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NOW Supplements Omega-3
SCIENTIFIC SCORE
Moderately Effective
Based on 45 Researches
8
USERS' SCORE
Good
Based on 164 Reviews
8.9
Supplement Facts
Serving Size:   2 Softgels
Amount Per Serving
%DV
Calories
20
 
Total Fat
2 g
3%**
Saturated Fat
0.5 g
3%**
Polyunsaturated Fat
1 g
Monounsaturated Fat
0.5 g
Fish Oil Concentrate
2 g (2,000 mg)
Eicosapentaenoic Acid (EPA)
360 mg
Docosahexaenoic Acid (DHA)
240 mg

Top Medical Research Studies

9
Omega-3 EPA+DHA improves cholesterol
EPA+DHA, but not ALA, Improved Lipids and Inflammation Status in Hypercholesterolemic Adults: A Randomized, Double-Blind, Placebo-Controlled Trial.
Highly relevant findings on omega-3s
We conducted a comprehensive trial to understand how different types of omega-3 fatty acids affect cholesterol levels and inflammation in adults struggling with high cholesterol.

Over 12 weeks, participants took various doses of omega-3s, including EPA and DHA, revealing notable benefits. Those receiving higher doses of EPA and DHA saw their triglycerides drop significantly—by up to 15.78%—compared to controls.

Interestingly, ALA supplementation did not lead to improvements in cholesterol or inflammation status, highlighting the superior role of EPA and DHA in managing these health issues.
Read More
9
Scallop oil significantly reduces cholesterol
Comparison of the Cholesterol-Lowering Effect of Scallop Oil Prepared from the Internal Organs of the Japanese Giant Scallop (Patinopecten yessoensis), Fish Oil, and Krill Oil in Obese Type II Diabetic KK-A Mice.
High relevance to cholesterol treatment.
We investigated how different oils, including newly produced scallop oil, fish oil, and krill oil, impact cholesterol levels in obese type II diabetic mice. Our study involved feeding these groups various high-fat diets for 42 days.

Remarkably, the scallop oil group showed a significant reduction in cholesterol levels in both serum and liver, while the fish oil and krill oil groups did not exhibit such benefits. The findings suggest that scallop oil might be a promising option for managing cholesterol and preventing related health issues.
Read More
9
Omega-3s improve cholesterol parameters
Fish oil diet effects on alveolar bone loss, in hypercholesterolemic rats.
Moderate relevance to study topic
We examined how swapping a saturated fat diet for omega-3 polyunsaturated fatty acids (n-3PUFAs) affects cholesterol and bone health in hypercholesterolemic rats.

In our study, rats that shifted to an n-3PUFA diet saw a notable decrease in serum lipids. While the diet appeared to positively impact their bone loss linked to periodontitis, rats on the n-3PUFA diet showed results similar to those on a commercial diet, indicating no major advantage of fish oil over a balanced diet.

Overall, our findings suggest that while omega-3s can help with cholesterol, they don't offer significant improvements over typical diets in these conditions.
Read More

Most Useful Reviews

9.5
Immune system boost
We consistently order these Omega-3 capsules. They have significantly strengthened our immune systems and normalised my mother's high cholesterol levels. They have no aftertaste and are easy to swallow, even for children. Their cost is very competitive, making them an excellent choice.
Read More
10
Lower cholesterol levels
My husband has high cholesterol, prompting our doctor to recommend Omega-3 supplementation. We chose this product for its value, and he took two capsules daily. After 2.5 months, his cholesterol levels normalised. The benefits of this Omega are invaluable, and I believe ongoing use is essential.
Read More
9.5
Improved blood work
I take omega-3 capsules for daily polyunsaturated fatty acid intake. They improve my immune and endocrine systems, lower my high cholesterol, and benefit my skin, hair, and nails. I take four capsules daily, combining them with vitamin D3.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 45 Researches
8
  • All Researches
9
Antarctic krill oil aids cholesterol
Antarctic Krill Oil Supplementation Attenuates Hypercholesterolemia, Fatty Liver, and Oxidative Stress in Diet-Induced Obese Mice.
Significant relevance for obesity treatment
We aimed to understand how Antarctic krill oil (ESKO) affects cholesterol levels, particularly in relation to obesity. Through our study involving mice, we observed that ESKO helped reduce oxidative stress and improve cholesterol metabolism.

