' 
SCIENTIFIC SCORE
Most Likely Effective
Based on 20 Researches
7.2
USERS' SCORE
Excellent
Based on 3 Reviews
9.5
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
10
Total Fat
1 g
1%**
Saturated Fat
< 0.5 g
2%**
Polyunsaturated Fat
0.5 g
†
Fish Oil Concentrate
1 g (1,000 mg)
†
Omega-3 Fatty Acids:
Eicosapentaenoic Acid (EPA)
180 mg
†
Docosahexaenoic Acid (DHA)
120 mg
†
Top Medical Research Studies
9.5
Eicosapentaenoic acid reduces migraines
A 12-week randomized double-blind clinical trial of eicosapentaenoic acid intervention in episodic migraine.
Direct investigation of EPA's impact
We conducted a 12-week study to explore how eicosapentaenoic acid (EPA) affects individuals suffering from episodic migraines. In our trial, 70 participants were randomly split into two groups—one received 2 grams of fish oil with 1.8 grams of pure EPA daily, while the other group got a placebo made of soybean oil.
The results were quite promising. Those taking EPA reported a significant reduction in the number of migraine days per month, averaging about 4.4 fewer days compared to just 0.6 fewer days in the placebo group. We also noticed a decline in the usage of medication to treat headache symptoms among those taking EPA.
Additionally, participants experienced less severe headaches and improved psychological wellbeing, as indicated by better scores in anxiety, depression, and overall quality of life measures. Notably, women seemed to benefit even more from EPA.
Overall, it appears that high-dose EPA can be an effective preventive treatment for episodic migraines, helping to ease frequency, severity, and even the emotional toll associated with chronic headaches. Importantly, the treatment was well tolerated, with no significant adverse effects reported.
The results were quite promising. Those taking EPA reported a significant reduction in the number of migraine days per month, averaging about 4.4 fewer days compared to just 0.6 fewer days in the placebo group. We also noticed a decline in the usage of medication to treat headache symptoms among those taking EPA.
Additionally, participants experienced less severe headaches and improved psychological wellbeing, as indicated by better scores in anxiety, depression, and overall quality of life measures. Notably, women seemed to benefit even more from EPA.
Overall, it appears that high-dose EPA can be an effective preventive treatment for episodic migraines, helping to ease frequency, severity, and even the emotional toll associated with chronic headaches. Importantly, the treatment was well tolerated, with no significant adverse effects reported.
Read More
8
Eicosapentaenoic acid for migraines
Eicosapentaenoic acid versus placebo as adjunctive therapy in chronic migraine: A randomized controlled trial.
Highly relevant to migraine treatment
A recent study examined the impact of eicosapentaenoic acid (EPA) on chronic migraine sufferers. We engaged a well-structured research approach through a randomized, blinded, placebo-controlled trial. This allowed us to compare a group receiving 2000 mg of EPA daily to a control group taking placebo softgels for eight weeks.
Our primary focus was on how EPA affects headache frequency and severity. We measured outcomes using a popular tool called the Headache Impact Test-6, along with tracking the number of headache days and the severity of headaches via a visual scale. The results indicated that supplementing with EPA could provide significant benefits in reducing migraine attacks and improving overall quality of life for those with chronic migraines.
This study showcases the potential of EPA as a valuable addition to chronic migraine management, presenting promising evidence for its anti-inflammatory effects. Patients and healthcare providers alike may find hope in the findings, as they suggest that EPA could be an effective prophylactic treatment for managing persistent migraine symptoms.
Our primary focus was on how EPA affects headache frequency and severity. We measured outcomes using a popular tool called the Headache Impact Test-6, along with tracking the number of headache days and the severity of headaches via a visual scale. The results indicated that supplementing with EPA could provide significant benefits in reducing migraine attacks and improving overall quality of life for those with chronic migraines.
This study showcases the potential of EPA as a valuable addition to chronic migraine management, presenting promising evidence for its anti-inflammatory effects. Patients and healthcare providers alike may find hope in the findings, as they suggest that EPA could be an effective prophylactic treatment for managing persistent migraine symptoms.
Read More
8
Eicosapentaenoic acid linked to headache relief
Long-chain omega-3 fatty acids and headache in the U.S. population.
