Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 26 Researches
7
USERS' SCORE
Moderately Good
Based on 9 Reviews
7.4
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Blend of 10 Strains of Probiotic Bacteria: Lactobacillus acidophilus (La-14), Bifidobacterium lactis (Bl-04),Lactobacillus plantarum (Lp-115), Lactobacillus casei (Lc-11),Lactobacillus rhamnosus (Lr-32), Lactobacillus paracasei (Lpc-37),Bifidobacterium breve (Bb-03), Streptococcus thermophilus (St-21),Lactobacillus salivarius (Ls-33), Bifidobacterium longum (BI-05)
100 Billion CFU
*
Top Medical Research Studies
9
We investigated whether a probiotic mix containing Lactobacillus acidophilus could prevent recurrent urinary tract infections (UTIs) in children aged 4 months to 5 years.
The study involved 181 children divided into two groups, one receiving probiotics and the other a placebo, over 18 months.
Results showed that the probiotic group had a lower recurrence of UTIs, with a composite cure rate of 96.7% compared to 83.3% in the placebo group. Overall, using this probiotic mixture may be a promising non-antibiotic option for UTI prevention in young children.
The study involved 181 children divided into two groups, one receiving probiotics and the other a placebo, over 18 months.
Results showed that the probiotic group had a lower recurrence of UTIs, with a composite cure rate of 96.7% compared to 83.3% in the placebo group. Overall, using this probiotic mixture may be a promising non-antibiotic option for UTI prevention in young children.
Read More
8
We explored how well lactobacillus acidophilus and other probiotics can inhibit urinary tract pathogens like E. coli and Enterococcus faecalis. Using specific tests, we found that while all probiotic strains, including L. acidophilus, showed some inhibitory effects, the mixtures of probiotics did not perform better than individual strains. This hints at potential benefits in reducing urinary tract infections, but the advantage of probiotic mixtures remains unclear.
Essentially, these probiotics can help combat urinary infections through their activity, yet further research is needed to determine their practical use.
Essentially, these probiotics can help combat urinary infections through their activity, yet further research is needed to determine their practical use.
Read More
8
We investigated how a biosurfactant called 'surlactin,' derived from Lactobacillus acidophilus, prevents harmful bacteria and yeast from sticking to surfaces that mimic the urinary tract. Using a specialized flow chamber, we observed that surlactin significantly reduced the adhesion of most bacteria tested, particularly effective against common culprits like E. coli and Staphylococcus. Though yeast attachment was also lowered by 50%, their overall numbers remained unchanged. This suggests that while lactobacillus can inhibit some pathogens, it may not be as effective against yeast in the same context.
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Most Useful Reviews
9
Yeast infection relief
9 people found this helpful
This might be a bit sensitive to discuss, but many women, including myself, have experienced girly issues like certain infections. I don't understand why, as I maintain good hygiene. I previously relied on yoghurts, but they took ages to work. Instead, I've switched to probiotic pills to better fight yeast infections, and they’ve worked wonders for me. Within a week, my yeast infection seemed to clear up completely. Since starting these, I haven't faced that issue again. I even noticed that the eczema around my lips has been less irritated. I can't say if that's intentional, but I’m pleased with the results. I would surely repurchase this!
Read More
9
Symptoms improved
2 people found this helpful
Perfect! This probiotic has markedly improved my gastrointestinal health in just a week. Many previous issues have vanished, and I’m excited to continue taking it.
Read More
9
Recovery supported
1 people found this helpful
Perfectly! These capsules have positively impacted my husband's immune system during his course of antibiotics, significantly aiding the recovery of his digestive tract. After taking them during treatment and for a week afterward, his digestive health greatly improved.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 26 Researches
7
- All Researches
9
We investigated whether a probiotic mix containing Lactobacillus acidophilus could prevent recurrent urinary tract infections (UTIs) in children aged 4 months to 5 years.
The study involved 181 children divided into two groups, one receiving probiotics and the other a placebo, over 18 months.
Results showed that the probiotic group had a lower recurrence of UTIs, with a composite cure rate of 96.7% compared to 83.3% in the placebo group. Overall, using this probiotic mixture may be a promising non-antibiotic option for UTI prevention in young children.
