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SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.2
USERS' SCORE
Good
Based on 3 Reviews
8.6
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Zinc(from 270 mg Zinc Picolinate)
50 mg
455%
Top Medical Research Studies
8
Zinc alleviates arthritis symptoms
Therapeutic Dose of Zinc Aspartate and Zinc Citrate Attenuates Disease Activity Indices in Rheumatoid Arthritis.
Highly relevant to arthritis treatment
We explored the effects of zinc supplements—specifically zinc aspartate and zinc citrate—on reducing the symptoms of rheumatoid arthritis. In our study, we induced arthritis in male Wistar rats using a collagen-related method and then treated the rats with these zinc compounds over a four-week period. Our objective was to evaluate how these compounds could impact the disease's severity and markers associated with rheumatoid arthritis.
The results were quite promising. Both zinc aspartate and zinc citrate, administered at a therapeutic dose of 50 mg of elemental zinc per day, showed a significant reduction in the clinical symptoms associated with arthritis. Furthermore, these compounds displayed antibacterial properties against Escherichia coli, which is notable since rheumatoid arthritis patients often suffer from increased sensitivity to bacterial infections.
Importantly, we found no adverse effects on liver or kidney function in the rats that received the zinc treatment. This highlights the potential of zinc compounds not only as anti-inflammatory agents but also as preventive measures against microbial growth that can complicate rheumatoid arthritis.
The results were quite promising. Both zinc aspartate and zinc citrate, administered at a therapeutic dose of 50 mg of elemental zinc per day, showed a significant reduction in the clinical symptoms associated with arthritis. Furthermore, these compounds displayed antibacterial properties against Escherichia coli, which is notable since rheumatoid arthritis patients often suffer from increased sensitivity to bacterial infections.
Importantly, we found no adverse effects on liver or kidney function in the rats that received the zinc treatment. This highlights the potential of zinc compounds not only as anti-inflammatory agents but also as preventive measures against microbial growth that can complicate rheumatoid arthritis.
Read More
7
Zinc may reduce DNA damage
Oxidative DNA Damage and Zinc Status in Patients With Rheumatoid Arthritis in Duhok, Iraq.
Study directly explores zinc's role
This study investigated how zinc levels relate to arthritis severity and oxidative DNA damage among individuals with rheumatoid arthritis. We gathered data from 264 patients and 192 healthy individuals to understand the interplay between zinc levels, disease activity, and oxidative stress markers like 8-hydroxy-2-deoxyguanosine (8-OHdG).
Our findings revealed that patients with rheumatoid arthritis had notably higher levels of 8-OHdG, which indicates increased oxidative DNA damage. Alarmingly, these patients also exhibited lower zinc levels compared to the healthy group. Those with diminished zinc levels showed even more significant DNA damage than those with normal zinc levels.
Additionally, we noticed that patients with lower disease activity experienced less oxidative DNA damage. Interestingly, there was a significant negative correlation between serum zinc levels and disease activity scores, suggesting that higher zinc levels may be linked to better disease management. Thus, it seems that maintaining adequate zinc levels could be crucial for reducing oxidative stress and damage in rheumatoid arthritis patients.
Our findings revealed that patients with rheumatoid arthritis had notably higher levels of 8-OHdG, which indicates increased oxidative DNA damage. Alarmingly, these patients also exhibited lower zinc levels compared to the healthy group. Those with diminished zinc levels showed even more significant DNA damage than those with normal zinc levels.
Additionally, we noticed that patients with lower disease activity experienced less oxidative DNA damage. Interestingly, there was a significant negative correlation between serum zinc levels and disease activity scores, suggesting that higher zinc levels may be linked to better disease management. Thus, it seems that maintaining adequate zinc levels could be crucial for reducing oxidative stress and damage in rheumatoid arthritis patients.
Read More
9
Zinc nanoparticles aid gout treatment
A novel zinc ferrite nanoparticle protects against MSU-induced gout arthritis via Nrf2/NF-κB/NLRP3 pathway.
