5/24/2025
Last update
5/24/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Good
Based on 1 Review
8.5
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Zinc(from 270 mg Zinc Picolinate)
50 mg
455%
Top Medical Research Studies
9
We explored the effects of high-dose zinc treatment on angina pectoris, particularly in patients suffering from severe atherosclerotic disease. This study reviewed existing literature and focused on how zinc might help reduce symptoms associated with this condition.
Zinc plays a crucial role in fighting oxidative stress, which is known to be a key player in arteriosclerosis and subsequent angina. Our observations indicated that when patients were given high doses of zinc sulfate, increasing their serum zinc levels significantly, many experienced notable improvements in their angina symptoms.
In fact, 12 out of 16 patients reported better outcomes after treatment. Moreover, it was found that long-term exposure to zinc in the environment appeared to lower incidences of exertional angina, reinforcing the idea that zinc could be beneficial.
We hypothesize that zinc may help prevent the oxidation of harmful LDL cholesterol, therefore slowing down the atherosclerosis process crucial to angina development. Additionally, zinc's effects may relate to its ability to inhibit inflammatory markers, which are often elevated in older adults.
Zinc plays a crucial role in fighting oxidative stress, which is known to be a key player in arteriosclerosis and subsequent angina. Our observations indicated that when patients were given high doses of zinc sulfate, increasing their serum zinc levels significantly, many experienced notable improvements in their angina symptoms.
In fact, 12 out of 16 patients reported better outcomes after treatment. Moreover, it was found that long-term exposure to zinc in the environment appeared to lower incidences of exertional angina, reinforcing the idea that zinc could be beneficial.
We hypothesize that zinc may help prevent the oxidation of harmful LDL cholesterol, therefore slowing down the atherosclerosis process crucial to angina development. Additionally, zinc's effects may relate to its ability to inhibit inflammatory markers, which are often elevated in older adults.
Read More
7
We observed the effects of zinc on patients suffering from angina pectoris, a type of chest pain associated with coronary heart disease. In a study involving 31 participants, we measured changes in plasma zinc, copper, and erythrocyte glutathione peroxidase (GSH-Px) levels before and after a month of treatment with Kuo-Guan granule.
Before treatment, we found that the levels of zinc in patients were significantly lower, while copper levels were higher compared to those in a normal control group. After one month of treatment, there was an increase in plasma zinc levels and GSH-Px, along with a decrease in copper levels. These changes were statistically significant, indicating that the treatment helped regulate these trace elements in the patients' bodies.
However, it is essential to note that while we saw improvements in plasma zinc and GSH-Px levels, the effectiveness of zinc specifically as a standalone treatment for angina cannot be fully determined, as it was part of a combined treatment regimen with Kuo-Guan granule. The findings suggest a potential role of zinc in treatment, but more research focused solely on zinc would be needed to clarify its individual benefits in angina management.
Before treatment, we found that the levels of zinc in patients were significantly lower, while copper levels were higher compared to those in a normal control group. After one month of treatment, there was an increase in plasma zinc levels and GSH-Px, along with a decrease in copper levels. These changes were statistically significant, indicating that the treatment helped regulate these trace elements in the patients' bodies.
However, it is essential to note that while we saw improvements in plasma zinc and GSH-Px levels, the effectiveness of zinc specifically as a standalone treatment for angina cannot be fully determined, as it was part of a combined treatment regimen with Kuo-Guan granule. The findings suggest a potential role of zinc in treatment, but more research focused solely on zinc would be needed to clarify its individual benefits in angina management.
Read More
Most Useful Reviews
9
Reduced chest pains
36 people found this helpful
Reduced chest pains from angina. I've been taking this for 3 weeks, ranging from 2 to 4 doses of 50mg daily. I noticed when using my petrol-powered strimmer that my angina pain diminished. Previously, I would experience severe chest pains while mowing and had to pause until my heart rate decreased. Zinc aids red blood cells in oxygen transport, resolving some issues with angina caused by restricted blood flow. My angina attacks often stem from anxiety linked to physical or emotional stress, which causes pain radiating down my arm. The combination of Zinc with Benfotiamine, R-ALA, L-Carnitine, and L-Arginine enables me to exercise more freely. I learned about Zinc Gluconate from a study, where one participant’s angina disappeared, allowing him to ski again. Now, I’m convinced!
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
- All Researches
9
We explored the effects of high-dose zinc treatment on angina pectoris, particularly in patients suffering from severe atherosclerotic disease. This study reviewed existing literature and focused on how zinc might help reduce symptoms associated with this condition.
