Medical Researches
Moderately Effective
Based on 7 Researches
We observed a unique case involving an 11-year-old boy who presented with two skin conditions: Acrodermatitis Enteropathica (AcE) and eczema herpeticum, both in the context of his atopic dermatitis. The findings detailed how these conditions manifested with periorificial erosions and itchy vesicles. The boy's situation highlights the complexity of treating skin infections in those already suffering from eczema.
In managing his conditions, we provided treatment that included oral zinc supplementation along with acyclovir, an antiviral medication. What’s particularly interesting is that within just two weeks of starting this combination therapy, the boy experienced complete resolution of his symptoms. While the effectiveness of zinc cannot be isolated from the acyclovir, the rapid improvement does suggest potential benefits in its role when treating skin issues linked with herpes and eczema.
Our findings support the idea that zinc, alongside traditional antiviral treatments, may play a useful part in addressing skin ailments in children with eczema. This reinforces the importance of considering zinc as a complementary approach in managing similar cases in the future.
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Zinc cream shows promise for eczemaMaintenance of an Acidic Skin Surface with a Novel Zinc Lactobionate Emollient Preparation Improves Skin Barrier Function in Patients with Atopic Dermatitis.
Good relevance to skin health.
We conducted a double-blind, forearm-controlled study to investigate how a novel emollient cream containing zinc lactobionate could improve skin health in patients suffering from atopic dermatitis (eczema). The primary objectives were to find out if this cream could lower the skin's surface pH and enhance the skin barrier function.
Over the course of 56 days, 23 adults with eczema applied the study cream to one forearm and a control cream to the other. By the end of the trial, we observed that the areas treated with the zinc cream had a significantly lower pH compared to the control areas. This shift toward a healthier pH level was linked to better hydration and reduced skin sensitivity, alongside decreased transepidermal water loss (TEWL).
Overall, maintaining an acidic skin pH and utilizing zinc's emollient properties seem to help in managing eczema, making the skin less sensitive to irritants and allergens. Our findings point to a positive effect of zinc lactobionate in supporting the skin barrier for those with eczema, offering a promising avenue for skincare treatments.
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We investigated the relationship between zinc deficiency and eczema in a 3-month-old infant who was exclusively breastfed. The infant presented with symptoms like scaling erythematous dermatitis affecting her face and other areas, alongside irritability and poor weight gain. Her mother had been taking isoniazid for tuberculosis during pregnancy, which possibly contributed to the infant’s zinc deficiency.
After initial treatments for a suspected skin infection didn’t bring any changes, we found that the baby had low serum zinc levels and low zinc concentration in her breast milk. This led us to believe the skin condition was due to zinc deficiency rather than an infection. We started zinc supplementation, and the infant showed remarkable improvement in her skin condition and weight.
By 6 months, the infant had begun eating solid food, and we stopped the zinc supplements, with no signs of eczema returning. This case underscores the importance of monitoring zinc levels in breastfed infants, especially when mothers are on specific medications that might impact nutrient transfer through breast milk.
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Zinc intake linked to eczemaAssociation between dietary antioxidants intake and childhood eczema: results from the NHANES database.
Direct focus on zinc's effects
We explored the relationship between dietary zinc intake and childhood eczema using data from a large national health survey. Our focus was on understanding whether higher levels of zinc could positively influence eczema symptoms in children and adolescents under 18 years old.
We found that among the participants, which included 2305 children, about 11.6% were reported to have eczema. Our analysis revealed that those with higher dietary zinc intake, specifically those consuming at least 11.83 mg of zinc per day, had lower chances of experiencing eczema compared to those with lower zinc intake. The odds ratio indicated that these children were 55% less likely to have eczema, suggesting a potential protective effect from dietary zinc.
Particularly interesting was our subgroup analysis, which highlighted that younger children aged 1 to 11 years, regardless of gender, appeared to benefit the most from increased zinc intake. While we did not observe significant associations for other dietary antioxidants like β-carotene or vitamin C, the implications of zinc intake are noteworthy.
Overall, our findings point to dietary zinc as a potentially valuable component in managing childhood eczema, paving the way for future research to further clarify these effects and their mechanisms.
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Zinc bolus improves serum levelsComparison of a novel form of zinc with zinc oxide bolus licensed for prevention of facial eczema, and interaction with copper oxide in sheep.
Limited relevance due to copper interaction
We explored how a new form of zinc, an elemental zinc bolus, affects sheep in potentially preventing facial eczema, specifically by comparing it to a well-established zinc oxide bolus. In our study, we used a 2×2 factorial design with 40 Romney-cross ewes divided into groups receiving either the novel zinc treatment or the zinc oxide control.
To assess any interactions with copper, we also administered a capsule containing copper oxide to half of the animals in each zinc group. Over the course of several weeks, we monitored the sheep for signs of photosensitization and collected samples to measure serum zinc concentrations, among other variables.
Our findings revealed that serum zinc levels were significantly higher in the group treated with the novel elemental zinc compared to the zinc oxide group. This increase was consistently observed over time, and we found a positive correlation between serum zinc and fecal zinc concentrations. Interestingly, the copper treatment did not appear to have an impact on zinc levels, nor did it change liver copper concentrations in the different zinc treatment groups.
Overall, the study indicates that the new elemental zinc bolus can elevate serum zinc levels in sheep, which may help in preventing facial eczema. However, it also highlights that interactions with copper do not significantly affect zinc absorption or effectiveness.
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User Reviews
This product helps control my eczema effectively. I take 1-2 daily for my lifelong eczema, and it's quite beneficial. When consuming citrus fruits and tomatoes, my eczema flares up, but by taking 2 10mg famotidine tablets alongside these foods, the acid is neutralised, preventing me from looking like I've been scrubbed with a brillo pad the next day.
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I take it once every few days, as I believe it’s not good to take too much. It’s small and easy to swallow. My scalp eczema, which I’ve suffered for years, has improved, and I want to continue taking it.
I started taking this to alleviate an itchy flare. Taking it with probiotics really works!
I take this with other vitamin C supplements, and the eczema on my hands has improved significantly. My immunity feels stronger, and I want to keep taking it daily as I feel uneasy when I don’t.
Eczema control maintained
Regular use of this product helps manage my itching and eczema breakouts effectively. I appreciate that it comes in Veg Capsules.