Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7.6
USERS' SCORE
Good
Based on 5 Reviews
8.6
Supplement Facts
Serving Size: 1 MicroLingual® Tablet
Amount Per Serving
%DV
Vitamin D (as cholecalciferol)
125 mcg (5,000 IU)
625%

Top Medical Research Studies

9
Vitamin D lowers cholesterol levels
We investigated how vitamin D3 supplementation impacts cholesterol levels in pediatric patients with obesity. During our study, we divided 723 children into two groups: one received vitamin D3 supplements, while the other received a placebo. This allowed us to comprehensively assess the relationship between vitamin D and metabolic health, especially focusing on high cholesterol.

What we found was promising. After introducing vitamin D3 to the participants, we observed a significant drop in various lipid levels among those who received the supplements compared to those who were on the placebo. Specifically, there were notable reductions in total cholesterol, triglycerides, and low-density lipoprotein (LDL), alongside improvements in high-density lipoprotein (HDL).

Our results highlight that vitamin D3 not only boosted vitamin D levels but also positively influenced cholesterol metabolism. This suggests that supplementing with vitamin D could be a helpful strategy for managing high cholesterol, particularly in children struggling with obesity. Overall, our findings underscore the potential of vitamin D in improving metabolic health in younger populations.
Read More
8
Vitamin D improves triglycerides and HDL-C
We wanted to understand how vitamin D supplementation affects cholesterol levels, especially in women who are overweight or obese. Our analysis involved reviewing multiple randomized controlled trials, allowing us to look closely at the changes potential vitamin D can bring to lipid profiles.

We found that taking vitamin D led to significant reductions in triglyceride levels and total cholesterol. Specifically, triglycerides dropped by about 6.13 mg/dL, while total cholesterol saw a decrease of 4.45 mg/dL. Interestingly, we also noticed that vitamin D supplementation was linked to an increase in levels of high-density lipoprotein cholesterol (HDL-C), which is often referred to as the "good" cholesterol.

However, it's worth noting that despite these positive changes, vitamin D did not significantly impact low-density lipoprotein cholesterol (LDL-C), often known as the "bad" cholesterol. Therefore, while vitamin D can help with some lipid profile issues, its effect on LDL-C isn’t as pronounced.

Overall, we are encouraged by the results indicating that vitamin D can play a beneficial role in managing triglycerides and cholesterol levels among overweight or obese women, but we acknowledge that more research is needed to fully understand its effects on LDL-C.
Read More
8
Vitamin D associated with cholesterol improvement
Our investigation centered around the link between vitamin D levels and cholesterol, particularly focusing on high cholesterol. We analyzed data from nearly 48,000 outpatients to see how two forms of vitamin D—25-hydroxyvitamin D and 1,25-dihydroxyvitamin D—relate to various cholesterol parameters, such as LDL (the "bad" cholesterol), HDL (the "good" cholesterol), and total cholesterol levels.

We discovered that higher levels of 25(OH)D are connected with lower LDL and total cholesterol levels across the board. This relationship was especially strong among men over 50. Interestingly, the pattern varied for women; they showed a positive correlation with LDL and total cholesterol before age 50, but a negative association afterwards.

HDL levels consistently improved with higher 25(OH)D levels in all age groups, demonstrating the strongest link in postmenopausal women. However, the other form, 1,25(OH)D, only positively associated with HDL in people over 50 and didn't show significant effects on LDL or total cholesterol in any age category.

Overall, we pointed out that elevated levels of 25(OH)D can contribute to better cholesterol profiles, marked by lower levels of LDL and total cholesterol as well as higher HDL levels. This effect was particularly notable in those over 50 and postmenopausal women, highlighting the potential role of vitamin D in managing cholesterol levels.
Read More

Most Useful Reviews

9
Effective vitamin D
2 people found this helpful
I recommend taking vitamin D with this product; it elevates levels quickly. It's consumable, although the quantity can be overwhelming. Highly recommend, ten stars.
Read More
9
Family benefit
1 people found this helpful
After two years of searching for a vitamin D that would raise my family's levels, I found this one. It addressed severe deficiencies; my daughter's level rose from 30 to 69 ng/ml, my husband’s from 16 to 52 ng/ml, and mine from 25 to 70 ng/ml. Highly recommend for all the family.
Read More
9
Health improvement
1 people found this helpful
Given that 80% of the population is deficient in vitamin D, I started taking 10,000 IU daily after a low level was revealed. My level reached 80 ng/ml within six months, and this product is absorbed efficiently without gastrointestinal irritation.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7.6
  • All Researches
9
Vitamin D lowers cholesterol levels
We investigated how vitamin D3 supplementation impacts cholesterol levels in pediatric patients with obesity. During our study, we divided 723 children into two groups: one received vitamin D3 supplements, while the other received a placebo. This allowed us to comprehensively assess the relationship between vitamin D and metabolic health, especially focusing on high cholesterol.

