'
Youtheory Hyaluronic Acid Advanced
SCIENTIFIC SCORE
Questionable
Based on 14 Researches
6.6
USERS' SCORE
Good
Based on 17 Reviews
8.6
Supplement Facts
Serving Size: 2 capsules
Amount Per Serving
%DV
Proprietary BlendBoswellia (Indian Frankincense) (gum) extract, Bromelain (600 GDU/g), Ginger (root) extract, White Willow (bark) (Salix alba) extract, Cayenne (fruit) powder
800 mg
**
Hyaluronic Acid (as Sodium Hyaluronate)
100 mg
**

Top Medical Research Studies

9
Hyaluronic acid effective for back pain
Intraarticular hyaluronic acid versus glucocorticoid injections for nonradicular pain in the lumbar spine.
High relevance, promising findings
We conducted a study to explore whether intraarticular injections of hyaluronic acid (HA) could effectively treat chronic, nonradicular low back pain as compared to glucocorticoids. Sixty patients participated in a well-structured clinical trial where they received either HA or glucocorticoid injections.

Both treatments resulted in significant pain relief, improved function, and enhanced quality of life. Notably, HA was found to be just as effective as glucocorticoids, and showed even better long-term benefits without any reported side effects.
Read More
9
Hyaluronic acid reduces post-surgical fibrosis
Efficacy of topical cross-linked hyaluronic acid hydrogel in preventing post laminectomy/laminotomy fibrosis in a rat model.
Highly relevant to back pain treatment
We examined how cross-linked hyaluronic acid (cHA) hydrogel can help reduce epidural fibrosis after back surgeries, which is a common cause of ongoing pain. In our study with rat models, we compared groups that received cHA to those that did not.

The results showed that cHA treatment led to lower levels of fibrosis and overall healthier spinal structures. The treated groups had more space around the spinal cord and less thickening of protective membranes. Overall, we found that cHA is promising for managing post-surgical back pain by effectively reducing scar tissue formation.
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2
No significant benefit from HA
Viscosupplementation in lumbar facet joint arthropathy: a pilot study.
Low relevance for treatment evaluation
We assessed the effectiveness of hyaluronic acid (HA) injections for lumbar facet joint arthritis in a small pilot study involving thirteen patients. Each participant underwent a thorough evaluation before treatment, using questionnaires to gauge pain levels and disability. After a precise HA injection, we followed up with evaluations six weeks later.

Unfortunately, our findings indicated that there was no significant improvement in back pain or symptoms following the treatment. This suggests that HA may not be effective for managing lumbar facet joint arthritis at this stage.
Read More

Most Useful Reviews

10
Back issue resolved
I have suffered from a back injury for the past ten years. After taking this product for three months—two pills a day—my issue has completely resolved. Occasionally, a slight pain reappears, but taking a couple of pills alleviates it instantly. This product has been life-changing for me.
Read More
9.5
Joint pain relief
Excellent! I bought this for my husband a month ago as he was complaining of joint pain during physical exertion. Within six months, he stated the joints hardly hurt anymore. He now requests more of this treatment, which he takes with glucosamine, chondroitin, and MSM from another company.
Read More
9.5
Joint pain alleviated
Prominent! The quality is excellent. This hyaluronic acid is beneficial. It purifies the skin, reduces wrinkles, and has relieved my joint pain considerably. I recommend using it with collagen for best results.
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 14 Researches
6.6
  • All Researches
9
Hyaluronic acid reduces post-surgical fibrosis
Efficacy of topical cross-linked hyaluronic acid hydrogel in preventing post laminectomy/laminotomy fibrosis in a rat model.
Highly relevant to back pain treatment
We examined how cross-linked hyaluronic acid (cHA) hydrogel can help reduce epidural fibrosis after back surgeries, which is a common cause of ongoing pain. In our study with rat models, we compared groups that received cHA to those that did not.

