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SCIENTIFIC SCORE
Moderately Effective
Based on 11 Researches
8.4
USERS' SCORE
Good
Based on 1 Review
8.5
Supplement Facts
Serving Size: 1 Packet (10 g)
Amount Per Serving
%DV
Calories
35
Protein
9 g
0%*
Sodium
55 mg
2%
Collagen peptides (from bovine)
10 g
**
Top Medical Research Studies
9
Microneedling depth impacts scars
Evaluation of microneedling depth of penetration in management of atrophic acne scars: a split-face comparative study.
Moderate relevance to collagen treatment
In our exploration of treating atrophic acne scars, we focused on the effects of different microneedling depths using Dermapen. We designed a split-face study involving 14 individuals, where each side of their face received a different treatment depth over six sessions, spaced two weeks apart.
On one side, the needles penetrated 2.5 mm into the skin, while the other side used 1.5 mm. We observed a noticeable difference in the improvement of scars, with the deeper 2.5 mm treatment showing significantly better results both clinically and at a cellular level.
The findings suggest that deeper microneedling might foster better collagen induction, which is crucial for skin repair. Both treatments improved collagen and elastin fibers, but the more profound impact from the deeper needles highlights how penetration depth might be a key factor in achieving effective results in scar management.
On one side, the needles penetrated 2.5 mm into the skin, while the other side used 1.5 mm. We observed a noticeable difference in the improvement of scars, with the deeper 2.5 mm treatment showing significantly better results both clinically and at a cellular level.
The findings suggest that deeper microneedling might foster better collagen induction, which is crucial for skin repair. Both treatments improved collagen and elastin fibers, but the more profound impact from the deeper needles highlights how penetration depth might be a key factor in achieving effective results in scar management.
Read More
9
Promising peptides for acne treatment
Novel-designed antimicrobial peptides with dual antimicrobial and anti-inflammatory actions against Cutibacterium acnes for acne vulgaris therapy.
High relevance to acne treatment
We explored the potential of novel antimicrobial peptides (AMPs) designed to combat acne vulgaris, a common skin issue caused by the bacteria Cutibacterium acnes. Traditional treatments often lead to antibiotic resistance and unwanted side effects, prompting the need for alternative solutions.
Our approach involved creating short peptides made up of 13 amino acids. We specifically tweaked these peptides by adjusting the number and position of tryptophan residues to enhance their effectiveness. Among the various peptides synthesized, we found that DAP-7 and DAP-10 stood out for their strong antimicrobial properties against both antibiotic-sensitive and -resistant strains of C. acnes, while causing minimal damage to human cells.
By targeting the bacterial membrane, these peptides can disrupt the bacteria, leading to their breakdown. Additionally, DAP-7 and DAP-10 were effective in reducing the levels of inflammation linked to acne. Remarkably, DAP-7 resulted not only in fewer C. acnes colonies but also significantly decreased swelling in a mouse model of acne.
Our findings indicate that DAP-7 and DAP-10 are promising options for developing new acne treatments, offering a dual action that tackles both the bacteria and the associated inflammation.
Our approach involved creating short peptides made up of 13 amino acids. We specifically tweaked these peptides by adjusting the number and position of tryptophan residues to enhance their effectiveness. Among the various peptides synthesized, we found that DAP-7 and DAP-10 stood out for their strong antimicrobial properties against both antibiotic-sensitive and -resistant strains of C. acnes, while causing minimal damage to human cells.
By targeting the bacterial membrane, these peptides can disrupt the bacteria, leading to their breakdown. Additionally, DAP-7 and DAP-10 were effective in reducing the levels of inflammation linked to acne. Remarkably, DAP-7 resulted not only in fewer C. acnes colonies but also significantly decreased swelling in a mouse model of acne.
Our findings indicate that DAP-7 and DAP-10 are promising options for developing new acne treatments, offering a dual action that tackles both the bacteria and the associated inflammation.
Read More
8
Identifying proteins linked to acne
Unveiling new protein biomarkers and therapeutic targets for acne through integrated analysis of human plasma proteomics and genomics.
Significant findings on acne treatment
We investigated how specific proteins influence the development of acne by analyzing extensive data from a large cohort. In a study involving over 54,000 participants, we examined the relationship between nearly 3,000 serum proteins and the onset of acne.
Our analysis revealed 19 proteins significantly linked to acne risk. Among these, two proteins stood out—FSTL1 and ANXA5. We found that higher levels of these proteins were associated with an increased likelihood of developing acne, with each one-standard deviation rise corresponding to a 24% and 32% increase in acne incidence, respectively.
Using advanced genetic analysis methods, we confirmed these findings and suggested that these proteins could be valuable targets for new acne treatments. This work highlights the potential for protein-based approaches in tackling acne effectively.
