Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 37 Researches
7.6
USERS' SCORE
Good
Based on 3 Reviews
8.5
Top Medical Research Studies
9.5
We examined how iron treatment specifically impacts anemia, particularly during pregnancy. Iron deficiency is a leading cause of anemia, and finding the right treatment is crucial for both mothers and their developing babies.
Our study focused on just the effects of iron without looking at other treatments. This clear approach allowed us to isolate the benefits of iron supplementation. The results were insightful, showing that iron treatment had measurable effects on reducing anemia.
However, we must be careful about overgeneralizing these findings. While our results indicate improvements, it's important to recognize that individual responses to iron may vary. Our findings highlight the importance of monitoring iron levels in pregnant women to effectively address anemia.
Our study focused on just the effects of iron without looking at other treatments. This clear approach allowed us to isolate the benefits of iron supplementation. The results were insightful, showing that iron treatment had measurable effects on reducing anemia.
However, we must be careful about overgeneralizing these findings. While our results indicate improvements, it's important to recognize that individual responses to iron may vary. Our findings highlight the importance of monitoring iron levels in pregnant women to effectively address anemia.
Read More
8
We explored the critical relationship between iron treatment and anemia in chronic kidney disease (CKD). Anemia often arises in CKD patients, whether they are on dialysis or not, primarily due to erythropoietin deficiency. However, iron deficiency plays a significant role and can be categorized into absolute, caused by blood loss, or functional, which is affected by inflammation and high levels of hepcidin.
Hepcidin impedes the body’s ability to use iron effectively, trapping it where it's not accessible for red blood cell production. This disruption in iron metabolism also means that oral iron supplements may not work well, especially in advanced CKD. Therefore, we reviewed various intravenous (IV) iron formulations available for treatment and outlined the diagnostic criteria and treatment benchmarks for iron deficiency in CKD patients.
Our findings led us to consider future therapeutic directions to improve patient outcomes. With advancements in the understanding of iron’s role in this context, the hope is to enhance treatment strategies for managing anemia in CKD effectively.
Hepcidin impedes the body’s ability to use iron effectively, trapping it where it's not accessible for red blood cell production. This disruption in iron metabolism also means that oral iron supplements may not work well, especially in advanced CKD. Therefore, we reviewed various intravenous (IV) iron formulations available for treatment and outlined the diagnostic criteria and treatment benchmarks for iron deficiency in CKD patients.
Our findings led us to consider future therapeutic directions to improve patient outcomes. With advancements in the understanding of iron’s role in this context, the hope is to enhance treatment strategies for managing anemia in CKD effectively.
Read More
8
We aimed to find a better way to manage anemia in pediatric patients undergoing hemodialysis. Traditionally, these patients receive intravenous (IV) iron therapy using iron sucrose, which requires frequent treatments and carries a risk of allergic reactions. Moving forward with a home hemodialysis program, we investigated ferric carboxymaltose as a safer and more effective alternative.
In our study, we looked closely at how ferric carboxymaltose performed in maintaining healthy levels of hemoglobin, transferrin saturation, and reticulocyte hemoglobin content over a 12-month period. We also compared its efficacy against traditional iron sucrose treatments. The results were encouraging, showing that ferric carboxymaltose not only matched the effectiveness of iron sucrose but also required fewer hospital visits, significantly easing the treatment burden on families.
Overall, our findings suggest that ferric carboxymaltose is both clinically effective and cost-efficient. By reducing the frequency of administration, this approach can enhance the quality of life for pediatric patients with anemia due to chronic kidney disease who depend on hemodialysis. We believe this innovation presents a promising shift in anemia management for this vulnerable population.
In our study, we looked closely at how ferric carboxymaltose performed in maintaining healthy levels of hemoglobin, transferrin saturation, and reticulocyte hemoglobin content over a 12-month period. We also compared its efficacy against traditional iron sucrose treatments. The results were encouraging, showing that ferric carboxymaltose not only matched the effectiveness of iron sucrose but also required fewer hospital visits, significantly easing the treatment burden on families.
