Overview
SCIENTIFIC SCORE
Questionable
Based on 14 Researches
6.6
USERS' SCORE
Good
Based on 17 Reviews
8.4
Supplement Facts
Serving Size: 2 capsules
Amount Per Serving
%DV
Proprietary BlendBoswellia (Indian Frankincense) (gum) extract, Bromelain (600 GDU/g), Ginger (root) extract, White Willow (bark) (Salix alba) extract, Cayenne (fruit) powder
800 mg
**
Hyaluronic Acid (as Sodium Hyaluronate)
100 mg
**
Top Medical Research Studies
9
We conducted a study to explore whether intraarticular injections of hyaluronic acid (HA) could effectively treat chronic, nonradicular low back pain as compared to glucocorticoids. Sixty patients participated in a well-structured clinical trial where they received either HA or glucocorticoid injections.
Both treatments resulted in significant pain relief, improved function, and enhanced quality of life. Notably, HA was found to be just as effective as glucocorticoids, and showed even better long-term benefits without any reported side effects.
Both treatments resulted in significant pain relief, improved function, and enhanced quality of life. Notably, HA was found to be just as effective as glucocorticoids, and showed even better long-term benefits without any reported side effects.
Read More
9
We examined how cross-linked hyaluronic acid (cHA) hydrogel can help reduce epidural fibrosis after back surgeries, which is a common cause of ongoing pain. In our study with rat models, we compared groups that received cHA to those that did not.
The results showed that cHA treatment led to lower levels of fibrosis and overall healthier spinal structures. The treated groups had more space around the spinal cord and less thickening of protective membranes. Overall, we found that cHA is promising for managing post-surgical back pain by effectively reducing scar tissue formation.
The results showed that cHA treatment led to lower levels of fibrosis and overall healthier spinal structures. The treated groups had more space around the spinal cord and less thickening of protective membranes. Overall, we found that cHA is promising for managing post-surgical back pain by effectively reducing scar tissue formation.
Read More
2
We assessed the effectiveness of hyaluronic acid (HA) injections for lumbar facet joint arthritis in a small pilot study involving thirteen patients. Each participant underwent a thorough evaluation before treatment, using questionnaires to gauge pain levels and disability. After a precise HA injection, we followed up with evaluations six weeks later.
Unfortunately, our findings indicated that there was no significant improvement in back pain or symptoms following the treatment. This suggests that HA may not be effective for managing lumbar facet joint arthritis at this stage.
Unfortunately, our findings indicated that there was no significant improvement in back pain or symptoms following the treatment. This suggests that HA may not be effective for managing lumbar facet joint arthritis at this stage.
Read More
Most Useful Reviews
10
Back issue resolved
17 people found this helpful
I have suffered from a back injury for the past ten years. After taking this product for three months—two pills a day—my issue has completely resolved. Occasionally, a slight pain reappears, but taking a couple of pills alleviates it instantly. This product has been life-changing for me.
Read More
9
Joint pain relief
4 people found this helpful
Excellent! I bought this for my husband a month ago as he was complaining of joint pain during physical exertion. Within six months, he stated the joints hardly hurt anymore. He now requests more of this treatment, which he takes with glucosamine, chondroitin, and MSM from another company.
Read More
9
Joint pain alleviated
2 people found this helpful
Prominent! The quality is excellent. This hyaluronic acid is beneficial. It purifies the skin, reduces wrinkles, and has relieved my joint pain considerably. I recommend using it with collagen for best results.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 14 Researches
6.6
- All Researches
9
We examined how cross-linked hyaluronic acid (cHA) hydrogel can help reduce epidural fibrosis after back surgeries, which is a common cause of ongoing pain. In our study with rat models, we compared groups that received cHA to those that did not.
The results showed that cHA treatment led to lower levels of fibrosis and overall healthier spinal structures. The treated groups had more space around the spinal cord and less thickening of protective membranes. Overall, we found that cHA is promising for managing post-surgical back pain by effectively reducing scar tissue formation.
The results showed that cHA treatment led to lower levels of fibrosis and overall healthier spinal structures. The treated groups had more space around the spinal cord and less thickening of protective membranes. Overall, we found that cHA is promising for managing post-surgical back pain by effectively reducing scar tissue formation.
Read More
9
We conducted a study to explore whether intraarticular injections of hyaluronic acid (HA) could effectively treat chronic, nonradicular low back pain as compared to glucocorticoids. Sixty patients participated in a well-structured clinical trial where they received either HA or glucocorticoid injections.
