Overview
SCIENTIFIC SCORE
Questionable
Based on 20 Researches
6.8
USERS' SCORE
Good
Based on 13 Reviews
8.1
Supplement Facts
Serving Size: 2 Veg Capsules
Amount Per Serving
%DV
Magnesium (from Magnesium Aspartate)
250 mg
60%
Potassium (from Potassium Aspartate)
99 mg
2%
Taurine (Free-Form)
100 mg
†
Top Medical Research Studies
8
We explored the potential connection between dietary potassium intake and the occurrence of severe headaches or migraines. Utilizing data from over 10,000 US adults gathered through a national health survey from 1999 to 2004, we conducted a thorough analysis.
While we found that higher potassium intake was linked to a lower likelihood of migraines, the relationship appeared to be L-shaped, suggesting that there might be an optimal level of intake rather than a straightforward benefit. There's no strong evidence that potassium dramatically decreases headache frequency, but it does seem to play a role worth noting.
While we found that higher potassium intake was linked to a lower likelihood of migraines, the relationship appeared to be L-shaped, suggesting that there might be an optimal level of intake rather than a straightforward benefit. There's no strong evidence that potassium dramatically decreases headache frequency, but it does seem to play a role worth noting.
Read More
9.5
Potassium channel influence on migraines
We assessed whether levcromakalim, a potassium channel opener, influences migraine attacks in individuals already treated with erenumab. Conducted as a double-blind, placebo-controlled trial, our findings show that a significant number of participants reported migraines after receiving levcromakalim compared to placebo.
Specifically, 88% experienced migraine attacks following levcromakalim, vs. just 12% after the placebo. The study suggests that potassium channel activation may trigger migraine attacks independently of certain receptors typically associated with migraines.
Specifically, 88% experienced migraine attacks following levcromakalim, vs. just 12% after the placebo. The study suggests that potassium channel activation may trigger migraine attacks independently of certain receptors typically associated with migraines.
Read More
9
Magnesium aids migraine management
We explored the impact of magnesium on migraine headaches, focusing on its potential benefits based on various studies. Magnesium deficiency is quite common and can arise from different factors, such as not consuming enough through diet or losing more through bodily systems.
A wealth of research, including case reports and controlled trials, suggests that magnesium supplementation can effectively alleviate migraines, both in the short term and long term. The proposed reasons for this effectiveness range from magnesium's role in preventing spreading cortical depression to its ability to manage oxidative stress and inflammation.
This evidence leads us to consider magnesium not just as a dietary supplement but as an important player in migraine management. Understanding these links helps us contemplate magnesium’s role in prevention and treatment, promising a potential path for those who suffer from this debilitating condition.
A wealth of research, including case reports and controlled trials, suggests that magnesium supplementation can effectively alleviate migraines, both in the short term and long term. The proposed reasons for this effectiveness range from magnesium's role in preventing spreading cortical depression to its ability to manage oxidative stress and inflammation.
This evidence leads us to consider magnesium not just as a dietary supplement but as an important player in migraine management. Understanding these links helps us contemplate magnesium’s role in prevention and treatment, promising a potential path for those who suffer from this debilitating condition.
Read More
Most Useful Reviews
10
No migraines
4 people found this helpful
I haven't had any headaches for three weeks since I began taking two capsules twice a day. I have not required any pharmaceutical drugs to manage my migraines, which is fantastic!
Read More
9
Headache helper
This magnesium supplement has been very helpful for my headaches.
Read More
9
Effective for headaches
I have been taking magnesium for over 20 years. It aids restful sleep, alleviates headaches, and helps remove calcifications. I often switch brands and types of magnesium.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 20 Researches
6.8
- All Researches
9.5
Potassium channel influence on migraines
We assessed whether levcromakalim, a potassium channel opener, influences migraine attacks in individuals already treated with erenumab. Conducted as a double-blind, placebo-controlled trial, our findings show that a significant number of participants reported migraines after receiving levcromakalim compared to placebo.