Our analysis revealed 19 proteins significantly linked to acne risk. Among these, two proteins stood out—FSTL1 and ANXA5. We found that higher levels of these proteins were associated with an increased likelihood of developing acne, with each one-standard deviation rise corresponding to a 24% and 32% increase in acne incidence, respectively.
Using advanced genetic analysis methods, we confirmed these findings and suggested that these proteins could be valuable targets for new acne treatments. This work highlights the potential for protein-based approaches in tackling acne effectively.
Read More
Most Useful Reviews
8
Reduced acne significantly
Great protein powder with a neutral taste. I started using this about 4 months ago. It mixes easily into a hot drink (less so into a cold drink) and has a neutral flavour. I add it to my coffee each morning, and I can't tell there's anything extra added. During workouts, it provides a calorie boost. My skin has greatly improved, and I experience less acne than before. I've also adapted my diet and increased my water intake, so the enhancement likely stems from various changes.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 11 Researches
8.4
9
Afzelin reduces acne inflammation
Effect of afzelin on inflammation and lipogenesis in particulate matter-stimulated treated SZ95 sebocytes.
Study highlights protein's limited impact
We focused on exploring how afzelin, a natural flavonoid known for its anti-inflammatory effects, influences acne-related inflammation and sebum production in a specific type of skin cell called SZ95 sebocytes. To set the stage for our investigation, we simulated an acne-like condition by introducing heat-killed bacteria into the cells, along with exposure to particulate matter (PM).
We observed that PM may worsen acne by increasing inflammatory responses and promoting sebum secretion. Excitingly, when we treated these cells with afzelin, we found that it significantly reduced the inflammatory cytokine levels and inhibited the processes that lead to excess oil production. This suggests that afzelin could serve as a beneficial treatment option for alleviating PM-related acne.
Overall, our findings highlight the dual role of afzelin in combating acne by addressing both inflammation and sebum overproduction, positioning it as a potential therapeutic agent in skincare treatments.
We observed that PM may worsen acne by increasing inflammatory responses and promoting sebum secretion. Excitingly, when we treated these cells with afzelin, we found that it significantly reduced the inflammatory cytokine levels and inhibited the processes that lead to excess oil production. This suggests that afzelin could serve as a beneficial treatment option for alleviating PM-related acne.
Overall, our findings highlight the dual role of afzelin in combating acne by addressing both inflammation and sebum overproduction, positioning it as a potential therapeutic agent in skincare treatments.
Read More
9
Peptide combination enhances acne treatment
The combination of RL-QN15 and OH-CATH30 promotes the repair of acne via the TLR2/NF-κB pathway.
Combination treatment shows promise
We investigated the impact of two peptides, RL-QN15 and OH-CATH30, on treating acne in mice. Our findings revealed that when applied together, these peptides significantly reduced the growth of Propionibacterium acnes, the bacteria responsible for acne, and decreased the associated swelling.
Alongside tackling the bacteria, this combination also helped lower the production of inflammatory molecules, such as IL-1β and TNF-α, which are known to worsen acne condition. Notably, the treatment encouraged collagen production, promoting better skin repair and healing.
From a biological standpoint, we learned that RL-QN15 and OH-CATH30 work by suppressing the toll-like receptor 2 (TLR2) and the NF-κB signaling pathway, which ultimately reduces inflammation and aids in skin recovery. This points to their potential as a promising strategy for acne therapy, emphasizing the importance of looking at innovative protein combinations.
Overall, our study highlights a new, effective approach in tackling the persistent issue of acne. By focusing on these combined proteins, we are paving the way for advanced treatment options that could significantly improve the quality of life for those suffering from this common skin condition.
Alongside tackling the bacteria, this combination also helped lower the production of inflammatory molecules, such as IL-1β and TNF-α, which are known to worsen acne condition. Notably, the treatment encouraged collagen production, promoting better skin repair and healing.
From a biological standpoint, we learned that RL-QN15 and OH-CATH30 work by suppressing the toll-like receptor 2 (TLR2) and the NF-κB signaling pathway, which ultimately reduces inflammation and aids in skin recovery. This points to their potential as a promising strategy for acne therapy, emphasizing the importance of looking at innovative protein combinations.
Overall, our study highlights a new, effective approach in tackling the persistent issue of acne. By focusing on these combined proteins, we are paving the way for advanced treatment options that could significantly improve the quality of life for those suffering from this common skin condition.
Read More
9
Promising peptides for acne treatment
Novel-designed antimicrobial peptides with dual antimicrobial and anti-inflammatory actions against Cutibacterium acnes for acne vulgaris therapy.
High relevance to acne treatment
We explored the potential of novel antimicrobial peptides (AMPs) designed to combat acne vulgaris, a common skin issue caused by the bacteria Cutibacterium acnes. Traditional treatments often lead to antibiotic resistance and unwanted side effects, prompting the need for alternative solutions.
