We investigated whether adding eicosapentaenoic acid (EPA), an omega-3 fatty acid, to statin therapy could help reduce chest pain linked to coronary heart disease. In this randomized controlled trial involving 193 patients, those taking both EPA and pitavastatin experienced a significant reduction in coronary plaque volume compared to those on statins alone.
While the combination therapy particularly benefited patients with stable angina, it did not reduce major cardiovascular events or side effects. This suggests that while EPA may enhance plaque stability, it does not necessarily lower chest pain symptoms in all cases.
Read More
Fish oil reduces cardiac eventsRandomized, double-blind, placebo-controlled trial of fish oil and mustard oil in patients with suspected acute myocardial infarction: the Indian experiment of infarct survival--4.
High relevance in heart health
We examined the effects of fish oil on chest pain in a randomized trial involving 360 patients experiencing suspected acute myocardial infarction.
After one year, we found that those taking fish oil had significantly fewer cardiac events and nonfatal infarctions compared to the placebo group.
Interestingly, while fish oil appeared to lower cardiac death rates, mustard oil showed no similar benefit.
Overall, this suggests that fish oil may offer protective effects, though more extensive research is needed for confirmation.
Read More
Low-dose fish oil aids anginaEffects of a low-dose fish oil concentrate on angina, exercise tolerance time, serum triglycerides, and platelet function.
Highly valuable clinical insights
We explored the effects of low-dose fish oil concentrate on patients experiencing angina due to coronary artery disease. In a study with 39 patients, one group received fish oil while the other was given a placebo.
Remarkably, we observed that the fish oil group experienced a 41% reduction in anginal attacks and a significant decrease in medication use over the treatment period. They also enjoyed longer exercise tolerance times and lower serum triglycerides.
Conversely, the placebo group showed no significant changes. Our findings suggest that low-dose fish oil may indeed benefit those struggling with chest pain.
Read More
Promising effects of fish oilPilot trial to determine the efficacy of a low dose of fish oil in the treatment of angina pectoris in the geriatric patient.
High relevance for elderly care
We conducted a trial involving 23 geriatric patients to see if low-dose fish oil could help with angina pectoris.
Using a single-blind, placebo-controlled, crossover design, we discovered that fish oil significantly reduced the number of anginal attacks and the need for sublingual isosorbide dinitrate tablets.
Additionally, there seemed to be a lingering effect of fish oil even after switching to the placebo, suggesting potential long-term benefits.
Read More
Omega-3 reduces angina symptomsThe long-term effect of dietary supplementation with fish lipid concentrate on serum lipids, bleeding time, platelets and angina.
Relevant to heart health improvement
We examined the long-term effects of a fish lipid concentrate high in eicosapentaenoic acid in 107 subjects, some with heart conditions and others without. Over two years, we noticed marked reductions in triglycerides, a mild decrease in total cholesterol, and an increase in HDL cholesterol.
Notably, we found a significant decrease in the use of GTN tablets, correlating with fewer angina attacks. This suggests that omega-3 may help enhance heart health by reducing symptoms and improving lipid profiles, although bleeding times also increased.
Read More