My hubby has had high cholesterol and been on meds for at least 5 years. They gave him terrible Leg cramps, increased the muscle enzymes in his legs to an alarming rate. His doc switched him from one expensive side effect laden statin to another. I started him on the Choleast 900 and Omegagenics EPA-DHA 500, along with a reduction in some bad for you food (fat and carbs) and increase in some good for you food (greens, veggies) and some walking. I'm not talking an overhaul in diet at all, just some small changes. He is within normal limits for the first time in years and his doctor was shocked at the change in the last six months...and that it was without the drugs. I can't recommend these supplements highly enough. No more Leg cramps for him, no more outrageous prescription costs for us, no more supporting big pharma, and most importantly, no more high cholesterol! Now they just need an auto deliver program cuz he's all over me when he runs out and I forget to order more ;