What we found was promising. After introducing vitamin D3 to the participants, we observed a significant drop in various lipid levels among those who received the supplements compared to those who were on the placebo. Specifically, there were notable reductions in total cholesterol, triglycerides, and low-density lipoprotein (LDL), alongside improvements in high-density lipoprotein (HDL).

Our results highlight that vitamin D3 not only boosted vitamin D levels but also positively influenced cholesterol metabolism. This suggests that supplementing with vitamin D could be a helpful strategy for managing high cholesterol, particularly in children struggling with obesity. Overall, our findings underscore the potential of vitamin D in improving metabolic health in younger populations.
Read More
We investigated the relationship between serum levels of vitamin D and the risk of high cholesterol, or hyperlipidemia, among adults in a prospective cohort study. This research involved collecting data over three years to understand how vitamin D might influence cholesterol levels, particularly focusing on different ranges of vitamin D sufficiency.

Our findings indicated that individuals with low vitamin D levels faced a significantly higher risk of developing hyperlipidemia. Specifically, those deficient in vitamin D had over 1.5 times the risk compared to those with adequate levels of this essential vitamin.

Additionally, a notable percentage of participants were found to have vitamin D deficiency, particularly among middle-aged and older adults. This suggests a potential link between lifestyle factors accompanying low vitamin D levels and the increased likelihood of high cholesterol.

Overall, these insights point to the promising possibility of improving cholesterol profiles through adequate vitamin D intake, but further research is likely needed to develop clear treatment pathways based solely on vitamin D supplementation.
Read More
8
Vitamin D improves triglycerides and HDL-C
We wanted to understand how vitamin D supplementation affects cholesterol levels, especially in women who are overweight or obese. Our analysis involved reviewing multiple randomized controlled trials, allowing us to look closely at the changes potential vitamin D can bring to lipid profiles.

We found that taking vitamin D led to significant reductions in triglyceride levels and total cholesterol. Specifically, triglycerides dropped by about 6.13 mg/dL, while total cholesterol saw a decrease of 4.45 mg/dL. Interestingly, we also noticed that vitamin D supplementation was linked to an increase in levels of high-density lipoprotein cholesterol (HDL-C), which is often referred to as the "good" cholesterol.

However, it's worth noting that despite these positive changes, vitamin D did not significantly impact low-density lipoprotein cholesterol (LDL-C), often known as the "bad" cholesterol. Therefore, while vitamin D can help with some lipid profile issues, its effect on LDL-C isn’t as pronounced.

Overall, we are encouraged by the results indicating that vitamin D can play a beneficial role in managing triglycerides and cholesterol levels among overweight or obese women, but we acknowledge that more research is needed to fully understand its effects on LDL-C.
Read More
8
Ergosterol may improve cholesterol levels
We explored how ergosterol, a precursor of vitamin D, impacts cholesterol levels and vitamin D biosynthesis in ovariectomized (OVX) rats. Our study revealed that daily high ergosterol intake over 14 weeks significantly lowered plasma cholesterol levels, an important finding since high cholesterol can lead to various health issues.

Additionally, we found that treated OVX rats had higher levels of 7-dehydrocholesterol, a precursor to vitamin D, suggesting that ergosterol not only helps decrease cholesterol but may also promote improved vitamin D synthesis. We also observed a slight increase in the active form of vitamin D in these rats.

Perhaps most excitingly, ergosterol contributed to better bone strength, countering some of the effects of OVX-induced bone resorption. This suggests that ergosterol could be a promising option for addressing both dyslipidemia and osteoporosis in postmenopausal women, providing a dual benefit for health.

Overall, our findings support the idea that ergosterol could be an adjunct to traditional treatments for managing cholesterol and promoting vitamin D levels.
Read More
8
Vitamin D associated with cholesterol improvement
Our investigation centered around the link between vitamin D levels and cholesterol, particularly focusing on high cholesterol. We analyzed data from nearly 48,000 outpatients to see how two forms of vitamin D—25-hydroxyvitamin D and 1,25-dihydroxyvitamin D—relate to various cholesterol parameters, such as LDL (the "bad" cholesterol), HDL (the "good" cholesterol), and total cholesterol levels.

We discovered that higher levels of 25(OH)D are connected with lower LDL and total cholesterol levels across the board. This relationship was especially strong among men over 50. Interestingly, the pattern varied for women; they showed a positive correlation with LDL and total cholesterol before age 50, but a negative association afterwards.