While a high-fat diet usually worsens cholesterol levels, ESKO demonstrated a protective effect by reducing fat accumulation and promoting better metabolic health. This suggests that krill oil could be a promising option for managing high cholesterol and obesity-related issues.
Read More
9
CA-rich fish oils lower cholesterol
Effects of diets containing fish oils or fish oil concentrates with high cetoleic acid content on the circulating cholesterol concentration in rodents. A systematic review and meta-analysis.
Relevant research on cholesterol management
We investigated whether cetoleic acid (CA), a healthy fat found in certain fish, can help lower cholesterol levels in rodents. Our systematic review included 12 studies, assessing how CA-rich fish oils influenced total cholesterol compared to regular diets.

The results showed a significant reduction in cholesterol levels in rodents that consumed CA-rich oils. However, it’s important to note that the risk of bias in the studies varied, making our conclusions tentative. Overall, these findings suggest CA-rich fish oils could play a beneficial role in heart health, but further research in humans is needed.
Read More
9
Scallop oil significantly reduces cholesterol
Comparison of the Cholesterol-Lowering Effect of Scallop Oil Prepared from the Internal Organs of the Japanese Giant Scallop (Patinopecten yessoensis), Fish Oil, and Krill Oil in Obese Type II Diabetic KK-A Mice.
High relevance to cholesterol treatment.
We investigated how different oils, including newly produced scallop oil, fish oil, and krill oil, impact cholesterol levels in obese type II diabetic mice. Our study involved feeding these groups various high-fat diets for 42 days.

Remarkably, the scallop oil group showed a significant reduction in cholesterol levels in both serum and liver, while the fish oil and krill oil groups did not exhibit such benefits. The findings suggest that scallop oil might be a promising option for managing cholesterol and preventing related health issues.
Read More
9
Omega-3 effective for heart risk
The case for adding eicosapentaenoic acid (icosapent ethyl) to the ABCs of cardiovascular disease prevention.
High relevance for cardiovascular care
We examined the role of eicosapentaenoic acid (EPA), specifically icosapent ethyl, in reducing cardiovascular disease risks. Approved by the FDA, this omega-3 treatment showed a notable 25% reduction in major heart events for high-risk patients. These patients already had controlled cholesterol but elevated triglyceride levels.

Importantly, while EPA proved effective, mixed omega-3 products lacking substantial evidence for heart health did not provide the same benefits. We believe adding EPA-only formulations to cardiovascular prevention guidelines is essential for at-risk individuals.
Read More
9
8-HEPE benefits cholesterol management
8-HEPE-Concentrated Materials from Pacific Krill Improve Plasma Cholesterol Levels and Hepatic Steatosis in High Cholesterol Diet-Fed Low-Density Lipoprotein (LDL) Receptor-Deficient Mice.
Highly relevant to cholesterol research
We explored how 8-hydroxyeicosapentaenoic acid (8-HEPE), derived from Pacific krill, could improve cholesterol levels in mice commonly used for dyslipidemia studies.

Over eighteen weeks, mice on a high-cholesterol diet receiving 8-HEPE showed significantly higher levels of good HDL cholesterol, alongside lower levels of bad LDL cholesterol and liver triglycerides.

This suggests that 8-HEPE may enhance lipid profiles and liver health by influencing certain genes in macrophages. While promising, further research is needed to confirm these benefits in humans.
Read More

User Reviews

USERS' SCORE
Good
Based on 164 Reviews
8.9
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
Immune system boost
We consistently order these Omega-3 capsules. They have significantly strengthened our immune systems and normalised my mother's high cholesterol levels. They have no aftertaste and are easy to swallow, even for children. Their cost is very competitive, making them an excellent choice.
Read More
10
Lower cholesterol levels
My husband has high cholesterol, prompting our doctor to recommend Omega-3 supplementation. We chose this product for its value, and he took two capsules daily. After 2.5 months, his cholesterol levels normalised. The benefits of this Omega are invaluable, and I believe ongoing use is essential.
Read More
9.5
Improved blood work
I take omega-3 capsules for daily polyunsaturated fatty acid intake. They improve my immune and endocrine systems, lower my high cholesterol, and benefit my skin, hair, and nails. I take four capsules daily, combining them with vitamin D3.
9.5
Normal cholesterol
These easy-to-swallow capsules have no fishy smell. After 2.5 months, blood tests showed my cholesterol level at a normal 5.6! This omega truly works.
9.5
Reduced health risks
This omega-3 fights high cholesterol and normalises blood pressure, while also reducing obesity-related disease risks. The reasonable price means it lasts a long time.
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