The study involved 181 children divided into two groups, one receiving probiotics and the other a placebo, over 18 months.
Results showed that the probiotic group had a lower recurrence of UTIs, with a composite cure rate of 96.7% compared to 83.3% in the placebo group. Overall, using this probiotic mixture may be a promising non-antibiotic option for UTI prevention in young children.
Read More
9
We examined how a combination of D-mannose, Salicin, and Lactobacillus acidophilus could help those suffering from recurrent urinary tract infections caused by E. coli. During our study with 85 participants, we introduced this regimen over several weeks and surveyed symptoms through a bladder diary and a scale measuring pain levels.
The results were promising. Participants experienced notable reductions in pain and frequency of symptoms. However, while our findings indicate this approach could be beneficial, further large-scale studies are necessary to confirm its effectiveness.
The results were promising. Participants experienced notable reductions in pain and frequency of symptoms. However, while our findings indicate this approach could be beneficial, further large-scale studies are necessary to confirm its effectiveness.
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9
We explored how locally isolated Lactobacillus species could tackle antibiotic-resistant bacteria responsible for urinary tract infections. Our study involved screening lactic acid bacteria extracted from spoiled produce against various resistant pathogens.
The results were promising, showing that these lactobacilli had antimicrobial activity against six out of seven tested uropathogens. This suggests that using Lactobacillus may be a viable alternative in the battle against UTIs, helping to combat antibiotic resistance effectively.
The results were promising, showing that these lactobacilli had antimicrobial activity against six out of seven tested uropathogens. This suggests that using Lactobacillus may be a viable alternative in the battle against UTIs, helping to combat antibiotic resistance effectively.
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9
We investigated how by-products from Lactobacillus rhamnosus can affect uropathogenic Escherichia coli (UPEC), the bacteria commonly responsible for urinary tract infections (UTIs). Our findings revealed that lactic acid, hydrogen peroxide, and other compounds from these probiotics significantly inhibited the growth of UPEC.
Additionally, they reduced the production of proteins that help the bacteria cling to the urinary tract. This suggests that Lactobacillus rhamnosus and its by-products offer protective benefits against UTIs by combating harmful bacteria and reducing their ability to establish infections.
Additionally, they reduced the production of proteins that help the bacteria cling to the urinary tract. This suggests that Lactobacillus rhamnosus and its by-products offer protective benefits against UTIs by combating harmful bacteria and reducing their ability to establish infections.
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8
We explored the effectiveness of probiotic lactic acid bacteria, particularly Lactobacillus acidophilus, in preventing urinary tract infections linked to catheters.
Through a thorough study involving 120 catheterized patients, we tested various uropathogens and their ability to form biofilms.
Although probiotics showed promise in preventing catheter colonization in vitro, further research is necessary to confirm safety and efficacy in real-life settings.
This suggests a potential step forward in managing catheter-associated urinary infections.
Through a thorough study involving 120 catheterized patients, we tested various uropathogens and their ability to form biofilms.
Although probiotics showed promise in preventing catheter colonization in vitro, further research is necessary to confirm safety and efficacy in real-life settings.
This suggests a potential step forward in managing catheter-associated urinary infections.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 9 Reviews
7.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Yeast infection relief
9 people found this helpful
This might be a bit sensitive to discuss, but many women, including myself, have experienced girly issues like certain infections. I don't understand why, as I maintain good hygiene. I previously relied on yoghurts, but they took ages to work. Instead, I've switched to probiotic pills to better fight yeast infections, and they’ve worked wonders for me. Within a week, my yeast infection seemed to clear up completely. Since starting these, I haven't faced that issue again. I even noticed that the eczema around my lips has been less irritated. I can't say if that's intentional, but I’m pleased with the results. I would surely repurchase this!
Read More
9
Symptoms improved
2 people found this helpful
Perfect! This probiotic has markedly improved my gastrointestinal health in just a week. Many previous issues have vanished, and I’m excited to continue taking it.
Read More
9
Recovery supported
1 people found this helpful
Perfectly! These capsules have positively impacted my husband's immune system during his course of antibiotics, significantly aiding the recovery of his digestive tract. After taking them during treatment and for a week afterward, his digestive health greatly improved.
