We embarked on a study to find out how dietary eicosapentaenoic acid (EPA) could help children suffering from atopic dermatitis, a common form of eczema. In a randomized triple-blind clinical trial, 48 children with this condition were divided into two groups—one received 250 mg of EPA twice daily, while the other received a placebo for four weeks.
Our observations showed noticeable improvements in those who took EPA. After just two weeks, participants in the EPA group reported a reduction in their SCORAD scores, which are used to measure the severity of atopic dermatitis. The scores went down significantly compared to the placebo group. After four weeks, the number of children needing corticosteroids to manage their symptoms was also lower in the EPA group.
Despite these positive results, both groups reported few adverse effects, indicating that EPA supplementation is generally well-received. Overall, we conclude that adding EPA to the diet may be an effective and safe strategy for reducing eczema severity in children.
Read More
8
DHA shows promise for eczema
Docosahexaenoic acid (DHA) supplementation in atopic eczema: a randomized, double-blind, controlled trial.
In a controlled trial, we assessed how docosahexaenoic acid (DHA)—an omega-3 fatty acid—affects atopic eczema. Fifty-three patients, aged 18 to 40, were randomly assigned to receive either 5.4 grams of DHA daily or an isoenergetic control comprising saturated fatty acids for eight weeks. This double-blind setup helped ensure that neither the participants nor the researchers knew who received which treatment, thereby reducing bias in the results.
Throughout the study, we measured the severity of eczema using the SCORAD index at multiple intervals. Our findings showed that DHA supplementation led to a notable improvement in eczema symptoms, with patients experiencing a significant decrease in their SCORAD scores. This contrasted with the control group, which did not show similar improvements. Notably, we also found that DHA reduced certain immune responses linked to eczema, indicating its potential role in managing this condition.
Given these encouraging results, it appears that DHA could be an effective dietary addition for people suffering from atopic eczema. However, further research with a larger participant pool is necessary to confirm these findings and fully understand the benefits of DHA on this skin condition.
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8
DHA linked to lower eczema
Relationship between dietary fat and fish intake and the prevalence of atopic eczema in pregnant Japanese females: baseline data from the Osaka Maternal and Child Health Study.
We examined how dietary factors, particularly docosahexaenoic acid (DHA), influence the prevalence of atopic eczema among pregnant Japanese females. In a study involving 1,002 participants, we gathered data through a detailed diet history questionnaire, focusing on their intake of various fatty acids and the occurrence of atopic eczema.
Our findings revealed that DHA intake was significantly linked to a reduced rate of atopic eczema both currently and after the age of 18. However, we did not find consistent evidence supporting the idea that n-3 and n-6 polyunsaturated fatty acids, as well as total fat and other types of dietary fat, had a meaningful effect on eczema.
While the study encourages the inclusion of DHA in the diet during pregnancy, it also highlights the complexity of dietary impacts on allergic conditions like eczema. Overall, we observed a noteworthy association between higher DHA intake and lower prevalence rates of eczema in this group, suggesting that it could be a beneficial addition to the diets of pregnant women.
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Most Useful Reviews
7.5
Eczema management
19 people found this helpful
My skin is fragile due to weak intestines, leading to issues like acne and eczema. Combining it with NOW Vitamin C and pantothenic acid has helped significantly since I began taking it. Previously, I struggled with eczema around my hands, which has improved notably. I appreciate Omega-3 and consider it essential for my well-being, especially in managing eczema.
Read More
9
Soothes eczema
2 people found this helpful
Works perfectly for me, though I’m saddened that they no longer ship to Spain. I’ve taken it for years, and it effectively lowers inflammation and soothes my eczema.
Read More
9
Skin improvement
I bought fish oil for my husband, who has dry skin and eczema. After two weeks, his skin showed noticeable improvement!
We embarked on a study to find out how dietary eicosapentaenoic acid (EPA) could help children suffering from atopic dermatitis, a common form of eczema. In a randomized triple-blind clinical trial, 48 children with this condition were divided into two groups—one received 250 mg of EPA twice daily, while the other received a placebo for four weeks.
