Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 30 Researches
7.2
USERS' SCORE
Good
Based on 5 Reviews
8.3
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Blend of 10 Strains of Probiotic Bacteria: Lactobacillus acidophilus (La-14), Bifidobacterium lactis (Bl-04),Lactobacillus plantarum (Lp-115), Lactobacillus casei (Lc-11),Lactobacillus rhamnosus (Lr-32), Lactobacillus paracasei (Lpc-37),Bifidobacterium breve (Bb-03), Streptococcus thermophilus (St-21),Lactobacillus salivarius (Ls-33), Bifidobacterium longum (BI-05)
100 Billion CFU
*
Top Medical Research Studies
9
We explored the potential of Lactobacillus acidophilus KBL409 in addressing atopic dermatitis, a common form of eczema. By using a mouse model induced by house dust mites, we found that administering this probiotic led to significantly lower dermatitis scores and less immune cell infiltration in the skin.
Additionally, L. acidophilus KBL409 reduced serum immunoglobulin E and influenced various cytokines linked to inflammation. It also positively affected gut microbiota and concentrations of beneficial compounds, hinting at a broader impact on our immune responses. Overall, our findings suggest that L. acidophilus KBL409 may be a promising probiotic for eczema management.
Additionally, L. acidophilus KBL409 reduced serum immunoglobulin E and influenced various cytokines linked to inflammation. It also positively affected gut microbiota and concentrations of beneficial compounds, hinting at a broader impact on our immune responses. Overall, our findings suggest that L. acidophilus KBL409 may be a promising probiotic for eczema management.
9
We conducted a thorough investigation on the effects of Lactobacillus acidophilus L-92 in adults with atopic dermatitis.
In a placebo-controlled, double-blinded study, we observed 50 patients who consumed either L-92 or a placebo for 24 weeks.
Results showed that those taking L-92 had notable improvements in skin symptoms over time, including reduced severity and incidents of scratching.
Overall, the findings suggest that L-92 might play a beneficial role in managing eczema symptoms.
In a placebo-controlled, double-blinded study, we observed 50 patients who consumed either L-92 or a placebo for 24 weeks.
Results showed that those taking L-92 had notable improvements in skin symptoms over time, including reduced severity and incidents of scratching.
Overall, the findings suggest that L-92 might play a beneficial role in managing eczema symptoms.
8
We examined the effects of Lactobacillus rhamnosus HN001 on eczema prevention among children with genetic predispositions. In our double-blind, randomized, placebo-controlled study involving 331 children, we discovered that those with specific high-risk gene variants experienced lower eczema rates when treated with HN001, compared to those receiving a placebo. This suggests Lactobacillus rhamnosus might be particularly beneficial for children at greater genetic risk of eczema and may even influence the severity of eczema and related allergic conditions.
Most Useful Reviews
10
Most important supplement
It is the most crucial supplement one can take for both eczema and overall health.
9
Significant help observed
My son suffers from severe eczema, and this product has helped him immensely, more than I ever expected.
7.5
Smoother skin noticed
1 people found this helpful
Excellent Probiotics! I have suffered from eczema since childhood and have been prescribed numerous creams, but never informed that gut health affects skin. Learning to heal my gut from poor food choices, the 25 Billion probiotic wasn’t sufficient; the 100 Billion dosage significantly improved my condition, resulting in smoother skin and reduced bloating.
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 30 Researches
7.2
- All Researches
9.5
We conducted a study to see if giving probiotics to mothers during pregnancy and breastfeeding could help reduce eczema in infants at risk. This double-blind, placebo-controlled trial involved 241 mother-infant pairs, where mothers were given either specific probiotics or a placebo.
Our findings showed that infants whose mothers took Lactobacillus rhamnosus and Bifidobacterium longum had a significantly lower risk of developing eczema in their first two years. This suggests that probiotics can be a safe and effective preventive measure for high-risk infants.
Our findings showed that infants whose mothers took Lactobacillus rhamnosus and Bifidobacterium longum had a significantly lower risk of developing eczema in their first two years. This suggests that probiotics can be a safe and effective preventive measure for high-risk infants.
