'
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.6
USERS' SCORE
Good
Based on 1 Review
8.5
Supplement Facts
Serving Size:  2 Veg Capsules
Amount Per Serving
%DV
Magnesium (from Magnesium Aspartate)
250 mg
60%
Potassium (from Potassium Aspartate)
99 mg
2%
Taurine (Free-Form)
100 mg

Top Medical Research Studies

9.5
Magnesium reduces postoperative back pain
Effect of perioperative intravenous magnesium sulfate on postoperative pain after iliac venous stenting.
Direct relevance to magnesium use
We explored the effectiveness of magnesium sulfate (MS) in relieving low back pain (LBP) for patients who underwent iliac venous stenting. This study involved 97 patients, divided into two groups: one received MS infusion during their surgery, while the other did not.

Patients who received MS experienced significantly lower pain levels at all follow-up intervals. We found that, at 24 hours after surgery, those in the magnesium group consumed much less tramadol—a common pain medication—compared to the control group. Additionally, the need for extra pain relief was lower among those who received magnesium.

Importantly, the side effects like nausea and vomiting were similar in both groups, indicating that magnesium can be a safe option for pain management after this type of surgery. Overall, the findings suggest that magnesium sulfate not only alleviates pain but also reduces reliance on opioids, making it a valuable treatment for postoperative care.
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8
Taurine targets disc degeneration
Taurine rescues intervertebral disc degeneration by activating mitophagy through the PINK1/Parkin pathway.
Potential benefits for back pain
The study aimed to find out how taurine treatment could help with intervertebral disc degeneration (IDD), a common cause of debilitating back pain. Researchers conducted a series of in vitro and in vivo experiments that looked closely at taurine's effects on nucleus pulposus cells, which play a crucial role in spinal health.

We found that taurine not only boosts a process called mitophagy—important for cleaning up damaged mitochondria—but it also reduces oxidative stress and delays cell aging. By activating the PINK1/Parkin pathway, taurine appears to support healthier mitochondria, leading to improvements in disc health and possibly staving off degeneration.

Overall, these findings suggest that taurine may have significant protective effects against IDD, marking it as a potential therapeutic option for individuals suffering from back pain. This study opens up new avenues for treatment strategies targeting mitochondrial health in the management of back pain.
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9
Magnesium therapy aids back pain
A double-blinded randomised controlled study of the value of sequential intravenous and oral magnesium therapy in patients with chronic low back pain with a neuropathic component.
Explores magnesium's combined benefits
We conducted a double-blind study to evaluate the effectiveness of magnesium therapy for chronic low back pain that has a neuropathic component. Our research involved 80 patients, all of whom were already engaged in physical therapy and taking medications like anticonvulsants and antidepressants.

Among the participants, we divided them into two groups: one group received a placebo for six weeks, while the other group was treated with a two-week intravenous magnesium infusion followed by four weeks of oral magnesium supplements.

The results were promising for those in the magnesium group. By the end of the study, their pain intensity decreased significantly, with scores dropping from an average of 7.5 to 4.7 over six months. Additionally, we observed notable improvements in their lumbar spine mobility, suggesting that magnesium therapy could be beneficial for those suffering from this type of chronic pain.

Overall, our findings indicate that sequential intravenous and oral magnesium treatment can effectively ease pain and enhance mobility in individuals with refractory low back pain featuring a neuropathic aspect.
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Most Useful Reviews

8.8
Lowered arthritic pain
My blood pressure is back to normal after starting this supplement, and I have also experienced reduced arthritic pain in my hips, knees, and back.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.6
9.5
Magnesium reduces postoperative back pain
Effect of perioperative intravenous magnesium sulfate on postoperative pain after iliac venous stenting.
Direct relevance to magnesium use
We explored the effectiveness of magnesium sulfate (MS) in relieving low back pain (LBP) for patients who underwent iliac venous stenting. This study involved 97 patients, divided into two groups: one received MS infusion during their surgery, while the other did not.

Patients who received MS experienced significantly lower pain levels at all follow-up intervals. We found that, at 24 hours after surgery, those in the magnesium group consumed much less tramadol—a common pain medication—compared to the control group. Additionally, the need for extra pain relief was lower among those who received magnesium.