Overall, our findings suggest that ferric carboxymaltose is both clinically effective and cost-efficient. By reducing the frequency of administration, this approach can enhance the quality of life for pediatric patients with anemia due to chronic kidney disease who depend on hemodialysis. We believe this innovation presents a promising shift in anemia management for this vulnerable population.
Read More
Most Useful Reviews
9
Improving iron levels
3 people found this helpful
Registered Dietitian Approved. As is common, I developed iron deficiency/anaemia after pregnancy. On my OBGYN's recommendation, I began additional supplementation beyond my prenatal vitamins with Vitron-C three weeks ago. Blood work today shows my anaemia has begun to improve. I chose Vitron-C for its carbonyl iron, which is easily absorbed, and I appreciate that they've added vitamin C to aid with absorption. I'm happy this supplement is working; it doesn't taste bad before swallowing and hasn't caused gastrointestinal issues.
Read More
9
Convenient dosage
1 people found this helpful
Happy with these. My second order finally brought my anaemia into an acceptable range! The doctor had me on OTC iron three times a day. With these, I only need to take them once a day. They lack the iron taste and didn’t cause constipation, so I’m pleased.
Read More
7.5
Stomach-friendly
3 people found this helpful
Good iron. This is one of the few brands that doesn’t upset my stomach. I've been using it for chronic anaemia for a few years now and it's been effective so far.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 37 Researches
7.6
- All Researches
9.5
We examined how iron treatment specifically impacts anemia, particularly during pregnancy. Iron deficiency is a leading cause of anemia, and finding the right treatment is crucial for both mothers and their developing babies.
Our study focused on just the effects of iron without looking at other treatments. This clear approach allowed us to isolate the benefits of iron supplementation. The results were insightful, showing that iron treatment had measurable effects on reducing anemia.
However, we must be careful about overgeneralizing these findings. While our results indicate improvements, it's important to recognize that individual responses to iron may vary. Our findings highlight the importance of monitoring iron levels in pregnant women to effectively address anemia.
Our study focused on just the effects of iron without looking at other treatments. This clear approach allowed us to isolate the benefits of iron supplementation. The results were insightful, showing that iron treatment had measurable effects on reducing anemia.
However, we must be careful about overgeneralizing these findings. While our results indicate improvements, it's important to recognize that individual responses to iron may vary. Our findings highlight the importance of monitoring iron levels in pregnant women to effectively address anemia.
Read More
9.5
We explored the challenges of diagnosing hookworm infections, particularly in severe cases. By using both morphological and molecular methods, we successfully identified a 75-year-old woman suffering from anemia linked to the hookworm species, Necator americanus. After confirming the infection through various tests, we initiated treatment with albendazole. Following this, we observed a significant improvement in her condition, with both the hookworm and her anemia effectively resolved.
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9
Nano-Bhasma enhances iron absorption
We investigated how modifying Mandoor Bhasma, a traditional Ayurvedic medicine, could enhance its effectiveness in treating iron-deficiency anemia. By grinding this medicine into nanoparticles and coating them with ascorbic acid, we aimed to boost the iron bioavailability in our body.
In our study, we found that the surface-enhanced nano-Mandoor Bhasma exhibited better iron dissolution in conditions similar to those found in our intestines. This improvement was significant because it means that more iron becomes available for our bodies to absorb. Testing the effects on human colon cells revealed that cells treated with the modified version absorbed three times more iron compared to those treated with the standard version.
Furthermore, as the treated cells produced higher levels of a key protein related to iron storage, this signals an increase in the iron available for our body’s needs. Ultimately, this research suggests that using nanoscale formulations and vitamin C can significantly enhance the effectiveness of traditional iron treatments for anemia.
In our study, we found that the surface-enhanced nano-Mandoor Bhasma exhibited better iron dissolution in conditions similar to those found in our intestines. This improvement was significant because it means that more iron becomes available for our bodies to absorb. Testing the effects on human colon cells revealed that cells treated with the modified version absorbed three times more iron compared to those treated with the standard version.
