'
Thorne Ultimate-E
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.4
USERS' SCORE
Good
Based on 1 Review
8.6
Supplement Facts
Serving Size:  One Gelcap
Amount Per Serving
%DV
Vitamin E (as d-Alpha Tocopherol from 1,000 mg Mixed Tocopherols) 
335 mg
2,233%

Top Medical Research Studies

9
Vitamin E may reduce blood clots
Effects of random allocation to vitamin E supplementation on the occurrence of venous thromboembolism: report from the Women's Health Study.
High relevance to VTE treatment
We investigated whether vitamin E supplementation affects the risk of blood clots, specifically venous thromboembolism (VTE), in women. The Women's Health Study involved nearly 40,000 women who received either vitamin E or a placebo over more than ten years.

Our findings revealed that those taking vitamin E experienced a significant reduction in VTE occurrences compared to the placebo group. Notably, women with a history of VTE or certain genetic factors benefited the most from supplementation.

Overall, vitamin E may play a protective role against blood clots, offering promise for at-risk individuals.
Read More
9
Vitamin E aids blood clot resolution
Vitamin E improves fibrinolytic activity in patients with coronary spastic angina.
Significant results within study scope
We explored how vitamin E affects blood clot breakdown in patients suffering from coronary spastic angina. In a well-structured study, 40 participants were split into groups receiving either vitamin E or a placebo over a month.

We observed that those who took vitamin E experienced significant improvements, with decreased levels of a key clotting factor and a marker for oxidative stress. This suggests that vitamin E may serve as an effective addition to treatments for managing coronary spasms, especially in patients without coronary atherosclerosis.
Read More
8
HO-1 induction delays blood clotting
Vascular heme oxygenase-1 induction suppresses microvascular thrombus formation in vivo.
Study shows potential therapeutic benefits
We explored how inducing heme oxygenase-1 (HO-1) could impact blood clot formation in a mouse model. Through a series of tests, we observed that mice treated with a HO-1 inducer showed a significant delay in thrombus formation.

This effect was linked to the production of bilirubin and carbon monoxide, which have protective roles in the bloodstream. Interestingly, when we used a vitamin E analogue, it almost entirely restored this delay in clotting. Overall, these findings suggest that enhancing HO-1 activity may offer a promising approach to prevent undesirable blood clots.
Read More

Most Useful Reviews

9.5
Blood thinning effect
This is one of the few Vitamin E products not derived from vegetable oil, specifically soy, which I find detrimental. I take Vitamin E to help thin my blood, particularly as I'm sedentary and wish to avoid blood clots. It works remarkably well for this!
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.4
  • All Researches
9
Tocotrienols reduce blood clot formation
Tocotrienols-induced inhibition of platelet thrombus formation and platelet aggregation in stenosed canine coronary arteries.
Highly relevant for cardiovascular health
Our exploration focused on how tocotrienols, a form of vitamin E, influence blood clotting, especially in the context of risk factors like stroke. Using a canine model, we assessed the effects of tocotrienols on platelet aggregation and thrombus formation.

The findings revealed that tocotrienols significantly inhibited both platelet thrombus formation and collagen-induced platelet aggregation. We noticed that tocotrienols could be converted to tocopherols, which might add to their effectiveness. Overall, these results suggest tocotrienols could offer a therapeutic advantage in preventing serious cardiovascular events.
Read More
9
Vitamin E may reduce blood clots
Effects of random allocation to vitamin E supplementation on the occurrence of venous thromboembolism: report from the Women's Health Study.
High relevance to VTE treatment
We investigated whether vitamin E supplementation affects the risk of blood clots, specifically venous thromboembolism (VTE), in women. The Women's Health Study involved nearly 40,000 women who received either vitamin E or a placebo over more than ten years.

Our findings revealed that those taking vitamin E experienced a significant reduction in VTE occurrences compared to the placebo group. Notably, women with a history of VTE or certain genetic factors benefited the most from supplementation.

Overall, vitamin E may play a protective role against blood clots, offering promise for at-risk individuals.
Read More
9
Vitamin E shows limited blood clot impact
Effects of vitamin E and sesamin on hypertension and cerebral thrombogenesis in stroke-prone spontaneously hypertensive rats.
Preliminary findings on efficacy
We explored the effects of vitamin E and sesamin on blood pressure and blood clot formation using young rats prone to stroke. The rats were divided into four groups: a control group, a vitamin E group, a sesamin group, and a combination group for five weeks.

Notably, the rats receiving vitamin E and sesamin showed lower blood pressure and thrombotic tendencies compared to the control group. However, while there was some reduction in clot formation, it was not substantial enough to conclude a significant clinical benefit.

Thus, we observed that while vitamin E and sesamin may have some protective effects, their impact on blood clot prevention is not definitively established.
Read More
9
Vitamin E aids blood clot resolution
Vitamin E improves fibrinolytic activity in patients with coronary spastic angina.
Significant results within study scope
We explored how vitamin E affects blood clot breakdown in patients suffering from coronary spastic angina. In a well-structured study, 40 participants were split into groups receiving either vitamin E or a placebo over a month.

We observed that those who took vitamin E experienced significant improvements, with decreased levels of a key clotting factor and a marker for oxidative stress. This suggests that vitamin E may serve as an effective addition to treatments for managing coronary spasms, especially in patients without coronary atherosclerosis.
Read More
8
HO-1 induction delays blood clotting
Vascular heme oxygenase-1 induction suppresses microvascular thrombus formation in vivo.
Study shows potential therapeutic benefits
We explored how inducing heme oxygenase-1 (HO-1) could impact blood clot formation in a mouse model. Through a series of tests, we observed that mice treated with a HO-1 inducer showed a significant delay in thrombus formation.

This effect was linked to the production of bilirubin and carbon monoxide, which have protective roles in the bloodstream. Interestingly, when we used a vitamin E analogue, it almost entirely restored this delay in clotting. Overall, these findings suggest that enhancing HO-1 activity may offer a promising approach to prevent undesirable blood clots.
Read More

User Reviews

USERS' SCORE
Good
Based on 1 Review
8.6
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
Blood thinning effect
This is one of the few Vitamin E products not derived from vegetable oil, specifically soy, which I find detrimental. I take Vitamin E to help thin my blood, particularly as I'm sedentary and wish to avoid blood clots. It works remarkably well for this!
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