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SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.7
USERS' SCORE
Moderately Good
Based on 1 Review
7.7
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Zinc(from 270 mg Zinc Picolinate)
50 mg
455%
Top Medical Research Studies
8
Zinc-Infused Catheters Reduce Infections
Antimicrobial and Antibiofilm Activities of Urinary Catheter Incorporated with ZnO-Carbon Nanotube.
High relevance to zinc's effectiveness
We investigated the potential of a new type of urinary catheter to tackle catheter-associated urinary tract infections (CAUTIs). By incorporating zinc oxide-carbon nanotubes (ZnO-CNT) into a silicone catheter, we explored how this innovative design could inhibit infection-causing bacteria effectively.
Utilizing a combination of laboratory techniques like scanning electron microscopy and dynamic light scattering, we analyzed the structure of our ZnO-CNT catheter, which showed promising antibacterial properties. Notably, we found that the ZnO-CNT infusion significantly reduced biofilm formation—one of the main challenges in urinary catheters—demonstrating up to 56% inhibition in bacterial growth compared to standard silicone catheters.
The study revealed that ZnO-CNT not only holds antimicrobial potential but may also provide a more comfortable alternative to existing metal-coated options, like those using silver or gold. With our findings, we hope to present a viable strategy for reducing the discomfort and risks associated with traditional catheters while addressing a prevalent healthcare concern.
Utilizing a combination of laboratory techniques like scanning electron microscopy and dynamic light scattering, we analyzed the structure of our ZnO-CNT catheter, which showed promising antibacterial properties. Notably, we found that the ZnO-CNT infusion significantly reduced biofilm formation—one of the main challenges in urinary catheters—demonstrating up to 56% inhibition in bacterial growth compared to standard silicone catheters.
The study revealed that ZnO-CNT not only holds antimicrobial potential but may also provide a more comfortable alternative to existing metal-coated options, like those using silver or gold. With our findings, we hope to present a viable strategy for reducing the discomfort and risks associated with traditional catheters while addressing a prevalent healthcare concern.
Read More
9
Zinc nanoparticle effectiveness confirmed
Antimicrobial efficacy of Mentha piperata-derived biogenic zinc oxide nanoparticles against UTI-resistant pathogens.
Promising against UTI pathogens
We investigated the potential of zinc oxide nanoparticles (ZnO NPs) derived from Mentha piperata, aiming to tackle urinary tract infections (UTIs) caused by antibiotic-resistant pathogens. Our study utilized an agar well diffusion assay to assess the effectiveness of these biogenic nanoparticles against notable bacteria, including Proteus mirabilis and Pseudomonas aeruginosa, as well as the fungal strain Candida albicans.
The results were promising; we found that the ZnO NPs showed significantly higher inhibition of these pathogens compared to conventional synthetic antibiotics. Interestingly, the zinc nanoparticles alone outperformed combinations with plant extracts. The analysis tools we used, including UV-Vis spectroscopy and scanning electron microscopy (SEM), indicated that the nanoparticles have a well-defined structure and favorable properties for attacking the bacteria.
As we dived deeper into the mechanisms, it appeared that higher concentrations of ZnO NPs triggered oxidative stress in the pathogen's cells. This interaction may damage the cell membrane, resulting in cell death and confirming their excellent dose-dependent antimicrobial effects against UTI-causing microorganisms. These findings highlight the potential of utilizing natural sources for developing new antimicrobial solutions to combat resistant infections.
The results were promising; we found that the ZnO NPs showed significantly higher inhibition of these pathogens compared to conventional synthetic antibiotics. Interestingly, the zinc nanoparticles alone outperformed combinations with plant extracts. The analysis tools we used, including UV-Vis spectroscopy and scanning electron microscopy (SEM), indicated that the nanoparticles have a well-defined structure and favorable properties for attacking the bacteria.
As we dived deeper into the mechanisms, it appeared that higher concentrations of ZnO NPs triggered oxidative stress in the pathogen's cells. This interaction may damage the cell membrane, resulting in cell death and confirming their excellent dose-dependent antimicrobial effects against UTI-causing microorganisms. These findings highlight the potential of utilizing natural sources for developing new antimicrobial solutions to combat resistant infections.