Both treatments resulted in significant pain relief, improved function, and enhanced quality of life. Notably, HA was found to be just as effective as glucocorticoids, and showed even better long-term benefits without any reported side effects.
Both treatments resulted in significant pain relief, improved function, and enhanced quality of life. Notably, HA was found to be just as effective as glucocorticoids, and showed even better long-term benefits without any reported side effects.
Read More
8
We examined the effects of hyaluronic acid in healing back pain linked to disc degeneration. In our study, New Zealand white rabbits undergoing a partial nucleotomy received either PGA/HA implants or bioactivated fibrin, while controls underwent the procedure without any treatment.
Our results indicated that the use of PGA/HA implants led to more effective tissue repair, evidenced by a significant increase in type II collagen content, compared to the untreated controls. However, there was no change in the water content of the discs over the six-month period, highlighting that while tissue repair may improve, it may not directly enhance disc hydration or overall disc function.
Our results indicated that the use of PGA/HA implants led to more effective tissue repair, evidenced by a significant increase in type II collagen content, compared to the untreated controls. However, there was no change in the water content of the discs over the six-month period, highlighting that while tissue repair may improve, it may not directly enhance disc hydration or overall disc function.
Read More
8
Sacroiliac joint pain treatment review
We explored the complex nature of chronic pain in the sacroiliac joint, which has long sparked debate due to its anatomical position. This makes accurate diagnosis challenging, often requiring advanced techniques like guided injections.
While there are various treatment options available for sacroiliac joint syndrome, no single method has proven to be ideal. However, using hyaluronic acid through intra-articular viscosupplementation has shown promise in delivering long-lasting pain relief, promoting healthy joint function, and enhancing synovial fluid properties.
While there are various treatment options available for sacroiliac joint syndrome, no single method has proven to be ideal. However, using hyaluronic acid through intra-articular viscosupplementation has shown promise in delivering long-lasting pain relief, promoting healthy joint function, and enhancing synovial fluid properties.
Read More
7
Safety and feasibility confirmed
We explored the safety and feasibility of using hyaluronic acid alongside specially prepared stem cells to treat chronic low back pain. In a small study involving eight patients, everyone received a single injection while being monitored over six months.
Thankfully, there were no reported complications, and six out of eight participants showed meaningful improvements in pain and disability scores. While radiological changes were noted in four patients, the overall findings highlight the potential of this treatment as a safe option for chronic disc-related pain. However, further research is needed to confirm its effectiveness.
Thankfully, there were no reported complications, and six out of eight participants showed meaningful improvements in pain and disability scores. While radiological changes were noted in four patients, the overall findings highlight the potential of this treatment as a safe option for chronic disc-related pain. However, further research is needed to confirm its effectiveness.
Read More
User Reviews
USERS' SCORE
Good
Based on 17 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
10
Back issue resolved
17 people found this helpful
I have suffered from a back injury for the past ten years. After taking this product for three months—two pills a day—my issue has completely resolved. Occasionally, a slight pain reappears, but taking a couple of pills alleviates it instantly. This product has been life-changing for me.
Read More
9
Joint pain relief
4 people found this helpful
Excellent! I bought this for my husband a month ago as he was complaining of joint pain during physical exertion. Within six months, he stated the joints hardly hurt anymore. He now requests more of this treatment, which he takes with glucosamine, chondroitin, and MSM from another company.
Read More
9
Joint pain alleviated
2 people found this helpful
Prominent! The quality is excellent. This hyaluronic acid is beneficial. It purifies the skin, reduces wrinkles, and has relieved my joint pain considerably. I recommend using it with collagen for best results.
Read More
9
Trauma healing
2 people found this helpful
I highly recommend this for anyone with joint problems! It has alleviated my joint pain and improved my skin condition, which had become dry because of thyroid issues. The capsules are medium-sized and suitable for vegetarians.
Read More
9
Significant improvement
2 people found this helpful
Excellent! They have helped immensely. I have osteoarthritis and needed something to alleviate the pain. This is the first time I've used hyaluronic acid, and after just a couple of days of taking the capsules, my joints feel significantly better. I highly recommend this product and will continue to purchase it.
Read More
Frequently Asked Questions
9
Significant improvement
2 people found this helpful
Excellent! They have helped immensely. I have osteoarthritis and needed something to alleviate the pain. This is the first time I've used hyaluronic acid, and after just a couple of days of taking the capsules, my joints feel significantly better. I highly recommend this product and will continue to purchase it.
9
Joint improvement
4 people found this helpful
An excellent supplement for skin and joints! Within two weeks of use, I noticed incredible improvements, including more hydrated skin and less pain in my knees and shoulders.