Specifically, 88% experienced migraine attacks following levcromakalim, vs. just 12% after the placebo. The study suggests that potassium channel activation may trigger migraine attacks independently of certain receptors typically associated with migraines.
Specifically, 88% experienced migraine attacks following levcromakalim, vs. just 12% after the placebo. The study suggests that potassium channel activation may trigger migraine attacks independently of certain receptors typically associated with migraines.
Read More
9
Magnesium aids migraine management
We explored the impact of magnesium on migraine headaches, focusing on its potential benefits based on various studies. Magnesium deficiency is quite common and can arise from different factors, such as not consuming enough through diet or losing more through bodily systems.
A wealth of research, including case reports and controlled trials, suggests that magnesium supplementation can effectively alleviate migraines, both in the short term and long term. The proposed reasons for this effectiveness range from magnesium's role in preventing spreading cortical depression to its ability to manage oxidative stress and inflammation.
This evidence leads us to consider magnesium not just as a dietary supplement but as an important player in migraine management. Understanding these links helps us contemplate magnesium’s role in prevention and treatment, promising a potential path for those who suffer from this debilitating condition.
A wealth of research, including case reports and controlled trials, suggests that magnesium supplementation can effectively alleviate migraines, both in the short term and long term. The proposed reasons for this effectiveness range from magnesium's role in preventing spreading cortical depression to its ability to manage oxidative stress and inflammation.
This evidence leads us to consider magnesium not just as a dietary supplement but as an important player in migraine management. Understanding these links helps us contemplate magnesium’s role in prevention and treatment, promising a potential path for those who suffer from this debilitating condition.
Read More
9
We examined the effects of magnesium treatment on individuals suffering from episodic migraine and tension-type headache, aiming to understand its potential benefits alongside other therapeutic approaches. The study involved 104 participants, who were assessed for anxiety, depression, insomnia, and fatigue before and after receiving various treatments, including magnesium.
Our findings indicated that a significant portion of patients reported anxiety and depression, affecting their headache severity. After treatment, we noticed a marked decrease in headache intensity, along with improvements in anxiety and depressive symptoms. However, the specific impact of magnesium alone couldn’t be isolated in this study, as we looked at it alongside other medications like anxiolytics and antidepressants.
Overall, while magnesium was part of the treatment plan and showed potential benefits, we must acknowledge that its individual effectiveness cannot be clearly determined from our research. It appears to contribute to an overall improvement in managing headaches when combined with other treatments.
Our findings indicated that a significant portion of patients reported anxiety and depression, affecting their headache severity. After treatment, we noticed a marked decrease in headache intensity, along with improvements in anxiety and depressive symptoms. However, the specific impact of magnesium alone couldn’t be isolated in this study, as we looked at it alongside other medications like anxiolytics and antidepressants.
Overall, while magnesium was part of the treatment plan and showed potential benefits, we must acknowledge that its individual effectiveness cannot be clearly determined from our research. It appears to contribute to an overall improvement in managing headaches when combined with other treatments.
Read More
9
We explored a case involving a 36-year-old woman with endometriosis suffering from frequent headaches and debilitating pain. While traditional medications didn't work for her, she started a new treatment plan that included acupuncture and supplements like magnesium and turmeric.
After this multimodal approach, her headache frequency decreased significantly, along with improvements in her lumbopelvic pain, sleep quality, and overall focus. This case indicates that integrating various alternative therapies can provide significant relief for those with challenging symptoms.
After this multimodal approach, her headache frequency decreased significantly, along with improvements in her lumbopelvic pain, sleep quality, and overall focus. This case indicates that integrating various alternative therapies can provide significant relief for those with challenging symptoms.
Read More
8
We conducted a study assessing how nonprescription therapies, particularly a combination product containing magnesium, affect symptoms of vestibular migraine (VM). Our research involved collecting data from patients diagnosed with VM who were given guidance on lifestyle changes, like hydration and nutrition, alongside the supplement.
After three months of treatment, we observed promising results. The severity and frequency of headache-related symptoms showed significant improvement based on assessments using established scales. For instance, participants reported a reduction in dizziness and headache intensity, with many noting a better quality of life.