Directly investigates zinc's effects
We explored the potential benefits of a new treatment involving zinc ferrite nanoparticles (ZFN) for individuals suffering from gouty arthritis (GA). This form of arthritis can be painful and complex, affecting people of all ages. Traditional treatments often come with side effects, prompting a search for more effective and safer alternatives.
The study revealed that zinc ferrite nanoparticles have impressive anti-inflammatory and antioxidant properties, which can help in managing the symptoms of gouty arthritis. Through a combination of laboratory and animal studies, we observed that ZFN significantly reduced inflammation and oxidative stress. Interestingly, it appears to work by modifying critical pathways involved in inflammation, specifically by influencing the NF-κB pathway and the NLRP3 inflammasome, while also activating the Nrf2 pathway.
These findings suggest that ZFN could become a promising option for treating gouty arthritis, providing an innovative and biocompatible approach to therapy. By addressing inflammation at its source, zinc ferrite nanoparticles could offer a new ray of hope for those dealing with GA, showcasing the potential for nanotechnology in improving health outcomes.
The study revealed that zinc ferrite nanoparticles have impressive anti-inflammatory and antioxidant properties, which can help in managing the symptoms of gouty arthritis. Through a combination of laboratory and animal studies, we observed that ZFN significantly reduced inflammation and oxidative stress. Interestingly, it appears to work by modifying critical pathways involved in inflammation, specifically by influencing the NF-κB pathway and the NLRP3 inflammasome, while also activating the Nrf2 pathway.
These findings suggest that ZFN could become a promising option for treating gouty arthritis, providing an innovative and biocompatible approach to therapy. By addressing inflammation at its source, zinc ferrite nanoparticles could offer a new ray of hope for those dealing with GA, showcasing the potential for nanotechnology in improving health outcomes.
Read More
Most Useful Reviews
9.5
Improved sleep
I purchased these vitamins to strengthen my immune system and support my joints, as I suffer from arthritis. I have recently started taking them and have noticed no negative effects. My sleep has improved, and there’s new hair growth in bald patches. Overall, I’m pleased with the vitamins and would recommend them for arthritis.
Read More
8.8
Joint support
I take this zinc after listening to Dr. Berg, one capsule a day for arthritis alongside my main treatment. My brother also takes it as he trains intensively. I find it beneficial.
Read More
8
Enhanced immunity
מצוין! This product is excellent, with the right dosage and quality, and is beneficial for immunity. I have taken it for arthritis.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.2
9
Zinc nanoparticles aid gout treatment
A novel zinc ferrite nanoparticle protects against MSU-induced gout arthritis via Nrf2/NF-κB/NLRP3 pathway.
Directly investigates zinc's effects
We explored the potential benefits of a new treatment involving zinc ferrite nanoparticles (ZFN) for individuals suffering from gouty arthritis (GA). This form of arthritis can be painful and complex, affecting people of all ages. Traditional treatments often come with side effects, prompting a search for more effective and safer alternatives.
The study revealed that zinc ferrite nanoparticles have impressive anti-inflammatory and antioxidant properties, which can help in managing the symptoms of gouty arthritis. Through a combination of laboratory and animal studies, we observed that ZFN significantly reduced inflammation and oxidative stress. Interestingly, it appears to work by modifying critical pathways involved in inflammation, specifically by influencing the NF-κB pathway and the NLRP3 inflammasome, while also activating the Nrf2 pathway.
These findings suggest that ZFN could become a promising option for treating gouty arthritis, providing an innovative and biocompatible approach to therapy. By addressing inflammation at its source, zinc ferrite nanoparticles could offer a new ray of hope for those dealing with GA, showcasing the potential for nanotechnology in improving health outcomes.