Read More
8
Digestive improvement
8 people found this helpful
I bought this probiotic for my children, hoping to enhance their immune systems. I tested these probiotics with sour milk, and it produced a delightful fermented product. While I don't notice any significant effects on my children, these capsules proved invaluable for my husband, who needed antibiotics and injections for 14 days. Since he took these probiotics throughout his treatment and for a week afterward, they effectively saved his digestive tract, restoring balance during that demanding time.
Read More
7.5
Complete relief achieved
2 people found this helpful
Good! I have been taking lactic acid bacteria for my Irritable Bowel Syndrome and Candida vaginitis, and I found this probiotic beneficial. It successfully eliminated my yeast infection symptoms, providing pivotal relief. I had been sceptical, but the positive effects have made me feel settled regarding my health again.
Read More
Frequently Asked Questions
9
Yeast infection relief
9 people found this helpful
This might be a bit sensitive to discuss, but many women, including myself, have experienced girly issues like certain infections. I don't understand why, as I maintain good hygiene. I previously relied on yoghurts, but they took ages to work. Instead, I've switched to probiotic pills to better fight yeast infections, and they’ve worked wonders for me. Within a week, my yeast infection seemed to clear up completely. Since starting these, I haven't faced that issue again. I even noticed that the eczema around my lips has been less irritated. I can't say if that's intentional, but I’m pleased with the results. I would surely repurchase this!
9
Symptoms improved
2 people found this helpful
Perfect! This probiotic has markedly improved my gastrointestinal health in just a week. Many previous issues have vanished, and I’m excited to continue taking it.
9
Recovery supported
1 people found this helpful
Perfectly! These capsules have positively impacted my husband's immune system during his course of antibiotics, significantly aiding the recovery of his digestive tract. After taking them during treatment and for a week afterward, his digestive health greatly improved.
8
Digestive improvement
8 people found this helpful
I bought this probiotic for my children, hoping to enhance their immune systems. I tested these probiotics with sour milk, and it produced a delightful fermented product. While I don't notice any significant effects on my children, these capsules proved invaluable for my husband, who needed antibiotics and injections for 14 days. Since he took these probiotics throughout his treatment and for a week afterward, they effectively saved his digestive tract, restoring balance during that demanding time.
7.5
Gut health restored
2 people found this helpful
I felt no adverse effects. After extensive antibiotic use, restoring my gastrointestinal tract became essential. Two months post-illness, I can eat comfortably again, and my digestion has greatly improved. The quality from this manufacturer is consistently top-notch.
0
Dissatisfaction noted
12 people found this helpful
I experienced no benefit at all. Since childhood, I've frequently used intestinal preparations due to a weak gastrointestinal tract. I loved my previous probiotics, but after switching to this product, my bloating and constipation worsened. Despite similar ingredients, the results were disappointing. I’m purchasing my old probiotics from another source now, as it seems the quality has declined since I-Herb changed ownership. My dissatisfaction is compounded by the limited selection available for Asia.
7.5
Complete relief achieved
2 people found this helpful
Good! I have been taking lactic acid bacteria for my Irritable Bowel Syndrome and Candida vaginitis, and I found this probiotic beneficial. It successfully eliminated my yeast infection symptoms, providing pivotal relief. I had been sceptical, but the positive effects have made me feel settled regarding my health again.
9
We investigated whether a probiotic mix containing Lactobacillus acidophilus could prevent recurrent urinary tract infections (UTIs) in children aged 4 months to 5 years.
The study involved 181 children divided into two groups, one receiving probiotics and the other a placebo, over 18 months.
Results showed that the probiotic group had a lower recurrence of UTIs, with a composite cure rate of 96.7% compared to 83.3% in the placebo group. Overall, using this probiotic mixture may be a promising non-antibiotic option for UTI prevention in young children.
The study involved 181 children divided into two groups, one receiving probiotics and the other a placebo, over 18 months.
Results showed that the probiotic group had a lower recurrence of UTIs, with a composite cure rate of 96.7% compared to 83.3% in the placebo group. Overall, using this probiotic mixture may be a promising non-antibiotic option for UTI prevention in young children.
7
We explored how specific Lactobacillus strains, especially L. acidophilus, can prevent urinary tract infections (UTIs) by testing their effects on harmful bacteria's ability to stick to bladder cells.