The results showed that cHA treatment led to lower levels of fibrosis and overall healthier spinal structures. The treated groups had more space around the spinal cord and less thickening of protective membranes. Overall, we found that cHA is promising for managing post-surgical back pain by effectively reducing scar tissue formation.
Read More
9
Hyaluronic acid effective for back pain
Intraarticular hyaluronic acid versus glucocorticoid injections for nonradicular pain in the lumbar spine.
High relevance, promising findings
We conducted a study to explore whether intraarticular injections of hyaluronic acid (HA) could effectively treat chronic, nonradicular low back pain as compared to glucocorticoids. Sixty patients participated in a well-structured clinical trial where they received either HA or glucocorticoid injections.

Both treatments resulted in significant pain relief, improved function, and enhanced quality of life. Notably, HA was found to be just as effective as glucocorticoids, and showed even better long-term benefits without any reported side effects.
Read More
8
Hyaluronic acid improves tissue repair
Augmentation and repair tissue formation of the nucleus pulposus after partial nucleotomy in a rabbit model.
High relevance for back pain treatment.
We examined the effects of hyaluronic acid in healing back pain linked to disc degeneration. In our study, New Zealand white rabbits undergoing a partial nucleotomy received either PGA/HA implants or bioactivated fibrin, while controls underwent the procedure without any treatment.

Our results indicated that the use of PGA/HA implants led to more effective tissue repair, evidenced by a significant increase in type II collagen content, compared to the untreated controls. However, there was no change in the water content of the discs over the six-month period, highlighting that while tissue repair may improve, it may not directly enhance disc hydration or overall disc function.
Read More
8
Sacroiliac joint pain treatment review
Anatomy and pathophysiology of the sacroiliac joint.
Research is highly relevant
We explored the complex nature of chronic pain in the sacroiliac joint, which has long sparked debate due to its anatomical position. This makes accurate diagnosis challenging, often requiring advanced techniques like guided injections.

While there are various treatment options available for sacroiliac joint syndrome, no single method has proven to be ideal. However, using hyaluronic acid through intra-articular viscosupplementation has shown promise in delivering long-lasting pain relief, promoting healthy joint function, and enhancing synovial fluid properties.
Read More
7
Safety and feasibility confirmed
Safety and Feasibility of Intradiscal Administration of Matrilin-3-Primed Adipose-Derived Mesenchymal Stromal Cell Spheroids for Chronic Discogenic Low Back Pain: Phase 1 Clinical Trial.
Moderate relevance for back pain
We explored the safety and feasibility of using hyaluronic acid alongside specially prepared stem cells to treat chronic low back pain. In a small study involving eight patients, everyone received a single injection while being monitored over six months.

Thankfully, there were no reported complications, and six out of eight participants showed meaningful improvements in pain and disability scores. While radiological changes were noted in four patients, the overall findings highlight the potential of this treatment as a safe option for chronic disc-related pain. However, further research is needed to confirm its effectiveness.
Read More

User Reviews

USERS' SCORE
Good
Based on 17 Reviews
8.6
  • All Reviews
  • Positive Reviews
  • Negative Reviews
10
Back issue resolved
I have suffered from a back injury for the past ten years. After taking this product for three months—two pills a day—my issue has completely resolved. Occasionally, a slight pain reappears, but taking a couple of pills alleviates it instantly. This product has been life-changing for me.
Read More
9.5
Joint pain relief
Excellent! I bought this for my husband a month ago as he was complaining of joint pain during physical exertion. Within six months, he stated the joints hardly hurt anymore. He now requests more of this treatment, which he takes with glucosamine, chondroitin, and MSM from another company.
Read More
9.5
Joint pain alleviated
Prominent! The quality is excellent. This hyaluronic acid is beneficial. It purifies the skin, reduces wrinkles, and has relieved my joint pain considerably. I recommend using it with collagen for best results.
9.5
Trauma healing
I highly recommend this for anyone with joint problems! It has alleviated my joint pain and improved my skin condition, which had become dry because of thyroid issues. The capsules are medium-sized and suitable for vegetarians.
9.5
Significant improvement
Excellent! They have helped immensely. I have osteoarthritis and needed something to alleviate the pain. This is the first time I've used hyaluronic acid, and after just a couple of days of taking the capsules, my joints feel significantly better. I highly recommend this product and will continue to purchase it.
Read More
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