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SCIENTIFIC SCORE
Possibly Effective
Based on 23 Researches
7.5
USERS' SCORE
Good
Based on 3 Reviews
8.7
Top Medical Research Studies
9.5
Iron treatment reduces anemia
Iron deficiency and anemia in pregnancy: a call to action!: -"If you don't take a temperature, you can't find a fever".
Focused study on anemia treatment
We examined how iron treatment specifically impacts anemia, particularly during pregnancy. Iron deficiency is a leading cause of anemia, and finding the right treatment is crucial for both mothers and their developing babies.
Our study focused on just the effects of iron without looking at other treatments. This clear approach allowed us to isolate the benefits of iron supplementation. The results were insightful, showing that iron treatment had measurable effects on reducing anemia.
However, we must be careful about overgeneralizing these findings. While our results indicate improvements, it's important to recognize that individual responses to iron may vary. Our findings highlight the importance of monitoring iron levels in pregnant women to effectively address anemia.
Our study focused on just the effects of iron without looking at other treatments. This clear approach allowed us to isolate the benefits of iron supplementation. The results were insightful, showing that iron treatment had measurable effects on reducing anemia.
However, we must be careful about overgeneralizing these findings. While our results indicate improvements, it's important to recognize that individual responses to iron may vary. Our findings highlight the importance of monitoring iron levels in pregnant women to effectively address anemia.
Read More
8
Iron treatment and CKD anemia
Iron in Chronic Kidney Disease and End-Stage Kidney Disease-Current Trends and Future Direction.
Strong relevance to kidney disease
We explored the critical relationship between iron treatment and anemia in chronic kidney disease (CKD). Anemia often arises in CKD patients, whether they are on dialysis or not, primarily due to erythropoietin deficiency. However, iron deficiency plays a significant role and can be categorized into absolute, caused by blood loss, or functional, which is affected by inflammation and high levels of hepcidin.
Hepcidin impedes the body’s ability to use iron effectively, trapping it where it's not accessible for red blood cell production. This disruption in iron metabolism also means that oral iron supplements may not work well, especially in advanced CKD. Therefore, we reviewed various intravenous (IV) iron formulations available for treatment and outlined the diagnostic criteria and treatment benchmarks for iron deficiency in CKD patients.
Our findings led us to consider future therapeutic directions to improve patient outcomes. With advancements in the understanding of iron’s role in this context, the hope is to enhance treatment strategies for managing anemia in CKD effectively.
Hepcidin impedes the body’s ability to use iron effectively, trapping it where it's not accessible for red blood cell production. This disruption in iron metabolism also means that oral iron supplements may not work well, especially in advanced CKD. Therefore, we reviewed various intravenous (IV) iron formulations available for treatment and outlined the diagnostic criteria and treatment benchmarks for iron deficiency in CKD patients.
Our findings led us to consider future therapeutic directions to improve patient outcomes. With advancements in the understanding of iron’s role in this context, the hope is to enhance treatment strategies for managing anemia in CKD effectively.
Read More
8
Ferric Carboxymaltose Replaces Iron Sucrose
A cost-effective innovation in anaemia management for paediatric patients with haemodialysis-dependent chronic kidney disease.
High relevance to pediatric anemia
We aimed to find a better way to manage anemia in pediatric patients undergoing hemodialysis. Traditionally, these patients receive intravenous (IV) iron therapy using iron sucrose, which requires frequent treatments and carries a risk of allergic reactions. Moving forward with a home hemodialysis program, we investigated ferric carboxymaltose as a safer and more effective alternative.
In our study, we looked closely at how ferric carboxymaltose performed in maintaining healthy levels of hemoglobin, transferrin saturation, and reticulocyte hemoglobin content over a 12-month period. We also compared its efficacy against traditional iron sucrose treatments. The results were encouraging, showing that ferric carboxymaltose not only matched the effectiveness of iron sucrose but also required fewer hospital visits, significantly easing the treatment burden on families.