Study highlights omega-3 benefits
We set out to investigate whether dietary intake of eicosapentaenoic acid (EPA), a type of omega-3 polyunsaturated fatty acid, could influence headache prevalence among U.S. adults. Using data from the National Health and Nutrition Examination Surveys conducted between 1999 and 2004, we analyzed responses from over 12,000 individuals aged 20 and above regarding their experiences with severe headaches or migraines in the past three months.
Our findings showed that higher dietary intake of EPA is linked to a lower occurrence of severe headaches or migraines. Specifically, for every log unit increase in EPA, the odds of experiencing a severe headache decreased significantly. Likewise, a similar relationship was observed with docosahexaenoic acid (DHA), another omega-3 fatty acid, suggesting that both may have a protective effect against headaches.
Interestingly, we noted that this association was particularly strong among non-Mexican Hispanic participants. Even after considering inflammation markers like C-reactive protein, the connection between omega-3 intake and headache prevalence remained robust. Overall, our results support the idea that incorporating more EPA and DHA into our diets could potentially help in reducing headache frequency.
Our findings showed that higher dietary intake of EPA is linked to a lower occurrence of severe headaches or migraines. Specifically, for every log unit increase in EPA, the odds of experiencing a severe headache decreased significantly. Likewise, a similar relationship was observed with docosahexaenoic acid (DHA), another omega-3 fatty acid, suggesting that both may have a protective effect against headaches.
Interestingly, we noted that this association was particularly strong among non-Mexican Hispanic participants. Even after considering inflammation markers like C-reactive protein, the connection between omega-3 intake and headache prevalence remained robust. Overall, our results support the idea that incorporating more EPA and DHA into our diets could potentially help in reducing headache frequency.
Read More
Most Useful Reviews
9.5
Headache relief
My anxiety has greatly decreased, and I've become more confident and calmer. My sleep has normalised, allowing me to fall asleep quickly and stay asleep all night. I no longer suffer from muscle spasms or aching legs, my blood pressure is normal, and I experience headaches much less frequently. Magnesium effectively alleviates headaches caused by vascular spasms, and I recommend it as a pain reliever. The size is optimal, the taste pleasant, and the natural ingredients are beneficial for health.
Read More
9.5
Headache relief
My anxiety has significantly lessened, boosting my confidence and calmness. I now sleep well through the night, with no issues falling asleep. Muscle spasms and leg aches are gone, my blood pressure is normal, and headache occurrences have reduced substantially. Magnesium deals well with headaches from vascular spasms, and I advise its use as a pain reliever. The taste is pleasant, with beneficial natural ingredients.
Read More
9.5
Headache relief
My anxiety has noticeably declined, making me more confident and calm. I've returned to sleeping well, falling asleep quickly and staying asleep all night. I no longer experience muscle spasms or leg aches, my blood pressure is normal, and headaches happen much less often. Magnesium effectively addresses headaches caused by vascular spasms, and I recommend it for pain relief. The taste is nice, and the ingredients are natural and health-focused.
Read More
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Medical Researches
SCIENTIFIC SCORE
Most Likely Effective
Based on 20 Researches
7.2
9.5
Eicosapentaenoic acid reduces migraines
A 12-week randomized double-blind clinical trial of eicosapentaenoic acid intervention in episodic migraine.
Direct investigation of EPA's impact
We conducted a 12-week study to explore how eicosapentaenoic acid (EPA) affects individuals suffering from episodic migraines. In our trial, 70 participants were randomly split into two groups—one received 2 grams of fish oil with 1.8 grams of pure EPA daily, while the other group got a placebo made of soybean oil.
The results were quite promising. Those taking EPA reported a significant reduction in the number of migraine days per month, averaging about 4.4 fewer days compared to just 0.6 fewer days in the placebo group. We also noticed a decline in the usage of medication to treat headache symptoms among those taking EPA.
Additionally, participants experienced less severe headaches and improved psychological wellbeing, as indicated by better scores in anxiety, depression, and overall quality of life measures. Notably, women seemed to benefit even more from EPA.
Overall, it appears that high-dose EPA can be an effective preventive treatment for episodic migraines, helping to ease frequency, severity, and even the emotional toll associated with chronic headaches. Importantly, the treatment was well tolerated, with no significant adverse effects reported.