Importantly, the side effects like nausea and vomiting were similar in both groups, indicating that magnesium can be a safe option for pain management after this type of surgery. Overall, the findings suggest that magnesium sulfate not only alleviates pain but also reduces reliance on opioids, making it a valuable treatment for postoperative care.
Read More
9
Magnesium therapy aids back pain
A double-blinded randomised controlled study of the value of sequential intravenous and oral magnesium therapy in patients with chronic low back pain with a neuropathic component.
Explores magnesium's combined benefits
We conducted a double-blind study to evaluate the effectiveness of magnesium therapy for chronic low back pain that has a neuropathic component. Our research involved 80 patients, all of whom were already engaged in physical therapy and taking medications like anticonvulsants and antidepressants.

Among the participants, we divided them into two groups: one group received a placebo for six weeks, while the other group was treated with a two-week intravenous magnesium infusion followed by four weeks of oral magnesium supplements.

The results were promising for those in the magnesium group. By the end of the study, their pain intensity decreased significantly, with scores dropping from an average of 7.5 to 4.7 over six months. Additionally, we observed notable improvements in their lumbar spine mobility, suggesting that magnesium therapy could be beneficial for those suffering from this type of chronic pain.

Overall, our findings indicate that sequential intravenous and oral magnesium treatment can effectively ease pain and enhance mobility in individuals with refractory low back pain featuring a neuropathic aspect.
Read More
9
Taurine's impact on back pain
Novel analgesic combination of tramadol, paracetamol, caffeine and taurine in the management of moderate to moderately severe acute low back pain.
Moderate effectiveness noted, uncertain for taurine
We explored the effectiveness of a novel analgesic combination involving tramadol, paracetamol, caffeine, and taurine in managing moderate to moderately severe acute low back pain. This study compared this combination against a standard treatment of tramadol and paracetamol, engaging patients from 50 clinics across India.

Throughout the five-day trial, participants took one tablet every six hours. Results showed a strong preference for the new combination, with significantly more patients reporting effective pain relief and fewer adverse reactions. In fact, 81% of patients in the new drug group experienced good to excellent treatment satisfaction, compared to just 45% in the traditional treatment group.

While taurine is a component of this innovative mix, the individual impact of taurine on back pain alone isn't clearly established by this study. Instead, it contributed to the overall benefits seen when combined with other medications. Thus, we see that taurine plays a role, but its standalone effectiveness remains to be determined.
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8
Magnesium shows promise for IVDD
ROS-responsive magnesium-containing microspheres for antioxidative treatment of intervertebral disc degeneration.
Moderate relevance to magnesium treatment
We explored the potential of magnesium-containing microspheres to help manage intervertebral disc degeneration (IVDD), a condition often linked with back pain. This innovative treatment focuses on using microspheres that respond to reactive oxygen species, which are indicators of oxidative stress often seen in IVDD. By targeting these harmful agents, we aimed to reduce the associated inflammation and pain.

The microspheres, composed of a polymer shell and a magnesium core, work by releasing hydrogen gas in response to oxidative conditions, which can help neutralize damaging free radicals in the body. We observed significant improvements in a rat model of disc degeneration, which included less damage to the disc structure, reduced cell death, and overall better disc health.

The results of this study highlight magnesium's role as a key component in enhancing the antioxidative capacity of the treatment. This not only mitigates the effects of IVDD but also supports the idea that antioxidant therapies may hold promise for alleviating back pain. Importantly, we noted that this approach showed strong biocompatibility and minimal toxicity, making it a potential option for future clinical applications.
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8
Magnesium and back pain relief
Green exercise and mg-ca-SO thermal balneotherapy for the treatment of non-specific chronic low back pain: a randomized controlled clinical trial.
Moderate effectiveness observed
We conducted a study to explore how magnesium treatment and mountain hiking might alleviate non-specific chronic low back pain (nscLBP). In this randomized controlled trial, we divided eighty participants into three groups: one engaged in green exercise (mountain hiking), another combined hiking with magnesium-calcium-sulfate thermal baths, and a control group received no treatment.

Our findings showed significant improvements in back pain among participants who participated in hiking and bathing in thermal water compared to those who didn't receive any intervention. However, it is important to note that we cannot isolate the benefits of magnesium treatment since it was combined with the physical activity of hiking. Therefore, while magnesium's involvement is notable, its individual impact remains unclear from our results.

This study highlights the promise of integrating physical activities like mountain hiking alongside therapeutic treatments for managing chronic back pain. Future research should delve deeper into the long-term effects of such multi-faceted therapies to fully understand the role of magnesium in this context.
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User Reviews

USERS' SCORE
Good
Based on 1 Review
8.5
8.8
Lowered arthritic pain
My blood pressure is back to normal after starting this supplement, and I have also experienced reduced arthritic pain in my hips, knees, and back.
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