Our observations showed noticeable improvements in those who took EPA. After just two weeks, participants in the EPA group reported a reduction in their SCORAD scores, which are used to measure the severity of atopic dermatitis. The scores went down significantly compared to the placebo group. After four weeks, the number of children needing corticosteroids to manage their symptoms was also lower in the EPA group.
Despite these positive results, both groups reported few adverse effects, indicating that EPA supplementation is generally well-received. Overall, we conclude that adding EPA to the diet may be an effective and safe strategy for reducing eczema severity in children.
Read More
8
Maternal PUFA linked to reduced allergies
Association of Maternal Erythrocyte PUFA during Pregnancy with Offspring Allergy in the Chinese Population.
We examined the relationship between maternal polyunsaturated fatty acids (PUFA) during pregnancy and the risk of allergies, including eczema, in their children within the first two years of life.
In our study with 573 mother-infant pairs, we found that higher levels of certain fatty acids, especially arachidonic acid and omega-3 PUFA, were associated with a reduced risk of allergies in children.
This trend was notably stronger for children whose mothers had a history of allergies. Overall, our research suggests that maternal PUFA intake might play a protective role against eczema and other allergic conditions.
Read More
8
EPA-E improves eczema-like symptoms
Eicosapentaenoic acid ethyl ester ameliorates atopic dermatitis-like symptoms in special diet-fed hairless mice, partly by restoring covalently bound ceramides in the stratum corneum.
We explored how eicosapentaenoic acid ethyl ester (EPA-E), a component of omega-3 fish oil, affects atopic dermatitis-like symptoms in mice. This study showed that EPA-E could improve skin barrier issues and reduce itching in mice with conditions similar to human eczema.
We observed that the treatment helped restore important lipids in the skin, known as ceramides. These results suggest that EPA-E may offer a promising approach to treat eczema in people, but further testing is needed.
Read More
8
Fish consumption and allergic outcomes
Fish intake during pregnancy or infancy and allergic outcomes in children: A systematic review and meta-analysis.
We investigated how fish consumption during pregnancy and infancy influences allergic conditions in children. Our analysis included a range of studies, revealing that while mothers eating fish during pregnancy didn't seem to lower allergy risks, infants consuming fish in their first year notably reduced eczema occurrences.
Specifically, we found a reduced risk of eczema and allergic rhinitis in those who consumed fish early in life. This indicates that introducing fish to infants' diets may offer important allergy protection.
Overall, while maternal intake showed no significant benefits, early fish consumption appears promising for reducing eczema.
Read More
8
Omega-3s improve eczema symptoms
Dietary polyunsaturated fatty acids and non-digestible oligosaccharides reduce dermatitis in mice.
We investigated how oral fatty acids and carbohydrates influence eczema symptoms. In a pilot study with OVA-sensitized mice, those fed a diet rich in arachidonic acid/docosahexaenoic acid (AA/DHA) and galactooligosaccharides/polydextrose (GOS/PDX) showed pronounced skin improvement.
The mice demonstrated reduced skin inflammation and improved skin barrier function. Specifically, the combination of AA/DHA and GOS/PDX yielded the most benefits. These findings suggest dietary additions may effectively support humans dealing with atopic eczema.
My skin is fragile due to weak intestines, leading to issues like acne and eczema. Combining it with NOW Vitamin C and pantothenic acid has helped significantly since I began taking it. Previously, I struggled with eczema around my hands, which has improved notably. I appreciate Omega-3 and consider it essential for my well-being, especially in managing eczema.
Read More
9
Soothes eczema
2 people found this helpful
Works perfectly for me, though I’m saddened that they no longer ship to Spain. I’ve taken it for years, and it effectively lowers inflammation and soothes my eczema.
Read More
9
Skin improvement
I bought fish oil for my husband, who has dry skin and eczema. After two weeks, his skin showed noticeable improvement!