The study revealed that zinc ferrite nanoparticles have impressive anti-inflammatory and antioxidant properties, which can help in managing the symptoms of gouty arthritis. Through a combination of laboratory and animal studies, we observed that ZFN significantly reduced inflammation and oxidative stress. Interestingly, it appears to work by modifying critical pathways involved in inflammation, specifically by influencing the NF-κB pathway and the NLRP3 inflammasome, while also activating the Nrf2 pathway.
These findings suggest that ZFN could become a promising option for treating gouty arthritis, providing an innovative and biocompatible approach to therapy. By addressing inflammation at its source, zinc ferrite nanoparticles could offer a new ray of hope for those dealing with GA, showcasing the potential for nanotechnology in improving health outcomes.
Read More
9
Zinc treatment shows promise for RA
Zinc oxide nanoparticles-doped curcumin-assisted recovery of rheumatoid arthritis and antioxidant status in experimental rabbits.
Limited isolation of zinc effects
We explored the potential benefits of zinc oxide nanoparticles combined with curcumin in aiding recovery from rheumatoid arthritis (RA) in experimental rabbits. The study began by inducing RA in the rabbits with a specific solution and then administering various treatments, including the mix of zinc and curcumin.
By analyzing blood samples from both control and treated rabbits, we observed the levels of important biological markers related to RA and antioxidant health. The outcomes were quite promising—after treatment, there was a notable reduction in markers indicative of RA, such as rheumatoid factor and C-reactive protein, indicating improved health in the treated rabbits.
Among the treatments, the zinc oxide nanoparticles-doped curcumin exhibited the most significant improvement by lowering markers of oxidative stress while enhancing antioxidant activity. This suggests that the combined therapy may be a viable option for managing RA, offering a new avenue in our ongoing search for effective treatments.
By analyzing blood samples from both control and treated rabbits, we observed the levels of important biological markers related to RA and antioxidant health. The outcomes were quite promising—after treatment, there was a notable reduction in markers indicative of RA, such as rheumatoid factor and C-reactive protein, indicating improved health in the treated rabbits.
Among the treatments, the zinc oxide nanoparticles-doped curcumin exhibited the most significant improvement by lowering markers of oxidative stress while enhancing antioxidant activity. This suggests that the combined therapy may be a viable option for managing RA, offering a new avenue in our ongoing search for effective treatments.
Read More
8
Zinc alleviates arthritis symptoms
Therapeutic Dose of Zinc Aspartate and Zinc Citrate Attenuates Disease Activity Indices in Rheumatoid Arthritis.
Highly relevant to arthritis treatment
We explored the effects of zinc supplements—specifically zinc aspartate and zinc citrate—on reducing the symptoms of rheumatoid arthritis. In our study, we induced arthritis in male Wistar rats using a collagen-related method and then treated the rats with these zinc compounds over a four-week period. Our objective was to evaluate how these compounds could impact the disease's severity and markers associated with rheumatoid arthritis.
The results were quite promising. Both zinc aspartate and zinc citrate, administered at a therapeutic dose of 50 mg of elemental zinc per day, showed a significant reduction in the clinical symptoms associated with arthritis. Furthermore, these compounds displayed antibacterial properties against Escherichia coli, which is notable since rheumatoid arthritis patients often suffer from increased sensitivity to bacterial infections.
Importantly, we found no adverse effects on liver or kidney function in the rats that received the zinc treatment. This highlights the potential of zinc compounds not only as anti-inflammatory agents but also as preventive measures against microbial growth that can complicate rheumatoid arthritis.
The results were quite promising. Both zinc aspartate and zinc citrate, administered at a therapeutic dose of 50 mg of elemental zinc per day, showed a significant reduction in the clinical symptoms associated with arthritis. Furthermore, these compounds displayed antibacterial properties against Escherichia coli, which is notable since rheumatoid arthritis patients often suffer from increased sensitivity to bacterial infections.
Importantly, we found no adverse effects on liver or kidney function in the rats that received the zinc treatment. This highlights the potential of zinc compounds not only as anti-inflammatory agents but also as preventive measures against microbial growth that can complicate rheumatoid arthritis.
