counts and hemoglobin levels in mice with anemia, offering a safer alternative to blood transfusions. This dual function suggests that these nanoparticles could play a pivotal role in both diagnosing and treating anemia in cancer patients, helping to address a major concern in cancer care.
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Most Useful Reviews

9
Effective absorption
6 people found this helpful
This stuff works! I suffer from severe anemia, with my ferritin levels so low that my folic acid and B12 also drop. My neurologist stressed the importance of maintaining folic acid, so I started taking this product and my values dramatically improved. I will continue to use it indefinitely, as sublingual absorption is the fastest way to benefit from it.
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 12 Researches
6.8
  • All Researches
9.5
Nutrition education reduces anemia rates
We assessed how nutrition education, combined with iron-folic acid supplementation, impacts hemoglobin levels and adherence to supplementation among pregnant women in Ethiopia. Over three months, pregnant women received community-based education and were given supplements for six weeks.

The results were promising! After the intervention, anemia rates fell significantly from 27.8% to 7.2% among those who received education. Moreover, those participants showed much higher adherence to the supplementation compared to those who did not, suggesting that combining education with iron-folic acid intake can effectively improve health outcomes for pregnant women.
Read More
9.5
Family education improves anemia treatment
We investigated how family-centered health education influences adherence to iron-folic acid supplements and improves anemia among pregnant women. Through a quasi-experimental trial, we compared results from intervention and control groups, focusing on women aged 14-16 weeks with anemia.

Our findings showed that this educational approach led to notable increases in participants' knowledge and practices regarding anemia management. Significant drops in moderate and mild anemia rates were observed, along with improvements in hemoglobin and ferritin levels. This suggests that better education can effectively enhance anemia status in expectant mothers.
Read More
8
Preconception nutrition helps reduce anemia
We examined various trials that focused on how preconception nutrition supplements affect maternal anemia, using hemoglobin levels as a key indicator. Our review suggests these supplements can significantly lower anemia rates among expectant mothers.

However, the benefits regarding fetal growth remain unclear. While data shows promise, the overall quality of evidence is low, signaling a need for more robust studies in this area. Future research should aim to evaluate comprehensive nutrition packages containing essential nutrients.
Read More
8
Folic acid supplementation boosts folate levels
We conducted a school-based study to explore the effects of a weekly iron and folic acid supplementation program on folate levels in adolescent girls in Southern Ethiopia. By comparing 165 girls enrolled in the program with 165 who were not, we found that those receiving supplementation had significantly higher serum folate and hemoglobin levels. The results suggest that this program effectively improves key nutritional markers, highlighting the importance of expanding such initiatives in areas suffering from anemia and folate deficiency.
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We explored a rare case of a 28-year-old man with AIDS who developed severe aplastic anemia after 11 years of taking zidovudine, an antiviral drug. Despite the common belief that anemia from zidovudine occurs early on, this case shows it can happen much later.

After diagnosing the patient, we identified the zidovudine as a contributing factor and switched him to alternative medications. Remarkably, with treatment including blood transfusions and folic acid, his condition improved significantly, and by six weeks post-discharge, his anemia was resolved.
Read More

User Reviews

USERS' SCORE
Good
Based on 1 Review
8.5
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Effective absorption
6 people found this helpful
This stuff works! I suffer from severe anemia, with my ferritin levels so low that my folic acid and B12 also drop. My neurologist stressed the importance of maintaining folic acid, so I started taking this product and my values dramatically improved. I will continue to use it indefinitely, as sublingual absorption is the fastest way to benefit from it.
Read More

Frequently Asked Questions

No FAQs are available for this product and symptom.

References

  1. Upadhyay RP, Chowdhury R, Mundra S, Taneja S, Jacob M, et al. Comparative effectiveness of daily therapeutic supplementation with multiple micronutrients and iron-folic acid versus iron-folic acid alone in children with mild-to-moderate anaemia in rural India: an open-label, randomised controlled trial. Lancet Glob Health. 2025;13:e497. doi:10.1016/S2214-109X(24)00559-X
  2. Engidaw MT, Lee P, Ahmed F. Iron and folic acid supplementation compliance during pregnancy and its effect on post-pregnancy anaemia among reproductive-age women in East Africa. Womens Health (Lond). 2025;21:17455057251317547. doi:10.1177/17455057251317547
  3. Williams BA, McCartney H, Singer J, Devlin AM, Vercauteren S, et al. Folic acid supplementation in children with sickle cell disease: a randomized double-blind noninferiority cross-over trial. Am J Clin Nutr. 2025;121:910. doi:10.1016/j.ajcnut.2025.02.001
  4. Anato A, Reshid M. Effect of nutrition education and iron-folic acid supplementation on anemia among pregnant women in Ethiopia: a quasi-experimental study. Sci Rep. 2025;15:3556. doi:10.1038/s41598-025-87957-x
  5. Aziz Ali S, Genkinger J, Kahe K, Valeri L, Khowaja N, et al. Role of preconception nutrition supplements in maternal anemia and intrauterine growth: a systematic review and meta-analysis of randomized controlled trials. Syst Rev. 2025;14:11. doi:10.1186/s13643-024-02726-7
  6. Bolka A, Bosha T, Gebremedhin S. Effect of School-Based Weekly Iron and Folic Acid Supplementation Program on the Serum Folate Status of Adolescent Girls in Sidama Region, Southern Ethiopia: Comparative Cross-Sectional Study. Food Nutr Bull. 2025. doi:10.1177/03795721241304475
  7. Chillo SL, Woldesemayat EM, Dangisso MH. Intermittent versus daily oral iron folic acid supplementation and pregnancy outcome in low- and middle-income countries: a systematic review and meta-analysis of experimental studies. Reprod Health. 2025;22:2. doi:10.1186/s12978-024-01917-8
  8. Zhou J, Wang Q, Yu Y, Chen L, Shi J, et al. A rare case report of severe aplastic anaemia caused by long-term use of zidovudine. BMC Infect Dis. 2024;24:1421. doi:10.1186/s12879-024-09875-z
  9. Singh G, Ranjitha R, Baskaran P, Goel AD, Gupta MK, et al. Family-centered Health Education Intervention for Improving Iron-folic Acid Adherence and Anemia Reduction among Antenatal Mothers in Rural Jodhpur: A Quasi-experimental Study. Indian J Public Health. 2024;68:495. doi:10.4103/ijph.ijph_844_23
  10. Zhang C, Cha R, Long K, Liu Y, Dong Y, et al. Functionalized Iron Oxide Nanoparticles for Both Dual-Modal Imaging and Erythropoiesis. ACS Appl Mater Interfaces. 2024;16:68905. doi:10.1021/acsami.4c15206
  11. Behera DK, Rahut DB, Tripathy S, Negi S. Burden and causes of anemia in Vietnam: insights from the global burden of disease data. BMC Public Health. 2024;24:3026. doi:10.1186/s12889-024-20497-7
  12. Finkelstein JL, Cuthbert A, Weeks J, Venkatramanan S, Larvie DY, et al. Daily oral iron supplementation during pregnancy. Cochrane Database Syst Rev. 2024;8:CD004736. doi:10.1002/14651858.CD004736.pub6
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