9
We explored the potential of Lactobacillus acidophilus KBL409 in addressing atopic dermatitis, a common form of eczema. By using a mouse model induced by house dust mites, we found that administering this probiotic led to significantly lower dermatitis scores and less immune cell infiltration in the skin.
Additionally, L. acidophilus KBL409 reduced serum immunoglobulin E and influenced various cytokines linked to inflammation. It also positively affected gut microbiota and concentrations of beneficial compounds, hinting at a broader impact on our immune responses. Overall, our findings suggest that L. acidophilus KBL409 may be a promising probiotic for eczema management.
Additionally, L. acidophilus KBL409 reduced serum immunoglobulin E and influenced various cytokines linked to inflammation. It also positively affected gut microbiota and concentrations of beneficial compounds, hinting at a broader impact on our immune responses. Overall, our findings suggest that L. acidophilus KBL409 may be a promising probiotic for eczema management.
9
We conducted a thorough investigation on the effects of Lactobacillus acidophilus L-92 in adults with atopic dermatitis.
In a placebo-controlled, double-blinded study, we observed 50 patients who consumed either L-92 or a placebo for 24 weeks.
Results showed that those taking L-92 had notable improvements in skin symptoms over time, including reduced severity and incidents of scratching.
Overall, the findings suggest that L-92 might play a beneficial role in managing eczema symptoms.
In a placebo-controlled, double-blinded study, we observed 50 patients who consumed either L-92 or a placebo for 24 weeks.
Results showed that those taking L-92 had notable improvements in skin symptoms over time, including reduced severity and incidents of scratching.
Overall, the findings suggest that L-92 might play a beneficial role in managing eczema symptoms.
9
We explored the potential of Lactobacillus rhamnosus HN001 in reducing eczema among infants at high risk. Through a robust double-blind trial, expecting mothers took the probiotic from 35 weeks pregnant and continued while breastfeeding, while infants received it from birth to two years. Remarkably, this approach halved the prevalence of eczema by ages 2 and 4. Even better, the benefits seemed to last until age 6, showing promising potential in preventing eczema and associated allergic sensitization. However, another probiotic, HN019, did not show similar effects, suggesting specific benefits tied to HN001.
9
Lactobacillus rhamnosus reduces eczema prevalence
We conducted a robust study using a double-blind randomized placebo-controlled trial to explore the impact of Lactobacillus rhamnosus HN001 on eczema in young children.
Mothers supplemented with HN001 from the 35th week of pregnancy until 6 months of breastfeeding, while infants continued taking the probiotic until age 2.
Remarkably, we found that this approach halved the prevalence of eczema by age 2, and its protective effects persisted up to age 4. HN001 may be a promising preventive measure for infants at high risk of allergic diseases.
Mothers supplemented with HN001 from the 35th week of pregnancy until 6 months of breastfeeding, while infants continued taking the probiotic until age 2.
Remarkably, we found that this approach halved the prevalence of eczema by age 2, and its protective effects persisted up to age 4. HN001 may be a promising preventive measure for infants at high risk of allergic diseases.
User Reviews
USERS' SCORE
Good
Based on 5 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
10
Most important supplement
It is the most crucial supplement one can take for both eczema and overall health.
9
Significant help observed
My son suffers from severe eczema, and this product has helped him immensely, more than I ever expected.
7.5
Smoother skin noticed
1 people found this helpful
Excellent Probiotics! I have suffered from eczema since childhood and have been prescribed numerous creams, but never informed that gut health affects skin. Learning to heal my gut from poor food choices, the 25 Billion probiotic wasn’t sufficient; the 100 Billion dosage significantly improved my condition, resulting in smoother skin and reduced bloating.
6
Gut health impact minimal
Probiotic NOW appears effective for gut health, but I haven't noticed much improvement regarding my eczema.
7.5
Long-term help noted
The ingredients are excellent. I have ongoing issues with eczema, and long-term use of this supplement does seem to help.
Frequently Asked Questions
7.5
Long-term help noted
The ingredients are excellent. I have ongoing issues with eczema, and long-term use of this supplement does seem to help.
