SCIENTIFIC SCORE
Possibly Effective
Based on 14 Researches
7.9
USERS' SCORE
Good
Based on 1 Review
8.5
Supplement Facts
Serving Size: One Gelcap
Amount Per Serving
%DV
Vitamin E (as d-Alpha Tocopherol from 1,000 mg Mixed Tocopherols)
335 mg
2,233%
Top Medical Research Studies
9
Vitamin E shows promise for MASH
Vitamin E (300 mg) in the treatment of MASH: A multi-center, randomized, double-blind, placebo-controlled study.
High relevance to liver disease
We investigated the effects of a daily dose of 300 mg vitamin E for treating metabolic dysfunction-associated steatohepatitis (MASH). In our study, 124 non-diabetic individuals were randomly assigned to either vitamin E or a placebo.
The results showed that 29.3% of those on vitamin E had improvements in liver histology, compared to just 14.1% in the placebo group. While we saw significant benefits in liver conditions like steatosis and inflammation, 12 serious adverse events were reported, although they weren’t linked to the treatment.
Overall, our findings indicate that vitamin E may offer meaningful improvements in liver health for those with MASH.
The results showed that 29.3% of those on vitamin E had improvements in liver histology, compared to just 14.1% in the placebo group. While we saw significant benefits in liver conditions like steatosis and inflammation, 12 serious adverse events were reported, although they weren’t linked to the treatment.
Overall, our findings indicate that vitamin E may offer meaningful improvements in liver health for those with MASH.
Read More
9
Vitamin E improves liver markers
Vitamin E improves serum markers and histology in adults with metabolic dysfunction-associated steatotic liver disease: Systematic review and meta-analysis.
Relevant for liver disease research
We analyzed multiple clinical trials to understand how vitamin E impacts liver disease, specifically metabolic dysfunction-associated steatotic liver disease (MASLD).
Our findings reveal that vitamin E significantly improves key liver markers like alanine aminotransferase (ALT) and aspartate aminotransferase (AST), suggesting it may help reduce liver inflammation.
Additionally, vitamin E enhances liver histology by decreasing fat accumulation and inflammation. However, it does not appear to affect liver fibrosis.
Overall, vitamin E could be a valuable option for managing liver health in MASLD patients.
Our findings reveal that vitamin E significantly improves key liver markers like alanine aminotransferase (ALT) and aspartate aminotransferase (AST), suggesting it may help reduce liver inflammation.
Additionally, vitamin E enhances liver histology by decreasing fat accumulation and inflammation. However, it does not appear to affect liver fibrosis.
Overall, vitamin E could be a valuable option for managing liver health in MASLD patients.
Read More
9
Vitamin E improves liver health
A 6-month randomized controlled trial for vitamin E supplementation in pediatric patients with Gaucher disease: Effect on oxidative stress, disease severity and hepatic complications.
Highly relevant study findings
We examined how vitamin E supplementation affects liver disease in children with Gaucher disease. In this clinical trial, 40 pediatric patients receiving enzyme replacement therapy were divided into two groups: one received vitamin E for six months and the other did not.
The results showed that vitamin E significantly reduced oxidative stress markers and improved liver health, as indicated by decreases in liver and spleen volumes and stiffness. This suggests that vitamin E can enhance treatment efficacy for Gaucher disease, making it a safe and beneficial addition to existing therapies.
The results showed that vitamin E significantly reduced oxidative stress markers and improved liver health, as indicated by decreases in liver and spleen volumes and stiffness. This suggests that vitamin E can enhance treatment efficacy for Gaucher disease, making it a safe and beneficial addition to existing therapies.
Read More
Most Useful Reviews
8.8
Liver protection benefits
I acquired this for pre-alcohol consumption. I've trusted Thorne for years, knowing they have in-house labs for testing. I recently heard a Huberman Lab podcast explaining how taking vitamin E before or shortly after alcohol can mitigate the negative impacts on our liver, so I'm giving it a try!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 14 Researches
7.9
- All Researches
9
Vitamin E shows promise for MASH
Vitamin E (300 mg) in the treatment of MASH: A multi-center, randomized, double-blind, placebo-controlled study.
High relevance to liver disease
We investigated the effects of a daily dose of 300 mg vitamin E for treating metabolic dysfunction-associated steatohepatitis (MASH). In our study, 124 non-diabetic individuals were randomly assigned to either vitamin E or a placebo.
The results showed that 29.3% of those on vitamin E had improvements in liver histology, compared to just 14.1% in the placebo group. While we saw significant benefits in liver conditions like steatosis and inflammation, 12 serious adverse events were reported, although they weren’t linked to the treatment.
Overall, our findings indicate that vitamin E may offer meaningful improvements in liver health for those with MASH.
