Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 2 Reviews
8.4

Top Medical Research Studies

8
Zinc's complex role in prostate cancer
We explored the relationship between zinc levels and prostate cancer treatments, particularly focusing on a novel compound known as 3D. This compound showed a strong potential to target prostate cancer cells, contributing to a decrease in their proliferation rates.

Our analysis revealed that compound 3D selectively impacted key metabolic processes in prostate cancer cells by suppressing factors related to energy production, such as lactate levels. Interestingly, it also reduced the activity of transporters involved in zinc absorption while leaving those responsible for zinc export untouched.

We also found that the effectiveness of 3D could be reversed with zinc treatment, highlighting a complicated interaction between zinc and this therapeutic approach. While the compound successfully lowered zinc levels in cells and inhibited cancer growth, it is essential to note that we did not find significant benefits from zinc treatment by itself in the context of this study.

Overall, our findings suggest that targeting zinc metabolism and enhancing heme oxygenase-1 expression could be a promising strategy in prostate cancer therapy, more so than the direct application of zinc itself. The results illustrate the potential for combining innovative small molecules with an understanding of cancer metabolism in the development of treatment strategies.
Read More

Most Useful Reviews

9
Risk reduction
3 people found this helpful
Prostate Plus caught my attention as I was on Testosterone Replacement Therapy, which poses risks to prostate health. This product has been formulated to reduce those risks while promoting prostate health, and I have seen positive results over 20 years of use.
Read More
7.5
Gradual improvement
66 people found this helpful
My prostate issues were severe, but after starting this product, I noticed improvements after a week. By the 15th day, my waiting time to urinate had decreased, and nighttime visits are now fewer.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
  • All Researches
8
Zinc's complex role in prostate cancer
We explored the relationship between zinc levels and prostate cancer treatments, particularly focusing on a novel compound known as 3D. This compound showed a strong potential to target prostate cancer cells, contributing to a decrease in their proliferation rates.

Our analysis revealed that compound 3D selectively impacted key metabolic processes in prostate cancer cells by suppressing factors related to energy production, such as lactate levels. Interestingly, it also reduced the activity of transporters involved in zinc absorption while leaving those responsible for zinc export untouched.

We also found that the effectiveness of 3D could be reversed with zinc treatment, highlighting a complicated interaction between zinc and this therapeutic approach. While the compound successfully lowered zinc levels in cells and inhibited cancer growth, it is essential to note that we did not find significant benefits from zinc treatment by itself in the context of this study.

Overall, our findings suggest that targeting zinc metabolism and enhancing heme oxygenase-1 expression could be a promising strategy in prostate cancer therapy, more so than the direct application of zinc itself. The results illustrate the potential for combining innovative small molecules with an understanding of cancer metabolism in the development of treatment strategies.
Read More

User Reviews

USERS' SCORE
Good
Based on 2 Reviews
8.4
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Risk reduction
3 people found this helpful
Prostate Plus caught my attention as I was on Testosterone Replacement Therapy, which poses risks to prostate health. This product has been formulated to reduce those risks while promoting prostate health, and I have seen positive results over 20 years of use.
Read More
7.5
Gradual improvement
66 people found this helpful
My prostate issues were severe, but after starting this product, I noticed improvements after a week. By the 15th day, my waiting time to urinate had decreased, and nighttime visits are now fewer.
Read More

Frequently Asked Questions

No FAQs are available for this product and symptom.

References

  1. Ghimire K, Awasthi BP, Yadav K, Lee J, Kim H, et al. Prostate cancer-selective anticancer action of an oxindole derivative via HO-1-mediated disruption of metabolic reprogramming. Chem Biol Interact. 2025;408:111393. doi:10.1016/j.cbi.2025.111393
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