Furthermore, as the treated cells produced higher levels of a key protein related to iron storage, this signals an increase in the iron available for our body’s needs. Ultimately, this research suggests that using nanoscale formulations and vitamin C can significantly enhance the effectiveness of traditional iron treatments for anemia.
Read More
9
Novel chelate complex boosts iron
We examined a novel approach to combat iron deficiency anemia by focusing on a unique triple chelate complex that combines iron, vitamin C (ascorbic acid), and essential amino acids. Our findings revealed that this complex can effectively increase iron levels in the body, particularly in fermented dairy products.
Importantly, we found that the fortification of milk with this complex doesn't require high concentrations—just a mere 0.005 mol/L is enough for effective results. Through our experiments with rat models, we observed a significant boost in serum iron levels after administering the complex, achieving a rise of 14.0 mmol/L within just 24 hours.
Furthermore, we studied how these complexes affected the taste and quality of dairy products, demonstrating that even at very low concentrations, they maintained desirable physicochemical properties. Among the various compounds we tested, iron ascorbate lysinate stood out as the most promising candidate for enhancing iron levels, making it a potential game-changer in diets for those suffering from iron deficiency anemia.
However, while we acknowledge the crucial role vitamin C plays in improving iron absorption, our focus on the triple chelate mechanism makes it challenging to isolate its individual effects solely on anemia.
Importantly, we found that the fortification of milk with this complex doesn't require high concentrations—just a mere 0.005 mol/L is enough for effective results. Through our experiments with rat models, we observed a significant boost in serum iron levels after administering the complex, achieving a rise of 14.0 mmol/L within just 24 hours.
Furthermore, we studied how these complexes affected the taste and quality of dairy products, demonstrating that even at very low concentrations, they maintained desirable physicochemical properties. Among the various compounds we tested, iron ascorbate lysinate stood out as the most promising candidate for enhancing iron levels, making it a potential game-changer in diets for those suffering from iron deficiency anemia.
However, while we acknowledge the crucial role vitamin C plays in improving iron absorption, our focus on the triple chelate mechanism makes it challenging to isolate its individual effects solely on anemia.
Read More
9
We observed a fascinating phenomenon related to vitamin C and anemia during a series of cases in a prison setting in Ethiopia. Specifically, we examined how scurvy, a disease caused by a lack of vitamin C, contributed to anemia among prisoners.
Our study focused on ten patients who were admitted for treatment, all of whom presented with some form of leg swelling or pain. After administering vitamin C in the form of ascorbic acid, we noted a significant increase in hemoglobin levels, rising from an average of 4.6 to 7.1 g/dL. This improvement indicates that vitamin C may play a crucial role in alleviating some anemia symptoms when the underlying cause is related to dietary deficiencies.
Additionally, through an observational study involving 67 other patients in the same prison, we confirmed that leg swelling and pain were common symptoms among those affected. With consistent therapeutic doses of vitamin C, all patients showed considerable improvement in their conditions.
Thus, we can conclude that vitamin C does seem to have a valuable effect on anemia caused by dietary deficiencies, particularly in high-risk environments like prisons. This finding encourages healthcare providers to remain vigilant about such nutritional deficiencies and highlights the importance of vitamin C in treatment.
Our study focused on ten patients who were admitted for treatment, all of whom presented with some form of leg swelling or pain. After administering vitamin C in the form of ascorbic acid, we noted a significant increase in hemoglobin levels, rising from an average of 4.6 to 7.1 g/dL. This improvement indicates that vitamin C may play a crucial role in alleviating some anemia symptoms when the underlying cause is related to dietary deficiencies.
Additionally, through an observational study involving 67 other patients in the same prison, we confirmed that leg swelling and pain were common symptoms among those affected. With consistent therapeutic doses of vitamin C, all patients showed considerable improvement in their conditions.