HDL levels consistently improved with higher 25(OH)D levels in all age groups, demonstrating the strongest link in postmenopausal women. However, the other form, 1,25(OH)D, only positively associated with HDL in people over 50 and didn't show significant effects on LDL or total cholesterol in any age category.

Overall, we pointed out that elevated levels of 25(OH)D can contribute to better cholesterol profiles, marked by lower levels of LDL and total cholesterol as well as higher HDL levels. This effect was particularly notable in those over 50 and postmenopausal women, highlighting the potential role of vitamin D in managing cholesterol levels.
Read More

User Reviews

USERS' SCORE
Good
Based on 5 Reviews
8.6
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Effective vitamin D
2 people found this helpful
I recommend taking vitamin D with this product; it elevates levels quickly. It's consumable, although the quantity can be overwhelming. Highly recommend, ten stars.
Read More
9
Family benefit
1 people found this helpful
After two years of searching for a vitamin D that would raise my family's levels, I found this one. It addressed severe deficiencies; my daughter's level rose from 30 to 69 ng/ml, my husband’s from 16 to 52 ng/ml, and mine from 25 to 70 ng/ml. Highly recommend for all the family.
Read More
9
Health improvement
1 people found this helpful
Given that 80% of the population is deficient in vitamin D, I started taking 10,000 IU daily after a low level was revealed. My level reached 80 ng/ml within six months, and this product is absorbed efficiently without gastrointestinal irritation.
Read More
9
Effective results
This is the best vitamin D I've used. It dissolves under the tongue, ensuring quick absorption. After one week on 10,000 IU, my levels improved significantly to 70 ng/ml. I advise regular testing for dose adjustment.
Read More
7.5
Quick absorption
1 people found this helpful
Ideal for those struggling to absorb regular vitamin D due to digestive issues. This product bypasses the gastrointestinal tract, dissolving quickly under the tongue for immediate absorption. It's convenient for travel too.
Read More

Frequently Asked Questions

9
Family benefit
1 people found this helpful
After two years of searching for a vitamin D that would raise my family's levels, I found this one. It addressed severe deficiencies; my daughter's level rose from 30 to 69 ng/ml, my husband’s from 16 to 52 ng/ml, and mine from 25 to 70 ng/ml. Highly recommend for all the family.
9
Effective results
This is the best vitamin D I've used. It dissolves under the tongue, ensuring quick absorption. After one week on 10,000 IU, my levels improved significantly to 70 ng/ml. I advise regular testing for dose adjustment.
9
Health improvement
1 people found this helpful
Given that 80% of the population is deficient in vitamin D, I started taking 10,000 IU daily after a low level was revealed. My level reached 80 ng/ml within six months, and this product is absorbed efficiently without gastrointestinal irritation.
8
Vitamin D improves triglycerides and HDL-C
We wanted to understand how vitamin D supplementation affects cholesterol levels, especially in women who are overweight or obese. Our analysis involved reviewing multiple randomized controlled trials, allowing us to look closely at the changes potential vitamin D can bring to lipid profiles.

We found that taking vitamin D led to significant reductions in triglyceride levels and total cholesterol. Specifically, triglycerides dropped by about 6.13 mg/dL, while total cholesterol saw a decrease of 4.45 mg/dL. Interestingly, we also noticed that vitamin D supplementation was linked to an increase in levels of high-density lipoprotein cholesterol (HDL-C), which is often referred to as the "good" cholesterol.

However, it's worth noting that despite these positive changes, vitamin D did not significantly impact low-density lipoprotein cholesterol (LDL-C), often known as the "bad" cholesterol. Therefore, while vitamin D can help with some lipid profile issues, its effect on LDL-C isn’t as pronounced.

Overall, we are encouraged by the results indicating that vitamin D can play a beneficial role in managing triglycerides and cholesterol levels among overweight or obese women, but we acknowledge that more research is needed to fully understand its effects on LDL-C.
9
Vitamin D lowers cholesterol levels
We investigated how vitamin D3 supplementation impacts cholesterol levels in pediatric patients with obesity. During our study, we divided 723 children into two groups: one received vitamin D3 supplements, while the other received a placebo. This allowed us to comprehensively assess the relationship between vitamin D and metabolic health, especially focusing on high cholesterol.

What we found was promising. After introducing vitamin D3 to the participants, we observed a significant drop in various lipid levels among those who received the supplements compared to those who were on the placebo. Specifically, there were notable reductions in total cholesterol, triglycerides, and low-density lipoprotein (LDL), alongside improvements in high-density lipoprotein (HDL).