The study found that L. acidophilus significantly reduced the adherence of uropathogenic bacteria by up to 53.7%, suggesting its potential role in UTI prevention.
In contrast, another strain, L. plantarum, showed minimal effectiveness. Overall, our findings indicate a promising benefit of Lactobacillus in combating UTIs.
The study found that L. acidophilus significantly reduced the adherence of uropathogenic bacteria by up to 53.7%, suggesting its potential role in UTI prevention.
In contrast, another strain, L. plantarum, showed minimal effectiveness. Overall, our findings indicate a promising benefit of Lactobacillus in combating UTIs.
5
Moderate lactobacillus activity noted
We aimed to explore the potential of lactobacillus probiotics, including L. acidophilus, as an alternative to antibiotic treatments for urinary tract infections (UTIs). By comparing the antibacterial effects of six lactobacillus strains against common uropathogens, we found that these probiotics showed moderate inhibition, with results falling between sensitive and resistant antibiotics.
However, further studies are needed to identify which strains might offer the most effective probiotic benefits. Overall, while promising, lactobacillus strains currently don't surpass traditional antibiotics in their effectiveness against UTIs.
However, further studies are needed to identify which strains might offer the most effective probiotic benefits. Overall, while promising, lactobacillus strains currently don't surpass traditional antibiotics in their effectiveness against UTIs.
References
- Mahgoub MA, Abbass AAG, Abaza AF, Shoukry MS. Probiotic lactic acid bacteria as a means of preventing in vitro urinary catheter colonization and biofilm formation. J Egypt Public Health Assoc. 2023;97:30. 10.1186/s42506-022-00124-2
- Sadeghi-Bojd S, Naghshizadian R, Mazaheri M, Ghane Sharbaf F, Assadi F. Efficacy of Probiotic Prophylaxis After The First Febrile Urinary Tract Infection in Children With Normal Urinary Tracts. J Pediatric Infect Dis Soc. 2020;9:305. 10.1093/jpids/piz025
- Del Popolo G, Nelli F. Recurrent bacterial symptomatic cystitis: A pilot study on a new natural option for treatment. Arch Ital Urol Androl. 2018;90:101. 10.4081/aiua.2018.2.101
- de Llano DG, Arroyo A, Cárdenas N, Rodríguez JM, Moreno-Arribas MV, et al. Strain-specific inhibition of the adherence of uropathogenic bacteria to bladder cells by probiotic Lactobacillus spp. Pathog Dis. 2017;75. 10.1093/femspd/ftx043
- Shim YH, Lee SJ, Lee JW. Antimicrobial activity of lactobacillus strains against uropathogens. Pediatr Int. 2016;58:1009. 10.1111/ped.12949
- Manzoor A, Ul-Haq I, Baig S, Qazi JI, Seratlic S. Efficacy of Locally Isolated Lactic Acid Bacteria Against Antibiotic-Resistant Uropathogens. Jundishapur J Microbiol. 2016;9:e18952. 10.5812/jjm.18952
- Lee SJ, Lee JW. Probiotics prophylaxis in infants with primary vesicoureteral reflux. Pediatr Nephrol. 2015;30:609. 10.1007/s00467-014-2988-z
- Rodrigues F, Maia MJ, das Neves J, Sarmento B, Amaral MH, et al. Vaginal suppositories containing Lactobacillus acidophilus: development and characterization. Drug Dev Ind Pharm. 2015;41:1518. 10.3109/03639045.2014.963864
- Mohseni MJ, Aryan Z, Emamzadeh-Fard S, Paydary K, Mofid V, et al. Combination of probiotics and antibiotics in the prevention of recurrent urinary tract infection in children. Iran J Pediatr. 2013;23:430.
- Chapman CM, Gibson GR, Todd S, Rowland I. Comparative in vitro inhibition of urinary tract pathogens by single- and multi-strain probiotics. Eur J Nutr. 2013;52:1669. 10.1007/s00394-013-0501-2
- Lee SJ, Shim YH, Cho SJ, Lee JW. Probiotics prophylaxis in children with persistent primary vesicoureteral reflux. Pediatr Nephrol. 2007;22:1315.