7.5
Smoother skin noticed
1 people found this helpful
Excellent Probiotics! I have suffered from eczema since childhood and have been prescribed numerous creams, but never informed that gut health affects skin. Learning to heal my gut from poor food choices, the 25 Billion probiotic wasn’t sufficient; the 100 Billion dosage significantly improved my condition, resulting in smoother skin and reduced bloating.
9
Significant help observed
My son suffers from severe eczema, and this product has helped him immensely, more than I ever expected.
6
Gut health impact minimal
Probiotic NOW appears effective for gut health, but I haven't noticed much improvement regarding my eczema.
10
Most important supplement
It is the most crucial supplement one can take for both eczema and overall health.
9
We explored the potential of Lactobacillus acidophilus KBL409 in addressing atopic dermatitis, a common form of eczema. By using a mouse model induced by house dust mites, we found that administering this probiotic led to significantly lower dermatitis scores and less immune cell infiltration in the skin.
Additionally, L. acidophilus KBL409 reduced serum immunoglobulin E and influenced various cytokines linked to inflammation. It also positively affected gut microbiota and concentrations of beneficial compounds, hinting at a broader impact on our immune responses. Overall, our findings suggest that L. acidophilus KBL409 may be a promising probiotic for eczema management.
Additionally, L. acidophilus KBL409 reduced serum immunoglobulin E and influenced various cytokines linked to inflammation. It also positively affected gut microbiota and concentrations of beneficial compounds, hinting at a broader impact on our immune responses. Overall, our findings suggest that L. acidophilus KBL409 may be a promising probiotic for eczema management.
8
We evaluated the effects of L-92—a paraprobiotic—on young children suffering from atopic dermatitis (AD) and food allergies. In a study of 59 children aged 10 months to 3 years, participants were given either L-92 or a placebo alongside standard AD treatment over 24 weeks.
The results showed a meaningful decrease in eczema severity in the L-92 group compared to baseline evaluations. Improvements in immune markers like TARC and total IgE levels were also documented. This indicates that L-92 may serve as an effective additional treatment for young children dealing with AD and food allergies.
The results showed a meaningful decrease in eczema severity in the L-92 group compared to baseline evaluations. Improvements in immune markers like TARC and total IgE levels were also documented. This indicates that L-92 may serve as an effective additional treatment for young children dealing with AD and food allergies.
9
We conducted a thorough investigation on the effects of Lactobacillus acidophilus L-92 in adults with atopic dermatitis.
In a placebo-controlled, double-blinded study, we observed 50 patients who consumed either L-92 or a placebo for 24 weeks.
Results showed that those taking L-92 had notable improvements in skin symptoms over time, including reduced severity and incidents of scratching.
Overall, the findings suggest that L-92 might play a beneficial role in managing eczema symptoms.
In a placebo-controlled, double-blinded study, we observed 50 patients who consumed either L-92 or a placebo for 24 weeks.
Results showed that those taking L-92 had notable improvements in skin symptoms over time, including reduced severity and incidents of scratching.
Overall, the findings suggest that L-92 might play a beneficial role in managing eczema symptoms.
7
We assessed how effective nutritional supplements, including probiotics like lactobacillus acidophilus, are for managing eczema symptoms.
Our analysis revealed weak evidence overall for any one supplement, though some, especially probiotics, showed potential benefits.
Specifically, lactobacillus acidophilus is linked to positive outcomes in several studies.
However, we found that larger trials are necessary for a clearer understanding of these supplements' impact on eczema across a wider population.
Our analysis revealed weak evidence overall for any one supplement, though some, especially probiotics, showed potential benefits.
Specifically, lactobacillus acidophilus is linked to positive outcomes in several studies.
However, we found that larger trials are necessary for a clearer understanding of these supplements' impact on eczema across a wider population.
