We explored the potential of dermcidin, a natural antimicrobial protein, in fighting off Trichophyton rubrum, the fungus responsible for athlete’s foot. Our research involved testing recombinant dermcidin to evaluate its ability to inhibit the growth of this fungus. The results were quite promising, revealing that at typical sweat levels of dermcidin—about 50 μg/mL—it was able to reduce fungal growth by 40.5%. When we ramped up the concentration to 270 μg/mL, the effect amplified significantly, with a 93.4% reduction in fungal presence.
Further analysis showed that dermcidin not only kills Trichophyton but also impacts its metabolic activity, making it less effective at thriving on the skin. Interestingly, we found that individuals suffering from tinea pedis, commonly known as athlete’s foot, had lower levels of dermcidin in their sweat compared to healthy individuals. This suggests that sufficient levels of dermcidin are critical in protecting our skin against fungal infections.
Ultimately, this study highlights dermcidin's important role in skin health, particularly its potential to prevent athlete’s foot by inhibiting the growth of the fungus. It seems that maintaining adequate levels of this protein might be key to successfully combating these infections and supporting overall skin immunity.
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Most Useful Reviews
7.5
Improved skin softness
5 people found this helpful
I add this wheat germ oil to my daily salad rather than using olive oil, appreciating its almond flavour. The oil is additive-free and contains naturally occurring vitamin E, and is also non-GMO. I favour this brand and frequently purchase their products. Within a few days, I noticed a difference in my skin; it feels noticeably softer, and my soles feel great. I also give it to my dog by adding it directly to his food bowl.
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7.5
Soothing skin treatment
5 people found this helpful
The quality is exceptional, with natural ingredients suitable for all ages. The box is well-filled, providing enough product for months. The benefits include soothing and brightening the skin, particularly the soles of the feet. The hair conditioner is moisturising and effectively addresses inflammation. It even helps with ceramic burns, although it does have a slight unpleasant odour.
We explored the potential of dermcidin, a natural antimicrobial protein, in fighting off Trichophyton rubrum, the fungus responsible for athlete’s foot. Our research involved testing recombinant dermcidin to evaluate its ability to inhibit the growth of this fungus. The results were quite promising, revealing that at typical sweat levels of dermcidin—about 50 μg/mL—it was able to reduce fungal growth by 40.5%. When we ramped up the concentration to 270 μg/mL, the effect amplified significantly, with a 93.4% reduction in fungal presence.
Further analysis showed that dermcidin not only kills Trichophyton but also impacts its metabolic activity, making it less effective at thriving on the skin. Interestingly, we found that individuals suffering from tinea pedis, commonly known as athlete’s foot, had lower levels of dermcidin in their sweat compared to healthy individuals. This suggests that sufficient levels of dermcidin are critical in protecting our skin against fungal infections.
Ultimately, this study highlights dermcidin's important role in skin health, particularly its potential to prevent athlete’s foot by inhibiting the growth of the fungus. It seems that maintaining adequate levels of this protein might be key to successfully combating these infections and supporting overall skin immunity.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.3
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Negative Reviews
7.5
Improved skin softness
5 people found this helpful
I add this wheat germ oil to my daily salad rather than using olive oil, appreciating its almond flavour. The oil is additive-free and contains naturally occurring vitamin E, and is also non-GMO. I favour this brand and frequently purchase their products. Within a few days, I noticed a difference in my skin; it feels noticeably softer, and my soles feel great. I also give it to my dog by adding it directly to his food bowl.
Read More
7.5
Soothing skin treatment
5 people found this helpful
The quality is exceptional, with natural ingredients suitable for all ages. The box is well-filled, providing enough product for months. The benefits include soothing and brightening the skin, particularly the soles of the feet. The hair conditioner is moisturising and effectively addresses inflammation. It even helps with ceramic burns, although it does have a slight unpleasant odour.
Read More
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References
Arai S, Yoshino T, Fujimura T, Maruyama S, Nakano T, et al. Mycostatic effect of recombinant dermcidin against Trichophyton rubrum and reduced dermcidin expression in the sweat of tinea pedis patients. J Dermatol. 2015;42:70. 10.1111/1346-8138.12664