Read More
9
Eczema relief
I was initially sceptical about any fishy taste, but there’s hardly any! It significantly healed my eczema, and while I need to take four pills a day, I’ve adjusted my dosage. It also helps with muscle soreness and promotes hair growth.
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7.5
Antioxidant properties
122 people found this helpful
Omega-3 has been shown to have a curative effect on various body systems. It can help prevent cardiovascular and gastrointestinal diseases, and it improves memory and vision. A lack of Omega-3 can lead to atherosclerotic plaques. This supplement helps with skin issues like eczema, boosts immunity, and has antioxidant properties. I recommend it for better health.
Eczema, also known as atopic dermatitis, is a chronic skin condition characterized by inflamed, itchy, and red patches on the skin. It is most commonly seen in children but can occur at any age. The condition can range from mild to severe and often leads to dry, scaly skin that can become cracked or even bleed. Eczema is believed to be related to a combination of genetic predisposition, skin barrier dysfunction, and environmental factors, including allergens, irritants, and stress.
Treatment for eczema often involves a multi-faceted approach, including the use of moisturizers to keep the skin hydrated, topical corticosteroids to reduce inflammation, and, in some cases, antihistamines to alleviate itching. Identifying and avoiding triggers such as certain soaps, fabrics, or foods can also play a crucial role in managing the condition. While there is currently no cure for eczema, ongoing advancements in research have led to the development of new therapies, including biologic medications that target specific components of the immune response, offering hope for those with moderate to severe cases.
Omega-3 fish oil is a nutritional supplement derived from the fatty tissues of fish, particularly fatty fish like salmon, mackerel, and sardines. It is rich in omega-3 fatty acids, which are essential fats that the body cannot produce on its own. The most significant types of omega-3s found in fish oil are eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), both of which are known for their numerous health benefits. These include reducing inflammation, supporting heart health, and promoting brain function.
Incorporating omega-3 fish oil into your diet can be beneficial if you don’t consume enough fish regularly. Many health experts recommend oily fish as a part of a balanced diet due to their high omega-3 content. For those who find it difficult to include fish in their meals, fish oil supplements can offer a convenient alternative, providing the same essential fatty acids in concentrated form. However, it’s essential to choose high-quality supplements that are third-party tested for purity and potency to avoid contaminants such as heavy metals or other toxins that can impact health.
While research on the effects of omega-3 fish oil on eczema is still evolving, there is some evidence suggesting that omega-3 fatty acids can be beneficial for skin health. Omega-3s, which are found in fish oil, have anti-inflammatory properties that may help reduce the inflammation associated with eczema flare-ups. Some studies indicate that taking omega-3 supplements could improve overall skin barrier function and moisture, potentially leading to fewer and less severe eczema symptoms.
However, it's important to note that results can vary from person to person. Some individuals may experience relief from their eczema symptoms with the inclusion of omega-3 fish oil, while others may not notice significant changes. Consulting with a healthcare professional before starting any new supplement is wise, especially if you have eczema or other related skin conditions. They can provide personalized recommendations and ensure that fish oil is a suitable option for your specific situation.
Based on user reviews, the time it typically takes to see improvements in eczema after starting an Omega-3 supplement can vary, but many users report noticeable results within a couple of weeks. For instance, one user mentioned a significant improvement in their husband's skin just two weeks after beginning supplementation Read Review. Other users have shared that while they experienced benefits in inflammation and skin condition relatively quickly, consistent usage over several months appeared to yield more substantial effects, with one noting it took several years to see improvements Read Review.
Another user stated that regular use of Omega-3 helped them moisturize their hands, which were adversely affected by eczema, leading to a reduction in their previous reliance on specialized treatments Read Review. Overall, while some users report results within weeks, others suggest that efficacy may enhance over longer periods of consistent use, making it a worthwhile supplement for managing eczema.