9
Joint pain relief
4 people found this helpful
Excellent! I bought this for my husband a month ago as he was complaining of joint pain during physical exertion. Within six months, he stated the joints hardly hurt anymore. He now requests more of this treatment, which he takes with glucosamine, chondroitin, and MSM from another company.
7.5
Joint pain relief
1 people found this helpful
A very good and effective product; I noticed a difference in my joint pain within a week of using it! I am quite surprised and satisfied!
2
No improvement noted
These pills were meant to ease my pain, but unfortunately, they didn’t help at all. Perhaps they aren't suitable for my health condition.
9
Joint pain alleviated
2 people found this helpful
Prominent! The quality is excellent. This hyaluronic acid is beneficial. It purifies the skin, reduces wrinkles, and has relieved my joint pain considerably. I recommend using it with collagen for best results.
7.5
Back pain relief
3 people found this helpful
Though the tablets are large and colourful due to cayenne pepper, they must be swallowed quickly. I bought this supplement to maintain joint health, and I’ve noticed my back pain has lessened, and my legs feel lighter. My skin has also become more moisturised.
9
Back aches relief
3 people found this helpful
I love the effects of this product! It alleviates my severe back pain, especially during intense PMS when inflammation is at its peak. These supplements have been a great help for me; I’m hoping for price stability.
7
Safety and feasibility confirmed
We explored the safety and feasibility of using hyaluronic acid alongside specially prepared stem cells to treat chronic low back pain. In a small study involving eight patients, everyone received a single injection while being monitored over six months.
Thankfully, there were no reported complications, and six out of eight participants showed meaningful improvements in pain and disability scores. While radiological changes were noted in four patients, the overall findings highlight the potential of this treatment as a safe option for chronic disc-related pain. However, further research is needed to confirm its effectiveness.
Thankfully, there were no reported complications, and six out of eight participants showed meaningful improvements in pain and disability scores. While radiological changes were noted in four patients, the overall findings highlight the potential of this treatment as a safe option for chronic disc-related pain. However, further research is needed to confirm its effectiveness.
7
We explored how a combination of physical activity and the dietary supplement Cartilox, which includes hyaluronic acid, affects back pain in patients with osteoarthritis. Our study involved 60 patients who received either Cartilox or no supplement alongside their therapy.
While the results suggest that Cartilox could be beneficial for individuals experiencing mild back pain, it appears its effectiveness may not be sufficient to replace non-steroidal anti-inflammatory drugs (NSAIDs) completely.
Overall, we found no adverse effects on biochemical markers, making Cartilox a viable option for patients, including those with other health conditions.
While the results suggest that Cartilox could be beneficial for individuals experiencing mild back pain, it appears its effectiveness may not be sufficient to replace non-steroidal anti-inflammatory drugs (NSAIDs) completely.
Overall, we found no adverse effects on biochemical markers, making Cartilox a viable option for patients, including those with other health conditions.
9
We conducted a study to explore whether intraarticular injections of hyaluronic acid (HA) could effectively treat chronic, nonradicular low back pain as compared to glucocorticoids. Sixty patients participated in a well-structured clinical trial where they received either HA or glucocorticoid injections.
Both treatments resulted in significant pain relief, improved function, and enhanced quality of life. Notably, HA was found to be just as effective as glucocorticoids, and showed even better long-term benefits without any reported side effects.
Both treatments resulted in significant pain relief, improved function, and enhanced quality of life. Notably, HA was found to be just as effective as glucocorticoids, and showed even better long-term benefits without any reported side effects.
4
We examined the effectiveness of hyaluronic acid in managing chronic low back pain originating from facet joint osteoarthritis. Our systematic review analyzed various injectable treatments, focusing on outcomes from randomized clinical trials.
While steroids and local anesthetics showed promising results, hyaluronic acid did not demonstrate significant benefits, unlike other treatments we explored.
Overall, injections for this type of back pain are encouraging, especially with medial branch blocks, but the role of hyaluronic acid remains unclear.
While steroids and local anesthetics showed promising results, hyaluronic acid did not demonstrate significant benefits, unlike other treatments we explored.
Overall, injections for this type of back pain are encouraging, especially with medial branch blocks, but the role of hyaluronic acid remains unclear.
9
We examined how cross-linked hyaluronic acid (cHA) hydrogel can help reduce epidural fibrosis after back surgeries, which is a common cause of ongoing pain. In our study with rat models, we compared groups that received cHA to those that did not.
The results showed that cHA treatment led to lower levels of fibrosis and overall healthier spinal structures. The treated groups had more space around the spinal cord and less thickening of protective membranes. Overall, we found that cHA is promising for managing post-surgical back pain by effectively reducing scar tissue formation.