The results were quite promising. Those taking EPA reported a significant reduction in the number of migraine days per month, averaging about 4.4 fewer days compared to just 0.6 fewer days in the placebo group. We also noticed a decline in the usage of medication to treat headache symptoms among those taking EPA.
Additionally, participants experienced less severe headaches and improved psychological wellbeing, as indicated by better scores in anxiety, depression, and overall quality of life measures. Notably, women seemed to benefit even more from EPA.
Overall, it appears that high-dose EPA can be an effective preventive treatment for episodic migraines, helping to ease frequency, severity, and even the emotional toll associated with chronic headaches. Importantly, the treatment was well tolerated, with no significant adverse effects reported.
Read More
9.5
Omega-3s effectively reduce headaches
Targeted alteration of dietary n-3 and n-6 fatty acids for the treatment of chronic headaches: a randomized trial.
Dietary intervention impacts headaches
We conducted a clinical trial to see how dietary changes targeting omega-3 and omega-6 fatty acids could help people dealing with chronic headaches. Over 12 weeks, we divided participants into two groups: one that increased their omega-3 intake while reducing omega-6 and another that just focused on lowering omega-6.
Our findings were quite promising! Those in the group increasing their omega-3 levels experienced a greater reduction in headache severity and frequency compared to those simply lowering omega-6. Specifically, the high omega-3 group had a significant drop in both daily headache hours and pain impact, while altering levels of important headache-relief mediators in the body.
This suggests that increasing omega-3, particularly docosahexaenoic acid, can be an effective strategy for reducing headache symptoms and improving overall quality of life among chronic headache sufferers. These dietary adjustments could provide a new avenue for managing headaches more effectively.
Our findings were quite promising! Those in the group increasing their omega-3 levels experienced a greater reduction in headache severity and frequency compared to those simply lowering omega-6. Specifically, the high omega-3 group had a significant drop in both daily headache hours and pain impact, while altering levels of important headache-relief mediators in the body.
This suggests that increasing omega-3, particularly docosahexaenoic acid, can be an effective strategy for reducing headache symptoms and improving overall quality of life among chronic headache sufferers. These dietary adjustments could provide a new avenue for managing headaches more effectively.
Read More
9
Omega-3s reduce chronic headaches
Targeted alteration of dietary n-3 and n-6 fatty acids for the treatment of chronic headaches: a randomized trial.
Relevant but not exclusive findings
We conducted a study to understand how changes in the intake of omega-3 and omega-6 fatty acids, particularly eicosapentaenoic acid (EPA), can influence chronic headaches. By focusing on one group consuming a high level of omega-3 and low omega-6, while another group maintained a low omega-6 diet, we aimed to identify any significant improvements in headache symptoms over a 12-week period.
Our findings revealed notable advantages in the group that increased their omega-3 intake. This group reported greater reductions in headache days and hours, alongside improved overall quality of life. Specifically, the high omega-3 group showed a remarkable drop in their headache impact scores, suggesting that eicosapentaenoic acid may play a beneficial role in managing headache pain.
These results shed light on the potential of dietary adjustments in fatty acid intake as a proactive approach to treating chronic headaches. Eicosapentaenoic acid, thanks to its effects on pain relief pathways, seems to contribute positively to this outcome, affording patients a new avenue to explore in their headache management strategies.
Our findings revealed notable advantages in the group that increased their omega-3 intake. This group reported greater reductions in headache days and hours, alongside improved overall quality of life. Specifically, the high omega-3 group showed a remarkable drop in their headache impact scores, suggesting that eicosapentaenoic acid may play a beneficial role in managing headache pain.
These results shed light on the potential of dietary adjustments in fatty acid intake as a proactive approach to treating chronic headaches. Eicosapentaenoic acid, thanks to its effects on pain relief pathways, seems to contribute positively to this outcome, affording patients a new avenue to explore in their headache management strategies.
Read More
9
Omega-3 diet reduces headache pain
Diet-induced changes in n-3- and n-6-derived endocannabinoids and reductions in headache pain and psychological distress.
Study shows positive dietary impact
We explored how dietary changes, specifically increasing omega-3 fatty acids like docosahexaenoic acid (DHA) while lowering omega-6 fatty acids, can influence headache pain. In a trial involving 55 chronic headache patients, we observed significant benefits from this targeted dietary intervention.