Research on supplements for eczema, particularly omega-3 fatty acids, suggests a mixed but promising potential for benefits. Studies indicate that maternal intake of omega-3 fatty acids during pregnancy is associated with a reduced risk of eczema in children, especially in at-risk populations. For instance, one study found that increased fish oil intake might help reduce the prevalence and severity of atopic eczema in infants during their first year of life [5]. Additionally, another study indicated that children who consumed fish within their first year had a significantly lower chance of developing eczema by age six [3]. While prenatal supplementation tends to be linked to IgE-mediated eczema protection, the overall effectiveness can vary among different children [7].
On a different front, specific components of omega-3 fatty acids, such as eicosapentaenoic acid (EPA), have demonstrated promising effects on reducing eczema symptoms in clinical trials, particularly for children [17]. Research involving animal models supports the notion that EPA can enhance skin barrier function and alleviate symptoms associated with eczema [4]. However, the efficacy of omega-3 fatty acids is inconsistent across various studies, implying that more comprehensive and longer-term research is necessary to solidify these findings before any definitive recommendations can be made [9]. Overall, while some research points toward potential benefits of supplementation for alleviating eczema, further investigation is essential to understand its effectiveness fully.
Users have reported a variety of positive improvements regarding their eczema symptoms after incorporating Omega-3 supplements into their routines. For instance, one user noted a significant reduction in eczema around their hands after combining Omega-3 with Vitamin C and other supplements Read Review. Another user shared that their skin showed noticeable improvement just two weeks after starting the supplement, emphasizing its effectiveness in managing dry skin and eczema Read Review.
Many users consistently mention improvements in skin hydration and overall skin condition, which they attribute to regular Omega-3 supplementation. One individual remarked that the supplement helped moisturize their eczema-affected hands and decreased their reliance on specialized treatments Read Review. Furthermore, some users believe in the long-term benefits, with one stating they needed several years for their eczema symptoms to show improvements, reinforcing that individual results can vary widely Read Review. Overall, while many users reported quick benefits, the general consensus suggests that sustained use may yield the best results in managing eczema.
Users have reported positive outcomes when combining Omega-3 supplements with other vitamins for managing eczema. One review specifically mentions that pairing Omega-3 with NOW Vitamin C and pantothenic acid led to significant improvements in eczema, particularly around the hands Read Review. Another user stated that they alternate Omega-3 with vitamin D3 for enhanced health benefits, implying that such combinations could be effective in addressing skin conditions Read Review. This trend suggests that users see added value in stacking supplements to bolster overall skin health.
Additionally, several users referenced the overall hydration and healing effects of Omega-3 on their skin, which may be further enhanced when taken alongside other supportive supplements. For example, one individual noted a reduction in their reliance on specialized treatments for eczema due to the moisturizing effects of Omega-3 Read Review. These reviews indicate a promising synergy when Omega-3 is combined with other vitamins, potentially leading to better management of eczema symptoms and improved skin condition.
When it comes to using Omega-3 fish oil for treating eczema, emerging research suggests that the fatty acid eicosapentaenoic acid (EPA) may have particular benefits. A study conducted on children with atopic dermatitis showed that doses of 250 mg of EPA taken twice daily for four weeks resulted in noticeable improvements in eczema severity, as measured by the SCORAD index, which reflects the severity of atopic dermatitis symptoms [17]. This highlights that a targeted EPA supplementation could be an effective and well-tolerated option for managing eczema in children.
Additionally, research indicates that maternal intake of docosahexaenoic acid (DHA) during pregnancy is associated with a reduced incidence of eczema among infants, especially those at higher risk of allergies. One study reported that infants whose mothers supplemented with DHA experienced significantly lower rates of IgE-associated eczema compared to those who did not receive DHA supplements [18]. While the optimal dosing strategies are still being explored, these findings suggest that incorporating higher levels of EPA and DHA—either through diet or supplementation—could potentially benefit those dealing with eczema.
9
Skin improvement
I bought fish oil for my husband, who has dry skin and eczema. After two weeks, his skin showed noticeable improvement!
7.5
Eczema improvement
Good. There are numerous benefits to be gained; it took me several years to see improvements with my eczema and nasal allergies, and I will continue using it.