Notably, half of the patients observed an enhancement in their symptoms, while most tolerated the supplement without any issues. These findings suggest that magnesium, when combined with other nutrients, could contribute positively to managing VM headaches.
Overall, our study offers preliminary support for magnesium's potential role in treating VM, particularly through a holistic approach that includes lifestyle modifications.
After three months of treatment, we observed promising results. The severity and frequency of headache-related symptoms showed significant improvement based on assessments using established scales. For instance, participants reported a reduction in dizziness and headache intensity, with many noting a better quality of life.
Notably, half of the patients observed an enhancement in their symptoms, while most tolerated the supplement without any issues. These findings suggest that magnesium, when combined with other nutrients, could contribute positively to managing VM headaches.
Overall, our study offers preliminary support for magnesium's potential role in treating VM, particularly through a holistic approach that includes lifestyle modifications.
Read More
User Reviews
USERS' SCORE
Good
Based on 13 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
10
No migraines
4 people found this helpful
I haven't had any headaches for three weeks since I began taking two capsules twice a day. I have not required any pharmaceutical drugs to manage my migraines, which is fantastic!
Read More
9
Headache helper
This magnesium supplement has been very helpful for my headaches.
Read More
9
Effective for headaches
I have been taking magnesium for over 20 years. It aids restful sleep, alleviates headaches, and helps remove calcifications. I often switch brands and types of magnesium.
Read More
7.5
Reduced headaches
13 people found this helpful
Excellent! I follow the keto diet, and I've noticed a significant improvement in my condition. My headaches, dizziness, muscle pain, and sleep have become much more manageable, although I do find myself needing to visit the bathroom frequently.
Read More
7.5
Improved sleep quality
6 people found this helpful
Life changer! My boyfriend began taking these supplements for his headaches, and people mentioned benefits for TMJ and insomnia, which I also suffer from. Since I started, my sleep quality has improved and my TMJ issues have significantly lessened. I previously experienced considerable pain and muscle spasms, but now they last only a day and are much less intense.
Read More
Frequently Asked Questions
10
No migraines
4 people found this helpful
I haven't had any headaches for three weeks since I began taking two capsules twice a day. I have not required any pharmaceutical drugs to manage my migraines, which is fantastic!
9
Headache helper
This magnesium supplement has been very helpful for my headaches.
7.5
Neck pain relief
3 people found this helpful
After taking a couple of these capsules, my stiff neck has become much more relaxed. With regular use, I rarely experience tension headaches. This supplement is truly life-changing.
9
Effective for headaches
I have been taking magnesium for over 20 years. It aids restful sleep, alleviates headaches, and helps remove calcifications. I often switch brands and types of magnesium.
7.5
Reduced headaches
13 people found this helpful
Excellent! I follow the keto diet, and I've noticed a significant improvement in my condition. My headaches, dizziness, muscle pain, and sleep have become much more manageable, although I do find myself needing to visit the bathroom frequently.
9
No headaches reported
Good. My husband has high blood pressure and migraines and hasn't complained of a headache since he started taking the supplement.
9
Magnesium aids migraine management
We explored the impact of magnesium on migraine headaches, focusing on its potential benefits based on various studies. Magnesium deficiency is quite common and can arise from different factors, such as not consuming enough through diet or losing more through bodily systems.
A wealth of research, including case reports and controlled trials, suggests that magnesium supplementation can effectively alleviate migraines, both in the short term and long term. The proposed reasons for this effectiveness range from magnesium's role in preventing spreading cortical depression to its ability to manage oxidative stress and inflammation.
This evidence leads us to consider magnesium not just as a dietary supplement but as an important player in migraine management. Understanding these links helps us contemplate magnesium’s role in prevention and treatment, promising a potential path for those who suffer from this debilitating condition.
A wealth of research, including case reports and controlled trials, suggests that magnesium supplementation can effectively alleviate migraines, both in the short term and long term. The proposed reasons for this effectiveness range from magnesium's role in preventing spreading cortical depression to its ability to manage oxidative stress and inflammation.