References
- Kim WK, Jang YJ, Park S, Min SG, Kwon H, et al. Lactobacillus acidophilus KBL409 Ameliorates Atopic Dermatitis in a Mouse Model. J Microbiol. 2024;62:91. doi:10.1007/s12275-024-00104-5
- Weber I, Woolhiser E, Keime N, Wasvary M, Adelman MJ, et al. Clinical Efficacy of Nutritional Supplements in Atopic Dermatitis: Systematic Review. JMIR Dermatol. 2023;6:e40857. doi:10.2196/40857
- Nakata J, Hirota T, Umemura H, Nakagawa T, Kando N, et al. Additive effect of L-92 on children with atopic dermatitis concomitant with food allergy. Asia Pac Allergy. 2019;9:e18. doi:10.5415/apallergy.2019.9.e18
- Gulliver WP, Hutton AS, Ship N. Investigating the therapeutic potential of a probiotic in a clinical population with chronic hand dermatitis. Clin Cosmet Investig Dermatol. 2018;11:265. doi:10.2147/CCID.S164748
- Yamamoto K, Yokoyama K, Matsukawa T, Kato S, Kato S, et al. Efficacy of prolonged ingestion of Lactobacillus acidophilus L-92 in adult patients with atopic dermatitis. J Dairy Sci. 2016;99:5039. doi:10.3168/jds.2015-10605
- Dotterud CK, Storrø O, Johnsen R, Oien T. Probiotics in pregnant women to prevent allergic disease: a randomized, double-blind trial. Br J Dermatol. 2010;163:616. doi:10.1111/j.1365-2133.2010.09889.x
- Kim JY, Kwon JH, Ahn SH, Lee SI, Han YS, et al. Effect of probiotic mix (Bifidobacterium bifidum, Bifidobacterium lactis, Lactobacillus acidophilus) in the primary prevention of eczema: a double-blind, randomized, placebo-controlled trial. Pediatr Allergy Immunol. 2010;21:e386. doi:10.1111/j.1399-3038.2009.00958.x
- Voigt J, Lele M. Lactobacillus rhamnosus Used in the Perinatal Period for the Prevention of Atopic Dermatitis in Infants: A Systematic Review and Meta-Analysis of Randomized Trials. Am J Clin Dermatol. 2022;23:801. doi:10.1007/s40257-022-00723-x
- Nocerino R, Bedogni G, Carucci L, Cosenza L, Cozzolino T, et al. The Impact of Formula Choice for the Management of Pediatric Cow's Milk Allergy on the Occurrence of Other Allergic Manifestations: The Atopic March Cohort Study. J Pediatr. 2021;232:183. doi:10.1016/j.jpeds.2021.01.059
- Schmidt RM, Pilmann Laursen R, Bruun S, Larnkjaer A, Mølgaard C, et al. Probiotics in late infancy reduce the incidence of eczema: A randomized controlled trial. Pediatr Allergy Immunol. 2019;30:335. doi:10.1111/pai.13018
- Murphy R, Morgan XC, Wang XY, Wickens K, Purdie G, et al. Eczema-protective probiotic alters infant gut microbiome functional capacity but not composition: sub-sample analysis from a RCT. Benef Microbes. 2019;10:5. doi:10.3920/BM2017.0191
- Wickens K, Barthow C, Mitchell EA, Kang J, van Zyl N, et al. Effects of Lactobacillus rhamnosus HN001 in early life on the cumulative prevalence of allergic disease to 11 years. Pediatr Allergy Immunol. 2018;29:808. doi:10.1111/pai.12982
- Wickens K, Barthow C, Mitchell EA, Stanley TV, Purdie G, et al. Maternal supplementation alone with Lactobacillus rhamnosus HN001 during pregnancy and breastfeeding does not reduce infant eczema. Pediatr Allergy Immunol. 2018;29:296. doi:10.1111/pai.12874
- Berni Canani R, Di Costanzo M, Bedogni G, Amoroso A, Cosenza L, et al. Extensively hydrolyzed casein formula containing Lactobacillus rhamnosus GG reduces the occurrence of other allergic manifestations in children with cow's milk allergy: 3-year randomized controlled trial. J Allergy Clin Immunol. 2017;139:1906. doi:10.1016/j.jaci.2016.10.050