Read More
9
Zinc-nanoparticle synergy combats UTIs
Synergistic Antibacterial Potential of 6-Pentyl-α-pyrone Lactone and Zinc Oxide Nanoparticles against Multidrug-Resistant Isolated from Urinary Tract Infections in Humans.
Relevant use of zinc in UTIs
We explored the antibacterial properties of zinc oxide nanoparticles (ZnONPs) and a natural compound called 6-pentyl-α-pyrone lactone against multidrug-resistant bacteria causing urinary tract infections (UTIs). Our study involved analyzing urine samples from humans to identify the presence of these bacteria and assess their resistance to multiple antibiotics.
The results showed that a significant portion of the samples tested positive for bacteria, with a particularly high prevalence of **E. coli**. Alarmingly, nearly all isolated strains demonstrated multidrug resistance, which poses a serious challenge for treatment. Our investigation revealed that the combination of ZnONPs and 6-pentyl-α-pyrone lactone enhanced their antibacterial effects. Particularly, we observed a substantial reduction in the minimum inhibitory concentration (MIC) for both substances when used together.
This combination therapy highlighted a promising avenue for addressing antibiotic resistance in UTIs. The study suggests that integrating ZnONPs with natural compounds could serve as a valuable strategy in combating these tough infections. However, more research is needed to fully understand the mechanisms at play and to evaluate this treatment in clinical settings.
The results showed that a significant portion of the samples tested positive for bacteria, with a particularly high prevalence of **E. coli**. Alarmingly, nearly all isolated strains demonstrated multidrug resistance, which poses a serious challenge for treatment. Our investigation revealed that the combination of ZnONPs and 6-pentyl-α-pyrone lactone enhanced their antibacterial effects. Particularly, we observed a substantial reduction in the minimum inhibitory concentration (MIC) for both substances when used together.
This combination therapy highlighted a promising avenue for addressing antibiotic resistance in UTIs. The study suggests that integrating ZnONPs with natural compounds could serve as a valuable strategy in combating these tough infections. However, more research is needed to fully understand the mechanisms at play and to evaluate this treatment in clinical settings.
Read More
Most Useful Reviews
0
Severe side effects
I experienced a dangerous dosage after taking one capsule daily for two weeks, leading to severe urinary tract infection and diarrhoea. This supplement contains almost five times the recommended daily intake of zinc for an adult woman (8 mg). Please exercise caution!
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.7
9.5
Zinc enhances catheter antimicrobial effects
Dual-Layer Nanoengineered Urinary Catheters for Enhanced Antimicrobial Efficacy and Reduced Cytotoxicity.
Evaluates combined zinc and silver
We focused on a new approach to tackle urinary tract infections (UTIs), a common issue many people face, particularly from catheters. This study introduced a dual-layer catheter design that combines zinc and silver nanoparticles to enhance antibacterial properties while minimizing potential harm to human cells. The zinc layer works alongside silver to not only provide an immediate defense against bacteria but also ensures a controlled release of silver over time.
Our findings showed that the zinc and silver combination effectively fought off UTI pathogens, with reductions of up to 99.9% for E. coli and 99.7% for S. aureus. This dual-layer approach significantly outperformed both regular silver-coated and uncoated catheters, particularly in limiting biofilm formation and inflammation in a rabbit model. So, while zinc alone isn't the primary focus here, its presence alongside silver appears crucial in enhancing the overall effectiveness of the catheter technology.
Although further studies are needed, this innovative strategy shows promise for improving long-term solutions in preventing catheter-associated urinary tract infections.
Our findings showed that the zinc and silver combination effectively fought off UTI pathogens, with reductions of up to 99.9% for E. coli and 99.7% for S. aureus. This dual-layer approach significantly outperformed both regular silver-coated and uncoated catheters, particularly in limiting biofilm formation and inflammation in a rabbit model. So, while zinc alone isn't the primary focus here, its presence alongside silver appears crucial in enhancing the overall effectiveness of the catheter technology.
