5/10/2025
Last update
5/10/2025
Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7.6
USERS' SCORE
Good
Based on 3 Reviews
8.4
Supplement Facts
Serving Size: One Gelcap
Amount Per Serving
%DV
Vitamin E (as d-Alpha Tocopherol from 1,000 mg Mixed Tocopherols)
335 mg
2,233%
Top Medical Research Studies
9
Vitamin E alleviates menstrual migraines
We investigated whether vitamin E could help women suffering from menstrual migraines. In a placebo-controlled trial, 72 participants received either a placebo or vitamin E for two cycles, with symptoms recorded monthly.
The results were noteworthy—vitamin E significantly reduced headache severity and related symptoms compared to the placebo. Women reported improvements in pain intensity and functional disability, showing vitamin E's potential as an effective treatment for menstrual migraines.
The results were noteworthy—vitamin E significantly reduced headache severity and related symptoms compared to the placebo. Women reported improvements in pain intensity and functional disability, showing vitamin E's potential as an effective treatment for menstrual migraines.
Read More
7
We explored how menopause affects headaches and the potential role of vitamin E in managing these symptoms. Among various treatment options, vitamin E emerged as one non-medication strategy that might help alleviate headaches related to hormonal changes during menopause. However, while some non-drug approaches like acupuncture and exercise show promise, there is limited evidence supporting the effectiveness of vitamin E specifically. We found that headaches can vary in frequency and severity during menopause, with many women experiencing little change in their headache status.
Read More
7
Vitamin E's mixed effects on headaches
We aimed to understand how vitamin E influences headaches in relation to oxidative stress and calcium levels. Our exploration involved the use of glyceryl trinitrate to induce migraine-like symptoms in experimental models.
We found that both riboflavin and vitamin E helped reduce oxidative stress and supported brain health. While vitamin E showed a significant protective effect against headache mechanisms, it did not provide a clear, standout benefit over riboflavin.
Overall, our findings suggest that vitamin E can play a role in tackling the challenges associated with headaches, but it may not be the sole solution.
We found that both riboflavin and vitamin E helped reduce oxidative stress and supported brain health. While vitamin E showed a significant protective effect against headache mechanisms, it did not provide a clear, standout benefit over riboflavin.
Overall, our findings suggest that vitamin E can play a role in tackling the challenges associated with headaches, but it may not be the sole solution.
Read More
Most Useful Reviews
9
No more headaches
123 people found this helpful
I take this on an empty stomach with my thyroid medication and have drastically reduced the dosage needed. Other brands caused me severe headaches, but this one does not contain soy, making it very effective and highly recommendable.
Read More
0
Causes headaches
1 people found this helpful
The gels are enormous, and each time I take them, I develop a headache soon after. The recommended dose is one to three gels per day, which means a bottle lasts about a month. For more Vitamin E, I suggest consuming more nuts, seeds, and olive oil.
Read More
0
Nausea and headache
2 people found this helpful
Helps with skin and is good quality. I started by taking one pill a day for several days before increasing to two. However, two pills caused nausea and headaches, so I reverted to one pill daily. The pills are quite large.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7.6
- All Researches
9
Vitamin E alleviates menstrual migraines
We investigated whether vitamin E could help women suffering from menstrual migraines. In a placebo-controlled trial, 72 participants received either a placebo or vitamin E for two cycles, with symptoms recorded monthly.
The results were noteworthy—vitamin E significantly reduced headache severity and related symptoms compared to the placebo. Women reported improvements in pain intensity and functional disability, showing vitamin E's potential as an effective treatment for menstrual migraines.
The results were noteworthy—vitamin E significantly reduced headache severity and related symptoms compared to the placebo. Women reported improvements in pain intensity and functional disability, showing vitamin E's potential as an effective treatment for menstrual migraines.
Read More
8
Vitamin E shows potential for migraines
We conducted a randomized, double-blind, sham-controlled pilot study to explore the effects of a combined antioxidant treatment—N-acetylcysteine, vitamin E, and vitamin C—on headaches in adults suffering from migraines.