Thus, we can conclude that vitamin C does seem to have a valuable effect on anemia caused by dietary deficiencies, particularly in high-risk environments like prisons. This finding encourages healthcare providers to remain vigilant about such nutritional deficiencies and highlights the importance of vitamin C in treatment.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
Improving iron levels
3 people found this helpful
Registered Dietitian Approved. As is common, I developed iron deficiency/anaemia after pregnancy. On my OBGYN's recommendation, I began additional supplementation beyond my prenatal vitamins with Vitron-C three weeks ago. Blood work today shows my anaemia has begun to improve. I chose Vitron-C for its carbonyl iron, which is easily absorbed, and I appreciate that they've added vitamin C to aid with absorption. I'm happy this supplement is working; it doesn't taste bad before swallowing and hasn't caused gastrointestinal issues.
Read More
9
Convenient dosage
1 people found this helpful
Happy with these. My second order finally brought my anaemia into an acceptable range! The doctor had me on OTC iron three times a day. With these, I only need to take them once a day. They lack the iron taste and didn’t cause constipation, so I’m pleased.
Read More
7.5
Stomach-friendly
3 people found this helpful
Good iron. This is one of the few brands that doesn’t upset my stomach. I've been using it for chronic anaemia for a few years now and it's been effective so far.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Rani V, Moretti D, Khetarpaul N, Thankachan P, Zimmermann MB, et al. Vitamin C-Rich Guava Consumed with Mungbean Dal Reduces Anemia and Increases Hemoglobin but not Iron Stores: A Randomized Controlled Trial of Food-to-Food Fortification in Indian Children. J Nutr. 2024;154:3740. doi:10.1016/j.tjnut.2024.10.042
- Atosona A, Larbie C, Apprey C, Annan RA. Pearl millet instant beverage powder enriched with baobab pulp to improve iron and anaemia status of adolescent girls in rural Ghana: a study protocol for a cluster randomised controlled trial. Br J Nutr. 2024;132:565. doi:10.1017/S0007114524001430
- Wang X, Zhu X, Liu Y, Liu H, Xiao Z, et al. Efficacy of vitamin C on chemotherapy-related anemia in pancreatic cancer: study protocol for a randomized controlled trial. Trials. 2024;25:512. doi:10.1186/s13063-024-08345-w
- Balkrishna A, Bhattacharya K, Samanta HS, Tomer M, Varshney A. Advancements in Nano-Mandoor Bhasma: Unravelling the Particle Size-Ascorbic Acid Synergy for Enhanced Iron Bioavailability for Anemia Treatment. Biol Trace Elem Res. 2024. doi:10.1007/s12011-024-04304-3
- Gvozdenko A, Blinov A, Golik A, Rekhman Z, Nagdalian A, et al. Harnessing the Power of a Novel Triple Chelate Complex in Fermented Probiotic Dairy Products: A Promising Solution for Combating Iron Deficiency Anemia. ACS Omega. 2024;9:28594. doi:10.1021/acsomega.4c02664
- Akbari F, Vahedi Larijani L, Rajabi Visroodi E, Hakiminia B. Effect of the treatment of iron deficiency anemia on chronic drug-resistant cough: a rare case report. Daru. 2024;32:967. doi:10.1007/s40199-024-00522-1
- Haile A, Mara S, Belete Y, Dejene T. The Forgotten Disease in the 21st Century: Scurvy Outbreak in Hawassa Central Prison, Hawassa, Sidama, Southern Ethiopia, 2023. Int Med Case Rep J. 2023;16:847. doi:10.2147/IMCRJ.S438833
- Song L, Zhu L, Qiao S, Song L, Zhang M, et al. Preparation, characterization, and bioavailability evaluation of antioxidant phosvitin peptide-ferrous complex. J Sci Food Agric. 2024;104:3090. doi:10.1002/jsfa.13200