This evidence leads us to consider magnesium not just as a dietary supplement but as an important player in migraine management. Understanding these links helps us contemplate magnesium’s role in prevention and treatment, promising a potential path for those who suffer from this debilitating condition.
7
We explored the impact of magnesium treatment on headaches, focusing specifically on its role in preventing migraines. The evidence suggests that magnesium may be beneficial for some individuals in managing headache frequency and intensity. It is often recommended not only for migraine prevention but also for acute treatment when given intravenously.
Importantly, we noted that magnesium tends to have a good safety profile, with any adverse effects typically being mild and related to gastrointestinal tolerance. This makes it a potentially attractive option for those seeking relief from headaches. However, it's crucial to approach magnesium use with careful consideration, recognizing that responses can vary from person to person.
Overall, our examination highlights magnesium as a valuable tool in the headache management arsenal, although it should be part of a more comprehensive treatment strategy. Knowing its benefits allows us to better inform those struggling with headache disorders.
Importantly, we noted that magnesium tends to have a good safety profile, with any adverse effects typically being mild and related to gastrointestinal tolerance. This makes it a potentially attractive option for those seeking relief from headaches. However, it's crucial to approach magnesium use with careful consideration, recognizing that responses can vary from person to person.
Overall, our examination highlights magnesium as a valuable tool in the headache management arsenal, although it should be part of a more comprehensive treatment strategy. Knowing its benefits allows us to better inform those struggling with headache disorders.
9
We examined the effects of magnesium treatment on individuals suffering from episodic migraine and tension-type headache, aiming to understand its potential benefits alongside other therapeutic approaches. The study involved 104 participants, who were assessed for anxiety, depression, insomnia, and fatigue before and after receiving various treatments, including magnesium.
Our findings indicated that a significant portion of patients reported anxiety and depression, affecting their headache severity. After treatment, we noticed a marked decrease in headache intensity, along with improvements in anxiety and depressive symptoms. However, the specific impact of magnesium alone couldn’t be isolated in this study, as we looked at it alongside other medications like anxiolytics and antidepressants.
Overall, while magnesium was part of the treatment plan and showed potential benefits, we must acknowledge that its individual effectiveness cannot be clearly determined from our research. It appears to contribute to an overall improvement in managing headaches when combined with other treatments.
Our findings indicated that a significant portion of patients reported anxiety and depression, affecting their headache severity. After treatment, we noticed a marked decrease in headache intensity, along with improvements in anxiety and depressive symptoms. However, the specific impact of magnesium alone couldn’t be isolated in this study, as we looked at it alongside other medications like anxiolytics and antidepressants.
Overall, while magnesium was part of the treatment plan and showed potential benefits, we must acknowledge that its individual effectiveness cannot be clearly determined from our research. It appears to contribute to an overall improvement in managing headaches when combined with other treatments.
References
- Dominguez LJ, Veronese N, Sabico S, Al-Daghri NM, Barbagallo M. Magnesium and Migraine. Nutrients. 2025;17. doi:10.3390/nu17040725