Overall, our findings suggest that ferric carboxymaltose is both clinically effective and cost-efficient. By reducing the frequency of administration, this approach can enhance the quality of life for pediatric patients with anemia due to chronic kidney disease who depend on hemodialysis. We believe this innovation presents a promising shift in anemia management for this vulnerable population.
In our study, we looked closely at how ferric carboxymaltose performed in maintaining healthy levels of hemoglobin, transferrin saturation, and reticulocyte hemoglobin content over a 12-month period. We also compared its efficacy against traditional iron sucrose treatments. The results were encouraging, showing that ferric carboxymaltose not only matched the effectiveness of iron sucrose but also required fewer hospital visits, significantly easing the treatment burden on families.
Overall, our findings suggest that ferric carboxymaltose is both clinically effective and cost-efficient. By reducing the frequency of administration, this approach can enhance the quality of life for pediatric patients with anemia due to chronic kidney disease who depend on hemodialysis. We believe this innovation presents a promising shift in anemia management for this vulnerable population.
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Most Useful Reviews
9.5
Improving iron levels
Registered Dietitian Approved. As is common, I developed iron deficiency/anaemia after pregnancy. On my OBGYN's recommendation, I began additional supplementation beyond my prenatal vitamins with Vitron-C three weeks ago. Blood work today shows my anaemia has begun to improve. I chose Vitron-C for its carbonyl iron, which is easily absorbed, and I appreciate that they've added vitamin C to aid with absorption. I'm happy this supplement is working; it doesn't taste bad before swallowing and hasn't caused gastrointestinal issues.
Read More
9.5
Convenient dosage
Happy with these. My second order finally brought my anaemia into an acceptable range! The doctor had me on OTC iron three times a day. With these, I only need to take them once a day. They lack the iron taste and didn’t cause constipation, so I’m pleased.
Read More
8.8
Stomach-friendly
Good iron. This is one of the few brands that doesn’t upset my stomach. I've been using it for chronic anaemia for a few years now and it's been effective so far.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 23 Researches
7.5
9.5
Iron treatment reduces anemia
Iron deficiency and anemia in pregnancy: a call to action!: -"If you don't take a temperature, you can't find a fever".
Focused study on anemia treatment
We examined how iron treatment specifically impacts anemia, particularly during pregnancy. Iron deficiency is a leading cause of anemia, and finding the right treatment is crucial for both mothers and their developing babies.
Our study focused on just the effects of iron without looking at other treatments. This clear approach allowed us to isolate the benefits of iron supplementation. The results were insightful, showing that iron treatment had measurable effects on reducing anemia.
However, we must be careful about overgeneralizing these findings. While our results indicate improvements, it's important to recognize that individual responses to iron may vary. Our findings highlight the importance of monitoring iron levels in pregnant women to effectively address anemia.
Our study focused on just the effects of iron without looking at other treatments. This clear approach allowed us to isolate the benefits of iron supplementation. The results were insightful, showing that iron treatment had measurable effects on reducing anemia.
However, we must be careful about overgeneralizing these findings. While our results indicate improvements, it's important to recognize that individual responses to iron may vary. Our findings highlight the importance of monitoring iron levels in pregnant women to effectively address anemia.
Read More
9
Nano-Bhasma enhances iron absorption
Advancements in Nano-Mandoor Bhasma: Unravelling the Particle Size-Ascorbic Acid Synergy for Enhanced Iron Bioavailability for Anemia Treatment.
Moderate relevance with vitamin C
We investigated how modifying Mandoor Bhasma, a traditional Ayurvedic medicine, could enhance its effectiveness in treating iron-deficiency anemia. By grinding this medicine into nanoparticles and coating them with ascorbic acid, we aimed to boost the iron bioavailability in our body.
