Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8
USERS' SCORE
Good
Based on 3 Reviews
8.4
Supplement Facts
Serving Size:  1 Veg Capsule
Amount Per Serving
%DV
Blend of 10 Strains of Probiotic Bacteria: Lactobacillus acidophilus (La-14), Bifidobacterium lactis (Bl-04),Lactobacillus plantarum (Lp-115), Lactobacillus casei (Lc-11),Lactobacillus rhamnosus (Lr-32), Lactobacillus paracasei (Lpc-37),Bifidobacterium breve (Bb-03), Streptococcus thermophilus (St-21),Lactobacillus salivarius (Ls-33), Bifidobacterium longum (BI-05)
100 Billion CFU
*

Top Medical Research Studies

7
Probiotics may reduce diarrhea duration
We explored the impact of Lactobacillus acidophilus and other probiotics on children suffering from acute gastroenteritis. Our systematic review included randomized controlled trials comparing probiotics to placebos, focusing on strains available in Japan.

Although we found that probiotics like Lactobacillus acidophilus might shorten diarrhea duration by roughly one day, the evidence is not very strong.

Overall, while there were some positive signs in our findings, we recommend more research to confirm these effects and improve treatment strategies.
Read More
8
LA reduces Salmonella-induced inflammation
We explored the impact of Lactobacillus acidophilus (LA) on inflammation and oxidative stress caused by Salmonella Typhimurium in mice. After treating the mice with LA for 14 days, we observed significant improvements in gut health. LA reduced harmful serum compounds and boosted antioxidant enzyme levels, supporting better recovery.

The study also highlighted how LA regulates gut bacteria, suggesting it could be useful for disease resistance. While the research focused on animal models, it offers promising insights for future solutions in gut health and disease prevention.
Read More
We examined how the introduction of routine supplementation with Bifidobacterium bifidum and Lactobacillus acidophilus affects outcomes in very preterm infants. Through a retrospective study comparing two six-year periods, we looked at infants less than 32 weeks gestation.

Our findings revealed a significant reduction in severe necrotising enterocolitis (NEC) and death after starting probiotic administration, showing improved outcomes for these vulnerable infants. This suggests that probiotics may play a crucial role in neonatal care.
Read More

Most Useful Reviews

9
Relief from discomfort
1 people found this helpful
After suffering from gastroenteritis for a while, I tried 1000 Probiotics. After 60 days, I experienced no more discomfort in my intestines. This morning, I woke up feeling good. I’m hopeful that my gastrointestinal condition will continue to improve after using it for this duration.
Read More
7.5
Significant gut improvement
2 people found this helpful
Life changing, honestly. When I say life changing, I’m not just referring to this specific product, but to the probiotics my gastro prescribed—50 billion or more. I also tried another brand from Australia with 50 billion, and the difference is remarkable. Sometimes, if I don’t take it, I struggle to go to the loo, and when I do, it’s a different experience altogether. This one was similar to the 50 billion from the same brand. I don’t notice a large difference between the 50 and 100 billion varieties, but I definitely feel the impact when I skip it. It has certainly aided my constipation and gut troubles. If you don’t have severe issues, even the 20 billion should suffice.
Read More
7.5
Stops diarrhoea effectively
It enhances my bowel function, particularly when I had stomach flu due to a viral fever; it effectively helps to stop the watery diarrhoea.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8
  • All Researches
9
Probiotics improve poultry health
We combined findings from three separate trials to evaluate the effects of a dual-strain probiotic consisting of Lactobacillus acidophilus and Bifidobacterium animalis on broilers facing mild necrotic enteritis.

In these studies, birds receiving the probiotic showed improved growth and feed intake, alongside a reduction in mortality and intestinal lesions compared to untreated controls.

This suggests that probiotics can effectively counter the adverse impacts of necrotic enteritis in poultry, enhancing overall gut health and growth performance.
Read More
We explored how two strains of Lactobacillus, NCFM and Lp-115, can help tackle the pesky H. pylori bacteria that often lead to gastric inflammation.

