Last update
5/13/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Good
Based on 4 Reviews
8.2
Supplement Facts
Serving Size: 2 Veg Capsules
Amount Per Serving
%DV
Magnesium (from Magnesium Aspartate)
250 mg
60%
Potassium (from Potassium Aspartate)
99 mg
2%
Taurine (Free-Form)
100 mg
†
Top Medical Research Studies
8
We set out to understand how magnesium sulphate influences the symptoms of irritable bowel syndrome (IBS). In a study involving 20 IBS patients, magnesium sulphate was administered orally, resulting in a quick boost in colonic motor activity. Most participants experienced this increase within just two to six minutes.
Specifically, the percentage of colonic activity rose from 16.2% to 23.7%, signaling a notable change. Those who often felt abdominal pain after eating showed even more pronounced reactions, with their activity jumping from 16.1% to 29.8%. However, it’s important to note that three of these patients still experienced their usual pain after taking magnesium, suggesting that while magnesium can enhance motility, it doesn’t eliminate the pain for everyone.
Ultimately, these findings lend support to the idea that some cases of abdominal pain related to food may stem from heightened intestinal responses to cholecystokinin, a hormone released by the intestine. So while magnesium shows promise for intriguing changes in colonic movement in IBS patients, its effectiveness in alleviating pain remains mixed.
Specifically, the percentage of colonic activity rose from 16.2% to 23.7%, signaling a notable change. Those who often felt abdominal pain after eating showed even more pronounced reactions, with their activity jumping from 16.1% to 29.8%. However, it’s important to note that three of these patients still experienced their usual pain after taking magnesium, suggesting that while magnesium can enhance motility, it doesn’t eliminate the pain for everyone.
Ultimately, these findings lend support to the idea that some cases of abdominal pain related to food may stem from heightened intestinal responses to cholecystokinin, a hormone released by the intestine. So while magnesium shows promise for intriguing changes in colonic movement in IBS patients, its effectiveness in alleviating pain remains mixed.
Read More
8
Bile acid sequestrant A3384 shows promise
We investigated how a novel colonic-release formulation of colestyramine, A3384, impacts bile acid metabolism and bowel function in patients with primary bile acid diarrhoea (BAD).
In a double-blind study, participants received either A3384 or a placebo for two weeks. While conventional bile acid sequestrants lowered serum fibroblast growth factor 19 (FGF19) and increased bile acid production, A3384 did not exhibit this effect.
However, A3384 did improve diarrhoeal symptoms, showing promise as a better-tolerated treatment option for BAD.
In a double-blind study, participants received either A3384 or a placebo for two weeks. While conventional bile acid sequestrants lowered serum fibroblast growth factor 19 (FGF19) and increased bile acid production, A3384 did not exhibit this effect.
However, A3384 did improve diarrhoeal symptoms, showing promise as a better-tolerated treatment option for BAD.
Read More
Most Useful Reviews
9
Improved mood
After a week of taking 1500mg daily, my sleep improved significantly, and my bowel issues were resolved. I felt less irritable and more productive mentally, proving that this supplement works effectively.
Read More
7.5
Improved bowel function
I have noticed a significant improvement in sleep and my bowel function since taking magnesium and potassium. After a week, I fell asleep faster and felt more rested in the morning. I became less irritable and more productive. It helps with my irritable bowel syndrome as well. I take 2 capsules daily, and I would recommend this to anyone looking to enhance their well-being naturally. If my review was helpful, please click Yes. Thank you!
Read More
7.5
Quick effects
I take it regularly; when I feel irritable, I take it for a week. It greatly assists with my symptoms of irritable bowel syndrome, alleviating cramps within two days.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
- All Researches
8
We set out to understand how magnesium sulphate influences the symptoms of irritable bowel syndrome (IBS). In a study involving 20 IBS patients, magnesium sulphate was administered orally, resulting in a quick boost in colonic motor activity. Most participants experienced this increase within just two to six minutes.
Specifically, the percentage of colonic activity rose from 16.2% to 23.7%, signaling a notable change. Those who often felt abdominal pain after eating showed even more pronounced reactions, with their activity jumping from 16.1% to 29.8%. However, it’s important to note that three of these patients still experienced their usual pain after taking magnesium, suggesting that while magnesium can enhance motility, it doesn’t eliminate the pain for everyone.
Ultimately, these findings lend support to the idea that some cases of abdominal pain related to food may stem from heightened intestinal responses to cholecystokinin, a hormone released by the intestine. So while magnesium shows promise for intriguing changes in colonic movement in IBS patients, its effectiveness in alleviating pain remains mixed.
Specifically, the percentage of colonic activity rose from 16.2% to 23.7%, signaling a notable change. Those who often felt abdominal pain after eating showed even more pronounced reactions, with their activity jumping from 16.1% to 29.8%. However, it’s important to note that three of these patients still experienced their usual pain after taking magnesium, suggesting that while magnesium can enhance motility, it doesn’t eliminate the pain for everyone.
Ultimately, these findings lend support to the idea that some cases of abdominal pain related to food may stem from heightened intestinal responses to cholecystokinin, a hormone released by the intestine. So while magnesium shows promise for intriguing changes in colonic movement in IBS patients, its effectiveness in alleviating pain remains mixed.