7.5
Moisturises skin
1 people found this helpful
I consistently take Omega-3, which is essential for my health. It's helped moisturise my hands, which were affected by eczema, reducing my reliance on special treatments.
7.5
Eczema management
19 people found this helpful
My skin is fragile due to weak intestines, leading to issues like acne and eczema. Combining it with NOW Vitamin C and pantothenic acid has helped significantly since I began taking it. Previously, I struggled with eczema around my hands, which has improved notably. I appreciate Omega-3 and consider it essential for my well-being, especially in managing eczema.
7.5
Improves eczema
2 people found this helpful
Omega-3 positively impacts various body systems, preventing diseases and improving metabolism. It helps with conditions like eczema and boosts immunity. I alternate taking two capsules every other day with vitamin D3 for better health.
7
Omega-3’s role in allergy prevention
Can Early Omega-3 Fatty Acid Exposure Reduce Risk of Childhood Allergic Disease?
We explored the potential benefits of omega-3 fatty acids found in fish oils during pregnancy to see if they could decrease the risk of allergic diseases in children. Our findings indicate that increased fish oil intake may indeed reduce the prevalence and severity of atopic eczema within the first year of life.
However, while there are some positive associations, the results from various studies are inconsistent. There’s no clear consensus on the effectiveness of omega-3s in preventing allergies across all children. Thus, more research is needed to confirm these findings and fortify strategies for preventing allergic conditions.
7
Fish consumption reduces eczema risk
Fish Consumption at One Year of Age Reduces the Risk of Eczema, Asthma and Wheeze at Six Years of Age.
We examined the effects of dietary fish on the risk of eczema and other allergic diseases in children. Using data from a study in Trondheim, we found that children who ate fish at least once a week during their first year had a 28-34% lower chance of developing eczema, asthma, and wheeze by age six.
While cod liver oil showed potential benefits, the strongest results came from regular fish consumption. Surprisingly, we didn’t see any clear impacts related to mothers’ fish intake during pregnancy or nursing.
7
Limited evidence for allergy prevention
Maternal prenatal and/or postnatal n-3 long chain polyunsaturated fatty acids (LCPUFA) supplementation for preventing allergies in early childhood.
We explored the impact of omega-3 long-chain polyunsaturated fatty acids (n-3 LCPUFA) supplementation in pregnant and breastfeeding women on their children’s allergy outcomes, including eczema. The study analyzed data from eight trials involving over 3,300 women.
While supplementation showed a significant reduction in IgE-mediated eczema for children aged 12 to 36 months, the overall effect on allergies was limited. Beyond this age range, no meaningful differences were detected, indicating that omega-3 may not be a reliable preventive measure for allergies in children over time.
9
Eicosapentaenoic Acid reduces eczema
Evaluating the Effect of Eicosapentaenoic Acid in Children With Atopic Dermatitis: A Randomized Triple-Blind Clinical Trial.
We embarked on a study to find out how dietary eicosapentaenoic acid (EPA) could help children suffering from atopic dermatitis, a common form of eczema. In a randomized triple-blind clinical trial, 48 children with this condition were divided into two groups—one received 250 mg of EPA twice daily, while the other received a placebo for four weeks.
Our observations showed noticeable improvements in those who took EPA. After just two weeks, participants in the EPA group reported a reduction in their SCORAD scores, which are used to measure the severity of atopic dermatitis. The scores went down significantly compared to the placebo group. After four weeks, the number of children needing corticosteroids to manage their symptoms was also lower in the EPA group.
Despite these positive results, both groups reported few adverse effects, indicating that EPA supplementation is generally well-received. Overall, we conclude that adding EPA to the diet may be an effective and safe strategy for reducing eczema severity in children.
8
EPA-E improves eczema-like symptoms
Eicosapentaenoic acid ethyl ester ameliorates atopic dermatitis-like symptoms in special diet-fed hairless mice, partly by restoring covalently bound ceramides in the stratum corneum.