In a controlled study using mice, we treated groups with these probiotics for six weeks. Results showed that both strains significantly reduced H. pylori adhesion and the inflammation response in stomach tissues.

This suggests that Lactobacillus could be a promising ally in managing the negative effects of gastric infections.
Read More
9
Lactobacillus acidophilus benefits colitis
This study looked into how Lactobacillus acidophilus LA85 impacts ulcerative colitis in mice. We established a mouse model of this condition by using a chemical solution that triggers colitis symptoms.

The results were encouraging: mice treated with L. acidophilus LA85 showed significant improvements, such as less weight loss and reduced colon damage compared to untreated counterparts.

Additionally, this probiotic helped balance gut bacteria and improved inflammation markers, making it a promising option for addressing similar conditions in humans.
Read More
8
LA reduces Salmonella-induced inflammation
We explored the impact of Lactobacillus acidophilus (LA) on inflammation and oxidative stress caused by Salmonella Typhimurium in mice. After treating the mice with LA for 14 days, we observed significant improvements in gut health. LA reduced harmful serum compounds and boosted antioxidant enzyme levels, supporting better recovery.

The study also highlighted how LA regulates gut bacteria, suggesting it could be useful for disease resistance. While the research focused on animal models, it offers promising insights for future solutions in gut health and disease prevention.
Read More
7
Probiotics may reduce diarrhea duration
We explored the impact of Lactobacillus acidophilus and other probiotics on children suffering from acute gastroenteritis. Our systematic review included randomized controlled trials comparing probiotics to placebos, focusing on strains available in Japan.

Although we found that probiotics like Lactobacillus acidophilus might shorten diarrhea duration by roughly one day, the evidence is not very strong.

Overall, while there were some positive signs in our findings, we recommend more research to confirm these effects and improve treatment strategies.
Read More

User Reviews

USERS' SCORE
Good
Based on 3 Reviews
8.4
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Relief from discomfort
1 people found this helpful
After suffering from gastroenteritis for a while, I tried 1000 Probiotics. After 60 days, I experienced no more discomfort in my intestines. This morning, I woke up feeling good. I’m hopeful that my gastrointestinal condition will continue to improve after using it for this duration.
Read More
7.5
Significant gut improvement
2 people found this helpful
Life changing, honestly. When I say life changing, I’m not just referring to this specific product, but to the probiotics my gastro prescribed—50 billion or more. I also tried another brand from Australia with 50 billion, and the difference is remarkable. Sometimes, if I don’t take it, I struggle to go to the loo, and when I do, it’s a different experience altogether. This one was similar to the 50 billion from the same brand. I don’t notice a large difference between the 50 and 100 billion varieties, but I definitely feel the impact when I skip it. It has certainly aided my constipation and gut troubles. If you don’t have severe issues, even the 20 billion should suffice.
Read More
7.5
Stops diarrhoea effectively
It enhances my bowel function, particularly when I had stomach flu due to a viral fever; it effectively helps to stop the watery diarrhoea.
Read More

Frequently Asked Questions

9
Relief from discomfort
1 people found this helpful
After suffering from gastroenteritis for a while, I tried 1000 Probiotics. After 60 days, I experienced no more discomfort in my intestines. This morning, I woke up feeling good. I’m hopeful that my gastrointestinal condition will continue to improve after using it for this duration.
7.5
Stops diarrhoea effectively
It enhances my bowel function, particularly when I had stomach flu due to a viral fever; it effectively helps to stop the watery diarrhoea.
7.5
Significant gut improvement
2 people found this helpful
Life changing, honestly. When I say life changing, I’m not just referring to this specific product, but to the probiotics my gastro prescribed—50 billion or more. I also tried another brand from Australia with 50 billion, and the difference is remarkable. Sometimes, if I don’t take it, I struggle to go to the loo, and when I do, it’s a different experience altogether. This one was similar to the 50 billion from the same brand. I don’t notice a large difference between the 50 and 100 billion varieties, but I definitely feel the impact when I skip it. It has certainly aided my constipation and gut troubles. If you don’t have severe issues, even the 20 billion should suffice.
7
Probiotics may reduce diarrhea duration
We explored the impact of Lactobacillus acidophilus and other probiotics on children suffering from acute gastroenteritis. Our systematic review included randomized controlled trials comparing probiotics to placebos, focusing on strains available in Japan.