Our results highlight that vitamin D3 not only boosted vitamin D levels but also positively influenced cholesterol metabolism. This suggests that supplementing with vitamin D could be a helpful strategy for managing high cholesterol, particularly in children struggling with obesity. Overall, our findings underscore the potential of vitamin D in improving metabolic health in younger populations.
7
Vitamin D's link to cholesterol
We investigated the relationship between vitamin D levels and the atherogenic index of plasma (AIP), which is closely tied to cholesterol levels. Our analysis included data from 9,637 adults collected in the National Health and Nutrition Examination Survey between 2011 and 2018.

We found that higher serum vitamin D levels are linked to lower AIP values, indicating a potential benefit in managing cholesterol. This negative correlation was particularly significant among male participants, Non-Hispanic Black individuals, and those aged 40-70.

Interestingly, we observed a saturation effect, meaning that after reaching a certain level of vitamin D, additional increases didn't result in further decreases in AIP. This turning point was identified at about 8.56 nmol/L of serum vitamin D.

Overall, while our findings suggest a beneficial relationship between vitamin D and cholesterol levels, it's essential to approach this with caution since the study did not explicitly test vitamin D as a treatment for high cholesterol. Further research would be needed to establish any direct treatment implications.
We investigated the relationship between serum levels of vitamin D and the risk of high cholesterol, or hyperlipidemia, among adults in a prospective cohort study. This research involved collecting data over three years to understand how vitamin D might influence cholesterol levels, particularly focusing on different ranges of vitamin D sufficiency.

Our findings indicated that individuals with low vitamin D levels faced a significantly higher risk of developing hyperlipidemia. Specifically, those deficient in vitamin D had over 1.5 times the risk compared to those with adequate levels of this essential vitamin.

Additionally, a notable percentage of participants were found to have vitamin D deficiency, particularly among middle-aged and older adults. This suggests a potential link between lifestyle factors accompanying low vitamin D levels and the increased likelihood of high cholesterol.

Overall, these insights point to the promising possibility of improving cholesterol profiles through adequate vitamin D intake, but further research is likely needed to develop clear treatment pathways based solely on vitamin D supplementation.

References

  1. Liu ZY, Liu S, Yao X, Wang CY, Song Y, et al. A cohort study of serum 25-hydroxyvitamin D levels and the risk of hyperlipidaemia in adults. Front Nutr. 2024;11:1492621. 10.3389/fnut.2024.1492621
  2. Hu L, Velu P, Prabahar K, Hernández-Wolters B, Kord-Varkaneh H, et al. Effect of Vitamin D Supplementation on Lipid Profile in Overweight or Obese Women: A Meta-analysis and Systematic Review of Randomized Controlled Trials. Nutr Rev. 2025. 10.1093/nutrit/nuae226
  3. Kuwabara N, Kanda J, Sato S, Nakagawa S. Impact of Daily High Ergosterol Intake for 14 Weeks in Ovariectomized Rats on Cholesterol and Vitamin D Biosynthesis Pathways. Biol Pharm Bull. 2025;48:39. 10.1248/bpb.b24-00536
  4. Wang F, Bei L, Zhang X, Fu Y. Vitamin D Supplementation Reduces Hyperlipidemia and Improves Bone Mass in Pediatric Obesity. Crit Rev Immunol. 2025;45:31. 10.1615/CritRevImmunol.2024052129
  5. Li X, Liu Y, Wang J, Chen X, Reichetzeder C, et al. Vitamin D Is Associated with Lipid Metabolism: A Sex- and Age-Dependent Analysis of a Large Outpatient Cohort. Nutrients. 2024;16. 10.3390/nu16223936
  6. Hu T, Zhang Y, Chen Z, Su J. Relationship between serum vitamin D levels and the atherogenic index of plasma: a study based on NHANES database 2011-2018. Front Nutr. 2024;11:1468284. 10.3389/fnut.2024.1468284
  7. Xu H, Qiu S, Lin P, Liao X, Lin Y, et al. Vitamin D has therapeutic effects on obesity and hyperandrogenemia in PCOS mouse model induced by low dose DHEA and high-fat diet. BMC Womens Health. 2024;24:601. 10.1186/s12905-024-03445-w
  8. Sadeghi M, Momeni A, Mirsaeidi FS, Jamalian M, Amirpour A, et al. The Effect of Vitamin D Deficiency Treatment on Lipid Profile and C-reactive Protein in Patients with Ischemic Heart Disease: Double-blind Randomized Clinical Trial. Adv Biomed Res. 2024;13:79. 10.4103/abr.abr_380_23
  9. Wang J, Shi T, Xu L, Li Y, Mi W, et al. Correlation between hyperlipidemia and serum vitamin D levels in an adult Chinese cohort. Front Nutr. 2024;11:1302260. 10.3389/fnut.2024.1302260
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