We explored how eicosapentaenoic acid ethyl ester (EPA-E), a component of omega-3 fish oil, affects atopic dermatitis-like symptoms in mice. This study showed that EPA-E could improve skin barrier issues and reduce itching in mice with conditions similar to human eczema.
We observed that the treatment helped restore important lipids in the skin, known as ceramides. These results suggest that EPA-E may offer a promising approach to treat eczema in people, but further testing is needed.
7
Omega-3’s potential against eczema
Dietary n-3 LC-PUFA during the perinatal period as a strategy to minimize childhood allergic disease.
We examined the effects of omega-3 long-chain polyunsaturated fatty acids (LC-PUFA) during pregnancy to see if it helps lower the risk of childhood allergic diseases, including eczema.
Research shows that mothers taking these supplements during pregnancy may give birth to fewer children with atopic eczema, especially in those at high risk for allergies.
However, studies focusing solely on postnatal supplementation had mixed outcomes—some found no significant benefits.
Overall, it seems that using omega-3 supplements before allergies manifest could be beneficial, but more research is needed to determine the best timing and long-term effects.
7
DHA supplementation reduces eczema risk
Fish oil supplementation in pregnancy and lactation may decrease the risk of infant allergy.
We investigated the effects of docosahexaenoic acid (DHA), a type of omega-3 fatty acid, on the incidence of eczema in infants. Our study involved 145 pregnant women who had allergies or family histories of allergies. They participated in a randomized, placebo-controlled trial where some received daily supplements of DHA during pregnancy and breastfeeding, while others received a placebo.
We found that infants whose mothers took DHA experienced a lower prevalence of eczema related to immunoglobulin E (IgE). Specifically, only 8% of infants in the DHA group developed IgE-associated eczema compared to a concerning 24% in the placebo group, marking a significant difference.
This suggests that maternal omega-3 supplementation, particularly with DHA, could play a beneficial role in reducing the risk of eczema in infants with a family history of allergies. Thus, incorporating omega-3 fatty acids in a mother’s diet during pregnancy and lactation may be a simple yet effective strategy to help protect babies from developing eczema.
References
Jia Y, Huang Y, Wang H, Jiang H. Effect of Prenatal Omega-3 Polyunsaturated Fatty Acid Supplementation on Childhood Eczema: A Systematic Review and Meta-Analysis. Int Arch Allergy Immunol. 2023;184:21. 10.1159/000526366
Peng S, Du Z, He Y, Zhao F, Chen Y, et al. Association of Maternal Erythrocyte PUFA during Pregnancy with Offspring Allergy in the Chinese Population. Nutrients. 2022;14. 10.3390/nu14112312
Øien T, Schjelvaag A, Storrø O, Johnsen R, Simpson MR. Fish Consumption at One Year of Age Reduces the Risk of Eczema, Asthma and Wheeze at Six Years of Age. Nutrients. 2019;11. 10.3390/nu11091969
Fujii M, Ohyanagi C, Kawaguchi N, Matsuda H, Miyamoto Y, et al. Eicosapentaenoic acid ethyl ester ameliorates atopic dermatitis-like symptoms in special diet-fed hairless mice, partly by restoring covalently bound ceramides in the stratum corneum. Exp Dermatol. 2018;27:837. 10.1111/exd.13507
Miles EA, Calder PC. Can Early Omega-3 Fatty Acid Exposure Reduce Risk of Childhood Allergic Disease?. Nutrients. 2017;9. 10.3390/nu9070784