The results showed that cHA treatment led to lower levels of fibrosis and overall healthier spinal structures. The treated groups had more space around the spinal cord and less thickening of protective membranes. Overall, we found that cHA is promising for managing post-surgical back pain by effectively reducing scar tissue formation.
References
- Lee DH, Park KS, Shin HE, Kim SB, Choi H, et al. Safety and Feasibility of Intradiscal Administration of Matrilin-3-Primed Adipose-Derived Mesenchymal Stromal Cell Spheroids for Chronic Discogenic Low Back Pain: Phase 1 Clinical Trial. Int J Mol Sci. 2023;24. doi:10.3390/ijms242316827
- Goode AP, Cleveland RJ, Kraus VB, Taylor KA, George SZ, et al. Biomarkers and longitudinal changes in lumbar spine degeneration and low back pain: the Johnston County Osteoarthritis Project. Osteoarthritis Cartilage. 2023;31:809. doi:10.1016/j.joca.2023.02.005
- Shavlovskaya OA. [Complex effects of physical exertion with dietary supplements Cartilox in pain syndrome effectiveness and safety evaluation]. Vopr Kurortol Fizioter Lech Fiz Kult. 2022;99:20. doi:10.17116/kurort20229904120
- Baroncini A, Maffulli N, Eschweiler J, Knobe M, Tingart M, et al. Management of facet joints osteoarthritis associated with chronic low back pain: A systematic review. Surgeon. 2021;19:e512. doi:10.1016/j.surge.2020.12.004
- Farì G, Santagati D, Pignatelli G, Scacco V, Renna D, et al. Collagen Peptides, in Association with Vitamin C, Sodium Hyaluronate, Manganese and Copper, as Part of the Rehabilitation Project in the Treatment of Chronic Low Back Pain. Endocr Metab Immune Disord Drug Targets. 2022;22:108. doi:10.2174/1871530321666210210153619
- Amirdelfan K, Bae H, McJunkin T, DePalma M, Kim K, et al. Allogeneic mesenchymal precursor cells treatment for chronic low back pain associated with degenerative disc disease: a prospective randomized, placebo-controlled 36-month study of safety and efficacy. Spine J. 2021;21:212. doi:10.1016/j.spinee.2020.10.004
- Annaswamy TM, Armstead C, Carlson L, Elkins NJ, Kocak D, et al. Intra-articular Triamcinolone Versus Hyaluronate Injections for Low Back Pain With Symptoms Suggestive of Lumbar Zygapophyseal Joint Arthropathy: A Pragmatic, Double-Blind Randomized Controlled Trial. Am J Phys Med Rehabil. 2018;97:278. doi:10.1097/PHM.0000000000000879
- Kumar H, Ha DH, Lee EJ, Park JH, Shim JH, et al. Safety and tolerability of intradiscal implantation of combined autologous adipose-derived mesenchymal stem cells and hyaluronic acid in patients with chronic discogenic low back pain: 1-year follow-up of a phase I study. Stem Cell Res Ther. 2017;8:262. doi:10.1186/s13287-017-0710-3
- Wu CY, Huang YH, Lee JS, Tai TW, Wu PT, et al. Efficacy of topical cross-linked hyaluronic acid hydrogel in preventing post laminectomy/laminotomy fibrosis in a rat model. J Orthop Res. 2016;34:299. doi:10.1002/jor.23001
- Endres M, Zenclussen ML, Casalis PA, Freymann U, Gil Garcia S, et al. Augmentation and repair tissue formation of the nucleus pulposus after partial nucleotomy in a rabbit model. Tissue Cell. 2014;46:505. doi:10.1016/j.tice.2014.09.003
- Cleary M, Keating C, Poynton AR. Viscosupplementation in lumbar facet joint arthropathy: a pilot study. J Spinal Disord Tech. 2008;21:29. doi:10.1097/BSD.0b013e318057720c
- Fuchs S, Erbe T, Fischer HL, Tibesku CO. Intraarticular hyaluronic acid versus glucocorticoid injections for nonradicular pain in the lumbar spine. J Vasc Interv Radiol. 2005;16:1493.
- Calvillo O, Skaribas I, Turnipseed J. Anatomy and pathophysiology of the sacroiliac joint. Curr Rev Pain. 2000;4:356.
- Srejic U, Calvillo O, Kabakibou K. Viscosupplementation: a new concept in the treatment of sacroiliac joint syndrome: a preliminary report of four cases. Reg Anesth Pain Med. 1999;24:84.
