Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Moderately Good
Based on 4 Reviews
7
Supplement Facts
Serving Size: 3 Softgels
Amount Per Serving
%DV
Garlic Oil Concentrate (Allium sativum) (Bulb) (Equivalent to 4,500 mg of Whole Clove Garlic)
9 mg
*

Top Medical Research Studies

9
Garlic extract alleviates diarrhea
We explored the potential of garlic-derived exosome-like nanoparticles, known as garlic exosome-like nanoparticles (GELNs), in addressing diarrhea related to ulcerative colitis (UC). In our study, we found that GELNs, which are small particles that carry beneficial proteins and microRNAs, can effectively protect against the symptoms of UC.

Our research involved administering GELNs to mice suffering from DSS-induced colitis. The results were promising; the garlic nanoparticles significantly reduced bloody diarrhea and helped normalize the production of inflammatory substances in the body. Additionally, they played a key role in maintaining the integrity of the colonic barrier, which is crucial for gut health.

We discovered that GELNs were taken up by gut microbes, leading to a healthier balance of gut bacteria, especially boosting a beneficial type of bacteria called Bacteroides thetaiotaomicron. This bacterium is known to have positive effects on gut health and can alleviate colitis symptoms.

Overall, our findings suggest that garlic exosomes hold great promise as a natural treatment for managing UC and its associated diarrhea, showcasing their potential as innovative therapeutic agents.
Read More
7
Garlic's unclear effect on diarrhea
We explored the potential effects of garlic on diarrhea caused by intestinal protozoan pathogens. While some studies have indicated that garlic can impact cysteine proteases (CPs) secreted by these pathogens, there is limited information on its direct effectiveness in treating diarrhea.

The exposure of host epithelial cells to these CPs has been linked to increased intestinal damage. Despite the promising aspects related to garlic's ability to affect these enzymes, specific data showing significant improvements in diarrhea treatment outcomes remain sparse.

It's clear that while garlic has certain beneficial properties, its role in mitigating diarrhea associated with these infections needs more investigation. Presently, we should be cautious about overestimating garlic's effectiveness as a standalone treatment option.
Read More

Most Useful Reviews

0
Stopped due to diarrhea
4 people found this helpful
I did not feel well at all. I began taking garlic oil, but regrettably had to cease. Firstly, there is an odour that becomes evident when conversing with those nearby. Secondly, I experienced troubling diarrhea. Overall, I found it necessary to stop.
Read More
7.5
Improvement for discomfort
Very good and affordable, garlic oil can be beneficial for those with intestinal discomfort. I experienced diarrhoea previously, but after using it, I felt an improvement.
Read More
6
Positive effect on diarrhea
Excellent quality. The capsules are small and have a garlicky flavour, which may linger even when taken with food. They appear to help combat diarrhoea and have personally had a beneficial impact on my blood, resulting in fewer headaches due to their thinning effect.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
  • All Researches
9
Garlic extract alleviates diarrhea
We explored the potential of garlic-derived exosome-like nanoparticles, known as garlic exosome-like nanoparticles (GELNs), in addressing diarrhea related to ulcerative colitis (UC). In our study, we found that GELNs, which are small particles that carry beneficial proteins and microRNAs, can effectively protect against the symptoms of UC.

Our research involved administering GELNs to mice suffering from DSS-induced colitis. The results were promising; the garlic nanoparticles significantly reduced bloody diarrhea and helped normalize the production of inflammatory substances in the body. Additionally, they played a key role in maintaining the integrity of the colonic barrier, which is crucial for gut health.

We discovered that GELNs were taken up by gut microbes, leading to a healthier balance of gut bacteria, especially boosting a beneficial type of bacteria called Bacteroides thetaiotaomicron. This bacterium is known to have positive effects on gut health and can alleviate colitis symptoms.

Overall, our findings suggest that garlic exosomes hold great promise as a natural treatment for managing UC and its associated diarrhea, showcasing their potential as innovative therapeutic agents.
Read More
7
Garlic's unclear effect on diarrhea
We explored the potential effects of garlic on diarrhea caused by intestinal protozoan pathogens. While some studies have indicated that garlic can impact cysteine proteases (CPs) secreted by these pathogens, there is limited information on its direct effectiveness in treating diarrhea.

The exposure of host epithelial cells to these CPs has been linked to increased intestinal damage. Despite the promising aspects related to garlic's ability to affect these enzymes, specific data showing significant improvements in diarrhea treatment outcomes remain sparse.