Read More
8
Zinc intake may aid bone health
The association between dietary zinc intake and osteopenia, osteoporosis in patients with rheumatoid arthritis.
Directly focused on dietary effects
We explored the relationship between dietary zinc intake and the development of osteopenia and osteoporosis in patients with rheumatoid arthritis (RA). Utilizing data from a well-known health and nutrition survey, we employed statistical methods to determine if higher zinc intake could lead to better bone health outcomes for those suffering from RA.
Our findings revealed an interesting trend: higher dietary zinc intake seems to be linked with a lower incidence of osteopenia and osteoporosis in these patients. This suggests that adequate zinc may play a protective role when it comes to bone density and overall health for individuals with RA.
However, we believe that more comprehensive studies, including randomized trials, are needed to further validate these results and uncover the mechanisms at work. For now, it appears that ensuring sufficient zinc in the diet could potentially benefit bone health in those dealing with this chronic condition.
Our findings revealed an interesting trend: higher dietary zinc intake seems to be linked with a lower incidence of osteopenia and osteoporosis in these patients. This suggests that adequate zinc may play a protective role when it comes to bone density and overall health for individuals with RA.
However, we believe that more comprehensive studies, including randomized trials, are needed to further validate these results and uncover the mechanisms at work. For now, it appears that ensuring sufficient zinc in the diet could potentially benefit bone health in those dealing with this chronic condition.
Read More
7
Zinc may reduce DNA damage
Oxidative DNA Damage and Zinc Status in Patients With Rheumatoid Arthritis in Duhok, Iraq.
Study directly explores zinc's role
This study investigated how zinc levels relate to arthritis severity and oxidative DNA damage among individuals with rheumatoid arthritis. We gathered data from 264 patients and 192 healthy individuals to understand the interplay between zinc levels, disease activity, and oxidative stress markers like 8-hydroxy-2-deoxyguanosine (8-OHdG).
Our findings revealed that patients with rheumatoid arthritis had notably higher levels of 8-OHdG, which indicates increased oxidative DNA damage. Alarmingly, these patients also exhibited lower zinc levels compared to the healthy group. Those with diminished zinc levels showed even more significant DNA damage than those with normal zinc levels.
Additionally, we noticed that patients with lower disease activity experienced less oxidative DNA damage. Interestingly, there was a significant negative correlation between serum zinc levels and disease activity scores, suggesting that higher zinc levels may be linked to better disease management. Thus, it seems that maintaining adequate zinc levels could be crucial for reducing oxidative stress and damage in rheumatoid arthritis patients.
Our findings revealed that patients with rheumatoid arthritis had notably higher levels of 8-OHdG, which indicates increased oxidative DNA damage. Alarmingly, these patients also exhibited lower zinc levels compared to the healthy group. Those with diminished zinc levels showed even more significant DNA damage than those with normal zinc levels.
Additionally, we noticed that patients with lower disease activity experienced less oxidative DNA damage. Interestingly, there was a significant negative correlation between serum zinc levels and disease activity scores, suggesting that higher zinc levels may be linked to better disease management. Thus, it seems that maintaining adequate zinc levels could be crucial for reducing oxidative stress and damage in rheumatoid arthritis patients.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.6
9.5
Improved sleep
I purchased these vitamins to strengthen my immune system and support my joints, as I suffer from arthritis. I have recently started taking them and have noticed no negative effects. My sleep has improved, and there’s new hair growth in bald patches. Overall, I’m pleased with the vitamins and would recommend them for arthritis.
Read More
8.8
Joint support
I take this zinc after listening to Dr. Berg, one capsule a day for arthritis alongside my main treatment. My brother also takes it as he trains intensively. I find it beneficial.
8
Enhanced immunity
מצוין! This product is excellent, with the right dosage and quality, and is beneficial for immunity. I have taken it for arthritis.
