Qunol Ubiquinol CoQ10 200mg

We aimed to understand how ubiquinol, also known as coenzyme Q10 (CoQ-10), can impact those suffering from heart failure (HF). To do this, we conducted a thorough review of existing studies, searching databases like MEDLINE and the Cochrane Library for relevant literature.

Throughout our evaluation, we focused on key outcomes: whether CoQ-10 could reduce HF-related mortality, improve patients' exercise capacity, and affect the left ventricular ejection fraction (LVEF). Our analysis included findings from 16 different studies that provided intriguing insights.

Notably, we observed that CoQ-10 was effective in reducing HF-related mortality by an impressive 40%. Additionally, patients taking CoQ-10 reported enhanced exercise capacity, which is crucial for improving their quality of life. However, when it came to the left ventricular ejection fraction, the results were less clear; we found no significant difference, though we acknowledge that further research is needed to fully explore its potential effects in this area.

In summary, CoQ-10 shows promise in supporting heart failure patients by reducing mortality and boosting exercise capacity, but its role related to LVEF still warrants additional exploration.

8.8

Reduced heart disease

Most Useful Review

When applied, the main benefits are reduced risk of cardiovascular disease, suppression of free radicals, enhanced mental and physical performance, and improved immunity. Coenzyme can mitigate ultraviolet damage, slowing skin ageing. It is recommended for those over 35 to take ubihonol consistently at 100 mg daily, ideally during or after a meal for best absorption.

Melatonin/nicotinamide mononucleotide/ubiquinol: a cocktail providing superior cardioprotection against ischemia/reperfusion injury in a common co-morbidities modelled rat.

Most Relevant Research

We designed a study with male Wistar rats, aged 22-24 months and induced with type-2 diabetes, to investigate how a combination of three mitochondrial agents—melatonin, nicotinamide mononucleotide (NMN), and ubiquinol—could provide protection against myocardial ischemia/reperfusion (I/R) injury, especially in the context of aging and diabetes.

The rats were split into groups receiving different treatments, including some that received the cocktail of supplements just during the reperfusion phase after inducing I/R injury. Over 28 days leading up to the tests, rats received NMN, while melatonin and ubiquinol were administered as the heart was being revived after ischemia.

The results indicated that the combination therapy notably enhanced heart protection and improved mitochondrial function and biogenesis in these aged diabetic rats. While ubiquinol was an important part of this cocktail, it is essential to view its role as one among several synergistic agents. This points to exciting possibilities for improved heart health strategies, particularly for older individuals with diabetes.

9.5

Heart rhythm improvement

Most Useful Review

I highly recommend this coenzyme Q10, especially after experiencing heart rhythm issues, including tachycardia. After a month of taking it, my symptoms improved significantly, and I feel much better overall. It's easy to use, just one daily capsule after meals. I plan to keep using it since it's suggested for those over 40.