In our study, we found that the surface-enhanced nano-Mandoor Bhasma exhibited better iron dissolution in conditions similar to those found in our intestines. This improvement was significant because it means that more iron becomes available for our bodies to absorb. Testing the effects on human colon cells revealed that cells treated with the modified version absorbed three times more iron compared to those treated with the standard version.
Furthermore, as the treated cells produced higher levels of a key protein related to iron storage, this signals an increase in the iron available for our body’s needs. Ultimately, this research suggests that using nanoscale formulations and vitamin C can significantly enhance the effectiveness of traditional iron treatments for anemia.
In our study, we found that the surface-enhanced nano-Mandoor Bhasma exhibited better iron dissolution in conditions similar to those found in our intestines. This improvement was significant because it means that more iron becomes available for our bodies to absorb. Testing the effects on human colon cells revealed that cells treated with the modified version absorbed three times more iron compared to those treated with the standard version.
Furthermore, as the treated cells produced higher levels of a key protein related to iron storage, this signals an increase in the iron available for our body’s needs. Ultimately, this research suggests that using nanoscale formulations and vitamin C can significantly enhance the effectiveness of traditional iron treatments for anemia.
Read More
9
Novel chelate complex boosts iron
Harnessing the Power of a Novel Triple Chelate Complex in Fermented Probiotic Dairy Products: A Promising Solution for Combating Iron Deficiency Anemia.
Relevant but not conclusive
We examined a novel approach to combat iron deficiency anemia by focusing on a unique triple chelate complex that combines iron, vitamin C (ascorbic acid), and essential amino acids. Our findings revealed that this complex can effectively increase iron levels in the body, particularly in fermented dairy products.
Importantly, we found that the fortification of milk with this complex doesn't require high concentrations—just a mere 0.005 mol/L is enough for effective results. Through our experiments with rat models, we observed a significant boost in serum iron levels after administering the complex, achieving a rise of 14.0 mmol/L within just 24 hours.
Furthermore, we studied how these complexes affected the taste and quality of dairy products, demonstrating that even at very low concentrations, they maintained desirable physicochemical properties. Among the various compounds we tested, iron ascorbate lysinate stood out as the most promising candidate for enhancing iron levels, making it a potential game-changer in diets for those suffering from iron deficiency anemia.
However, while we acknowledge the crucial role vitamin C plays in improving iron absorption, our focus on the triple chelate mechanism makes it challenging to isolate its individual effects solely on anemia.
Importantly, we found that the fortification of milk with this complex doesn't require high concentrations—just a mere 0.005 mol/L is enough for effective results. Through our experiments with rat models, we observed a significant boost in serum iron levels after administering the complex, achieving a rise of 14.0 mmol/L within just 24 hours.
Furthermore, we studied how these complexes affected the taste and quality of dairy products, demonstrating that even at very low concentrations, they maintained desirable physicochemical properties. Among the various compounds we tested, iron ascorbate lysinate stood out as the most promising candidate for enhancing iron levels, making it a potential game-changer in diets for those suffering from iron deficiency anemia.
However, while we acknowledge the crucial role vitamin C plays in improving iron absorption, our focus on the triple chelate mechanism makes it challenging to isolate its individual effects solely on anemia.
Read More
9
Vitamin C aids anemia treatment
The Forgotten Disease in the 21st Century: Scurvy Outbreak in Hawassa Central Prison, Hawassa, Sidama, Southern Ethiopia, 2023.
Significant findings in scurvy cases
We observed a fascinating phenomenon related to vitamin C and anemia during a series of cases in a prison setting in Ethiopia. Specifically, we examined how scurvy, a disease caused by a lack of vitamin C, contributed to anemia among prisoners.
Our study focused on ten patients who were admitted for treatment, all of whom presented with some form of leg swelling or pain. After administering vitamin C in the form of ascorbic acid, we noted a significant increase in hemoglobin levels, rising from an average of 4.6 to 7.1 g/dL. This improvement indicates that vitamin C may play a crucial role in alleviating some anemia symptoms when the underlying cause is related to dietary deficiencies.