Although further studies are needed, this innovative strategy shows promise for improving long-term solutions in preventing catheter-associated urinary tract infections.
Read More
9
Zinc nanoparticle effectiveness confirmed
Antimicrobial efficacy of Mentha piperata-derived biogenic zinc oxide nanoparticles against UTI-resistant pathogens.
Promising against UTI pathogens
We investigated the potential of zinc oxide nanoparticles (ZnO NPs) derived from Mentha piperata, aiming to tackle urinary tract infections (UTIs) caused by antibiotic-resistant pathogens. Our study utilized an agar well diffusion assay to assess the effectiveness of these biogenic nanoparticles against notable bacteria, including Proteus mirabilis and Pseudomonas aeruginosa, as well as the fungal strain Candida albicans.
The results were promising; we found that the ZnO NPs showed significantly higher inhibition of these pathogens compared to conventional synthetic antibiotics. Interestingly, the zinc nanoparticles alone outperformed combinations with plant extracts. The analysis tools we used, including UV-Vis spectroscopy and scanning electron microscopy (SEM), indicated that the nanoparticles have a well-defined structure and favorable properties for attacking the bacteria.
As we dived deeper into the mechanisms, it appeared that higher concentrations of ZnO NPs triggered oxidative stress in the pathogen's cells. This interaction may damage the cell membrane, resulting in cell death and confirming their excellent dose-dependent antimicrobial effects against UTI-causing microorganisms. These findings highlight the potential of utilizing natural sources for developing new antimicrobial solutions to combat resistant infections.
The results were promising; we found that the ZnO NPs showed significantly higher inhibition of these pathogens compared to conventional synthetic antibiotics. Interestingly, the zinc nanoparticles alone outperformed combinations with plant extracts. The analysis tools we used, including UV-Vis spectroscopy and scanning electron microscopy (SEM), indicated that the nanoparticles have a well-defined structure and favorable properties for attacking the bacteria.
As we dived deeper into the mechanisms, it appeared that higher concentrations of ZnO NPs triggered oxidative stress in the pathogen's cells. This interaction may damage the cell membrane, resulting in cell death and confirming their excellent dose-dependent antimicrobial effects against UTI-causing microorganisms. These findings highlight the potential of utilizing natural sources for developing new antimicrobial solutions to combat resistant infections.
Read More
9
Zinc-nanoparticle synergy combats UTIs
Synergistic Antibacterial Potential of 6-Pentyl-α-pyrone Lactone and Zinc Oxide Nanoparticles against Multidrug-Resistant Isolated from Urinary Tract Infections in Humans.
Relevant use of zinc in UTIs
We explored the antibacterial properties of zinc oxide nanoparticles (ZnONPs) and a natural compound called 6-pentyl-α-pyrone lactone against multidrug-resistant bacteria causing urinary tract infections (UTIs). Our study involved analyzing urine samples from humans to identify the presence of these bacteria and assess their resistance to multiple antibiotics.
The results showed that a significant portion of the samples tested positive for bacteria, with a particularly high prevalence of **E. coli**. Alarmingly, nearly all isolated strains demonstrated multidrug resistance, which poses a serious challenge for treatment. Our investigation revealed that the combination of ZnONPs and 6-pentyl-α-pyrone lactone enhanced their antibacterial effects. Particularly, we observed a substantial reduction in the minimum inhibitory concentration (MIC) for both substances when used together.
This combination therapy highlighted a promising avenue for addressing antibiotic resistance in UTIs. The study suggests that integrating ZnONPs with natural compounds could serve as a valuable strategy in combating these tough infections. However, more research is needed to fully understand the mechanisms at play and to evaluate this treatment in clinical settings.
The results showed that a significant portion of the samples tested positive for bacteria, with a particularly high prevalence of **E. coli**. Alarmingly, nearly all isolated strains demonstrated multidrug resistance, which poses a serious challenge for treatment. Our investigation revealed that the combination of ZnONPs and 6-pentyl-α-pyrone lactone enhanced their antibacterial effects. Particularly, we observed a substantial reduction in the minimum inhibitory concentration (MIC) for both substances when used together.