Zhang GQ, Liu B, Li J, Luo CQ, Zhang Q, et al. Fish intake during pregnancy or infancy and allergic outcomes in children: A systematic review and meta-analysis. Pediatr Allergy Immunol. 2017;28:152. 10.1111/pai.12648
Gunaratne AW, Makrides M, Collins CT. Maternal prenatal and/or postnatal n-3 long chain polyunsaturated fatty acids (LCPUFA) supplementation for preventing allergies in early childhood. Cochrane Database Syst Rev. 2015;2015:CD010085. 10.1002/14651858.CD010085.pub2
Chisaguano AM, Montes R, Castellote AI, Morales E, Júlvez J, et al. Elaidic, vaccenic, and rumenic acid status during pregnancy: association with maternal plasmatic LC-PUFAs and atopic manifestations in infants. Pediatr Res. 2014;76:470. 10.1038/pr.2014.119
Makrides M, Gunaratne AW, Collins CT. Dietary n-3 LC-PUFA during the perinatal period as a strategy to minimize childhood allergic disease. Nestle Nutr Inst Workshop Ser. 2013;77:155. 10.1159/000351398
Weise C, Ernst D, van Tol EA, Worm M. Dietary polyunsaturated fatty acids and non-digestible oligosaccharides reduce dermatitis in mice. Pediatr Allergy Immunol. 2013;24:361. 10.1111/pai.12073
Montes R, Chisaguano AM, Castellote AI, Morales E, Sunyer J, et al. Fatty-acid composition of maternal and umbilical cord plasma and early childhood atopic eczema in a Spanish cohort. Eur J Clin Nutr. 2013;67:658. 10.1038/ejcn.2013.68
D'Vaz N, Meldrum SJ, Dunstan JA, Lee-Pullen TF, Metcalfe J, et al. Fish oil supplementation in early infancy modulates developing infant immune responses. Clin Exp Allergy. 2012;42:1206. 10.1111/j.1365-2222.2012.04031.x
Palmer DJ, Sullivan T, Gold MS, Prescott SL, Heddle R, et al. Effect of n-3 long chain polyunsaturated fatty acid supplementation in pregnancy on infants' allergies in first year of life: randomised controlled trial. BMJ. 2012;344:e184. 10.1136/bmj.e184
Kunitsugu I, Okuda M, Murakami N, Hashimoto M, Yamanishi R, et al. Self-reported seafood intake and atopy in Japanese school-aged children. Pediatr Int. 2012;54:233. 10.1111/j.1442-200X.2011.03542.x
Furuhjelm C, Warstedt K, Fagerås M, Fälth-Magnusson K, Larsson J, et al. Allergic disease in infants up to 2 years of age in relation to plasma omega-3 fatty acids and maternal fish oil supplementation in pregnancy and lactation. Pediatr Allergy Immunol. 2011;22:505. 10.1111/j.1399-3038.2010.01096.x
Sato A, Sato G, Yabuki A, Ogawa Y, Nemoto H, et al. Ameliorative effects of squid phospholipids from Todarodes pacificus on atopic dermatitis-like lesions in NC/Nga mice. Arch Dermatol Res. 2025;317:239. 10.1007/s00403-024-03773-9
Mirrahimi B, Moazemi M, Eslami N, Jamshidi E, Mir M, et al. Evaluating the Effect of Eicosapentaenoic Acid in Children With Atopic Dermatitis: A Randomized Triple-Blind Clinical Trial. J Pediatr Pharmacol Ther. 2023;28:29. 10.5863/1551-6776-28.1.29
Furuhjelm C, Warstedt K, Larsson J, Fredriksson M, Böttcher MF, et al. Fish oil supplementation in pregnancy and lactation may decrease the risk of infant allergy. Acta Paediatr. 2009;98:1461. 10.1111/j.1651-2227.2009.01355.x
Miyake Y, Sasaki S, Tanaka K, Ohya Y, Matsunaga I, et al. Relationship between dietary fat and fish intake and the prevalence of atopic eczema in pregnant Japanese females: baseline data from the Osaka Maternal and Child Health Study. Asia Pac J Clin Nutr. 2008;17:612.
Koch C, Dölle S, Metzger M, Rasche C, Jungclas H, et al. Docosahexaenoic acid (DHA) supplementation in atopic eczema: a randomized, double-blind, controlled trial. Br J Dermatol. 2008;158:786. 10.1111/j.1365-2133.2007.08430.x