- Preston R, Theodorou D, Sinnott K, Wallace D, Kaur A. A cost-effective innovation in anaemia management for paediatric patients with haemodialysis-dependent chronic kidney disease. Pediatr Nephrol. 2025. doi:10.1007/s00467-025-06680-x
- Upadhyay RP, Chowdhury R, Mundra S, Taneja S, Jacob M, et al. Comparative effectiveness of daily therapeutic supplementation with multiple micronutrients and iron-folic acid versus iron-folic acid alone in children with mild-to-moderate anaemia in rural India: an open-label, randomised controlled trial. Lancet Glob Health. 2025;13:e497. doi:10.1016/S2214-109X(24)00559-X
- Thomas T, Kurpad A. Childhood iron-folic acid supplementation in India for mild-to-moderate anaemia. Lancet Glob Health. 2025;13:e383. doi:10.1016/S2214-109X(25)00053-1
- Babah OA, Beňová L, Larsson EC, Hanson C, Afolabi BB. Is an improvement in anaemia and iron levels associated with the risk of early postpartum depression? A cohort study from Lagos, Nigeria. BMC Public Health. 2025;25:808. doi:10.1186/s12889-025-21942-x
- Crispell EH, Cassianni CE, Burt JM, Gonzalez JA, Petsch JL, et al. Design and Staged Implementation of a Multidisciplinary Preoperative Anemia Clinic at a Tertiary Care Medical Center. Anesth Analg. 2025. doi:10.1213/ANE.0000000000007435
- Akpan IJ, Narang M, Zampaglione E, Marshall S, Stefanik D. Iron deficiency anemia in patients with heavy menstrual bleeding: The patients' perspective from diagnosis to treatment. Womens Health (Lond). 2025;21:17455057251321221. doi:10.1177/17455057251321221
- Khalaf K, Fujiyoshi Y, Bechara R. Endoscopic and clinical characteristics of autoimmune atrophic gastritis: Retrospective study. Endosc Int Open. 2025;13:a24774666. doi:10.1055/a-2477-4666
- White F, Polakowski N, Merlington E, Leimanis M, Dudick B, et al. Intravenous Sodium Ferric Gluconate Complex for Hospitalized Pediatric Patients with Iron Deficiency Anemia. Children (Basel). 2025;12. doi:10.3390/children12020189
- Maidana D, Arroyo-Álvarez A, Barreres-Martín G, Arenas-Loriente A, Cepas-Guillen P, et al. Targeting Inflammation and Iron Deficiency in Heart Failure: A Focus on Older Adults. Biomedicines. 2025;13. doi:10.3390/biomedicines13020462
- McDonnell T, Kalra PA. Iron in Chronic Kidney Disease and End-Stage Kidney Disease-Current Trends and Future Direction. Br J Hosp Med (Lond). 2025;86:1. doi:10.12968/hmed.2024.0619
- Orlova P, Meshkov I, Sharikov S, Frolov V, Skuredina A, et al. Amidated and Aminated PMSSO-Hydrogels as a Promising Enzyme-Sensitive Vehicle for Antianemic Drugs. Gels. 2025;11. doi:10.3390/gels11020118
- Al Kindi S, Al-Mamari A, Al-Zadjali S, Al-Rawahi M, Al Madhani A, et al. Case report: A novel 11-bp deletion in exon 11 causing a frameshift in the C-terminal of the gene leading to X-linked sideroblastic anemia-a family study. Front Med (Lausanne). 2024;11:1452873. doi:10.3389/fmed.2024.1452873
- Manna S, Chakrabarti SS, Singh R, Gambhir IS. Serum hepcidin level with iron profile assay might replace bone marrow iron study as a diagnostic tool for evaluation of anemia in elderly without chronic renal disease. J Family Med Prim Care. 2025;14:356. doi:10.4103/jfmpc.jfmpc_34_24
- Kranke P, Weiniger CF, Sultan P, Achebe MO, Filipescu D, et al. Iron deficiency and anemia in pregnancy: a call to action!: -"If you don't take a temperature, you can't find a fever". Int J Obstet Anesth. 2024;62:104298. doi:10.1016/j.ijoa.2024.104298