This combination therapy highlighted a promising avenue for addressing antibiotic resistance in UTIs. The study suggests that integrating ZnONPs with natural compounds could serve as a valuable strategy in combating these tough infections. However, more research is needed to fully understand the mechanisms at play and to evaluate this treatment in clinical settings.
Read More
8
Zinc-Infused Catheters Reduce Infections
Antimicrobial and Antibiofilm Activities of Urinary Catheter Incorporated with ZnO-Carbon Nanotube.
High relevance to zinc's effectiveness
We investigated the potential of a new type of urinary catheter to tackle catheter-associated urinary tract infections (CAUTIs). By incorporating zinc oxide-carbon nanotubes (ZnO-CNT) into a silicone catheter, we explored how this innovative design could inhibit infection-causing bacteria effectively.
Utilizing a combination of laboratory techniques like scanning electron microscopy and dynamic light scattering, we analyzed the structure of our ZnO-CNT catheter, which showed promising antibacterial properties. Notably, we found that the ZnO-CNT infusion significantly reduced biofilm formation—one of the main challenges in urinary catheters—demonstrating up to 56% inhibition in bacterial growth compared to standard silicone catheters.
The study revealed that ZnO-CNT not only holds antimicrobial potential but may also provide a more comfortable alternative to existing metal-coated options, like those using silver or gold. With our findings, we hope to present a viable strategy for reducing the discomfort and risks associated with traditional catheters while addressing a prevalent healthcare concern.
Utilizing a combination of laboratory techniques like scanning electron microscopy and dynamic light scattering, we analyzed the structure of our ZnO-CNT catheter, which showed promising antibacterial properties. Notably, we found that the ZnO-CNT infusion significantly reduced biofilm formation—one of the main challenges in urinary catheters—demonstrating up to 56% inhibition in bacterial growth compared to standard silicone catheters.
The study revealed that ZnO-CNT not only holds antimicrobial potential but may also provide a more comfortable alternative to existing metal-coated options, like those using silver or gold. With our findings, we hope to present a viable strategy for reducing the discomfort and risks associated with traditional catheters while addressing a prevalent healthcare concern.
Read More
8
Zinc aids UTI recovery
Interventions for High-Burden Infectious Diseases in Children and Adolescents: A Meta-analysis.
Moderate relevance based on findings
We examined the effectiveness of zinc treatment for urinary tract infections, drawing from data that analyzed its effects among school-aged children and adolescents. The findings indicated that zinc supplementation can aid in faster recovery from urinary tract infections, showcasing a positive impact in alleviating symptoms.
Although there is promise in using zinc for UTI treatment, it's important to note that the information is somewhat limited. The research does not distinctly isolate zinc as the sole intervention, which makes it challenging to determine its effectiveness independently. Ultimately, while zinc appears to help in managing urinary tract infections, we need more specific studies to confirm its isolated benefits.
Therefore, while we see some encouraging results regarding zinc's role in improving recovery from UTIs, further research is essential to draw definitive conclusions. Especially, focusing on zinc's isolated benefits could provide clearer guidelines for its use in treatment protocols.
Although there is promise in using zinc for UTI treatment, it's important to note that the information is somewhat limited. The research does not distinctly isolate zinc as the sole intervention, which makes it challenging to determine its effectiveness independently. Ultimately, while zinc appears to help in managing urinary tract infections, we need more specific studies to confirm its isolated benefits.
Therefore, while we see some encouraging results regarding zinc's role in improving recovery from UTIs, further research is essential to draw definitive conclusions. Especially, focusing on zinc's isolated benefits could provide clearer guidelines for its use in treatment protocols.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 1 Review
7.7
0
Severe side effects
I experienced a dangerous dosage after taking one capsule daily for two weeks, leading to severe urinary tract infection and diarrhoea. This supplement contains almost five times the recommended daily intake of zinc for an adult woman (8 mg). Please exercise caution!
