Melatonin benefits in autism modelsMelatonin improves synapse development by PI3K/Akt signaling in a mouse model of autism spectrum disorder.
We investigated the role of melatonin in enhancing synaptic development in mouse models of autism. Through long-term oral administration over 28 days, melatonin improved social interactions and dendritic spine density in genetically modified mice.
Importantly, we found that melatonin's benefits are linked to the activation of a specific signaling pathway in the brain. However, when this pathway was blocked, the positive effects of melatonin on synaptic function were diminished. Overall, our findings highlight melatonin's promise for addressing certain autism-related challenges.
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These help my son fall asleep like clockwork and achieve a great night's rest. He has autism and ADHD, and after starting stimulant medications, he struggled to sleep. He hadn’t had issues with sleep previously. He prefers these gummy melatonins over pills. They assist him in falling asleep effectively without any adverse reactions with his medications. I enjoy the flavour as well, which helped me after a recent long flight.