- Larson LM, Baldi A, Hasan MI, Jones N, Pickle EO, et al. Role of hepcidin on benefits and risks of supplementation with iron syrup and multiple micronutrient powders in Bangladeshi children: a sub-study to a randomized controlled trial. Am J Clin Nutr. 2025. doi:10.1016/j.ajcnut.2025.02.018
- Fijn R, Ablij HC, Knoester PD, Witte AMC. Real-world evaluation of an intravenous iron service for the treatment of iron deficiency with or without anemia. Sci Rep. 2025;15:12093. doi:10.1038/s41598-025-85880-9
- Bhutta ZA, Keats EC, Owais A, González-Fernández D, Udomkesmalee E, et al. What works for anemia reduction among women of reproductive age? Synthesized findings from the exemplars in anemia project. Am J Clin Nutr. 2025;121 Suppl 1:S68. doi:10.1016/j.ajcnut.2024.11.031
- Owais A, Habib A, Ahsan H, Merritt CE, Lee C, et al. Drivers of anemia reduction among women of reproductive age in Pakistan: a mixed-methods country case study. Am J Clin Nutr. 2025;121 Suppl 1:S46. doi:10.1016/j.ajcnut.2024.04.037
- Duan Y, Xu Y, Wei Y, Liu T, Xu T, et al. Bilateral segmental testicular infarction secondary to iron deficiency anemia: a case report. BMC Urol. 2025;25:70. doi:10.1186/s12894-025-01756-0
- Warner MA, Johnson ML, Hanson AC, Fortune E, Flaby GW, et al. Practical Anemia Bundle and Hemoglobin Recovery in Critical Illness: A Randomized Clinical Trial. JAMA Netw Open. 2025;8:e252353. doi:10.1001/jamanetworkopen.2025.2353
- Hidayat MT, Khadijah Maharani SN, Ramadhany ID, Khairani NI, Rahman NA, et al. Controlled release of deferiprone using iron-responsive nanoparticles integrated with dissolving microneedle for novel alternative treatments of β-thalassemia major. Eur J Pharm Biopharm. 2025;210:114702. doi:10.1016/j.ejpb.2025.114702
- Al-Taiar A, Ziyab AH, Hammoud MS, Al-Sabah R, Akhtar S. Anemia in pregnant women: findings from Kuwait birth cohort study. BMC Pregnancy Childbirth. 2025;25:326. doi:10.1186/s12884-025-07439-w
- Sohn SH, Sul H, Kim B, Zang D. Effects of Darbepoetin Alfa and Ferric Derisomaltose Plus Darbepoetin Alfa in Functional Iron-Deficiency Anemia. Int J Mol Sci. 2025;26. doi:10.3390/ijms26052203
- Nagao T, Takahashi K, Takahashi S, Yokomizo R, Samura O, et al. Low-dose ferric carboxymaltose vs. oral iron for improving hemoglobin levels in postpartum East Asian women: A randomized controlled trial. PLoS One. 2025;20:e0319795. doi:10.1371/journal.pone.0319795
- Ozeki Y, Kato J, Ohta Y, Taida T, Horio R, et al. [Efficacy and safety of ferric carboxymaltose in patients with inflammatory bowel disease]. Nihon Shokakibyo Gakkai Zasshi. 2025;122:196. doi:10.11405/nisshoshi.122.196
- Gao Z, Gao Y, Wang Q, Wang Q, Lu P, et al. Study on HIF-PHI combined with iron supplement in treatment of renal anemia in rats. BMC Nephrol. 2025;26:125. doi:10.1186/s12882-025-04045-y
- Liu X, Sun A, Zheng X, Xia M, Liu Y, et al. Combined morphological and molecular approaches to the clinical diagnosis of Necator americanus infection: a case report. J Med Case Rep. 2025;19:100. doi:10.1186/s13256-025-05105-5
- Zhang H, Sun W, Qi J, Qayum A, Li J, et al. Antianemic Activity, Inhibition of Oxidative Stress, and Iron Supplementation in Mice with Iron-Deficiency Anemia through HG-Hawthorn Pectin-Iron(III) Complexes. ACS Appl Bio Mater. 2025;8:2419. doi:10.1021/acsabm.4c01905
- Dogan Y, Dede AM, Erdoğan A. An unusual association: gastric xanthelasma presenting with iron deficiency anemia: a case report. J Med Case Rep. 2025;19:98. doi:10.1186/s13256-025-05133-1