Although we found that probiotics like Lactobacillus acidophilus might shorten diarrhea duration by roughly one day, the evidence is not very strong.

Overall, while there were some positive signs in our findings, we recommend more research to confirm these effects and improve treatment strategies.
7
Lactobacillus impact on diarrhea duration
We reviewed multiple databases for studies on using Lactobacillus acidophilus to treat acute gastroenteritis in children. Our analysis incorporated 15 randomized controlled trials with 1,765 young patients.

While Lactobacillus acidophilus appeared to shorten diarrhea duration when used at a daily dose of 10 CFU or more, this finding wasn't statistically significant for single strains. It did show some effectiveness in reducing diarrhea frequency after a few days, primarily on day three.

However, the evidence overall remains moderate to low in quality, suggesting the need for further research.
8
LA reduces Salmonella-induced inflammation
We explored the impact of Lactobacillus acidophilus (LA) on inflammation and oxidative stress caused by Salmonella Typhimurium in mice. After treating the mice with LA for 14 days, we observed significant improvements in gut health. LA reduced harmful serum compounds and boosted antioxidant enzyme levels, supporting better recovery.

The study also highlighted how LA regulates gut bacteria, suggesting it could be useful for disease resistance. While the research focused on animal models, it offers promising insights for future solutions in gut health and disease prevention.

References

  1. Li H, Ma X, Shang Z, Liu X, Qiao J. alleviate Serovar Typhimurium-induced murine inflammatory/oxidative responses via the p62-Keap1-Nrf2 signaling pathway and cecal microbiota. Front Microbiol. 2024;15:1483705. doi:10.3389/fmicb.2024.1483705
  2. van der Klein SAS, Bernardeau M, Wang Q, Gibbs K. A cross-study analysis of the effect of a dual-strain probiotic applied via the waterline on the growth performance and gut health of broilers under a mild necrotic enteritis challenge. Poult Sci. 2025;104:104550. doi:10.1016/j.psj.2024.104550
  3. Higuchi T, Furuichi M, Maeda N, Tsugawa T, Ito K. Effects of probiotics in children with acute gastroenteritis: A systematic review and meta-analysis focusing on probiotics utilized in Japan. J Infect Chemother. 2024;30:337. doi:10.1016/j.jiac.2023.11.005
  4. Shen S, Ren F, Qin H, Bukhari I, Yang J, et al. NCFM and Lp-115 inhibit colonization and gastric inflammation in a murine model. Front Cell Infect Microbiol. 2023;13:1196084. doi:10.3389/fcimb.2023.1196084
  5. Han M, Liao W, Dong Y, Fei T, Gai Z. Sustained ameliorative effect of Lactobacillus acidophilus LA85 on dextran sulfate sodium-induced colitis in mice. J Food Sci. 2023;88:3893. doi:10.1111/1750-3841.16723
  6. Healy DB, Campbell-Green B, Livingstone V, Ryan CA, Ross RP, et al. Neonatal outcomes following introduction of routine probiotic supplementation to very preterm infants. Acta Paediatr. 2023;112:2093. doi:10.1111/apa.16923
  7. Cheng H, Ma Y, Liu X, Tian C, Zhong X, et al. A Systematic Review and Meta-Analysis: for Treating Acute Gastroenteritis in Children. Nutrients. 2022;14. doi:10.3390/nu14030682
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