Supplement Facts
Serving Size: 2 Gummies
Amount Per Serving
%DV
Calories
15
Total Carbohydrate
4 g
1%†
Sugar Alcohol
4 g
**
Melatonin
3 mg
**
Passion Flower (Passiflora incarnata) 4:1 extract
4.25 mg
**
Chamomile Flower (Chamomilla recutita) 4:1 extract
4.25 mg
**
Lemon Balm Leaf (Melissa officinalis) 4:1 extract
4 mg
**
The product is found useful for the following medical conditions
Insomnia details
SCIENTIFIC SCORE
Possibly Effective
Based on 23 Researches
7.8
USERS' SCORE
Good
Based on 23 Reviews
8.6
9
We developed a new way to deliver melatonin for those struggling with insomnia by creating microneedles made from silk fibroin. These tiny needles are designed to improve how the body absorbs melatonin, making it easier for people to get to sleep and stay asleep.
Our research shows that these microneedles can release melatonin steadily over a period of 11 hours. When we tested it on animals, we found that the microneedles maintained stable levels of drug in the bloodstream for up to 8 hours. This is promising news for individuals who may need help with their sleep cycles.
Additionally, the microneedles not only helped regulate sleep but also made a noticeable difference in anxiety levels in insomnia model rats. By improving the disrupted circadian rhythms, melatonin loaded into these microneedles could lead to significant therapeutic benefits.
We believe this innovative approach could enhance patient compliance and provide effective sleep aid for many in need. It’s an exciting development in the field of transdermal drug delivery for improving sleep quality and overcoming insomnia.
Our research shows that these microneedles can release melatonin steadily over a period of 11 hours. When we tested it on animals, we found that the microneedles maintained stable levels of drug in the bloodstream for up to 8 hours. This is promising news for individuals who may need help with their sleep cycles.
Additionally, the microneedles not only helped regulate sleep but also made a noticeable difference in anxiety levels in insomnia model rats. By improving the disrupted circadian rhythms, melatonin loaded into these microneedles could lead to significant therapeutic benefits.
We believe this innovative approach could enhance patient compliance and provide effective sleep aid for many in need. It’s an exciting development in the field of transdermal drug delivery for improving sleep quality and overcoming insomnia.
10
Better than prescriptions
Most Useful Review
14 people found this helpful
I absolutely love it! I’m a terribly restless sleeper prone to insomnia, worsened by hyperthyroidism. Two or three of these gummies, and 20-30 minutes later, I'm OUT. If I wake up during the night, I may need another, but they always work better than prescription medications, which astonishes me. They taste great, too! I will definitely keep these on hand.
Anxiety details
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7
USERS' SCORE
Good
Based on 2 Reviews
8.4
9
Melatonin reduces pediatric anxiety, pain
We focused on the effects of oral melatonin on anxiety and pain in children during the stressful process of venipuncture. In a double-blind, randomized controlled trial, we found that administering 0.5 mg/kg of melatonin 30 minutes before the procedure significantly reduced both pain and anxiety levels compared to a placebo.
The results showed that only 18.8% of the kids receiving melatonin reported pain, while 78.2% in the placebo group did. Furthermore, anxiety affected 44.6% of the melatonin group compared to 94.1% of those in the control group.
While melatonin appeared to improve experiences during venipuncture, its impact on the success rate was not statistically significant.
The results showed that only 18.8% of the kids receiving melatonin reported pain, while 78.2% in the placebo group did. Furthermore, anxiety affected 44.6% of the melatonin group compared to 94.1% of those in the control group.
While melatonin appeared to improve experiences during venipuncture, its impact on the success rate was not statistically significant.
9
Reliable for anxiety
Most Useful Review
1 people found this helpful
"Mama said knock you out!" (Seriously, they're effective.) I keep these on hand for my little one, who suffers from severe anxiety, and they work wonderfully! I appreciate the small dosage, and they prove to be a trustworthy product, unlike other melatonin gummies we've tried, which lacked consistency.
Sleep Apnea details
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.6
USERS' SCORE
Good
Based on 33 Reviews
8.3
9.5
Melatonin improves sleep apnea outcomes
We investigated how melatonin affects patients with obstructive sleep apnea and insomnia. In a double-blind trial, thirty patients received either 10 mg of melatonin or a placebo for a month.
The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.
Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.
Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
9
Improved sleep quality
Most Useful Review
10 people found this helpful
The Marmalade Miracle has worked wonders for my husband, who suffers from insomnia. He often tumbles around the flat, but these chewable vitamins help him sleep soundly. Just half an hour after taking them, he enters a peaceful slumber.