The results showed that 29.3% of those on vitamin E had improvements in liver histology, compared to just 14.1% in the placebo group. While we saw significant benefits in liver conditions like steatosis and inflammation, 12 serious adverse events were reported, although they weren’t linked to the treatment.
Overall, our findings indicate that vitamin E may offer meaningful improvements in liver health for those with MASH.
Read More
9
Vitamin E improves liver health
A 6-month randomized controlled trial for vitamin E supplementation in pediatric patients with Gaucher disease: Effect on oxidative stress, disease severity and hepatic complications.
Highly relevant study findings
We examined how vitamin E supplementation affects liver disease in children with Gaucher disease. In this clinical trial, 40 pediatric patients receiving enzyme replacement therapy were divided into two groups: one received vitamin E for six months and the other did not.
The results showed that vitamin E significantly reduced oxidative stress markers and improved liver health, as indicated by decreases in liver and spleen volumes and stiffness. This suggests that vitamin E can enhance treatment efficacy for Gaucher disease, making it a safe and beneficial addition to existing therapies.
The results showed that vitamin E significantly reduced oxidative stress markers and improved liver health, as indicated by decreases in liver and spleen volumes and stiffness. This suggests that vitamin E can enhance treatment efficacy for Gaucher disease, making it a safe and beneficial addition to existing therapies.
Read More
9
Vitamin E improves liver markers
Vitamin E improves serum markers and histology in adults with metabolic dysfunction-associated steatotic liver disease: Systematic review and meta-analysis.
Relevant for liver disease research
We analyzed multiple clinical trials to understand how vitamin E impacts liver disease, specifically metabolic dysfunction-associated steatotic liver disease (MASLD).
Our findings reveal that vitamin E significantly improves key liver markers like alanine aminotransferase (ALT) and aspartate aminotransferase (AST), suggesting it may help reduce liver inflammation.
Additionally, vitamin E enhances liver histology by decreasing fat accumulation and inflammation. However, it does not appear to affect liver fibrosis.
Overall, vitamin E could be a valuable option for managing liver health in MASLD patients.
Our findings reveal that vitamin E significantly improves key liver markers like alanine aminotransferase (ALT) and aspartate aminotransferase (AST), suggesting it may help reduce liver inflammation.
Additionally, vitamin E enhances liver histology by decreasing fat accumulation and inflammation. However, it does not appear to affect liver fibrosis.
Overall, vitamin E could be a valuable option for managing liver health in MASLD patients.
Read More
9
Gamma-tocotrienol inhibits liver cancer cells
Gamma-tocotrienol Inhibits Proliferation and Growth of HSD17B4 Overexpressing HepG2 Liver Cancer Cells.
High relevance for liver cancer research
We investigated how gamma-tocotrienol (γ-T3), a form of vitamin E, impacts the growth of liver cancer cells. Our study involved treating HepG2 cells, which overexpress a specific protein (HSD17B4), with vitamin E and watching how it changes their behavior.
We found that γ-T3 not only slowed down cell growth but also promoted cell death in these problematic liver cells. Importantly, the effect was not due to changing HSD17B4 expression directly, but by inhibiting its activity instead.
Overall, our results suggest that γ-T3 could be a promising treatment option for liver cancer, especially in targeting cancer growth pathways.
We found that γ-T3 not only slowed down cell growth but also promoted cell death in these problematic liver cells. Importantly, the effect was not due to changing HSD17B4 expression directly, but by inhibiting its activity instead.
Overall, our results suggest that γ-T3 could be a promising treatment option for liver cancer, especially in targeting cancer growth pathways.
Read More
8
Vitamin E may reduce liver fibrosis
Negative association of composite dietary antioxidant index with risk of hepatic fibrosis in individuals underwent cholecystectomy: a cross-sectional study.
Strong association with liver health
We investigated the link between dietary antioxidants, including vitamin E, and the risk of liver fibrosis in people who had gallbladder surgery. Analyzing data from 773 participants, we calculated the composite dietary antioxidant index, which showed a negative association with hepatic fibrosis risk.
The results revealed that higher antioxidant intake, particularly vitamin E, was related to a reduced risk of liver fibrosis. However, there wasn’t a significant impact observed on metabolic dysfunction-associated fatty liver disease. Overall, our findings suggest that boosting antioxidant intake could help protect the liver.
The results revealed that higher antioxidant intake, particularly vitamin E, was related to a reduced risk of liver fibrosis. However, there wasn’t a significant impact observed on metabolic dysfunction-associated fatty liver disease. Overall, our findings suggest that boosting antioxidant intake could help protect the liver.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
8.8
Liver protection benefits
I acquired this for pre-alcohol consumption. I've trusted Thorne for years, knowing they have in-house labs for testing. I recently heard a Huberman Lab podcast explaining how taking vitamin E before or shortly after alcohol can mitigate the negative impacts on our liver, so I'm giving it a try!
Read More
Frequently Asked Questions
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