Read More
8
Bile acid sequestrant A3384 shows promise
We investigated how a novel colonic-release formulation of colestyramine, A3384, impacts bile acid metabolism and bowel function in patients with primary bile acid diarrhoea (BAD).
In a double-blind study, participants received either A3384 or a placebo for two weeks. While conventional bile acid sequestrants lowered serum fibroblast growth factor 19 (FGF19) and increased bile acid production, A3384 did not exhibit this effect.
However, A3384 did improve diarrhoeal symptoms, showing promise as a better-tolerated treatment option for BAD.
In a double-blind study, participants received either A3384 or a placebo for two weeks. While conventional bile acid sequestrants lowered serum fibroblast growth factor 19 (FGF19) and increased bile acid production, A3384 did not exhibit this effect.
However, A3384 did improve diarrhoeal symptoms, showing promise as a better-tolerated treatment option for BAD.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
Improved mood
After a week of taking 1500mg daily, my sleep improved significantly, and my bowel issues were resolved. I felt less irritable and more productive mentally, proving that this supplement works effectively.
Read More
7.5
Improved bowel function
I have noticed a significant improvement in sleep and my bowel function since taking magnesium and potassium. After a week, I fell asleep faster and felt more rested in the morning. I became less irritable and more productive. It helps with my irritable bowel syndrome as well. I take 2 capsules daily, and I would recommend this to anyone looking to enhance their well-being naturally. If my review was helpful, please click Yes. Thank you!
Read More
7.5
Quick effects
I take it regularly; when I feel irritable, I take it for a week. It greatly assists with my symptoms of irritable bowel syndrome, alleviating cramps within two days.
Read More
6
Loose stools warning
1 people found this helpful
Taking one capsule is fine for my family, but two caused loose bowel symptoms.
Read More
Frequently Asked Questions
9
Improved mood
After a week of taking 1500mg daily, my sleep improved significantly, and my bowel issues were resolved. I felt less irritable and more productive mentally, proving that this supplement works effectively.
7.5
Quick effects
I take it regularly; when I feel irritable, I take it for a week. It greatly assists with my symptoms of irritable bowel syndrome, alleviating cramps within two days.
6
Loose stools warning
1 people found this helpful
Taking one capsule is fine for my family, but two caused loose bowel symptoms.
8
We set out to understand how magnesium sulphate influences the symptoms of irritable bowel syndrome (IBS). In a study involving 20 IBS patients, magnesium sulphate was administered orally, resulting in a quick boost in colonic motor activity. Most participants experienced this increase within just two to six minutes.
Specifically, the percentage of colonic activity rose from 16.2% to 23.7%, signaling a notable change. Those who often felt abdominal pain after eating showed even more pronounced reactions, with their activity jumping from 16.1% to 29.8%. However, it’s important to note that three of these patients still experienced their usual pain after taking magnesium, suggesting that while magnesium can enhance motility, it doesn’t eliminate the pain for everyone.
Ultimately, these findings lend support to the idea that some cases of abdominal pain related to food may stem from heightened intestinal responses to cholecystokinin, a hormone released by the intestine. So while magnesium shows promise for intriguing changes in colonic movement in IBS patients, its effectiveness in alleviating pain remains mixed.
Specifically, the percentage of colonic activity rose from 16.2% to 23.7%, signaling a notable change. Those who often felt abdominal pain after eating showed even more pronounced reactions, with their activity jumping from 16.1% to 29.8%. However, it’s important to note that three of these patients still experienced their usual pain after taking magnesium, suggesting that while magnesium can enhance motility, it doesn’t eliminate the pain for everyone.
Ultimately, these findings lend support to the idea that some cases of abdominal pain related to food may stem from heightened intestinal responses to cholecystokinin, a hormone released by the intestine. So while magnesium shows promise for intriguing changes in colonic movement in IBS patients, its effectiveness in alleviating pain remains mixed.
8
Bile acid sequestrant A3384 shows promise
We investigated how a novel colonic-release formulation of colestyramine, A3384, impacts bile acid metabolism and bowel function in patients with primary bile acid diarrhoea (BAD).
In a double-blind study, participants received either A3384 or a placebo for two weeks. While conventional bile acid sequestrants lowered serum fibroblast growth factor 19 (FGF19) and increased bile acid production, A3384 did not exhibit this effect.
However, A3384 did improve diarrhoeal symptoms, showing promise as a better-tolerated treatment option for BAD.
In a double-blind study, participants received either A3384 or a placebo for two weeks. While conventional bile acid sequestrants lowered serum fibroblast growth factor 19 (FGF19) and increased bile acid production, A3384 did not exhibit this effect.
However, A3384 did improve diarrhoeal symptoms, showing promise as a better-tolerated treatment option for BAD.
References
- Harvey RF, Read AE. Effects of oral magnesium sulphate on colonic motility in patients with the irritable bowel syndrome. Gut. 1973;14:983. PubMed
- Appleby RN, Bajor A, Gillberg PG, Graffner H, Simrén M, et al. Effects of conventional and a novel colonic-release bile acid sequestrant, A3384, on fibroblast growth factor 19 and bile acid metabolism in healthy volunteers and patients with bile acid diarrhoea. United European Gastroenterol J. 2017;5:380. 10.1177/2050640616662432