After three months of treatment, we observed a significant reduction in monthly headaches for the antioxidant group compared to those receiving a sham treatment. Notably, there was a drop in average migraine days, headache intensity, and medication use among those on the antioxidant regimen.
However, while results are promising, further research with more participants is needed to confirm these findings.
After three months of treatment, we observed a significant reduction in monthly headaches for the antioxidant group compared to those receiving a sham treatment. Notably, there was a drop in average migraine days, headache intensity, and medication use among those on the antioxidant regimen.
However, while results are promising, further research with more participants is needed to confirm these findings.
Read More
7
We explored how menopause affects headaches and the potential role of vitamin E in managing these symptoms. Among various treatment options, vitamin E emerged as one non-medication strategy that might help alleviate headaches related to hormonal changes during menopause. However, while some non-drug approaches like acupuncture and exercise show promise, there is limited evidence supporting the effectiveness of vitamin E specifically. We found that headaches can vary in frequency and severity during menopause, with many women experiencing little change in their headache status.
Read More
7
Vitamin E's mixed effects on headaches
We aimed to understand how vitamin E influences headaches in relation to oxidative stress and calcium levels. Our exploration involved the use of glyceryl trinitrate to induce migraine-like symptoms in experimental models.
We found that both riboflavin and vitamin E helped reduce oxidative stress and supported brain health. While vitamin E showed a significant protective effect against headache mechanisms, it did not provide a clear, standout benefit over riboflavin.
Overall, our findings suggest that vitamin E can play a role in tackling the challenges associated with headaches, but it may not be the sole solution.
We found that both riboflavin and vitamin E helped reduce oxidative stress and supported brain health. While vitamin E showed a significant protective effect against headache mechanisms, it did not provide a clear, standout benefit over riboflavin.
Overall, our findings suggest that vitamin E can play a role in tackling the challenges associated with headaches, but it may not be the sole solution.
Read More
7
We explored the effectiveness of a supplement combining pine bark extract and antioxidants, including vitamin E, for patients suffering from migraines that didn't respond to traditional medications.
In a small group of twelve participants, we saw potential improvements in headache frequency and severity after a three-month treatment period. Patients took capsules containing this antioxidant formulation while continuing their usual medications.
While the results are promising, further studies are required to fully assess the benefits of these antioxidants in migraine management.
In a small group of twelve participants, we saw potential improvements in headache frequency and severity after a three-month treatment period. Patients took capsules containing this antioxidant formulation while continuing their usual medications.
While the results are promising, further studies are required to fully assess the benefits of these antioxidants in migraine management.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
No more headaches
123 people found this helpful
I take this on an empty stomach with my thyroid medication and have drastically reduced the dosage needed. Other brands caused me severe headaches, but this one does not contain soy, making it very effective and highly recommendable.
Read More
0
Causes headaches
1 people found this helpful
The gels are enormous, and each time I take them, I develop a headache soon after. The recommended dose is one to three gels per day, which means a bottle lasts about a month. For more Vitamin E, I suggest consuming more nuts, seeds, and olive oil.
Read More
0
Nausea and headache
2 people found this helpful
Helps with skin and is good quality. I started by taking one pill a day for several days before increasing to two. However, two pills caused nausea and headaches, so I reverted to one pill daily. The pills are quite large.
Read More
Frequently Asked Questions
0
Causes headaches
1 people found this helpful
The gels are enormous, and each time I take them, I develop a headache soon after. The recommended dose is one to three gels per day, which means a bottle lasts about a month. For more Vitamin E, I suggest consuming more nuts, seeds, and olive oil.
0
Nausea and headache
2 people found this helpful
Helps with skin and is good quality. I started by taking one pill a day for several days before increasing to two. However, two pills caused nausea and headaches, so I reverted to one pill daily. The pills are quite large.