It's clear that while garlic has certain beneficial properties, its role in mitigating diarrhea associated with these infections needs more investigation. Presently, we should be cautious about overestimating garlic's effectiveness as a standalone treatment option.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 4 Reviews
7
  • All Reviews
  • Positive Reviews
  • Negative Reviews
0
Stopped due to diarrhea
4 people found this helpful
I did not feel well at all. I began taking garlic oil, but regrettably had to cease. Firstly, there is an odour that becomes evident when conversing with those nearby. Secondly, I experienced troubling diarrhea. Overall, I found it necessary to stop.
Read More
7.5
Improvement for discomfort
Very good and affordable, garlic oil can be beneficial for those with intestinal discomfort. I experienced diarrhoea previously, but after using it, I felt an improvement.
Read More
6
Positive effect on diarrhea
Excellent quality. The capsules are small and have a garlicky flavour, which may linger even when taken with food. They appear to help combat diarrhoea and have personally had a beneficial impact on my blood, resulting in fewer headaches due to their thinning effect.
Read More
2
Burning sensation noted
1 people found this helpful
It's beautiful, yet I have a sensitive colon, which resulted in a burning feeling. I later tried it before bed with a light meal, but unfortunately, I encountered a diarrhoea issue afterwards. Thank goodness for that.
Read More

Frequently Asked Questions

7.5
Improvement for discomfort
Very good and affordable, garlic oil can be beneficial for those with intestinal discomfort. I experienced diarrhoea previously, but after using it, I felt an improvement.
6
Positive effect on diarrhea
Excellent quality. The capsules are small and have a garlicky flavour, which may linger even when taken with food. They appear to help combat diarrhoea and have personally had a beneficial impact on my blood, resulting in fewer headaches due to their thinning effect.
0
Stopped due to diarrhea
4 people found this helpful
I did not feel well at all. I began taking garlic oil, but regrettably had to cease. Firstly, there is an odour that becomes evident when conversing with those nearby. Secondly, I experienced troubling diarrhea. Overall, I found it necessary to stop.
2
Burning sensation noted
1 people found this helpful
It's beautiful, yet I have a sensitive colon, which resulted in a burning feeling. I later tried it before bed with a light meal, but unfortunately, I encountered a diarrhoea issue afterwards. Thank goodness for that.
9
Garlic extract alleviates diarrhea
We explored the potential of garlic-derived exosome-like nanoparticles, known as garlic exosome-like nanoparticles (GELNs), in addressing diarrhea related to ulcerative colitis (UC). In our study, we found that GELNs, which are small particles that carry beneficial proteins and microRNAs, can effectively protect against the symptoms of UC.

Our research involved administering GELNs to mice suffering from DSS-induced colitis. The results were promising; the garlic nanoparticles significantly reduced bloody diarrhea and helped normalize the production of inflammatory substances in the body. Additionally, they played a key role in maintaining the integrity of the colonic barrier, which is crucial for gut health.

We discovered that GELNs were taken up by gut microbes, leading to a healthier balance of gut bacteria, especially boosting a beneficial type of bacteria called Bacteroides thetaiotaomicron. This bacterium is known to have positive effects on gut health and can alleviate colitis symptoms.

Overall, our findings suggest that garlic exosomes hold great promise as a natural treatment for managing UC and its associated diarrhea, showcasing their potential as innovative therapeutic agents.
7
Garlic's unclear effect on diarrhea
We explored the potential effects of garlic on diarrhea caused by intestinal protozoan pathogens. While some studies have indicated that garlic can impact cysteine proteases (CPs) secreted by these pathogens, there is limited information on its direct effectiveness in treating diarrhea.

The exposure of host epithelial cells to these CPs has been linked to increased intestinal damage. Despite the promising aspects related to garlic's ability to affect these enzymes, specific data showing significant improvements in diarrhea treatment outcomes remain sparse.

It's clear that while garlic has certain beneficial properties, its role in mitigating diarrhea associated with these infections needs more investigation. Presently, we should be cautious about overestimating garlic's effectiveness as a standalone treatment option.

References

  1. Wang X, Liu Y, Dong X, Duan T, Wang C, et al. peu-MIR2916-p3-enriched garlic exosomes ameliorate murine colitis by reshaping gut microbiota, especially by boosting the anti-colitic Bacteroides thetaiotaomicron. Pharmacol Res. 2024;200:107071. doi:10.1016/j.phrs.2024.107071
  2. Argüello-García R, Carrero JC, Ortega-Pierres MG. Extracellular Cysteine Proteases of Key Intestinal Protozoan Pathogens-Factors Linked to Virulence and Pathogenicity. Int J Mol Sci. 2023;24. doi:10.3390/ijms241612850
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