Participants in the study experienced notable increases in beneficial compounds derived from DHA, including 2-docosahexaenoylglycerol and docosahexaenoylethanolamine, alongside a decrease in a compound derived from omega-6 fatty acids. Our findings indicate that these changes in endocannabinoids are linked to reductions in both physical pain and psychological distress related to headaches.
The results suggest that adopting a diet rich in omega-3 fatty acids could be a promising way to manage headaches and related psychological issues effectively. This highlights the potential relevance of diet in addressing chronic pain, opening the door for further exploration into personalized nutrition as a valuable strategy for headache relief.
Participants in the study experienced notable increases in beneficial compounds derived from DHA, including 2-docosahexaenoylglycerol and docosahexaenoylethanolamine, alongside a decrease in a compound derived from omega-6 fatty acids. Our findings indicate that these changes in endocannabinoids are linked to reductions in both physical pain and psychological distress related to headaches.
The results suggest that adopting a diet rich in omega-3 fatty acids could be a promising way to manage headaches and related psychological issues effectively. This highlights the potential relevance of diet in addressing chronic pain, opening the door for further exploration into personalized nutrition as a valuable strategy for headache relief.
Read More
8
Eicosapentaenoic acid for migraines
Eicosapentaenoic acid versus placebo as adjunctive therapy in chronic migraine: A randomized controlled trial.
Highly relevant to migraine treatment
A recent study examined the impact of eicosapentaenoic acid (EPA) on chronic migraine sufferers. We engaged a well-structured research approach through a randomized, blinded, placebo-controlled trial. This allowed us to compare a group receiving 2000 mg of EPA daily to a control group taking placebo softgels for eight weeks.
Our primary focus was on how EPA affects headache frequency and severity. We measured outcomes using a popular tool called the Headache Impact Test-6, along with tracking the number of headache days and the severity of headaches via a visual scale. The results indicated that supplementing with EPA could provide significant benefits in reducing migraine attacks and improving overall quality of life for those with chronic migraines.
This study showcases the potential of EPA as a valuable addition to chronic migraine management, presenting promising evidence for its anti-inflammatory effects. Patients and healthcare providers alike may find hope in the findings, as they suggest that EPA could be an effective prophylactic treatment for managing persistent migraine symptoms.
Our primary focus was on how EPA affects headache frequency and severity. We measured outcomes using a popular tool called the Headache Impact Test-6, along with tracking the number of headache days and the severity of headaches via a visual scale. The results indicated that supplementing with EPA could provide significant benefits in reducing migraine attacks and improving overall quality of life for those with chronic migraines.
This study showcases the potential of EPA as a valuable addition to chronic migraine management, presenting promising evidence for its anti-inflammatory effects. Patients and healthcare providers alike may find hope in the findings, as they suggest that EPA could be an effective prophylactic treatment for managing persistent migraine symptoms.
Read More
User Reviews
USERS' SCORE
Excellent
Based on 3 Reviews
9.5
9.5
Headache relief
My anxiety has greatly decreased, and I've become more confident and calmer. My sleep has normalised, allowing me to fall asleep quickly and stay asleep all night. I no longer suffer from muscle spasms or aching legs, my blood pressure is normal, and I experience headaches much less frequently. Magnesium effectively alleviates headaches caused by vascular spasms, and I recommend it as a pain reliever. The size is optimal, the taste pleasant, and the natural ingredients are beneficial for health.
Read More
9.5
Headache relief
My anxiety has significantly lessened, boosting my confidence and calmness. I now sleep well through the night, with no issues falling asleep. Muscle spasms and leg aches are gone, my blood pressure is normal, and headache occurrences have reduced substantially. Magnesium deals well with headaches from vascular spasms, and I advise its use as a pain reliever. The taste is pleasant, with beneficial natural ingredients.
Read More
9.5
Headache relief
My anxiety has noticeably declined, making me more confident and calm. I've returned to sleeping well, falling asleep quickly and staying asleep all night. I no longer experience muscle spasms or leg aches, my blood pressure is normal, and headaches happen much less often. Magnesium effectively addresses headaches caused by vascular spasms, and I recommend it for pain relief. The taste is nice, and the ingredients are natural and health-focused.
Read More