- Tepper SJ, Tepper K. Nutraceuticals and Headache 2024: Riboflavin, Coenzyme Q10, Feverfew, Magnesium, Melatonin, and Butterbur. Curr Pain Headache Rep. 2025;29:33. doi:10.1007/s11916-025-01358-3
- Hannigan IP, Rosengren SM, Di Tanna GL, Watson SRD, Welgampola MS. Effects of nonprescription therapies on vestibular migraine: a questionnaire-based observational study. Intern Med J. 2024;54:916. doi:10.1111/imj.16314
- Mirzaeva LM, Lobzina AS, Akhmedova KN, Shvartsman GI, Kula II, et al. [Therapeutic approaches to comorbid pathology in episodic migraine and tension-type headache]. Zh Nevrol Psikhiatr Im S S Korsakova. 2023;123:52. doi:10.17116/jnevro202312309152
- Gaul C, Zaranek L, Goßrau G. [Complementary and supplementary procedures in the treatment of headache]. Schmerz. 2023;37:448. doi:10.1007/s00482-023-00738-1
- Frank M, Abouzari M, Djalilian HR. Meniere's disease is a manifestation of migraine. Curr Opin Otolaryngol Head Neck Surg. 2023;31:313. doi:10.1097/MOO.0000000000000908
- Verhaak A, Bakaysa S, Johnson A, Veronesi M, Williamson A, et al. Migraine treatment in pregnancy: A survey of comfort and treatment practices of women's healthcare providers. Headache. 2023;63:211. doi:10.1111/head.14436
- Mahajan R, Anand KS, Mahajan RK, Garg J, Juneja A. Serum Magnesium Levels During the Ictal and Interictal Phase in Patients of Migraine: A Prospective Observational Study. Neurol India. 2022;70:1852. doi:10.4103/0028-3886.359247
- Wilson A, Hodgetts-Morton VA, Marson EJ, Markland AD, Larkai E, et al. Tocolytics for delaying preterm birth: a network meta-analysis (0924). Cochrane Database Syst Rev. 2022;8:CD014978. doi:10.1002/14651858.CD014978.pub2
- Bhurat R, Premkumar S, Manokaran RK. Serum Magnesium Levels in Children With and Without Migraine: A Cross-Sectional Study. Indian Pediatr. 2022;59:623.
- Bharadwaj VN, Meyerowitz J, Zou B, Klukinov M, Yan N, et al. Impact of Magnesium on Oxytocin Receptor Function. Pharmaceutics. 2022;14. doi:10.3390/pharmaceutics14051105
- Martin BR. Multimodal Care for Headaches, Lumbopelvic Pain, and Dysmenorrhea in a Woman With Endometriosis: A Case Report. J Chiropr Med. 2021;20:148. doi:10.1016/j.jcm.2021.10.002
- Al-Khazali HM, Christensen RH, Dodick DW, Chaudhry BA, Melchior AG, et al. Hypersensitivity to BK channel opening in persistent post-traumatic headache. J Headache Pain. 2024;25:102. doi:10.1186/s10194-024-01808-0
- Kokoti L, Al-Karagholi MA, Zhuang ZA, Amirguliyev S, Amin FM, et al. Non-vascular ATP-sensitive potassium channel activation does not trigger migraine attacks: A randomized clinical trial. Cephalalgia. 2024;44:3331024241248211. doi:10.1177/03331024241248211
- Haghdoost F, Gnanenthiran SR, Shan S, Kaistha P, Huang L, et al. The effect of salt substitution on frequency and severity of headache: results from the SSaSS cluster-randomised controlled trial of 20,995 participants. Eur J Clin Nutr. 2024;78:401. doi:10.1038/s41430-024-01419-7
- Raffaelli B, Do TP, Chaudhry BA, Amin FM, Ashina H, et al. Activation of ATP-sensitive potassium channels triggers migraine attacks independent of calcitonin gene-related peptide receptors: a randomized placebo-controlled trial. Cephalalgia. 2024;44:3331024231222916. doi:10.1177/03331024231222916
- Al-Khazali HM, Deligianni CI, Pellesi L, Al-Karagholi MA, Ashina H, et al. Induction of cluster headache after opening of adenosine triphosphate-sensitive potassium channels: a randomized clinical trial. Pain. 2024;165:1289. doi:10.1097/j.pain.0000000000003130
- Al-Khazali HM, Christensen RH, Dodick DW, Chaudhry BA, Burstein R, et al. Hypersensitivity to opening of ATP-sensitive potassium channels in post-traumatic headache. Cephalalgia. 2023;43:3331024231210930. doi:10.1177/03331024231210930
- Xu L, Zhang C, Liu Y, Shang X, Huang D. Association between dietary potassium intake and severe headache or migraine in US adults: a population-based analysis. Front Nutr. 2023;10:1255468. doi:10.3389/fnut.2023.1255468
- Ferreira SE, de Mello MT, Pompéia S, de Souza-Formigoni ML. Effects of energy drink ingestion on alcohol intoxication. Alcohol Clin Exp Res. 2006;30:598.