8
Vitamin E shows potential for migraines
We conducted a randomized, double-blind, sham-controlled pilot study to explore the effects of a combined antioxidant treatment—N-acetylcysteine, vitamin E, and vitamin C—on headaches in adults suffering from migraines.
After three months of treatment, we observed a significant reduction in monthly headaches for the antioxidant group compared to those receiving a sham treatment. Notably, there was a drop in average migraine days, headache intensity, and medication use among those on the antioxidant regimen.
However, while results are promising, further research with more participants is needed to confirm these findings.
After three months of treatment, we observed a significant reduction in monthly headaches for the antioxidant group compared to those receiving a sham treatment. Notably, there was a drop in average migraine days, headache intensity, and medication use among those on the antioxidant regimen.
However, while results are promising, further research with more participants is needed to confirm these findings.
9
Vitamin E alleviates menstrual migraines
We investigated whether vitamin E could help women suffering from menstrual migraines. In a placebo-controlled trial, 72 participants received either a placebo or vitamin E for two cycles, with symptoms recorded monthly.
The results were noteworthy—vitamin E significantly reduced headache severity and related symptoms compared to the placebo. Women reported improvements in pain intensity and functional disability, showing vitamin E's potential as an effective treatment for menstrual migraines.
The results were noteworthy—vitamin E significantly reduced headache severity and related symptoms compared to the placebo. Women reported improvements in pain intensity and functional disability, showing vitamin E's potential as an effective treatment for menstrual migraines.
7
We explored how menopause affects headaches and the potential role of vitamin E in managing these symptoms. Among various treatment options, vitamin E emerged as one non-medication strategy that might help alleviate headaches related to hormonal changes during menopause. However, while some non-drug approaches like acupuncture and exercise show promise, there is limited evidence supporting the effectiveness of vitamin E specifically. We found that headaches can vary in frequency and severity during menopause, with many women experiencing little change in their headache status.
7
Vitamin E's mixed effects on headaches
We aimed to understand how vitamin E influences headaches in relation to oxidative stress and calcium levels. Our exploration involved the use of glyceryl trinitrate to induce migraine-like symptoms in experimental models.
We found that both riboflavin and vitamin E helped reduce oxidative stress and supported brain health. While vitamin E showed a significant protective effect against headache mechanisms, it did not provide a clear, standout benefit over riboflavin.
Overall, our findings suggest that vitamin E can play a role in tackling the challenges associated with headaches, but it may not be the sole solution.
We found that both riboflavin and vitamin E helped reduce oxidative stress and supported brain health. While vitamin E showed a significant protective effect against headache mechanisms, it did not provide a clear, standout benefit over riboflavin.
Overall, our findings suggest that vitamin E can play a role in tackling the challenges associated with headaches, but it may not be the sole solution.
References
- Visser EJ, Drummond PD, Lee-Visser JLA. Reduction in Migraine and Headache Frequency and Intensity With Combined Antioxidant Prophylaxis (N-acetylcysteine, Vitamin E, and Vitamin C): A Randomized Sham-Controlled Pilot Study. Pain Pract. 2020;20:737. 10.1111/papr.12902
- Lauritsen CG, Chua AL, Nahas SJ. Current Treatment Options: Headache Related to Menopause-Diagnosis and Management. Curr Treat Options Neurol. 2018;20:7. 10.1007/s11940-018-0492-7
- Bütün A, Nazıroğlu M, Demirci S, Çelik Ö, Uğuz AC. Riboflavin and vitamin E increase brain calcium and antioxidants, and microsomal calcium-ATP-ase values in rat headache models induced by glyceryl trinitrate. J Membr Biol. 2015;248:205. 10.1007/s00232-014-9758-5
- Ziaei S, Kazemnejad A, Sedighi A. The effect of vitamin E on the treatment of menstrual migraine. Med Sci Monit. 2009;15:CR16.
- Chayasirisobhon S. Use of a pine bark extract and antioxidant vitamin combination product as therapy for migraine in patients refractory to pharmacologic medication. Headache. 2006;46:788.