Additionally, through an observational study involving 67 other patients in the same prison, we confirmed that leg swelling and pain were common symptoms among those affected. With consistent therapeutic doses of vitamin C, all patients showed considerable improvement in their conditions.
Thus, we can conclude that vitamin C does seem to have a valuable effect on anemia caused by dietary deficiencies, particularly in high-risk environments like prisons. This finding encourages healthcare providers to remain vigilant about such nutritional deficiencies and highlights the importance of vitamin C in treatment.
Our study focused on ten patients who were admitted for treatment, all of whom presented with some form of leg swelling or pain. After administering vitamin C in the form of ascorbic acid, we noted a significant increase in hemoglobin levels, rising from an average of 4.6 to 7.1 g/dL. This improvement indicates that vitamin C may play a crucial role in alleviating some anemia symptoms when the underlying cause is related to dietary deficiencies.
Additionally, through an observational study involving 67 other patients in the same prison, we confirmed that leg swelling and pain were common symptoms among those affected. With consistent therapeutic doses of vitamin C, all patients showed considerable improvement in their conditions.
Thus, we can conclude that vitamin C does seem to have a valuable effect on anemia caused by dietary deficiencies, particularly in high-risk environments like prisons. This finding encourages healthcare providers to remain vigilant about such nutritional deficiencies and highlights the importance of vitamin C in treatment.
Read More
9
Vitamin C boosts iron absorption
Preparation, characterization, and bioavailability evaluation of antioxidant phosvitin peptide-ferrous complex.
Synergistic effect on absorption
We investigated how vitamin C can affect anemia, particularly through its interaction with a specific iron supplement called phosvitin peptide-ferrous complex. This complex is designed to enhance iron bioavailability, which is crucial in addressing iron deficiency anemia (IDA). Our analysis showed that when vitamin C was added to this complex, there was a notable increase in iron absorption.
The results indicated that the iron content increased significantly with the presence of vitamin C, which interacted synergistically to boost bioavailability. In fact, when vitamin C was added, the iron dialysis percentage increased, highlighting its potential role in improving the efficiency of iron absorption in the gut.
While our findings suggested significant benefits in enhancing iron absorption when combined with vitamin C, it's essential to recognize that the isolated effects of vitamin C on anemia were not fully evaluated in this study. Therefore, while the combination exhibited promising results, we can't definitively say that vitamin C alone provides a solution for anemia.
The results indicated that the iron content increased significantly with the presence of vitamin C, which interacted synergistically to boost bioavailability. In fact, when vitamin C was added, the iron dialysis percentage increased, highlighting its potential role in improving the efficiency of iron absorption in the gut.
While our findings suggested significant benefits in enhancing iron absorption when combined with vitamin C, it's essential to recognize that the isolated effects of vitamin C on anemia were not fully evaluated in this study. Therefore, while the combination exhibited promising results, we can't definitively say that vitamin C alone provides a solution for anemia.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.7
9.5
Convenient dosage
Happy with these. My second order finally brought my anaemia into an acceptable range! The doctor had me on OTC iron three times a day. With these, I only need to take them once a day. They lack the iron taste and didn’t cause constipation, so I’m pleased.
9.5
Improving iron levels
Registered Dietitian Approved. As is common, I developed iron deficiency/anaemia after pregnancy. On my OBGYN's recommendation, I began additional supplementation beyond my prenatal vitamins with Vitron-C three weeks ago. Blood work today shows my anaemia has begun to improve. I chose Vitron-C for its carbonyl iron, which is easily absorbed, and I appreciate that they've added vitamin C to aid with absorption. I'm happy this supplement is working; it doesn't taste bad before swallowing and hasn't caused gastrointestinal issues.
Read More
8.8
Stomach-friendly
Good iron. This is one of the few brands that doesn’t upset my stomach. I've been using it for chronic anaemia for a few years now and it's been effective so far.