- Juárez Tomás MS, Ocaña VS, Wiese B, Nader-Macías ME. Growth and lactic acid production by vaginal Lactobacillus acidophilus CRL 1259, and inhibition of uropathogenic Escherichia coli. J Med Microbiol. 2003;52:1117. 10.1099/jmm.0.05155-0
- Velraeds MM, van de Belt-Gritter B, van der Mei HC, Reid G, Busscher HJ. Interference in initial adhesion of uropathogenic bacteria and yeasts to silicone rubber by a Lactobacillus acidophilus biosurfactant. J Med Microbiol. 1998;47:1081.
- Reid G, Bruce AW, McGroarty JA, Cheng KJ, Costerton JW. Is there a role for lactobacilli in prevention of urogenital and intestinal infections?. Clin Microbiol Rev. 1990;3:335.
- Kyser AJ, Greiner A, Harris V, Patel R, Frieboes HB, et al. 3D-Bioprinted Urinary Catheters Enable Sustained Probiotic Recovery Under Flow and Improve Bladder Colonization In Vivo. Probiotics Antimicrob Proteins. 2025. 10.1007/s12602-024-10428-8
- Ghane M, Babaeekhou L, Ketabi SS. Antibiofilm Activity of Kefir Probiotic Lactobacilli Against Uropathogenic (UPEC). Avicenna J Med Biotechnol. 2020;12:221.
- Toh SL, Lee BB, Ryan S, Simpson JM, Clezy K, et al. Probiotics [LGG-BB12 or RC14-GR1] versus placebo as prophylaxis for urinary tract infection in persons with spinal cord injury [ProSCIUTTU]: a randomised controlled trial. Spinal Cord. 2019;57:550. 10.1038/s41393-019-0251-y
- Kara SS, Volkan B, Erten I. GG can protect malnourished children. Benef Microbes. 2019;10:237. 10.3920/BM2018.0071
- Ng QX, Peters C, Venkatanarayanan N, Goh YY, Ho CYX, et al. Use of Lactobacillus spp. to prevent recurrent urinary tract infections in females. Med Hypotheses. 2018;114:49. 10.1016/j.mehy.2018.03.001
- Montorsi F, Gandaglia G, Salonia A, Briganti A, Mirone V. Effectiveness of a Combination of Cranberries, Lactobacillus rhamnosus, and Vitamin C for the Management of Recurrent Urinary Tract Infections in Women: Results of a Pilot Study. Eur Urol. 2016;70:912. 10.1016/j.eururo.2016.05.042
- Lee JW, Lee JH, Sung SH, Lee SJ. Preventive effects of Lactobacillus mixture on experimental E. coli urinary tract infection in infant rats. Yonsei Med J. 2013;54:489. 10.3349/ymj.2013.54.2.489
- Beerepoot MA, ter Riet G, Nys S, van der Wal WM, de Borgie CA, et al. Lactobacilli vs antibiotics to prevent urinary tract infections: a randomized, double-blind, noninferiority trial in postmenopausal women. Arch Intern Med. 2012;172:704. 10.1001/archinternmed.2012.777
- Karlsson M, Scherbak N, Khalaf H, Olsson PE, Jass J. Substances released from probiotic Lactobacillus rhamnosus GR-1 potentiate NF-κB activity in Escherichia coli-stimulated urinary bladder cells. FEMS Immunol Med Microbiol. 2012;66:147. 10.1111/j.1574-695X.2012.00994.x
- Cadieux PA, Burton J, Devillard E, Reid G. Lactobacillus by-products inhibit the growth and virulence of uropathogenic Escherichia coli. J Physiol Pharmacol. 2009;60 Suppl 6:13.
- Anukam KC, Hayes K, Summers K, Reid G. Probiotic Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14 may help downregulate TNF-Alpha, IL-6, IL-8, IL-10 and IL-12 (p70) in the neurogenic bladder of spinal cord injured patient with urinary tract infections: a two-case study. Adv Urol. 2009;2009:680363. 10.1155/2009/680363
- Falagas ME, Betsi GI, Tokas T, Athanasiou S. Probiotics for prevention of recurrent urinary tract infections in women: a review of the evidence from microbiological and clinical studies. Drugs. 2006;66:1253.