- Marlow G, Han DY, Wickens K, Stanley T, Crane J, et al. Differential effects of two probiotics on the risks of eczema and atopy associated with single nucleotide polymorphisms to Toll-like receptors. Pediatr Allergy Immunol. 2015;26:262. doi:10.1111/pai.12371
- Ismail IH, Boyle RJ, Mah LJ, Licciardi PV, Tang ML. Reduced neonatal regulatory T cell response to microbial stimuli associates with subsequent eczema in high-risk infants. Pediatr Allergy Immunol. 2014;25:674. doi:10.1111/pai.12303
- Morgan AR, Han DY, Wickens K, Barthow C, Mitchell EA, et al. Differential modification of genetic susceptibility to childhood eczema by two probiotics. Clin Exp Allergy. 2014;44:1255. doi:10.1111/cea.12394
- Wickens K, Stanley TV, Mitchell EA, Barthow C, Fitzharris P, et al. Early supplementation with Lactobacillus rhamnosus HN001 reduces eczema prevalence to 6 years: does it also reduce atopic sensitization?. Clin Exp Allergy. 2013;43:1048. doi:10.1111/cea.12154
- Kuitunen M. Probiotics and prebiotics in preventing food allergy and eczema. Curr Opin Allergy Clin Immunol. 2013;13:280. doi:10.1097/ACI.0b013e328360ed66
- Rautava S, Kainonen E, Salminen S, Isolauri E. Maternal probiotic supplementation during pregnancy and breast-feeding reduces the risk of eczema in the infant. J Allergy Clin Immunol. 2012;130:1355. doi:10.1016/j.jaci.2012.09.003
- Wickens K, Black P, Stanley TV, Mitchell E, Barthow C, et al. A protective effect of Lactobacillus rhamnosus HN001 against eczema in the first 2 years of life persists to age 4 years. Clin Exp Allergy. 2012;42:1071. doi:10.1111/j.1365-2222.2012.03975.x
- Boyle RJ, Ismail IH, Kivivuori S, Licciardi PV, Robins-Browne RM, et al. Lactobacillus GG treatment during pregnancy for the prevention of eczema: a randomized controlled trial. Allergy. 2011;66:509. doi:10.1111/j.1398-9995.2010.02507.x
- Puisto R, Gómez-Gallego C, Collado MC, Turta O, Isolauri E, et al. The Role of Infant Gut Microbiota Modulation by Perinatal Maternal Probiotic Intervention in Atopic Eczema Risk Reduction. Neonatology. 2025;122:84. doi:10.1159/000540075
- Enomoto T, Sowa M, Nishimori K, Shimazu S, Yoshida A, et al. Effects of bifidobacterial supplementation to pregnant women and infants in the prevention of allergy development in infants and on fecal microbiota. Allergol Int. 2014;63:575. doi:10.2332/allergolint.13-OA-0683
- Adjibade M, Vigneron L, Delvert R, Adel-Patient K, Divaret-Chauveau A, et al. Characteristics of infant formula consumed in the first months of life and allergy in the EDEN mother-child cohort. Matern Child Nutr. 2024;20:e13673. doi:10.1111/mcn.13673
- Kim HK, Rutten NB, Besseling-van der Vaart I, Niers LE, Choi YH, et al. Probiotic supplementation influences faecal short chain fatty acids in infants at high risk for eczema. Benef Microbes. 2015;6:783. doi:10.3920/BM2015.0056
- Niers L, Martín R, Rijkers G, Sengers F, Timmerman H, et al. The effects of selected probiotic strains on the development of eczema (the PandA study). Allergy. 2009;64:1349. doi:10.1111/j.1398-9995.2009.02021.x
- Wickens K, Black PN, Stanley TV, Mitchell E, Fitzharris P, et al. A differential effect of 2 probiotics in the prevention of eczema and atopy: a double-blind, randomized, placebo-controlled trial. J Allergy Clin Immunol. 2008;122:788. doi:10.1016/j.jaci.2008.07.011
- Kirjavainen PV, Arvola T, Salminen SJ, Isolauri E. Aberrant composition of gut microbiota of allergic infants: a target of bifidobacterial therapy at weaning?. Gut. 2002;51:51.
- Isolauri E, Arvola T, Sütas Y, Moilanen E, Salminen S. Probiotics in the management of atopic eczema. Clin Exp Allergy. 2000;30:1604.