Our approach involved creating short peptides made up of 13 amino acids. We specifically tweaked these peptides by adjusting the number and position of tryptophan residues to enhance their effectiveness. Among the various peptides synthesized, we found that DAP-7 and DAP-10 stood out for their strong antimicrobial properties against both antibiotic-sensitive and -resistant strains of C. acnes, while causing minimal damage to human cells.
By targeting the bacterial membrane, these peptides can disrupt the bacteria, leading to their breakdown. Additionally, DAP-7 and DAP-10 were effective in reducing the levels of inflammation linked to acne. Remarkably, DAP-7 resulted not only in fewer C. acnes colonies but also significantly decreased swelling in a mouse model of acne.
Our findings indicate that DAP-7 and DAP-10 are promising options for developing new acne treatments, offering a dual action that tackles both the bacteria and the associated inflammation.
Our approach involved creating short peptides made up of 13 amino acids. We specifically tweaked these peptides by adjusting the number and position of tryptophan residues to enhance their effectiveness. Among the various peptides synthesized, we found that DAP-7 and DAP-10 stood out for their strong antimicrobial properties against both antibiotic-sensitive and -resistant strains of C. acnes, while causing minimal damage to human cells.
By targeting the bacterial membrane, these peptides can disrupt the bacteria, leading to their breakdown. Additionally, DAP-7 and DAP-10 were effective in reducing the levels of inflammation linked to acne. Remarkably, DAP-7 resulted not only in fewer C. acnes colonies but also significantly decreased swelling in a mouse model of acne.
Our findings indicate that DAP-7 and DAP-10 are promising options for developing new acne treatments, offering a dual action that tackles both the bacteria and the associated inflammation.
Read More
9
Microneedling depth impacts scars
Evaluation of microneedling depth of penetration in management of atrophic acne scars: a split-face comparative study.
Moderate relevance to collagen treatment
In our exploration of treating atrophic acne scars, we focused on the effects of different microneedling depths using Dermapen. We designed a split-face study involving 14 individuals, where each side of their face received a different treatment depth over six sessions, spaced two weeks apart.
On one side, the needles penetrated 2.5 mm into the skin, while the other side used 1.5 mm. We observed a noticeable difference in the improvement of scars, with the deeper 2.5 mm treatment showing significantly better results both clinically and at a cellular level.
The findings suggest that deeper microneedling might foster better collagen induction, which is crucial for skin repair. Both treatments improved collagen and elastin fibers, but the more profound impact from the deeper needles highlights how penetration depth might be a key factor in achieving effective results in scar management.
On one side, the needles penetrated 2.5 mm into the skin, while the other side used 1.5 mm. We observed a noticeable difference in the improvement of scars, with the deeper 2.5 mm treatment showing significantly better results both clinically and at a cellular level.
The findings suggest that deeper microneedling might foster better collagen induction, which is crucial for skin repair. Both treatments improved collagen and elastin fibers, but the more profound impact from the deeper needles highlights how penetration depth might be a key factor in achieving effective results in scar management.
Read More
9
Effective collagen treatments for scars
Efficacy of Polycaprolactone Threads in Treating Atrophic Acne Scars: A Split-face Comparative Study.
Moderate connection to collagen impact
We set out to explore the effectiveness of collagen treatment for atrophic acne scars using two different approaches: polycaprolactone (PCL) threads and microneedling combined with platelet-rich plasma (PRP). In our research, 24 patients participated in a split-face study where one side of the face was treated with PCL threads, and the other side underwent microneedling with PRP. Each participant received four sessions of microneedling on one side, while the other side was treated with just one session of threads.
After monitoring the patients for six months, we observed a significant improvement in skin texture and scar appearance. Specifically, 95.8% of patients noted progress on the side treated with threads compared to 83.3% on the microneedling side. Additionally, satisfaction ratings were notably higher among those who received the thread treatment.
Both procedures were associated with mild side effects, like transient swelling and redness, which cleared up quickly. Our findings suggest that PCL threads could be a promising collagen-boosting alternative for treating acne scars, providing effective results with minimal discomfort.
After monitoring the patients for six months, we observed a significant improvement in skin texture and scar appearance. Specifically, 95.8% of patients noted progress on the side treated with threads compared to 83.3% on the microneedling side. Additionally, satisfaction ratings were notably higher among those who received the thread treatment.
Both procedures were associated with mild side effects, like transient swelling and redness, which cleared up quickly. Our findings suggest that PCL threads could be a promising collagen-boosting alternative for treating acne scars, providing effective results with minimal discomfort.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.5
8
Reduced acne significantly
Great protein powder with a neutral taste. I started using this about 4 months ago. It mixes easily into a hot drink (less so into a cold drink) and has a neutral flavour. I add it to my coffee each morning, and I can't tell there's anything extra added. During workouts, it provides a calorie boost. My skin has greatly improved, and I experience less acne than before. I've also adapted my diet and increased my water intake, so the enhancement likely stems from various changes.
Read More