Zinc plays a crucial role in fighting oxidative stress, which is known to be a key player in arteriosclerosis and subsequent angina. Our observations indicated that when patients were given high doses of zinc sulfate, increasing their serum zinc levels significantly, many experienced notable improvements in their angina symptoms.
In fact, 12 out of 16 patients reported better outcomes after treatment. Moreover, it was found that long-term exposure to zinc in the environment appeared to lower incidences of exertional angina, reinforcing the idea that zinc could be beneficial.
We hypothesize that zinc may help prevent the oxidation of harmful LDL cholesterol, therefore slowing down the atherosclerosis process crucial to angina development. Additionally, zinc's effects may relate to its ability to inhibit inflammatory markers, which are often elevated in older adults.
Zinc plays a crucial role in fighting oxidative stress, which is known to be a key player in arteriosclerosis and subsequent angina. Our observations indicated that when patients were given high doses of zinc sulfate, increasing their serum zinc levels significantly, many experienced notable improvements in their angina symptoms.
In fact, 12 out of 16 patients reported better outcomes after treatment. Moreover, it was found that long-term exposure to zinc in the environment appeared to lower incidences of exertional angina, reinforcing the idea that zinc could be beneficial.
We hypothesize that zinc may help prevent the oxidation of harmful LDL cholesterol, therefore slowing down the atherosclerosis process crucial to angina development. Additionally, zinc's effects may relate to its ability to inhibit inflammatory markers, which are often elevated in older adults.
Read More
7
We observed the effects of zinc on patients suffering from angina pectoris, a type of chest pain associated with coronary heart disease. In a study involving 31 participants, we measured changes in plasma zinc, copper, and erythrocyte glutathione peroxidase (GSH-Px) levels before and after a month of treatment with Kuo-Guan granule.
Before treatment, we found that the levels of zinc in patients were significantly lower, while copper levels were higher compared to those in a normal control group. After one month of treatment, there was an increase in plasma zinc levels and GSH-Px, along with a decrease in copper levels. These changes were statistically significant, indicating that the treatment helped regulate these trace elements in the patients' bodies.
However, it is essential to note that while we saw improvements in plasma zinc and GSH-Px levels, the effectiveness of zinc specifically as a standalone treatment for angina cannot be fully determined, as it was part of a combined treatment regimen with Kuo-Guan granule. The findings suggest a potential role of zinc in treatment, but more research focused solely on zinc would be needed to clarify its individual benefits in angina management.
Before treatment, we found that the levels of zinc in patients were significantly lower, while copper levels were higher compared to those in a normal control group. After one month of treatment, there was an increase in plasma zinc levels and GSH-Px, along with a decrease in copper levels. These changes were statistically significant, indicating that the treatment helped regulate these trace elements in the patients' bodies.
However, it is essential to note that while we saw improvements in plasma zinc and GSH-Px levels, the effectiveness of zinc specifically as a standalone treatment for angina cannot be fully determined, as it was part of a combined treatment regimen with Kuo-Guan granule. The findings suggest a potential role of zinc in treatment, but more research focused solely on zinc would be needed to clarify its individual benefits in angina management.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
Reduced chest pains
36 people found this helpful
Reduced chest pains from angina. I've been taking this for 3 weeks, ranging from 2 to 4 doses of 50mg daily. I noticed when using my petrol-powered strimmer that my angina pain diminished. Previously, I would experience severe chest pains while mowing and had to pause until my heart rate decreased. Zinc aids red blood cells in oxygen transport, resolving some issues with angina caused by restricted blood flow. My angina attacks often stem from anxiety linked to physical or emotional stress, which causes pain radiating down my arm. The combination of Zinc with Benfotiamine, R-ALA, L-Carnitine, and L-Arginine enables me to exercise more freely. I learned about Zinc Gluconate from a study, where one participant’s angina disappeared, allowing him to ski again. Now, I’m convinced!
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Eby GA, Halcomb WW. High-dose zinc to terminate angina pectoris: a review and hypothesis for action by ICAM inhibition. Med Hypotheses. 2006;66:169.
- Li Y, Che J, Bao F. [Effects of kuo-guan granule on plasma zinc, copper and erythrocyte GSH-Px (glutathione peroxidase) in patients with angina pectoris]. Zhong Xi Yi Jie He Za Zhi. 1990;10:348.
